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Contact: Stuart Wolpert
University of California - Los Angeles


Caption: This is a representation of the chemical structure of the mutated enzyme LovD9 used to manufacture the cholesterol-reducing drug simvastatin. The structure of the mutated enzyme and why it is effective in producing simvastatin was determined through X-ray crystallography and molecular dynamics simulations at UCLA.

Credit: UCLA/Codexis

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Related news release: Scientists reveal structural secrets of enzyme used to make popular anti-cholesterol drug

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