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Contact: Lynn Yarris
DOE/Lawrence Berkeley National Laboratory

Jennifer Doudna and Sam Sternberg, DOE/Lawrence Berkeley National Laboratory

Caption: Jennifer Doudna and Samuel Sternberg used a combination of single-molecule imaging and bulk biochemical experiments to show how the RNA-guided Cas9 enzyme is able to locate specific 20-base-pair target sequences within genomes that are millions to billions of base pairs long.

Credit: Photo by Roy Kaltschmdit, Berkeley Lab

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