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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 1-25 out of 3612.

1 | 2 | 3 | 4 | 5 > >>

Public Release: 1-Apr-2015
Nature
Study affirms lethal prostate cancer can spread from other metastatic sites
A new genomic analysis of tissue from patients with prostate cancer has added more evidence that cells within metastases from such tumors can migrate to other body parts and form new sites of spread on their own.
Cancer Research UK, Academy of Finland, Cancer Society of Finland, PELICAN Autopsy Study, Johns Hopkins Brady Urological Institute, John and Kathe Dyson, NIH/National Cancer Institute

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 1-Apr-2015
PLOS Neglected Tropical Diseases
New class of insecticides offers safer, more targeted mosquito control
Purdue researchers have identified a new class of chemical insecticides that could provide a safer, more selective means of controlling mosquitoes that transmit key infectious diseases such as dengue, yellow fever and elephantiasis.
US Department of Defense, Purdue Research Foundation, Indiana Clinical and Translational Sciences Institute, NIH/National Center for Advancing Translational Science

Contact: Natalie van Hoose
nvanhoos@purdue.edu
765-496-2050
Purdue University

Public Release: 1-Apr-2015
Science Signaling
Penn Medicine: New receptors could underlie the many actions of the anesthetic ketamine
Penn Medicine researchers are continuing their work in trying to understand the mechanisms through which anesthetics work to elicit the response that puts millions of Americans to sleep for surgeries each day. Their most recent study looked at ketamine, an anesthetic discovered in the 1960s and recently prescribed as an anti-depressant at low doses. Researchers have identified an entirely new class of receptors that ketamine binds in the body, which may underlie its diverse actions.
National Institutes of Health, Penn Nano/Bio Interface Center

Contact: Lee-Ann Donegan
leeann.donegan@uphs.upenn.edu
215-349-5660
University of Pennsylvania School of Medicine

Public Release: 1-Apr-2015
ACS Nano
A novel way to apply drugs to dental plaque
Therapeutic agents intended to reduce dental plaque and prevent tooth decay are often removed by saliva and the act of swallowing before they take effect. But a team of researchers has developed a way to keep the drugs from being washed away.
National Science Foundation, National Institutes of Health

Contact: Peter Iglinski
peter.iglinski@rochester.edu
585-273-4726
University of Rochester

Public Release: 1-Apr-2015
Journal of Neuroscience
How we hear distance: Echoes are essential for humans to perceive how far away a sound is
Mammals are good at figuring out which direction a sound is coming from, whether it's a predator breathing down our necks or a baby crying for its mother. But how we judge how far away that sound is was a mystery until now. Researchers from UConn Health report in the April 1 issue of the Journal of Neuroscience that echoes and fluctuations in volume are the cues we use to figure the distance between us and the source of a noise. 
National Institutes of Health

Contact: Kim Krieger
kim.krieger@uconn.edu
860-486-0361
University of Connecticut

Public Release: 1-Apr-2015
Spine
Predicting chronic pain in whiplash injuries
While most people recover from whiplash injuries within a few months, about 25 percent have long-term pain and disability for many months or years. Using special MRI imaging, scientists identified, within the first one and two weeks of the injury, which patients will develop chronic pain and disability. This is the earliest these patients have been identified and will enable faster treatment. The imaging revealed large amounts of fat infiltrating the patients' neck muscles, indicating rapid atrophy.
National Institutes of Health

Contact: Marla Paul
marla-paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 1-Apr-2015
New England Journal of Medicine
VSV-EBOV Ebola vaccine appears safe and generates immune response
An experimental Ebola vaccine called VSV-EBOV appears safe and elicited a robust immune response in a small phase 1 clinical trial, according to findings to be published in the New England Journal of Medicine on April 2, 2015. Two independent but coordinated studies, performed at the Walter Reed Army Institute of Research and the National Institute of Allergy and Infectious Diseases, explored the safety and immunogenicity of the investigational vaccine when administered at different dosages.
NIH/National Institute of Allergy and Infectious Diseases, NIH/National Cancer Institute,Defense Threat Reduction Agency, Joint Vaccine Acquisition Program

Contact: Dr. Debra Yourick
debra.l.yourick.civ@mail.mil
301-319-9471
US Army Medical Research Institute of Infectious Diseases

