LovD9 (image) University of California - Los Angeles Caption This is a representation of the chemical structure of the mutated enzyme LovD9 used to manufacture the cholesterol-reducing drug simvastatin. The structure of the mutated enzyme and why it is effective in producing simvastatin was determined through X-ray crystallography and molecular dynamics simulations at UCLA. Credit UCLA/Codexis Usage Restrictions None Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.