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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 1-25 out of 3777.

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Public Release: 2-Sep-2015
Reward, aversion behaviors activated through same brain pathways
New research at Washington University School of Medicine in St. Louis may help explain why drug treatments for addiction and depression don't work for some patients. The conditions are linked to reward and aversion responses in the brain. And the research suggests that some treatments simultaneously stimulate reward and aversion responses, resulting in a net zero effect.
NIH/National Institute on Drug Abuse, NIH/National Institute on Neurological Disorders and Stroke NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Jim Dryden
Washington University School of Medicine

Public Release: 2-Sep-2015
Psychological Science
Who gets a transplant organ
A Rutgers study examines how decisions are made when it comes to allocating scare resources. Imagine 12 patients who need new kidneys, and six kidneys available. How would you allocate them? New research by Rutgers social psychologists suggests your answer would depend on how the patients and their situations are presented to you.
NIH/National Institute on Aging

Contact: Ken Branson
Rutgers University

Public Release: 2-Sep-2015
Researchers identify a new approach for lowering harmful lipids
Xian-Cheng Jiang, Ph.D., professor of cell biology at SUNY Downstate Medical Center, has led a study identifying a new approach for lowering 'bad' lipids in blood circulation, a critical means to combat devastating cardiovascular diseases such as atherosclerosis.
US Department of Veterans Affairs, National Institutes of Health, American Heart Assocation

Contact: Ron Najman
SUNY Downstate Medical Center

Public Release: 2-Sep-2015
Journal of Neuroscience
Texas A&M team finds neuron responsible for alcoholism
Scientists have pinpointed a population of neurons in the brain that influences whether one drink leads to two, which could ultimately lead to a cure for alcoholism and other addictions. A study, published in the Journal of Neuroscience by researchers at the Texas A&M Health Science Center College of Medicine, finds that alcohol consumption alters the structure and function of neurons in the dorsomedial striatum, a part of the brain known to be important in goal-driven behaviors
NIH/National Institute on Alcohol Abuse and Alcoholism, 2014 John P. McGovern Award from the Texas Research Society on Alcoholism

Contact: Holly Shive
Texas A&M University

Public Release: 2-Sep-2015
Journal of Hepatology
WSU scientists discover mechanism for air pollution-induced liver disease
A research team led by Kezhong Zhang, Ph.D., at the Wayne State University School of Medicine's Center for Molecular Medicine and Genetics, has discovered that exposure to air pollution has a direct adverse health effect on the liver and causes liver fibrosis, an illness associated with metabolic disease and liver cancer.
NIH/National Environmental Health Science Institute, NIH/National Institute of Diabetes and Digestive and Kidney Disease, American Heart Association

Contact: Julie O'Connor
Wayne State University - Office of the Vice President for Research

Public Release: 2-Sep-2015
Proceedings of the National Academy of Sciences
Columbia Engineering team develops targeted drug delivery to lung
Researchers from Columbia Engineering and Columbia University Medical Center have developed a new method that can target delivery of very small volumes of drugs into the lung. Their approach, in which micro-liters of liquid containing a drug are instilled into the lung, distributed as a thin film in the predetermined region of the lung airway, and absorbed locally, may provide much more effective treatment of lung disease.
National Institutes of Health, Raymond and Beverly Sackler Foundation, Mikati Family Fund for Translational Research in Biomedical Engineering

Contact: Holly Evarts
Columbia University School of Engineering and Applied Science

Public Release: 2-Sep-2015
American Journal of Pathology
Newly discovered protein may protect kidney cells from injury
A new discovery by Boston University School of Medicine (BUSM) researchers may change how kidney disease is treated in the future. The previously unknown protein transmembrane and immunoglobulin containing 1 (TMIGD1) involved in protecting kidney epithelial cells (cells critical to normal kidney function) from injury, could be a novel target for restoring kidney function from various forms of kidney disease. The findings are published online in the American Journal of Pathology.
National Institutes of Health

Contact: Kristen Perfetuo
Boston University Medical Center

Public Release: 2-Sep-2015
New symptom may help ID sleep apnea in older women
Obstructive sleep apnea may be underdiagnosed in postmenopausal women. A new study strongly associates the condition's traditional risk factors with nocturnal enuresis (bedwetting), suggesting that it may be an additional screening factor for doctors to consider.
National Institutes of Health

