[ Back to EurekAlert! ]

Contact: Holly Evarts
holly.evarts@columbia.edu
347-453-7408
Columbia University School of Engineering and Applied Science

Damage Analysis of BBB-opened Brain Regions

Caption: Histological examination of (A, C) left (BBB-opened) and (B, D) corresponding right (no ultrasound) hippocampi. No microscopic tissue damage was observed in the BBB-opened hippocampus at 0.51 MPa (A), same as in the intact right hippocampus on the same section (B). Minor microhemorrhage is noticeable in one location (box) in the hippocampus sonicated at 0.84 MPa (C), compared to no damage in nonsonicated hippocampus (D). The insert shows magnified image of the region in the box. Scale bar represents 1 mm.

Credit: Elisa Konofagou

Usage Restrictions: None

Related news release: New non-invasive technique controls size of molecules penetrating the blood-brain barrier


[ Back to EurekAlert! ]