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Contact: Paul Preuss
paul_preuss@lbl.gov
510-486-6249
DOE/Lawrence Berkeley National Laboratory
Caption: The four domains of XPD: the helicases HD2 (green) and HD1 (blue), the iron-sulfur complex 4FeS (rust), and the Arch (purple). Sites of mutations that cause xeroderma pigmentosum are shown in red, those causing both xeroderma pigmentosum and Cockayne syndrome in gold, and those of trichothiodystrophy in purple. A strand of unwound DNA is shown passing under the arch.
Credit: Lawrence Berkeley National Laboratory
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Related news release: The structure of XPD sheds light on cancer and aging
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