Contact: Thomas Boehm
Caption: The normal mouse thymus (left) contains only a small fraction of B-cells (red). If the gene FOXN4 is activated, a fish-like thymus with many B-cells develops. This state is likely to have existed about 500 million years ago, at the time when the first vertebrates emerged.
Credit: Max Planck Institute of Immunobiology & Epigenetics
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