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Contact: Katherine Unger Baillie
University of Pennsylvania

Mice with Reduced OGT

Caption: Mice with genetically reduced levels of the protein OGT in the placenta were shorter and leaner than normal mice. Similar phenotypes are seen in mice born to mothers who experienced stress early in pregnancy. The findings support the idea that mitochondrial dysfunction in the hypothalamus is affected by low OGT levels.

Credit: University of Pennsylvania

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Related news release: Penn team links placental marker of prenatal stress to brain mitochondrial dysfunction

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