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Contact: Sarah Avery
Duke University Medical Center


Caption: Microcomputed tomography (3D X-ray) images (top) and histology images (bottom) of the knees of mice fed a very high fat diet containing omega 3 fatty acid supplement (left) or only omega 6 fatty acids (right) after a knee injury. The omega 6 diet showed abnormal bone remodeling and calcified tissue formation in the joint (white arrow). The omega 6 diet also showed significant loss of cartilage (red staining, yellow arrowhead) and increased joint inflammation.

Credit: Duke Orthopaedic Research Laboratories

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