Public Release: 1-Apr-2015
PLOS Pathogens
Anticancer drug can spur immune system to fight infection
Imatinib, an example of a 'targeted therapy' against cancer, or related drugs might be tools to fight a variety of infections.
NIH/National Institute of Allergy and Infectious Diseases, NIH/National Heart, Lung, and Blood Institute

Contact: Quinn Eastman
qeastma@emory.edu
404-727-7829
Emory Health Sciences

Public Release: 1-Apr-2015
Nature
Exercise for older mouse mothers lowers risk of heart defects in babies
In people, a baby's risk of congenital heart defects is associated with the age of the mother. Risk goes up with increasing age. Newborn mice predisposed to heart defects because of genetic mutations show the same age association. A new study demonstrates that older mouse mothers reduce this risk for their offspring to that of younger mouse mothers through exercise alone, according to researchers at Washington University School of Medicine in St. Louis.
National Institutes of Health, American Heart Association, Lawrence J. & Florence A. DeGeorge Charitable Trust, Children's Discovery Institute of Washington University and St. Louis Children's Hospital, Children's Heart Foundation

Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine

Public Release: 1-Apr-2015
JAMA Dermatology
Sexual dysfunction inadequately reported in hair loss drug trials
Not one of the 34 published clinical trial reports provided adequate information about the severity, frequency or reversibility of sexual adverse effects.
National Institutes of Health, Post-Finasteride Syndrome Foundation

Contact: Marla Paul
Marla-Paul@Northwestern.edu
Northwestern University

Public Release: 1-Apr-2015
Nature
Springing ahead of nature: Device increases walking efficiency
It's taken millions of years for humans to perfect the art of walking. But research results published today in the journal Nature show that humans can get better 'gas mileage' using an unpowered exoskeleton to modify the structure of their ankles. The device puts an extra spring in each human step, reducing metabolic energy consumption by 7 percent below walking in normal athletic shoes.
U.S.-Israel Binational Science Foundation, NIH/National Institute of Nursing Research, National Science Foundation

Contact: Dr. Greg Sawicki
greg_sawicki@ncsu.edu
North Carolina State University

Public Release: 1-Apr-2015
Cancer Epidemiology, Biomarkers & Prevention
Number of childhood cancer survivors increasing, most have morbidities
The prevalence of childhood cancer survivors is estimated to have increased, and the majority of those who have survived five or more years beyond diagnosis may have at least one chronic health condition.
National Institutes of Health

Contact: Lauren Riley
lauren.riley@aacr.org
215-446-7155
American Association for Cancer Research

Public Release: 31-Mar-2015
Nature Medicine
Researchers identify 'beige' fat-burning cells in humans
For the first time, a research team, led by a UC San Francisco biologist, has isolated energy-burning 'beige' fat from adult humans, which is known to be able to convert unhealthy white fat into healthy brown fat. The scientists also found new genetic markers of this beige fat.
National Institutes of Health, Pew Charitable Trust, Japan Science and Technology Agency, Japan Society for the Promotion of Science, Manpei Suzuki Diabetes Foundation

Contact: Pete Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 31-Mar-2015
Clinical Science
Folic acid may help elderly weather heat waves
Supplemental folic acid can enhance blood vessel dilation in older adults, according to Penn State researchers, suggesting that folic acid supplements may be an inexpensive alternative for helping older adults to increase skin blood flow during heat waves and reduce cardiovascular events.
National Institutes of Health

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State

Public Release: 31-Mar-2015
Proceedings of the National Academy of Sciences
Premature aging of stem cell telomeres, not inflammation, linked to emphysema
Lung diseases like emphysema and pulmonary fibrosis are common among people with malfunctioning telomeres, the 'caps' or ends of chromosomes. Now, researchers from Johns Hopkins say they have discovered what goes wrong and why.
National Institutes of Health, Ellison Medical Foundation, Flight Attendant Medical Research Institute

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 31-Mar-2015
$2.1 million grant targets antibiotic resistance
Dr. Walter Fast at The University of Texas at Austin has received a four-year $2.1 million grant to develop small-molecules that counter antibiotic resistance in Gram-negative bacteria. If successful, the research focusing on enzymes called metallo-beta-lactamases could lead to new drugs for treating bacterial infections resistant to antibiotics.
National Institutes of Health

Contact: Vicki Matustik
vicki.matustik@austin.utexas.edu
512-232-1769
University of Texas at Austin

