Interpenetrating Alginate Network (image) Harvard University Caption This diagram shows a cell encapsulated in an interpenetrating network of alginate (blue) and reconstituted basement membrane matrix (green). Integrin receptors on the cell membrane bind to ligands in the extracellular matrix. The alginate network stiffens the matrix without creating new biochemical bonds so that the researchers can study stiffness in isolation. Credit Image courtesy of Ovijit Chaudhuri, Harvard University. Usage Restrictions Editorial use only. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.