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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 1-25 out of 3754.

1 | 2 | 3 | 4 | 5 > >>

Public Release: 3-Jul-2015
Science Advances
REM sleep critical for young brain development; medication interferes
Rapid eye movement or REM sleep actively converts waking experiences into lasting memories and abilities in young brains reports a new study from Washington State University Spokane. The finding, published in Science Advances, broadens the understanding of children's sleep needs and calls into question the increasing use of REM-disrupting medications such as stimulants and antidepressants.
National Institutes of Health

Contact: Marcos Frank
Washington State University

Public Release: 2-Jul-2015
Cell Reports
Long-term memories are maintained by prion-like proteins
Research from Eric Kandel's lab has uncovered further evidence of a system in the brain that persistently maintains memories for long periods of time.
National Institutes of Health

Contact: Karin Eskenazi
Columbia University Medical Center

Public Release: 2-Jul-2015
Cell Stem Cell
New measurements reveal differences between stem cells for treating retinal degeneration
By growing two types of stem cells in a '3-D culture' and measuring their ability to produce retinal cells, a team lead by St. Jude Children's Research Hospital researchers has found one cell type to be better at producing retinal cells.
National Institutes of Health, Howard Hughes Medical Institute, Alex's Lemonade Stand Foundation for Childhood Cancer and ALSAC

Contact: Frannie Marmorstein
St. Jude Children's Research Hospital

Public Release: 2-Jul-2015
American Journal of Hypertension
Two new studies on the connection between hypertension and cognitive decline
With the number of individuals affected by cognitive decline expected to rise over the next few decades, investigating its potential causes is of major public health interest. Two new studies published today in the American Journal of Hypertension delve into the connection between hypertension and cognitive decline.
NIH/National Heart, Lung, and Blood Institute, National Institutes of Health, US Department of Health and Human Services

Contact: Molly Grote
Oxford University Press USA

Public Release: 2-Jul-2015
Journal of the American Heart Association
Review indicates where cardio benefits of exercise may lie
A systematic review of 160 clinical trials of the cardiometabolic benefits of exercise shows which health indicators improve most with physical activity and for whom. For example, some of the benefits are greater for men, people under 50 and among those battling type 2 diabetes or other cardiovascular conditions.
National Institutes of Health, Brown University, Indiana University

Contact: David Orenstein
Brown University

Public Release: 2-Jul-2015
Mosquito-borne viruses subject of $4 million in federal grants to Pitt vaccine researchers
Scientists at the University of Pittsburgh Center for Vaccine Research recently received nearly $4 million through five federal grants to study a group of related mosquito-borne viruses. The ultimate goal is to develop vaccines and therapies against the deadly diseases.
National Institutes of Health, US Department of Defense

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 2-Jul-2015
Investigational HIV vaccine regimen shows encouraging results in non-human primates
Johnson & Johnson announced today that scientists at Beth Israel Deaconess Medical Center, Crucell Holland B.V, and several other collaborators today published results from a preclinical study of an HIV vaccine regimen used in in non-human primates. The study, published in the online edition of Science, suggests that a 'heterologous prime-boost' vaccine regimen -- could ultimately prove to be a strategy for protecting against global human immunodeficiency virus infection.
National Institutes of Health, Bill & Melinda Gates Foundation, The Ragon Institute of Massachusetts General Hospital, MIT, Harvard

Contact: Seema Kumar
Johnson & Johnson

Public Release: 2-Jul-2015
Viral protein in their sights
A team from Harvard Medical School, using electron cryomicroscopy, has for the first time revealed at the atomic level the structure of a protein required for viral replication in vesicular stomatitis virus, a virus that is a model for a group of RNA viruses that includes Ebola and other threats to human health.
National Institutes of Health, New England Regional Center of Excellence for Biodefense and Emerging Infectious Diseases

Contact: David Cameron
Harvard Medical School

Public Release: 2-Jul-2015
Genetic variation determines response to anti-diabetic drug
In the first study of its kind, researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. They aim to apply this knowledge to develop personalized approaches to treating diabetes and other metabolic disorders.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, JPB Foundation

