Stemming a Tide of Wrinkles (image) University of Michigan Health System Share Print E-Mail Caption Wrinkles form because the skin's collagen breaks down with age and sun exposure. Some treatments encourage new collagen to form. Left: Fibroblasts (collagen-making cells), shown in yellow, in aging skin. Center: After the injection of the wrinkle filler Restylane, the fibroblasts begin to stretch. Right: Stretched fibroblasts have created new collagen (in red). Credit Laura van Goor, University of Michigan Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.