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Contact: Susan Gammon, Ph.D., M.B.A.
sgammon@sanfordburnham.org
858-610-3808
Sanford-Burnham Medical Research Institute

Muscle Regeneration in Duchenne Muscular Dystrophy

Caption: HDAC inhibitors (HDACi) promote muscle regeneration in a mouse model of Duchenne Muscular Dystrophy at early stages of disease by targeting fibro-adipogenic progenitors (FAPs). Staining of FAPs from muscles of HDACi-treated young mdx mice reveals presence of differentiated muscle cells (green) at the expense of fat cells (red). Nuclei are stained in blue.

Credit: Lorenzo Puri, M.D.

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Related news release: Regenerating muscle in Duchenne muscular dystrophy: Age matters


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