Contact: Katherine Unger Baillie
University of Pennsylvania
Caption: Penn and NIH researchers have demonstrated a never-before characterized type of cell movement. In this video, a cell's vimentin cytoskeleton (green) pulls the nucleus (red) forward to generate a high-pressure protrusion, called a lobopodia, inside a cell migrating in a physiological 3D extracellular matrix. This time-lapse movie is 30 minutes of time compressed into 4 seconds (450x speed).
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Related news release: Penn-NIH team discover new type of cell movement