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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 1-25 out of 3685.

1 | 2 | 3 | 4 | 5 > >>

Public Release: 25-Nov-2015
Proceedings of the National Academy of Sciences
Closing the loop on an HIV escape mechanism
A collaborative six-university research team finds that the motion of a specific protein in a human cell regulates whether HIV will infect other cells. The finding may lead to promising new ways to thwart the virus that causes AIDS.
National Institutes of Health, National Science Foundation

Contact: Peter Bothum
University of Delaware

Public Release: 25-Nov-2015
Scientific Data
Data scientists create world's first therapeutic venom database
What doesn't kill you could cure you. A growing interest in the therapeutic value of animal venom has led a pair of Columbia University data scientists to create the first catalog of known animal toxins and their physiological effects on humans.
National Library of Medicine, NIH/National Institute of General Medical Sciences

Contact: Lucky Tran, Ph.D.
Columbia University Medical Center

Public Release: 25-Nov-2015
Proceedings of the National Academy of Sciences
Peering into cell structures where neurodiseases emerge
In the Proceedings of the National Academy of Sciences, a Univeristy of Delaware-led research team reveals for the first time -- atom by atom -- the structure of CAP-Gly, a protein that binds to the latticework of microtubules in your cells. When mutations occur in CAP-Gly, neurological diseases and disorders occur, including Perry syndrome and distal spinal bulbar muscular dystrophy.
National Institutes of Health, NIH/National Institute of General Medical Sciences, National Science Foundation

Contact: Peter Bothum
University of Delaware

Public Release: 25-Nov-2015
JAHA: Journal of the American Heart Association
Air pollution and cardiovascular disease: Increased risk for women with diabetes
Air pollution is a major risk factor for cardiovascular disease, and some people may be more susceptible to its effects than others. Investigators from Brigham and Women's Hospital and Harvard T. H. Chan School of Public Health used data from a nationwide study of nurses to look for factors that made people more vulnerable to the effects of long-term air pollution exposure. One factor in particular stood out to the researchers: type 2 diabetes.
National Institutes of Health, American Heart Association Science

Contact: Haley Bridger
Brigham and Women's Hospital

Public Release: 25-Nov-2015
New technology promises fast, accurate stroke diagnosis
A new approach to identifying biomarkers in blood has proven successful in helping diagnose stroke, and the technology could be expanded to diagnose such conditions as concussion, some forms of dementia, and some types of cancer and heart disease.
New York State Centers for Advanced Technology, State University of New York Health Research Foundation, National Institutes of Health Pioneer Award

Contact: Merry Buckley
Cornell University, College of Veterinary Medicine

Public Release: 25-Nov-2015
MECP2 duplication syndrome is reversible
Research led by Huda Zoghbi, M.D., at Baylor College of Medicine and HHMI and published today in the journal Nature reveals that the MECP2 Duplication Syndrome is reversible. Importantly the study paves the way for treating duplication patients with an antisense oligonucleotide strategy.
Rett Syndrome Research Trust, National Institutes of Health, Carl C. Anderson, Sr. and Marie Jo Anderson Charitable Foundation, Howard Hughes Medical Institute, National Science Foundation, Baylor Intellectual Disabilities Research Center

Contact: Monica Coenraads
Rett Syndrome Research Trust

Public Release: 25-Nov-2015
Current Biology
At the edge of vision: Struggling to make sense of our cluttered world
Even with 20/20 vision in broad daylight on a clear day, our peripheral vision can be surprisingly poor, particularly when the scene in front of us is cluttered. Now, scientists at the University of Cambridge, UK, Northeastern University, Boston, USA, and Queensland Brain Institute, Brisbane, Australia, believe they are a step closer to understanding why this is.
National Institutes of Health, National Health and Medical Research Council of Australia

Contact: Craig Brierley
University of Cambridge

Public Release: 25-Nov-2015
Cell Reports
How cells 'climb' to build fruit fly tracheas
Fruit fly windpipes are much more like human blood vessels than the entryway to human lungs. To create that intricate network, fly embryonic cells must sprout 'fingers' and crawl into place. Now researchers at The Johns Hopkins University have discovered that a protein called Mipp1 is key to cells' ability to grow these fingers.
NIH/National Institute of Dental and Craniofacial Research

