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Contact: Dr. Daniel Engel
University of Bonn

Weapon of the Immune System with a Built-In Safety Catch

Caption: In a urinary tract infection, the migration of neutrophils (red cell) from the blood (red vessel, above) to the infection is only possible following a consultation between helper (yellow) and sentinel macrophages (green). Via the positive signal of the helper macrophages (thumbs up), the sentinel macrophage produces the protein CXCL2 (key) which allows the neutrophils to migrate through the basal membrane of the uroepithelium (chain with lock).

Credit: Graphic: P. Schreiner and M. Gerhards/UKB

Usage Restrictions: The graphic may be used with the press release.

Related news release: Immune cells need a second opinion

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