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 2-Jul-2015
Cell Reports
Researchers reveal a genetic blueprint for cartilage
Cartilage does a lot more than determine the shapes of people's ears and noses. It also enables people to breathe and to form healthy bones -- two processes essential to life. In a study published in Cell Reports, USC Stem Cell researcher Xinjun He and University of Tokyo researcher Shinsuke Ohba explore how a protein called Sox9 regulates the production of cartilage.
National Institutes of Health, Japan Society for the Promotion of Science, Takeda Science Foundation, Graduate Program for Leaders in Life Innovation, Core-to-Core Program A Advanced Research Networks

Contact: Leslie Ridgeway
University of Southern California - Health Sciences

Public Release: 2-Jul-2015
Vanderbilt research could lead to vaccines and treatment for dengue virus
Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus.
National Institutes of Health

Contact: Craig Boerner
Vanderbilt University Medical Center

Public Release: 2-Jul-2015
Molecular Cell
Melanoma mutation rewires cell metabolism
A mutation found in most melanomas rewires cancer cells' metabolism, making them dependent on a ketogenesis enzyme. The finding points to possible strategies for countering resistance to existing drugs that target the B-raf V600E mutation, or potential alternatives to those drugs. It may also explain why the V600E mutation in particular is so common in melanomas.
NIH/National Cancer Institute, American Cancer Society, Leukemia and Lymphoma Society

Contact: Judy Fortin
Emory Health Sciences

Public Release: 2-Jul-2015
Developmental Cell
Hippo dances with hormones
In fruit flies, the abnormal growth induced by Hippo pathway disruption depends on genes involved in responding to the steroid hormone ecdysone. This has potential implications for human biology, since the Hippo pathway is involved in suppressing cancer growth and forming embryonic stem cells.
NIH/National Institute of General Medical Sciences, NIH/National Cancer Institute

Contact: Quinn Eastman
Emory Health Sciences

Public Release: 2-Jul-2015
Advanced Functional Materials
Elastic gel to heal wounds
A team of bioengineers at Brigham and Women's Hospital has developed a new protein-based gel that, when exposed to light, mimics many of the properties of elastic tissue, such as skin and blood vessels. In a paper published in Advanced Functional Materials, the research team reports on the new material's key properties, many of which can be finely tuned, and on the results of using the material in preclinical models of wound healing.
National Institutes of Health, National Science Foundation

Contact: Haley Bridger
Brigham and Women's Hospital

Public Release: 2-Jul-2015
Study shows novel HIV vaccine regimen provides robust protection in non-human primates
A new study led by scientists at Beth Israel Deaconess Medical Center shows than an HIV-1 vaccine regimen, involving a viral vector boosted with a purified envelope protein, provided complete protection in half of the vaccinated non-human primates (NHPs) against a series of six repeated challenges with simian immunodeficiency virus (SIV), a virus similar to HIV that infects NHPs.
National Institutes of Health, Bill & Melinda Gates Foundation, Ragon Institute of MGH, Massachusetts Institute of Technology, Harvard University

Contact: Bonnie Prescott
Beth Israel Deaconess Medical Center

Public Release: 1-Jul-2015
American Journal of Occupational Therapy
Preemies at high risk of autism don't show typical signs of disorder in early infancy
Premature babies are at an increased risk for developing autism spectrum disorder. But a small study indicates that preemies who avoid eye contact in early infancy are less likely to demonstrate symptoms of autism at age 2 than preemies who maintain eye contact during early interactions, according to new research at Washington University School of Medicine in St. Louis.
National Institutes of Health, Washington University Intellectual and Developmental Disabilities Research Center, NIH/National Center for Advancing Translational Sciences

Contact: Judy Martin Finch
Washington University School of Medicine

Public Release: 1-Jul-2015
Molecular Psychiatry
Brain activity predicts promiscuity and problem drinking
A new pair of brain-imaging studies suggest that researchers may be able to predict how likely young adults are to develop problem drinking or risky sexual behavior in response to stress. The research is part of the ongoing Duke Neurogenetics Study or DNS, which began in 2010 to better understand how interactions between the brain, genome, and environment shape risky behaviors predicting mental illnesses including depression, anxiety, and addiction.
Duke University, National Institutes of Health, Howard Hughes Medical Institute

