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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 1-25 out of 3470.

1 | 2 | 3 | 4 | 5 > >>

Public Release: 23-Sep-2014
Lab on a Chip
Airway muscle-on-a-chip mimics asthma
New drugs are urgently needed to treat asthma. Hope may be on the horizon thanks to a team that has developed a human airway muscle-on-a-chip that accurately mimics the way smooth muscle contracts in the human airway, under normal circumstances and when exposed to asthma triggers. As reported in the journal Lab on a Chip, it also offers a window into the cellular and even subcellular responses within the tissue during an asthmatic event.
National Institutes of Health, Harvard SEAS

Contact: Kristen Kusek
kristen.kusek@wyss.harvard.edu
617-432-8266
Wyss Institute for Biologically Inspired Engineering at Harvard

Public Release: 23-Sep-2014
Nature Communications
A multi-function protein is key to stopping genomic parasites from 'jumping'
Most organisms, including humans, have parasitic DNA fragments called 'jumping genes' that insert themselves into DNA molecules, disrupting genetic instructions in the process. And that phenomenon can result in age-related diseases such as cancer. But researchers at the University of Rochester now report that the 'jumping genes' in mice become active as the mice age when a multi-function protein stops keeping them in check in order to take on another role.
National Institutes of Health

Contact: Peter Iglinski
peter.iglinski@rochester.edu
585-273-4726
University of Rochester

Public Release: 23-Sep-2014
mBio
Critically ill ICU patients lose almost all of their gut microbes and the ones left aren't good
Researchers at the University of Chicago have shown that after a long stay in the Intensive Care Unit only a handful of pathogenic microbe species remain behind in patients' intestines. The team tested these remaining pathogens and discovered that some can become deadly when provoked by conditions that mimic the body's stress response to illness.
National Institutes of Health, US Department of Energy

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology

Public Release: 22-Sep-2014
Health Psychology
We drink more alcohol on gym days
A new Northwestern Medicine study finds that on days when people exercise more -- typically Thursdays to Sundays -- they drink more alcohol, too.
NIH/National Institute on Aging, NIH/National Institute on Drug Abuse

Contact: Erin White
ewhite@northwestern.edu
847-491-4888
Northwestern University

Public Release: 22-Sep-2014
Cell Reports
Massachusetts General study reveals gene expression patterns in pancreatic CTCs
Analysis of circulating tumor cells in a mouse model of pancreatic cancer identified distinct patterns of gene expression in several groups of CTCs, including significant differences from the primary tumor that may contribute to the ability to generate metastases. The Massachusetts General Hospital Cancer Center investigators identified several different classes of pancreatic CTCs and found unexpected factors that may prove to be targets for improved treatment of the deadly tumor.
Stand Up to Cancer, Howard Hughes Medical Institute, Burroughs Wellcome Fund, NIH/National Institute of Biomedical Imaging and Bioengineering, NIH/National Cancer Institute, Affymetrix, Inc.

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Public Release: 22-Sep-2014
Journal of Controlled Release
New chip promising for tumor-targeting research
Researchers have developed a chip capable of simulating a tumor's 'microenvironment' and plan to use the new system to test the effectiveness of nanoparticles and drugs that target cancer.
National Science Foundation, National Institutes of Health

Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Genetic switch regulates a plant's internal clock based on temperature
Scientists have found the molecular cog in a plant's biological clock that modulates its speed based on temperature.
The Ruth L. Kirschstein National Research Service Award, National Instiutes of Health, NIH/National Institute of General Medical Sciences

Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California

Public Release: 22-Sep-2014
Rutgers receives $2 million grant to prepare biomedical students for roles in industry
Rutgers' School of Engineering and Rutgers Graduate School of Biomedical Sciences are joint recipients of a $2 million 2014 BEST grant from the National Institutes of Health. Once upon a time, students seeking advanced degrees in the biomedical sciences generally expected to find careers in academia, and their mentors expected them to do so. No longer. Fewer than half of those students now end up in academia. So the National Institutes of Health created the BEST grant, aimed at preparing students for potential careers in industry and other non-academic areas.
National Institutes of Health

