Contact: Karen Kreeger
karen.kreeegr@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

New Role for a 'Foxy Old Gene'

Caption: Liver cells from mice that do not express FOXA2 (Mutant mice accumulated bile salts and failed to detoxify them properly, which resulted in liver damage.). The liver cells in this image show an accumulation of proteins that are used by cells to degrade unwanted substances.

Credit: Klaus Kaestner, Ph.D., University of Pennsylvania School of Medicine; Nature Medicine

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Related news release: Penn researchers find a new role for a 'Foxy Old Gene'