Contact: Jeff Falk
Caption: Scientists at Rice University regulated the size of vesicular organelles called peroxisomes and the density of protein motors on their surfaces to analyze how the motors cooperate as they move the vesicles inside cells. The PEX 3/FKBP receptors, when incubated with rapalog, allow transiently expressed kinesin and myosinVa motors to be coupled to vesicle surfaces via FRB protein fusions. Once coupled to the vesicles, the motors pull them along cytoskeleton filaments (bottom).
Credit: Diehl Lab/Rice University
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Related news release: Some motor proteins cooperate better than others