Contact: David Orenstein
Brown University

Public Release: 2-Sep-2015
Science Signaling
New genetic mutation identified in melanoma cancer cells
There is strong evidence that the protein complex APC/C may function as a tumor suppressor in multiple cancers including lymphoma, colorectal and breast cancer, and now melanoma. A new study has revealed that a genetic mutation leading to repression of a specific protein, Cdh1, which interacts with APC/C, is present in melanoma cancer cells.
National Institutes for Health, NIH/National Cancer Institute

Contact: Kristen Perfetuo
Boston University Medical Center

Public Release: 2-Sep-2015
Cellular recycling complexes may hold key to chemotherapy resistance
Upsetting the balance between protein synthesis, misfolding, and degradation drives cancer and neurodegeneration. Recent cancer treatments take advantage of this knowledge with a class of drugs that block protein degradation, known as proteasome inhibitors. Widespread resistance to these drugs limits their success, but Whitehead researchers have discovered a potential Achilles heel in resistance. With such understandings researchers may be able to target malignancy broadly, and more effectively.
EMBO, Charles A. King Trust, Koch Institute Frontier Research Program, Kathy and Curt Marble Cancer Research Fund, Alexander and Margaret Stewart Trust, National Institutes of Health, Valvano Foundation

Contact: Nicole Giese Rura
Whitehead Institute for Biomedical Research

Public Release: 2-Sep-2015
Driving with central visual field loss
Vision researchers in Boston have published the second paper of a study designed to determine if a driver who suffers from loss of central vision is able to detect pedestrians in a timely manner when driving. The results of the current study showed that a blind area located above or below the center of interest will still likely block or delay a driver's ability to detect pedestrians entering the field of vision from the side of the road.
National Institutes of Health

Contact: Joseph O'Shea
Massachusetts Eye and Ear Infirmary

Public Release: 2-Sep-2015
Journal of Nutrition
Lowering sugar-sweetened beverage intake by children linked to favorable HDL-C changes
A study measuring blood lipid levels of a diverse sample of Boston area schoolchildren found that reducing SSB intake by at least one serving a week was associated with a greater increase in HDL-cholesterol over 12 months. Higher SSB consumption was also linked to lower fruit and vegetable intake.
NIH/National Heart, Lung, and Blood Institute

Contact: Beverly Freeman
Tufts University, Health Sciences Campus

Public Release: 2-Sep-2015
Nature Communications
Flu study, on hold, yields new vaccine technology
Vaccines to protect against an avian influenza pandemic as well as seasonal flu may be mass produced more quickly and efficiently using technology described today by researchers at the University of Wisconsin-Madison in the journal Nature Communications.
National Institutes of Health, Wisconsin Alumni Research Foundation, Japanese Ministry of Education, Culture, Sports, Science and Technology, Bill and Melinda Gates Foundation

Contact: Yoshihiro Kawaoka
University of Wisconsin-Madison

Public Release: 2-Sep-2015
Science Translational Medicine
Penn researchers report long-term remissions in first personalized cell therapy trial
Eight of 14 patients in the first trial of the University of Pennsylvania's personalized cellular therapy for chronic lymphocytic leukemia (CLL) responded to the therapy, with some complete remissions continuing past four and a half years.
Novartis, Leukemia and Lymphoma Society, National Institutes of Health

Contact: Holly Auer
University of Pennsylvania School of Medicine

Public Release: 1-Sep-2015
ASU team develops quick way to determine bacteria's antibiotic resistance
Bacteria's ability to become resistant to antibiotics is a growing issue in health care: Resistant strains result in prolonged illnesses and higher mortality rates. One way to combat this is to determine bacteria's antibiotic resistance in a given patient, but that often takes days -- and time is crucial in treatment. ASU scientists have developed a technique that can sort antibiotic-resistant from 'susceptible' bacteria, and it happens in a matter of minutes.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jenny Green
Arizona State University

Public Release: 1-Sep-2015
Translational Research
TGen study identifies potential genes associated with the most common form of liver damage
In a first-of-its-kind exploratory study, the Translational Genomics Research Institute has identified a potential gene associated with the initiation of the most common cause of liver damage. Nonalcoholic fatty liver disease is the most common cause of liver damage. In this study, published in the September edition of Translational Research, TGen scientists sequenced microRNAs from liver biopsies, spelling out their biochemical molecules to identify several potential gene targets associated with NAFLD-related liver damage.
TGen, National Institutes of Health

