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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 101-125 out of 3538.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 > >>

Public Release: 15-Nov-2014
Society for Neuro-Oncology's 19th Annual Meeting
Chemotherapy following radiation treatment slows disease progress
A chemotherapy regimen consisting of procarbazine, CCNU, and vincristine administered following radiation therapy improved progression-free survival and overall survival in adults with low-grade gliomas, a form of brain cancer, when compared to radiation therapy alone. The findings were part of the results of a Phase III clinical trial presented today at the Society for Neuro-Oncology's 19th Annual Meeting in Miami by the study's primary author Jan Buckner, M.D., deputy director, practice, at Mayo Clinic Cancer Center.
NIH/National Cancer Institute, Radiation Treatment Oncology Group, Alliance for Clinical Trials in Oncology, Eastern Cooperative Oncology Group, Southwest Oncology Group

Contact: Jan Dangor
Mayo Clinic

Public Release: 15-Nov-2014
American College of Rheumatology annual meeting
Blood test could prevent medication trial and error for rheumatoid arthritis patients
A molecule in the blood shows promise as a marker to predict whether individual rheumatoid arthritis patients are likely to benefit from biologic medications or other drugs should be tried, a Mayo Clinic-led study shows. The protein, analyzed in blood tests, may help avoid trial and error with medications, sparing patients treatment delays and unnecessary side effects and expense. The research is among several Mayo Clinic studies presented at the American College of Rheumatology annual meeting in Boston.
Rheumatology Research Foundation, National Institutes of Health

Contact: Sharon Theimer
Mayo Clinic

Public Release: 14-Nov-2014
Cancer Research
New imaging technique identifies receptors for targeted cancer therapy
Dartmouth researchers have developed a fluorescence imaging technique that can more accurately identify receptors for targeted cancer therapies without a tissue biopsy. They report on their findings in 'Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approach,' which was recently published in Cancer Research.
National Institutes of Health

Contact: Robin Dutcher
The Geisel School of Medicine at Dartmouth

Public Release: 14-Nov-2014
Genes & Development
Scientists uncover mechanism that controls the fitness of cells, impacting aging and disease
A novel looping mechanism that involves the end caps of DNA may help explain the aging of cells and how they initiate and transmit disease, according to new research from UT Southwestern Medical Center cell biologists.
NIH/National Institute of Aging, Lung Cancer Specialized Programs of Research Excellence, Austrian Science Fund, American Federation for Aging Research

Contact: Russell Rian
UT Southwestern Medical Center

Public Release: 14-Nov-2014
Pharmaceutical Research
Chemical in coffee may help prevent obesity-related disease
Researchers at the University of Georgia have discovered that a chemical compound commonly found in coffee may help prevent some of the damaging effects of obesity.
National Institutes of Health

Contact: Dexi Liu
University of Georgia

Public Release: 14-Nov-2014
Journal of the International AIDS Society
HIV risks high in Mexico City's male sex trade
The prevalence of sexually transmitted infections, including HIV, and risky behavior are high among Mexico City's male sex workers, a new study reports. Among the findings is that sex workers can make 34.5 percent more money for forgoing condoms. The researchers hope to counteract that incentive with one of their own.
National Institutes of Health, Mexican National Center for HIV/AIDS Control and Prevention, Brown University

Contact: David Orenstein
Brown University

Public Release: 14-Nov-2014
Journal of the American Heart Association
New online calculator estimates cardiovascular disease risk
The new Healthy Heart Score developed by researchers at Harvard School of Public Health gives individuals an easy method to estimate their 20-year risk of developing cardiovascular disease based on simple lifestyle habits.
American Heart Association/Clinical Research Program Award, National Institutes of Health

Contact: Todd Datz
Harvard School of Public Health

Public Release: 14-Nov-2014
Cancer Epidemiology, Biomarkers & Prevention
Nonsmokers in automobiles are exposed to significant secondhand smoke
Nonsmokers sitting in an automobile with a smoker for one hour had markers of significantly increased levels of carcinogens and other toxins in their urine, indicating that secondhand smoke in motor vehicles poses a potentially major health risk according to a groundbreaking study led by University of California San Francisco researchers.
Flight Attendants Medical Research Institute, US Public Health Service, National Institutes of Health

