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Contact: Sanjeevi Sivasankar
sivasank@iastate.edu
515-294-1220
Iowa State University

Catch Bond Mechanics

Caption: This ribbon diagram shows a pulling force applied to two common adhesion proteins called cadherins (red and blue) bound together in an X-shape. The green spheres represent calcium ions while the cyan and orange stick figures correspond to amino acids brought together as the force is applied. The hydrogen bonds that form between the amino acids create catch bonds that get stronger when pulled.

Credit: Image courtesy of Sanjeevi Sivasankar/Iowa State University

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Related news release: Iowa State, Ames Lab researchers find the mechanism that forms cell-to-cell catch bonds


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