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Contact: Michael Jantsch
michael.jantsch@univie.ac.at
43-142-775-6230
University of Vienna

Structure

Caption: This is a model of the RNA-binding domain of ADAR1 (green), bound to double-stranded RNA (yellow). Transportin1, which mediates the nuclear transport of ADAR1, is depicted in gray. The structural model reveals that ADAR1 cannot enter the nucleus when bound to RNA, as RNA (yellow) and Transportin1 (gray) clash.

Credit: Copyright: PNAS

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