Public Release: 31-Mar-2015
Orthopaedic Research Society 2015 Annual Meeting
Brittle bone disease: Drug research offers hope
New research at the University of Michigan offers evidence that a drug being developed to treat osteoporosis may also be useful for treating osteogenesis imperfecta or brittle bone disease, a rare but potentially debilitating bone disorder that that is present from birth.
National Institutes of Health

Contact: Gabe Cherry
gcherry@umich.edu
734-647-7085
University of Michigan

Public Release: 31-Mar-2015
PLOS ONE
Score! Video gamers may learn visual tasks more quickly
Video games not only sharpen the visual processing skills of frequent players, they might also improve the brain's ability to learn those skills, according to a new study. Gamers showed faster consolidation of learning when moving from one visual task to the next than did non-gamers.
National Institutes of Health

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 31-Mar-2015
Nature Communications
Scientists reveal unique mechanism of natural product with powerful antimicrobial action
Scientists from the Florida campus of The Scripps Research Institute have uncovered the unique mechanism of a powerful natural product with wide-ranging antifungal, antibacterial, anti-malaria and anti-cancer effects. The new study sheds light on the natural small molecule known as borrelidin.
National Institutes of Health, Korean Global Frontier Project, and PGA Women's Cancer Awareness Foundation

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 31-Mar-2015
Journal of Studies on Alcohol and Drugs
Kids allowed to 'sip' alcohol may start drinking earlier
Children who get a taste of their parents' wine now and then may be more likely than their peers to start drinking by high school, according to a new report in the Journal of Studies on Alcohol and Drugs.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Journal of Studies on Alcohol and Drugs

Public Release: 30-Mar-2015
Clinical Journal of Pain
UF study finds vitamin D can affect pain, movement in obese osteoarthritis patients
If you are overweight and have osteoarthritis, you may want to bone up on vitamin D.
NIH//National Institute on Aging, University of Florida Clinical and Translational Science Institute

Contact: Tracy Wright
tracyb@ufl.edu
352-273-6421
University of Florida

Public Release: 30-Mar-2015
Proceedings of the National Academy of Sciences
3-D human skin maps aid study of relationships between molecules, microbes and environment
Researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences produced 3-D maps of molecular and microbial variations across the body. These maps provide a baseline for studies of the interplay between the molecules that make up our skin, our microbiomes, our personal hygiene routines and other environmental factors. The study, published March 30 by PNAS, may help further our understanding of the skin's role in human health and disease.
National Institutes of Health, Howard Hughes Medical Institute, Keck Foundation, San Diego Center for Systems Biology, European Union 7th Framework Programme and Science Without Borders Program

Contact: Heather Buschman
hbuschman@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 30-Mar-2015
OU team receives grant for innovative technique to enhance breast cancer detection
An innovative technique that enhances breast cancer detection while reducing radiation dose has been proposed by a University of Oklahoma research team. In response, the National Cancer Institute of the National Institutes of Health has awarded a $3 million grant to the OU team to facilitate the technique, which includes building a patient imaging system and conducting preclinical evaluations and Phase I clinical trials.
NIH/National Cancer Institute

Contact: Jana Smith
jana.smith@ou.edu
405-325-1322
University of Oklahoma

Public Release: 30-Mar-2015
Depression and Anxiety
Impact of domestic violence on women's mental health
In addition to their physical injuries, women who are victims of domestic violence are also at a greater risk of mental health problems such as depression and psychotic symptoms.
United Kingdom Medical Research Council, Economic and Social Research Council, NIh/National Institute of Child Health and Human Development, NIH/National Institute of Mental Health

Contact: William Raillant-Clark
w.raillant-clark@umontreal.ca
514-343-7593
University of Montreal

Public Release: 30-Mar-2015
Annals of Internal Medicine
BMC study: New Hepatitis C treatments cost-effective, but only for selected patients
A study led by Boston Medical Center researchers demonstrates that while new therapies to treat Hepatitis C Virus are highly effective, they are cost-effective and provide the greatest value in specific groups of HCV-infected patients.
NIH/National Institute on Drug Abuse, NIH/National Institute of Allergy and Infectious Disease

Contact: Elissa Snook
elissa.snook@bmc.org
617-638-6823
Boston University Medical Center

Showing releases 1-25 out of 3612.

1 | 2 | 3 | 4 | 5 > >>

     
   

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