Contact: Julia Evangelou Strait
Washington University School of Medicine
Caption: A new study suggests uric acid may play a role in causing metabolic syndrome, a cluster of risk factors that increases the risk of heart disease and type 2 diabetes. Normally, GLUT9 (green) is abundant in the membranes of cells lining the interior of the gut, where it transports uric acid out of the body. Mice lacking GLUT9 only in the gut show high levels of uric acid in the blood and quickly develop markers of metabolic syndrome. Cell nuclei are in blue.
Credit: Moley Lab
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