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Contact: Dr. Stefan Jentsch
jentsch@biochem.mpg.de
49-898-578-3010
Max-Planck-Gesellschaft

Formaldehyde

Caption: Formaldehyde, generated in cells or derived from the environment, can crosslink DNA to proteins, which interferes with DNA replication. The newly identified repair protein Wss1 chops down the protein component of DNA-protein crosslinks, thereby enabling cells to complete replication.

Credit: MPI of Biochemistry/ S. Jentsch

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Related news release: Cellular defence against fatal associations between proteins and DNA


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