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Contact: Guenter von Kiedrowski


Caption: Can 20 trisoligonucleotides with 20×3 individual sequences be programmed to self-assemble into a DNA dodecahedron? The answer is yes if one starts from a new generation of trisoligonucleotides based on C3h-symmetric linkers with proper flexibility. The resulting dodecahedron has C1 symmetry and may facilitate the construction of multimodular scaffolds in the future.

Credit: (C) Wiley-VCH

Usage Restrictions: Permission to use with appropriate credit and link to http://dx.doi.org/10.1002/anie.200702682

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