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Contact: Evan Lerner
University of Pennsylvania

Dynamic Model

Caption: Researchers at the University of Pennsylvania, Brown University and ETH Zurich have used a series of experiments to develop a dynamic model of the stresses that stretch growing tissue. This model is the first to take into account the complicated feedback effects of cells' molecular motors, which can respond to external stress by pulling harder on their environment, eventually tearing the tissue apart. When cells in developing tissue pull on each other in these dogbone-shaped wells, they first break in the long middle section.

Credit: University of Pennsylvania

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Related news release: Researchers at Penn help develop a dynamic model of tissue failure

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