Contact: Elizabeth Fernandez
University of California - San Francisco

Public Release: 13-Nov-2014
Journal of Allergy and Clinical Immunology
Telephone coaches improve children's asthma treatment
A novel program at Washington University School of Medicine in St. Louis suggests that peer trainers who coach parents over the phone on managing their children's asthma can sharply reduce the number of days the kids experience symptoms. The program also dramatically decreased ER visits and hospitalizations among low-income children with Medicaid insurance.
NIH/National Heart, Lung and Blood Institute of the National Institutes of Health

Contact: Diane Duke Williams
Washington University School of Medicine

Public Release: 13-Nov-2014
Acta Neuropathologica
New Alzheimer's-related memory disorder identified
A multi-institutional study has defined and established criteria for a new neurological disease closely resembling Alzheimer's disease called primary age-related tauopathy (PART). Patients with PART develop cognitive impairment that can be indistinguishable from Alzheimer's disease, but they lack amyloid plaques. Awareness of this neurological disease will help doctors diagnose and develop more effective treatments for patients with different types of memory impairment.
Society for Supporting Research in Experimental Neurology, National Institutes of Health

Contact: Laura Dawahare
University of Kentucky

Public Release: 13-Nov-2014
LSU Health New Orleans research targets deadly intra-abdominal infections
Mairi Noverr, Ph.D., associate professor of prosthodontics at LSU Health New Orleans School of Dentistry's Center of Excellence in Oral Biology, has been awarded a $1.8 million grant by the National Institute of Allergy and Infectious Diseases. The funding will support research to reduce the death rate from intra-abdominal infections caused by both fungal and bacterial pathogens. These types of polymicrobial infections are increasingly common among hospitalized patients, have a high death rate, and there has been little research in this area.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Leslie Capo
Louisiana State University Health Sciences Center

Public Release: 13-Nov-2014
Journal of General Physiology
Study offers new clue into how anesthesia works
The activity of ion channel proteins that are important for cell-to-cell communication is markedly reduced during anesthesia, according to researchers from Weill Cornell Medical College.
National Institutes of Health, German Research Foundation

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 13-Nov-2014
Cell Reports
IU researchers identify key mechanism and potential target to prevent leukemia
Researchers have identified two proteins that appear crucial to the development -- and patient relapse -- of acute myeloid leukemia. They have also shown they can block the development of leukemia by targeting those proteins.
National Institutes of Health, Riley Children's Foundation, American Cancer Society

Contact: Eric Schoch
Indiana University

Public Release: 13-Nov-2014
FASEB Journal
U of G scientists find way to reduce ovarian cancer tumors, chemo doses
In a potential breakthrough against ovarian cancer, University of Guelph researchers have discovered how to both shrink tumours and improve drug delivery, allowing for lower doses of chemotherapy and reducing side effects.
Canadian Institutes for Health Research, Ovarian Cancer Canada, National Institutes of Health, Beth Israel Deaconess Medical Center

Contact: Jim Petrik
519-824-4120 x54921
University of Guelph

Public Release: 13-Nov-2014
Cell Reports
Total recall: The science behind it
Is it possible to change the amount of information the brain can store? Maybe, according to a new international study led by the RI-MUHC. Their research has identified a molecule that puts a brake on brain processing and when removed, brain function and memory recall is improved. Published in the latest issue of Cell Reports, the study has implications for neurodevelopmental and neurodegenerative diseases, such as autism spectral disorders and Alzheimer's disease.
Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council of Canada, National Institutes of Health

Contact: Julie Robert
514-934-1934 x71381
McGill University Health Centre

Public Release: 13-Nov-2014
Journal of Biological Chemistry
Common cholesterol-fighting drug may prevent hysterectomies in women with uterine fibroids
Researchers at the University of Texas Medical Branch at Galveston, in collaboration with The University of Texas Health Science Center at Houston, Baylor College of Medicine and the Georgia Regents University, report for the first time that the cholesterol-lowering drug simvastatin inhibits the growth of human uterine fibroid tumors. These new data are published online and scheduled to appear in the January print edition of the Journal of Biological Chemistry.
National Institutes of Health, UTMB Institute for Translational Sciences, University of Texas Health Sciences Center at Houston