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 25-Nov-2015
How cells in the developing ear 'practice' hearing
Before the fluid of the middle ear drains and sound waves penetrate for the first time, the inner ear cells of newborn rodents practice for their big debut. Researchers at Johns Hopkins report they have figured out the molecular chain of events that enables the cells to make 'sounds' on their own, essentially 'practicing' their ability to process sounds in the world around them.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of Mental Health, NIH/National Institute on Deafness and other Communication Disorders, NIH/National Institute of General Medical Sciences

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 25-Nov-2015
JAHA: Journal of the American Heart Association
Women with diabetes exposed to air pollution at higher risk for heart disease
Women with diabetes who are exposed to air pollution for long periods may have a much higher risk for heart disease.
National Institutes of Health and American Heart Association

Contact: Karen Astle
American Heart Association

Public Release: 25-Nov-2015
Cell Metabolism
Dietary restriction gives fruit flies a rhythm for a long life
Dietary restriction enhances the expression of the circadian clock genes in the peripheral tissue of fruit flies. Researchers at the Buck Institute show that dietary restriction, induced by reducing protein in the diet, increased the amplitude of circadian clocks and enhanced the cycles of fat breakdown and fat synthesis. This improvement in fat metabolism may be a key mechanism in explaining why dietary restriction extends lifespan in several species, including the flies in this study.
American Federation of Aging Research, Larry L. Hillblom Foundation, National Institutes of Health, Ellison Medical Foundation

Contact: Kris Rebillot
Buck Institute for Research on Aging

Public Release: 24-Nov-2015
Nature Immunology
Researchers discover how immune cells resist radiation treatment
Researchers at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai have discovered a key mechanism by which radiation treatment (radiotherapy) fails to completely destroy tumors. And, in the journal Nature Immunology, they offer a novel solution to promote successful radiotherapy for the millions of cancer patients who are treated with it.
National Institutes of Health, American Medical Association, NIH/National Institute of Arthritis Musculoskeletal and Skin Diseases, NIH/National Cancer Institute

Contact: Lucia Lee
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 24-Nov-2015
Molecular Neuropsychiatry
Neurological underpinnings of schizophrenia just as complex as the disorder itself
Schizophrenia is notoriously difficult to diagnose and treat, in large part because it manifests differently in different people. A new study helps explain why. Researchers at UNC have created a map that shows how specific schizophrenia symptoms are linked to distinct brain circuits.
National Institutes of Health

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 24-Nov-2015
Angewandte Chemie International Edition
Chemical design made easier
Rice University scientists have developed a metal-free process for the rapid synthesis of elusive small-molecule catalysts that promise to speed the making of novel chemicals, including drugs.
Rice University, National Institutes of Health, National Science Foundation, Robert A. Welch Foundation, Amgen

Contact: David Ruth
Rice University

Public Release: 24-Nov-2015
A heavy metal balancing act: Studying copper to help cells battle bacterial invaders
Copper is an essential micronutrient, but unless it is bound to proteins, it is also toxic to cells. With a $1.3 million award from the National Institutes of Health, researchers at Worcester Polytechnic Institute will conduct a systematic study of copper in the bacteria Pseudomonas aeruginosa, a leading cause of hospital-associated infections, with the hope of discovering new drug targets that might allow cells in the body to use copper to battle bacterial invaders.
National Institutes of Health

Contact: Michael Cohen
Worcester Polytechnic Institute

Public Release: 24-Nov-2015
Reducing body temperature saves neurological functions in cardiac arrest patients
Survivors of cardiac arrest who remain in comas have better survival and neurological outcomes when their body temperatures are lowered, according to new research by Dr. Sarah Perman at the University of Colorado Anschutz Medical Campus.
National Institutes of Health

Contact: David Kelly
University of Colorado Anschutz Medical Campus

Public Release: 24-Nov-2015
American Journal of Epidemiology
PMS as an early marker for future high blood pressure risk
In the first prospective study to consider premenstrual syndrome (PMS) as a possible sentinel for future risk of hypertension, epidemiologist Elizabeth Bertone-Johnson and colleagues in the School of Public Health and Health Sciences at the University of Massachusetts Amherst and the Harvard School of Public Health report that women with moderate-to-severe PMS had a 40 percent higher risk of developing high blood pressure over the following 20 years compared to women experiencing few menstrual symptoms.
NIH's Office for Research on Women's Health, NIH/National Heart, Lung, and Blood Institute, NIH/National Cancer Institute