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 1-Sep-2015
Proceedings of the National Academy of Sciences
Penn and German researchers help identify neural basis of multitasking
By studying networks of activity in the brain's frontal cortex, researchers have shown that the degree to which these networks reconfigure themselves while switching from task to task predicts people's cognitive flexibility.
MacArthur Foundation, Sloan Foundation, Army Research Laboratory, NIH/National Institute of Mental Health, National Science Foundation, German Federal Ministry of Education and Research, Innovative Medicines Initiative Joint Undertaking

Contact: Evan Lerner
University of Pennsylvania

Public Release: 1-Sep-2015
Yeast study yields insights into cell-division cycle
Studies using yeast genetics have provided new, fundamental insights into the cell-division cycle, researchers at the University of Michigan Life Sciences Institute report.
National Institutes of Health

Contact: Ian Demsky
University of Michigan

Public Release: 1-Sep-2015
UC San Diego scientists investigate global hemorrhagic fever bacterial disease
An international research team, headed by Joseph Vinetz, M.D., professor of medicine at University of California, San Diego School of Medicine and director of the UC San Diego Center for Tropical Medicine and Travelers Health, has been awarded a five-year, $1.89 million cooperative agreement to carry out transnational research studies of leptospirosis, an infectious and sometimes fatal bacterial disease endemic in much of the world.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Scott LaFee
University of California - San Diego

Public Release: 1-Sep-2015
Alzheimer's & Dementia
Clinical trial is 1st to study impact of cognitive impairment assessment in primary care
The first clinical trial to investigate the impact of primary care physicians testing their patients for cognitive impairment found that doctors given information on a patient's cognitive status provided more care focused on cognition but that care had no impact on the overall rate of the patient's cognitive decline.
NIH/National Institute on Aging

Contact: Cindy Fox Aisen
Indiana University

Public Release: 1-Sep-2015
Molecular Psychiatry
Gene may predict severity of post-traumatic stress disorder
A gene linked in previous research, appears to predict more severe post-traumatic stress disorder (PTSD) symptoms as well as a thinner cortex in regions of the brain critical for regulating strong emotions and coping with stressful experiences. This study is believed to be the first to show that the spindle and kinetochore-associated complex subunit 2 gene may play a role in the development of PTSD.
NIH/National Institute of Mental Health, Translational Research Center for TBI and Stress Disorders, VA Rehabilitation Research and Development Traumatic Brain

Contact: Kristen Perfetuo
Boston University Medical Center

Public Release: 1-Sep-2015
Metabolic Engineering
'Bacterial litmus test' provides inexpensive measurement of micronutrients
A bacterium engineered to produce different pigments in response to varying levels of a micronutrient in blood samples could give health officials an inexpensive way to detect nutritional deficiencies in resource-limited areas of the world. This 'bacterial litmus test,' which currently measures levels of zinc, would require no electrical equipment and make results visible as simple color changes.
Bill & Melinda Gates Foundation, National Science Foundation, National Institutes of Health

Contact: John Toon
Georgia Institute of Technology

Public Release: 1-Sep-2015
Diabetic retinopathy screening for children with type 1 diabetes should start later
Researchers are recommending that most children with type 1 diabetes delay annual diabetic retinopathy screenings until age 15, or five years after their diabetes diagnosis, whichever occurs later.
National Institutes of Health

Contact: Maya Chupkov
American Academy of Ophthalmology

Public Release: 1-Sep-2015
Daily marijuana use among US college students highest since 1980
Daily marijuana use among the nation's college students is on the rise, surpassing daily cigarette smoking for the first time in 2014.
NIH/National Institute on Drug Abuse

Contact: Jared Wadley
University of Michigan

Public Release: 1-Sep-2015
Cancer Research
Modified CAR T cells can preferentially target cancer cells and spare normal cells
Engineering chimeric antigen receptor (CAR) T cells to lower their affinity for the protein epithelial growth factor receptor (EGFR) made the cells preferentially recognize and eliminate tumor cells that have high amounts of EGFR while sparing normal cells that have lower amounts of the protein, according to a preclinical study.
National Institutes of Health

Contact: Julia Gunther
American Association for Cancer Research

Showing releases 1-25 out of 3777.

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