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Contact: Catherine Zandonella
czandone@princeton.edu
609-258-0541
Princeton University

Mammary Tissue

Caption: A team led by researchers at Princeton University has found that a gene known as Metadherin, or MTDH, promotes the survival of tumor-initiating cells via the interaction with a second molecule called SND1. Mammary tissue was taken from mice (stained red for visualization) that were genetically engineered to develop breast cancer in the presence (left) or absence (right) of MTDH. The dark-pink, cloud-like structures indicate the initiation of mammary tumors, which were largely suppressed by loss of the MTDH gene.

Credit: Image courtesy of Yibin Kang, Department of Molecular Biology

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