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Contact: Beth Kwon
byk2102@columbia.edu
212-854-6581
Columbia University

Stimulated Raman Scattering Microscopy

Caption: Images of stimulated Raman scattering (SRS) microscopy coupled with alkyne tags for visualizing a broad spectrum of small molecule dynamics in live cells and animals, including metabolic incorporation of small molecule precursors of nucleic acids for de novo synthesis of DNA (magenta image) and RNA (cyan image), amino acids for newly synthesized proteins (red image), lipids for choline phospholipids (yellow image) and triglycerides (blue image); and delivery pathways of small molecule drugs in mouse ear tissues (green image).

Credit: Lu Wei of Columbia University

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Related news release: Imaging dynamics of small biomolecules inside live cells


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