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Contact: Kelly Blake
University of Maryland


Caption: The hippocampus (pictured left), a seahorse-shaped structure located in the brain's temporal lobe, is affected early in the neuropathologic process of Alzheimer's disease, and greater than normal shrinkage occurs as the disease progresses. Healthy asymptomatic older adults who carry the APOE- e4 allele also show greater rates of hippocampal atrophy, which can be attenuated by being physically active.

Credit: Laszlo Seress/Wikimedia Commons

Usage Restrictions: Wikimedia Commons

Related news release: Physical activity keeps hippocampus healthy in people at risk for Alzheimer's disease

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