Contact: Anne Rueter
University of Michigan Health System
Caption: Wrinkles form because the skin's collagen breaks down with age and sun exposure. Some treatments encourage new collagen to form. Left: Fibroblasts (collagen-making cells), shown in yellow, in aging skin. Center: After the injection of the wrinkle filler Restylane, the fibroblasts begin to stretch. Right: Stretched fibroblasts have created new collagen (in red).
Credit: Laura van Goor, University of Michigan
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