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Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University

Antibody Footprints

Caption: These images illustrate antibody "footprints" outlined in yellow on the surface of a virus called EV71. Three distinct proteins - out of a total of 180 - that make up the viral capsid are outlined in blue, green, and red. The neutralizing antibodies E18 (A) and E19 (B), used in this study were found to bind to the viral proteins where the colors are bright. The E18 antibody causes the viral capsid to open, resulting in the loss of the viral genome, suggesting the virus no longer has the ability to replicate in the human host.

Credit: (Department of Biological Sciences, Purdue University)

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