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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 101-125 out of 3396.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 > >>

Public Release: 10-Apr-2014
Chemistry & Biology
Enzyme 'wrench' could be key to stronger, more effective antibiotics
Builders and factory workers know that getting a job done right requires precision and specialized tools. The same is true when you're building antibiotic compounds at the molecular level. New findings from North Carolina State University may turn an enzyme that acts as a specialized 'wrench' in antibiotic assembly into a set of wrenches that will allow for greater customization.
National Science Foundation, National Institutes of Health

Contact: Tracey Peake
tracey_peake@ncsu.edu
919-515-6142
North Carolina State University

Public Release: 10-Apr-2014
Science
How the brain pays attention
MIT neuroscientists identify a brain circuit that's key to shifting our focus from one object to another.
National Institutes of Health, National Science Foundation

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Public Release: 10-Apr-2014
eLife
Planaria deploy an ancient gene expression program in the course of organ regeneration
In the April 15, 2014, issue of the online journal eLife, Stowers Institute for Medical Research Investigator Alejandro Sanchez Alvarado and colleagues report the identification of genes that worms use to rebuild an amputated pharynx.
Stowers Institute for Medical Research, National Institutes of Health, Howard Hughes Medical Institute

Contact: Kim Bland, Ph.D.
ksb@stowers.org
816-926-4015
Stowers Institute for Medical Research

Public Release: 10-Apr-2014
American Journal of Public Health
HIV battle must focus on hard-hit streets, paper argues
When it comes to HIV, geography can be destiny, argue authors of a new article in the American Journal of Public Health. The epidemic has become heavily concentrated in poor urban neighborhoods where people are less likely to be tested and treated, creating more risk that the virus will spread. New prevention efforts should focus on neighborhoods.
National Institutes of Health, California HIV Research Program, and Gilead Sciences HIV focus program

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 10-Apr-2014
Cell Reports
Penn study finds mechanism that regulates lung function in disease Birt-Hogg-Dube syndrome
Researchers at Penn Medicine have discovered that the tumor suppressor gene folliculin is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube syndrome, a genetic disorder that affects the lungs, skin and kidneys. Folliculin's absence or mutated state has a cascading effect that leads to deteriorated lung integrity and an impairment of lung function, as reported in their findings in Cell Reports.
National Institutes of Health

Contact: Lee-Ann Donegan
leeann.donegan@uphs.upenn.edu
215-349-5660
University of Pennsylvania School of Medicine

Public Release: 10-Apr-2014
Neuron
Yale researchers search for earliest roots of psychiatric disorders
Now, Yale University researchers have identified a single molecular mechanism in the developing brain that sheds light on how cells may go awry when exposed to a variety of different environmental insults. The findings, to be published in the May 7 issue of the journal Neuron, suggest that different types of stressors prenatally activate a single molecular trigger in brain cells that may make exposed individuals susceptible to late-onset neuropsychiatric disorders.
National Institutes of Health

Contact: Bill Hathaway
william.hathaway@yale.edu
203-432-1322
Yale University

Public Release: 10-Apr-2014
Cell
Researchers determine how mechanical forces affect T-cell recognition and signaling
Researchers have developed a new understanding of the T-cell recognition process by describing how T-cell receptors use mechanical contact -- the forces involved in their binding to the antigens -- to make decisions about whether or not the cells they encounter are threats.
National Institutes of Health

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology

Public Release: 10-Apr-2014
Cell Metabolism
Lactate metabolism target halts growth in lung cancer model
A team led by investigators at Beth Israel Deaconess Medical Center has found that an enzyme responsible for the final step of glucose metabolism not only halts tumor growth in non-small-cell lung cancer, but actually leads to regression of established tumors.
National Institutes of Health, US Department of Defense

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 10-Apr-2014
Cell
Getting to the root of Parkinson's disease
Working with human neurons and fruit flies, researchers at Johns Hopkins have identified and then shut down a biological process that appears to trigger a particular form of Parkinson's disease present in a large number of patients. A report on the study, in the April 10 issue of the journal Cell, could lead to new treatments for this disorder.
NIH/National Institute of Neurological Disorders and Stroke, JPB Foundation, Maryland Stem Cell Research Fund, Adrienne Helis Malvin Medical Research Foundation, Diana Helis Henry Medical Research Foundation

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Public Release: 10-Apr-2014
Science
Wiring for smell sets up early, then persists
A new study in Science reveals that the fundamental wiring of the olfactory system in mice sets up shortly after birth and then remains stable but adaptable. The research highlights how important early development can be throughout life and provides insights that may be important in devising regenerative medical therapies in the nervous system.
National Institutes of Health, Pew Scholar in Biomedical Sciences

