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Contact: Catherine Kolf
Johns Hopkins Medicine

Nerve Cells Light Up As They Respond To Pain

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Caption: Nerve cells in the skin of a mouse ear light up when activated. Application of capsaicin activates only pain-sensing nerve cells, in a dose-dependent fashion, while potassium chloride (KCl) activates all nerve cells present. The video shows more nerves lighting up each time during the sequential application of a low dose of capsaicin, a higher dose of capsaicin (6 sec), and then KCl (10 sec).

Credit: Yushim Kim and Xinzhong Dong, courtesy of Neuron

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