Mdm2 Suppresses Cell Transformation (image) Rockefeller University Press Caption Mouse cells fail to thrive in suspension cultures when wild-type Mdm2 is expressed (left), but expression of a mutant form of Mdm2 (right), in combination with PGAM and an oncogenic protein called Ras, enhances glycolysis and promotes cell transformation (right). Credit Mikawa et al., 2014 Usage Restrictions Reporters may freely use these materials in news coverage, with the appropriate credit information. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.