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Contact: Jaclyn Jansen
jjansen@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Cells Can Randomly Use One Copy of a Gene Over the Other

Caption: The nucleus of every cell in our body contains two copies of each gene, encoded in our DNA (nuclei outlined in purple, DNA for individual genes labeled in red). In general, these copies are used equally, but on occasion, the cell chooses to use just one (seen here in yellow/green). Today, researchers from CSHL have discovered that this truly random process, known as monoallelic gene expression, occurs during development, offering an unexpected glimpse of the significant variability in gene expression.

Credit: David Spector, Cold Spring Harbor Laboratory

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Related news release: Like mom or dad? Some cells randomly express one parent's version of a gene over the other


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