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Contact: Karl Bates
karl.bates@duke.edu
919-681-8054
Duke University

Receptor

Caption: This ribbon diagram shows three ankyrin repeats, a common structure found in receptor proteins that sense either cold or hot temperatures. A Duke team has identified three single-point mutations that can invert temperature-sensitivity, turning a cold-sensor into a heat-sensor. All three of these mutations are located in on a single ankyrin repeat.

Credit: Grandl Lab, Duke University

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