Contact: Evan Lerner
University of Pennsylvania
Caption: To migrate to other parts of the body, a cell's nucleus must squeeze through pores -- and survive the trip. Too much lamin-A in the nucleus and it will be too stiff to fit through pores; too little and it will break apart in the process, killing the cell. Knowing the optimal level of lamin-A for keeping cells in place could have applications in cancer treatment and stem cell therapies.
Credit: University of Pennsylvania, Journal of Cell Biology
Usage Restrictions: With credit.
Related news release: Penn researchers show nuclear stiffness keeps stem cells and cancer cells in place