Contact: Rob Forman
robert.forman@rutgers.edu
973-972-7276
Rutgers University

Public Release: 22-Sep-2014
Behavioral Brain Research
Compound from hops aids cognitive function in young animals
Xanthohumol, a type of flavonoid found in hops and beer, has been shown in a new study to improve cognitive function in young mice, but not in older animals. The findings are another step toward understanding, and ultimately reducing the degradation of memory that happens with age in many mammalian species, including humans.
National Institutes of Health

Contact: Kathy Magnusson
Kathy.magnusson@oregonstate.edu
541-737-6923
Oregon State University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Variability keeps the body in balance
Although the heart beats out a very familiar 'lub-dub' pattern that speeds up or slows down as our activity increases or decreases, the pattern itself isn't as regular as you might think. In fact, the amount of time between heartbeats can vary even at a 'constant' heart rate -- and that variability, doctors have found, is a good thing.
John G. Braun Professorship, Air Force Office of Scientific Research, National Science Foundation, Pfizer, National Institutes of Health, Institute of Collaborative Biotechnologies

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Public Release: 22-Sep-2014
Brain, Behavior and Immunity
Obesity and stress pack a double hit for health
If you're overweight, you may be at greater risk for stress-related diseases like type 2 diabetes, cardiovascular disease and cancer, according to a new study by Brandeis University. In a recently published paper in Brain, Behavior and Immunity, Brandeis researchers observed that overweight and obese individuals have higher levels of stress-induced inflammation than those within a healthy weight-range.
American Federation of Aging Research, National Institutes of Health

Contact: Leah Burrows
lburrows@brandeis.edu
781-736-4027
Brandeis University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Platelets modulate clotting behavior by 'feeling' their surroundings
Platelets respond to surfaces with greater stiffness by increasing their stickiness, the degree to which they "turn on" other platelets and other components of the clotting system, Emory and Georgia Tech researchers found.
National Science Foundation, American Heart Association, NIH/National Heart Lung Blood Institute, NIH/National Eye Institute

Contact: Quinn Eastman
qeastma@emory.edu
404-727-7829
Emory Health Sciences

Public Release: 22-Sep-2014
Mammalian Genome
Lack of thyroid hormone blocks hearing development
Fatigue, weight gain, chills, hair loss, anxiety, excessive perspiration -- these symptoms are a few of the signs that the thyroid gland has gone haywire. Harnessing electron microscopy to track the inner hair cells of the cochlea in two groups of mice, new research from Tel Aviv University points to an additional complication caused by an imbalance in the thyroid gland: congenital deafness.
National Institutes of Health, I-CORE Gene Regulation in Complex Human Disease

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Lego-like modular components make building 3-D 'labs-on-a-chip' a snap
Thanks to new Lego-like components developed by researchers at the University of Southern California Viterbi School of Engineering, it is now possible to build a 3-D microfluidic system (or 'lab-on-a-chip') quickly and cheaply by simply snapping together small modules by hand.
National Institutes of Health

Contact: Megan Hazle
hazle@usc.edu
213-821-1887
University of Southern California

Public Release: 22-Sep-2014
JAMA Pediatrics
Cytomegalovirus linked to maternal breast milk in very-low-birth-weight infants
The primary source of postnatal infection with cytomagelovirus, a common virus usually without symptoms in very-low-birth-weight infants appeared to be maternal breast milk because no infections were linked to transfusions of cytomagelovirus-seronegative and leukoreduced blood products.
NIH/National Heart, Lung and Blood Institute

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
The JAMA Network Journals

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
The fine line between breast cancer and normal tissues
Researchers at Brigham and Women's Hospital have successfully tested a tool they developed that will help surgeons better distinguish cancerous breast tissue from normal tissue, thereby decreasing the chances for repeat operations.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-525-6383
Brigham and Women's Hospital

Public Release: 22-Sep-2014
Journal of Experimental Medicine
New rules for anticancer vaccines
Scientists have found a way to find the proverbial needle in the cancer antigen haystack. The results have the potential to completely change current approaches to generating anticancer vaccines.
Cancer Research Institute NY, Northeastern Utilities, Connecticut Institute for Clinical and Translational Science, SPARK, National Science Foundation, National Institutes of Health, Life Technologies, USDA/National Institute of Food and Agriculture

