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Cell-Cycle Regulation by an Adenovirus (2 of 2)

Caption: The image depicts an artistic rendition of the outer shell of the adenoviruses. The shell is a polyhedron with 20 faces (icosohedron) and 12 antenna-like projections. Each face of the polyhedron portrays the molecular changes that the virus induces in the gene expression and epigenetic landscape of the host cell to produce viral progenies. This image relates to an article that appeared in the Aug. 22, 2008, issue of Science, published by AAAS. The study, by Dr. R. Ferrari and colleagues at University of California, Los Angeles in Los Angeles, was titled "Epigenetic Reprogramming by Adenovirus e1a."

Credit: Image courtesy of Samiva Kordestani and Gianluca Ferrari

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