Biosensor Offers Real-Time Tracking of Drugs in Blood (video) American Association for the Advancement of Science Share Print E-Mail Loading video... Caption Scientists have developed an aptamer-based biosensor capable of continuously tracking drugs in the bloodstream in real-time. The sensor consists of shape-changing probes, switches that can only be flipped by the right molecule. The greater the concentration of a drug, the more switches will be flipped. The biosensor is versatile; it can be reconfigured to measure different drugs by swapping out the probes with different ones. This video illustrates individual drug molecules at different concentrations flipping switches in the aptamer-based apparatus. This video relates to a paper that appeared in the Nov. 27, 2013, issue of Science Translational Medicine, published by AAAS. The paper, by Dr. B.S. Ferguson at University of California, Santa Barbara in Santa Barbara, Calif., and colleagues was titled, "Real-Time, Aptamer-Based Tracking of Circulating Therapeutic Agents in Living Animals." Credit Courtesy of the H.T. Soh Laboratory, University of California, Santa Barbara Usage Restrictions Please cite the owner of the video when publishing. This video may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact Science for permission. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.