Contact: Karl Bates
Duke University

Public Release: 1-Jul-2015
EMBO Molecular Medicine
Penn team identifies gene responsible for some cases of male infertility
Oftentimes men with a type of infertility called azoospermia don't know the underlying cause of their condition. But new research led by University of Pennsylvania scientists suggests that mutations in an X chromosome gene called TEX11 are responsible for a significant number of cases of infertility -- an estimated 1 percent of cases of non-obstructive azoospermia.
Howard Hughes Medical Institute, NIH/National Institute of General Medical Sciences

Contact: Katherine Unger Baillie
University of Pennsylvania

Public Release: 1-Jul-2015
Institute for Biomedical Sciences researcher gets $1.6 million to develop anti-inflammatory drug
Dr. Jian-Dong Li, a professor and director of the Institute for Biomedical Sciences at Georgia State University and a Georgia Research Alliance Eminent Scholar in Inflammation and Immunity, has received a five-year, $1.6 million federal grant to develop novel anti-inflammatory therapeutics against middle-ear infections.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: LaTina Emerson
Georgia State University

Public Release: 1-Jul-2015
Cancer Cell
Experimental drug combined with standard chemo may shrink ovarian cancers
Working in cell cultures and mice, researchers at Johns Hopkins have found that an experimental drug called fostamatinib combined with the chemotherapy drug paclitaxel may overcome ovarian cancer cells' resistance to paclitaxel.
National Institutes of Health, Conquer Cancer Foundation, HERA Women's Cancer Foundation, Ovarian Cancer Research Fund

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 1-Jul-2015
JAMA Psychiatry
Trends in antipsychotic medication use in children, adolescents, and young adults
Despite concerns that use of antipsychotic medications in treating young people has increased, use actually declined between 2006 and 2010 for children ages 12 and under, and increased for adolescents and young adults.
National Institutes of Health

Contact: Rachel Yarmolinsky
Columbia University Medical Center

Public Release: 1-Jul-2015
Seeing is believing
Researchers have uncovered key principles about the way vision-neurons work, explaining how the brain uses sensory information to guide the decisions that drive behaviors.
Sackler Scholarship, Quan Fellowship, Natural Sciences and Engineering Research Council of Canada, NIH/National Eye Institute, Core Grant for Vision Research

Contact: David Cameron
Harvard Medical School

Public Release: 1-Jul-2015
Psychiatric Services
Virtual training helps vets with PTSD, mentally ill nab more jobs
Finding a job is difficult for veterans with PTSD and individuals with severe mental illness, who have high unemployment rates though many want to work. The job interview can be a major hurdle. A special training program using a virtual human -- originally used to train FBI agents -- helped vets with PTSD and individuals with severe mental illness build job interview skills and snag nine times more job offers, reports a new study.
National Institutes of Health

Contact: Marla Paul
Northwestern University

Public Release: 1-Jul-2015
Revised view of brain circuit reveals how we avoid being overwhelmed by powerful odors
Today in Neuron, scientists at CSHL report discovery of a neural circuit in the mouse olfactory bulb that explains how our mammalian cousins (and by extension, we) are able to dial down powerful odor signals sampled from the environment, for the simple reason that they would otherwise overpower the nerve cells that receive and process them.
NIH/National Institute on Deafness and Other Communication Disorders, European Molecular Biology Organization, Cold Spring Harbor Laboratory, Crick-Clay Fellowship, Farish-Gerry Fellowship

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 1-Jul-2015
Science Translational Medicine
Stanford study: Immune response to a flu protein yields new insights into narcolepsy
An international team of researchers has found some of the first solid evidence that narcolepsy may be a so-called 'hit-and-run' autoimmune disease.
NIH/National Center for Research Resources

Contact: Bruce Goldman
Stanford University Medical Center

Showing releases 1-25 out of 3754.

1 | 2 | 3 | 4 | 5 > >>


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