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Contact: Lucky Tran
Columbia University Medical Center

Diseased Retinal Cells are Treated with Gene Therapy

Caption: In normal, or wild-type, retinal cells (left), the protein actin forms the cell's cytoskeleton, creating an internal support structure that looks like a series of connected hexagons. In cells with MFRP mutations (center), this structure fails to form, compromising cellular function. When diseased retinal cells are treated with gene therapy to insert normal copies of MFRP (right), the cell's cytoskeleton and function are restored.

Credit: Lab of Stephen H. Tsang, M.D., Ph.D./Columbia University Medical Center.

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