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Public Release: 22-Sep-2014
Journal of Autism and Developmental Disorders
Brainwave test could improve autism diagnosis and classification
A new study by researchers at Albert Einstein College of Medicine of Yeshiva University suggests that measuring how fast the brain responds to sights and sounds could help in objectively classifying people on the autism spectrum and may help diagnose the condition earlier. The paper was published today in the online edition of the Journal of Autism and Developmental Disabilities.
NIH/National Institute of Mental Health

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine

Public Release: 22-Sep-2014
American Journal of Epidemiology
Mothers of children with autism less likely to have taken iron supplements
Mothers of children with autism are significantly less likely to report taking iron supplements before and during their pregnancies than the mothers of children who are developing normally, a study by researchers with the UC Davis MIND Institute has found.
National Institutes of Health, US Environmental Protection Agency Science to Achieve Results

Contact: Phyllis Brown
phyllis.brown@ucdmc.ucdavis.edu
916-734-9023
University of California - Davis Health System

Public Release: 21-Sep-2014
Nature Nanotechnology
Engineered proteins stick like glue -- even in water
MIT researchers find new adhesives based on mussel proteins could be useful for naval or medical applications.
Office of Naval Research, National Science Foundation, National Institutes of Health

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Public Release: 21-Sep-2014
Nature Biotechnology
Battling superbugs
Two new technologies from researchers at MIT could enable novel strategies for combating drug-resistant bacteria.
National Institutes of Health, Defense Threat Reduction Agency, US Army Research Laboratory, US Army Research Office, Office of Naval Research, The Ellison Foundation

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Public Release: 21-Sep-2014
Journal of Allergy & Clinical Immunology
Dry roasting could help trigger peanut allergy
Dry roasted peanuts are more likely to trigger an allergy to peanuts than raw peanuts, suggests an Oxford University study involving mice. The researchers say that specific chemical changes caused by the high temperatures of the dry roasting process are recognized by the body's immune system, 'priming' the body to set off an allergic immune response the next time it sees any peanuts.
NIH/National Institute for Health Research, Oxford Biomedical Research Centre, National Institutes of Health, Swiss National Science Foundation

Contact: University of Oxford News & Information Office
news.office@admin.ox.ac.uk
44-186-528-0530
University of Oxford

Public Release: 21-Sep-2014
Nature Methods
Program predicts placement of chemical tags that control gene activity
Biochemists have developed a program that predicts the placement of chemical marks that control the activity of genes based on sequences of DNA. By comparing sequences with and without epigenomic modification, they identified DNA motifs associated with the changes. They call this novel analysis pipeline Epigram and have made both the program and the DNA motifs they identified openly available to other scientists.
NIH/National Institute of Environmental Health Sciences

Contact: Susan Brown
scinews@ucsd.edu
858-246-0161
University of California - San Diego

Public Release: 20-Sep-2014
Development
University of Southern California researchers reveal how gene expression affects facial expressions
A person's face is the first thing that others see, and much remains unknown about how it forms -- or malforms -- during early development. Recently, Chong Pyo Choe, a senior postdoctoral fellow working in the lab of University of Southern California stem cell researcher Gage Crump, has begun to unwind these mysteries.
NIH/National Institute of Dental and Craniofacial Research, California Institute for Regenerative Medicine

Contact: Cristy Lytal
lytal@med.usc.edu
323-442-2172
University of Southern California - Health Sciences

Public Release: 19-Sep-2014
Genes & Development
Scientists discover an on-off switch for aging cells
Scientists at the Salk Institute have discovered an on-and-off 'switch' in cells that may hold the key to healthy aging. This switch points to a way to encourage healthy cells to keep dividing and generating, for example, new lung or liver tissue, even in old age.
National Institutes of Health, Fritz B. Burns Foundation, Rose Hills Foundation

Contact: Salk Communications
press@salk.edu
Salk Institute

Showing releases 1-25 out of 3470.

1 | 2 | 3 | 4 | 5 > >>

     
   

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