[ Back to EurekAlert! ]

Contact: Stuart Wolpert
swolpert@support.ucla.edu
310-206-0511
University of California - Los Angeles

LovD9

Caption: This is a representation of the chemical structure of the mutated enzyme LovD9 used to manufacture the cholesterol-reducing drug simvastatin. The structure of the mutated enzyme and why it is effective in producing simvastatin was determined through X-ray crystallography and molecular dynamics simulations at UCLA.

Credit: UCLA/Codexis

Usage Restrictions: None

Related news release: Scientists reveal structural secrets of enzyme used to make popular anti-cholesterol drug


[ Back to EurekAlert! ]