This is the Geodesic Positioning of 25 subjects in AHA atlas coordinates with colors representing AHA parcellation; black area located in anterior apical segment 13 showing structural phenotype difference between ischemic and non-ischemic cardiomyopathy at end-systole. Bottom shows smaller wall thickening during maximum contraction at end-systole at the location of infarction (segment 13) in ischemic population as signaled by Jacobian of geodesic coordinates indexed to the segment. Left: mean Jacobian for ischemic population, Right: mean Jacobian for the non-ischemic population. Note ischemic group has significantly smaller myocardial tissue volume. (Cardiac study done in collaboration with Dr. Robert G. Weiss, Director of DW Reynolds Clinical Cardiovascular Research Center in the division of Cardiology in the Johns Hopkins School of Medicine, and Dr. Siamak Ardekani. Data collected on an Aquilion 64(32) multi-detector computed tomography scanner, Toshiba Medical Systems Corporation, Japan; in plane resolution 0.36 × 0.36 mm (0.45 × 0.45 mm), out of plane thickness = 0.5 mm).