Contact: Janet Lathrop
University of Massachusetts at Amherst

Public Release: 24-Nov-2015
Scientific Reports
Virginia Tech's Verbridge and Davalos describe novel tumor treatment in Scientific Reports
In the first published results from a $386,000 National Cancer Institute grant awarded earlier this year, a paper by Scott Verbridge and Rafael Davalos in Scientific Reports has been published, describing the researchers' work on developing a new type of treatment for glioblastoma multiforme, the most common and deadly malignant primary brain tumor.
NIH/National Cancer Institute

Contact: Lynn Nystrom
Virginia Tech

Public Release: 23-Nov-2015
Journal of Biological Chemistry
Infertile worms resist infection-induced neurodegeneration
Mounting evidence points to a link between infections, the immune response, and neurodegenerative diseases. New findings from Duke appearing in the Journal of Biological Chemistry show that infection with pathogenic bacteria causes neurodegeneration in the worm C. elegans, creating neural changes that are hallmarks of illnesses like Alzheimer's disease in humans. The study also yielded a big surprise: sterile animals appeared to be protected from neurodegeneration.
National Institutes of Health

Contact: Karl Bates
Duke University

Public Release: 23-Nov-2015
BMC Systems Biology
Tuberculosis: Daily antibiotics recommended to prevent resistant strains
A computer model of tuberculosis has shown that approved treatments prescribing antibiotic doses once or twice a week are more likely to lead to drug resistant strains than are daily antibiotic regimens.
National Institutes of Health, National Energy Research Computing Center, Open Science Grid, Extreme Science and Engineering Discovery Environment

Contact: Katherine McAlpine
University of Michigan

Public Release: 23-Nov-2015
Scientific Reports
Stem cell treatment mediates immune response to spinal cord injury in pre-clinical trials
Scientists at Case Western Reserve University School of Medicine have demonstrated in lab animals that a family of therapeutic stem cells called multipotent adult progenitor cells lessen the consequences of the immune system's damaging second wave response and preserve function that would otherwise be lost. Their findings appear in the Nov. 19 edition of Scientific Reports, an online journal from the publishers of the journal Nature.
Ohio Third Frontier Grant, NIH/National Institute of Neurological Disorders and Stroke, CWRU Council to Advance Human Health, Unite to Fight Paralysis, Spinal Cord Injury Sucks, United Paralysis Foundation

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 23-Nov-2015
Proceedings of the National Academy of Sciences
Researchers identify genes connecting endocrine disruption to genital malformations
University of Florida Health researchers have identified genes that are disrupted by abnormal hormone signaling at crucial points during development, a finding that may lead to a better understanding of how the most common male genital birth defects arise in humans.
National Institutes of Health

Contact: Doug Bennett
University of Florida

Public Release: 23-Nov-2015
Plant Cell
Penn biologists characterize new form of mRNA regulation
In a new report in the journal Plant Cell, University of Pennsylvania biologists used material from both humans and plants to examine chemical modifications to messenger RNA, or mRNA, finding that the modifications appear to play a significant role in the process by which mRNAs either survive and become translated into protein or are targeted for degradation.
National Science Foundation, NIH/National Institute of General Medical Sciences

Contact: Katherine Unger Baillie
University of Pennsylvania

Public Release: 23-Nov-2015
American Journal of Respiratory and Critical Care Medicine
Vitamin D does not reduce colds in asthma patients
Vitamin D supplements do not reduce the number or severity of colds in asthma patients, according to a new study published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.
NIH/National Heart, Lung, and Blood Institute

Contact: Rory Williams
American Thoracic Society

Public Release: 23-Nov-2015
New test may improve diagnosis and treatment of pancreatic cancers
Collecting blood samples from the portal vein can provide much more information about pancreatic cancer than taking blood from vein in the arm. Researchers found circulating tumors cells in 100 percent of 18 patients with suspected tumors in the pancreas and bile ducts. Standard samples detected tumors cells in only four patients.
National Institutes of Health, Rolfe Pancreatic Cancer Foundation, Harriet and Allan Wulfstat, Gerald O. Mann Charitable Foundation, LLK (Live Like Katie) Cholangiocarcinoma Foundation

Contact: John Easton
University of Chicago Medical Center

Showing releases 1-25 out of 3685.

1 | 2 | 3 | 4 | 5 > >>


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