A Changed Brain (image) Rockefeller University Caption Chemical changes to histones, proteins that provide structure for DNA, can alter gene expression. Above, individual spots represent acetylated histones in a brain region called the hippocampus. The researchers found the loss of acetyl groups from histones is key to the development of anxiety- and depression-like behaviors in stressed mice. Credit Carla Nasca Usage Restrictions None Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.