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Contact: Laura S. Leifman
aura.sivitz@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

HIV Spike

Caption: This is a representation of an image taken with an electron microscope of one of the numerous spikes that jut out of the surface of HIV. The green area marks the location of the V1V2 region, where CAP256-VRC26 and other broadly neutralizing HIV antibodies bind. The blue, red and circled areas mark the three other sites where most known broadly neutralizing HIV antibodies bind. The flat area at the top represents the surface membrane of the virus.

Credit: NIAID

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