Contact: Donna Ramirez
University of Texas Medical Branch at Galveston

Public Release: 13-Nov-2014
Nature Communications
UCI team develops test to rapidly diagnose bloodstream infection
A new bloodstream infection test created by UC Irvine researchers can speed up diagnosis times with unprecedented accuracy, allowing physicians to treat patients with potentially deadly ailments more promptly and effectively.
UCI's Department of Pharmaceutical Sciences, Sue & Bill Gross Stem Cell Research Center, Chao Family Comprehensive Cancer Center, National Institutes of Health

Contact: Tom Vasich
University of California - Irvine

Public Release: 13-Nov-2014
Molecular Cancer Therapeutics
UNC researchers silence leading cancer-causing gene
Researchers have developed a new approach to block the KRAS oncogene, one of the most frequently mutated genes in human cancer. The approach offers another route to attack KRAS, which has proven to be an elusive and frustrating target for drug developers.
National Institutes of Health

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 13-Nov-2014
Study finds Alzheimer's drug may reduce the urge to binge eat
The Alzheimer's drug memantine may perform double-duty helping binge eaters control their compulsion. Researchers have demonstrated that memantine, a neuroprotective drug, may reduce the addictive and impulsive behavior associated with binge eating.
NIH/National Institute on Drug Abuse, NIH/National Institute of Mental Health Peter Paul Career Development Professorship, McManus Charitable Trust

Contact: Gina DiGravio
Boston University Medical Center

Public Release: 13-Nov-2014
Clinical Cancer Research
Cancer-killing virus plus chemotherapy drug might treat recurrent ovarian cancer
In six out of 10 cases, ovarian cancer is diagnosed when the disease is advanced and five-year survival is only 27 percent. A new study suggests that a cancer-killing virus combined with a chemotherapy drug might safely and effectively treat advanced or recurrent forms of the disease.
NIH/National Cancer Institute

Contact: Darrell E. Ward
Ohio State University Wexner Medical Center

Public Release: 13-Nov-2014
ACS Nano
Rutgers Chemistry's Ki-Bum Lee patents technology to advance stem cell therapeutics
Rutgers researchers have developed a highly robust, efficient nanoparticle-based platform that can regulate gene expression and eventually stem cell differentiation. NanoScript is the first nanomaterial TF protein that can interact with endogenous DNA.
National Institutes of Health

Contact: Fred Feiner
Rutgers University

Public Release: 13-Nov-2014
Current Biology
For female chimpanzees, no consent agreement
In the animal kingdom, the battle of the sexes often truly becomes a battle. Among chimpanzees, males may violently attack females, sometimes resulting in serious wounds. While unpleasant to watch, the frequent occurrence of such violence at several East African field sites suggests that aggression toward females functions as a form of sexual coercion.
Jane Goodall Institute, National Science Foundation, National Institutes of Health, University of Minnesota, Harris Steel Group, Windibrow Foundation, Carnegie Corporation

Contact: Ian Gilby
Arizona State University

Public Release: 13-Nov-2014
Bacteria become 'genomic tape recorders'
MIT researchers find engineered E. coli can store long-term memories of chemical exposure, other events in their DNA.
National Institutes of Health, Office of Naval Research, Defense Advanced Research Projects Agency

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 13-Nov-2014
Current Biology
Male bullies father more chimpanzees
In a long-term study of interactions between chimpanzees in the famous Gombe National Park in Tanzania, researchers have found that males who consistently bully females tend to father more babies with their victims.
Jane Goodall Institute, National Science Foundation, National Institutes of Health, Carnegie Corporation, University of Minnesota, Duke University, Harris Steel Group, Windibrow Foundation

Contact: Karl Leif Bates
Duke University

Public Release: 13-Nov-2014
Direct drug screening of patient biopsies could overcome resistance to targeted therapy
A new screening platform using cells grown directly from tumor biopsy samples may lead to truly individualized treatment strategies that would get around the problem of treatment resistance, which limits the effectiveness of current targeted therapy drugs.
National Institutes of Health, Wellcome Trust, Department of Defense, Conquer CNational Institutes of Health, Wellcome Trust, US Department of Defense, Coancer Foundation, Uniting Against Lung Cancer, Free to Breathe, Lungevity, Be a Piece of the Solution

Contact: Katie Marquedant
Massachusetts General Hospital

Showing releases 101-125 out of 3538.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 > >>


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