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 10-Apr-2014
Cell
Team solves decades-old mystery of how cells keep from bursting
A team led by scientists at the Scripps Research Institute has identified a long-sought protein that facilitates one of the most basic functions of cells: regulating their volume to keep from swelling excessively.
National Institutes of Health

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 9-Apr-2014
Proceedings of the National Academy of Sciences
CU researchers unraveling what's behind the sniffles, hoping for a treatment
Scientists at the University of Colorado School of Medicine have shed light on one of the most common of ailments -- the runny nose. Understanding the cause could lead to a cure.
National Institutes of Health

Contact: Dan Meyers
dan.meyers@ucdenver.edu
University of Colorado Denver

Public Release: 9-Apr-2014
NCI award supports access to national clinical trials to test new treatment for adults
UT Southwestern has been selected as one of only 30 academic sites in the NCI National Clinical Trials Network, giving UTSW patients access to the cancer research trials sponsored by the NCI.
NIH/National Cancer Institute

Contact: Patrick McGee
patrick.mcgee@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 9-Apr-2014
Clinical & Experimental Metastasis
TGen identifies growth factor receptors that may prompt metastatic spread of lung cancer
Two cell surface receptors might be responsible for the most common form of lung cancer spreading to other parts of the body, according to a study by the Translational Genomics Research Institute. The hepatocyte growth factor receptor and fibroblast growth factor-inducible 14 are proteins associated with the potential spread of non-small cell lung cancer, according to the TGen study published online April 8 by the scientific journal Clinical & Experimental Metastasis.
National Institutes of Health, St. Joseph's Foundation, American Lung Association

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 9-Apr-2014
UCLA/RAND community research team win prestigious translational science award
A team of community leaders and researchers from UCLA and RAND has been awarded the 2014 Joint Team Science Award in recognition of a 10-year effort to conduct community engaged, population-based translational science to improve care for depression in low-income areas.
NIH/National Institute of Mental Health, UCLA Clinical and Translational Science Institute

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-2262
University of California - Los Angeles Health Sciences

Public Release: 9-Apr-2014
American Journal of Kidney Diseases
Vigilance for kidney problems key for rheumatoid arthritis patients
Rheumatoid arthritis patients are likelier than the average person to develop chronic kidney disease, and more severe inflammation in the first year of rheumatoid arthritis, corticosteroid use, high blood pressure and obesity are among the risk factors, new Mayo Clinic research shows.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH/National Institute on Aging

Contact: Sharon Theimer
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

Public Release: 9-Apr-2014
Journal of Nutritional Biochemistry
UC-led research finds chips with olestra cause body toxins to dip
According to a clinical trial led by University of Cincinnati researchers, a snack food ingredient called olestra has been found to speed up the removal of toxins in the body.
National Institutes of Health

Contact: Angela Koenig
angela.koenig@uc.edu
513-558-4625
University of Cincinnati Academic Health Center

Public Release: 9-Apr-2014
Biomacromolecules
Synthetic collagen promotes natural clotting
Synthetic collagen invented at Rice University may help wounds heal by directing the natural clotting of blood.
National Institutes of Health, National Science Foundation, Robert A. Welch Foundation

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Public Release: 9-Apr-2014
Grant awarded to study impact of pain medication exposure in the womb on developing brain
Scientists from the Florida campus of the Scripps Research Institute have been awarded a $472,500 Cutting Edge Basic Research Award by the National Institute on Drug Abuse of the National Institutes of Health to study models of the brain development of newborns who have been exposed -- and become addicted -- to prescription pain medication while still in the womb.
National Institutes of Health

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 9-Apr-2014
Neurology
Bone marrow stem cells show promise in stroke treatment, UCI team finds
Stem cells culled from bone marrow may prove beneficial in stroke recovery, scientists at UC Irvine's Sue & Bill Gross Stem Cell Research Center have learned.
National Center for Research Resources, National Institutes of Health

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine

Public Release: 9-Apr-2014
Journal of Biological Chemistry
Green is good
Using a screening method that previously identified a compound in apple peel as a muscle-boosting agent, a team of University of Iowa scientists has now discovered that tomatidine, a compound from green tomatoes, is even more potent for building muscle and protecting against muscle atrophy.
National Institutes of Health, Department of Veterans Affairs, University of Iowa Fraternal Order of Eagles Diabetes Research Center

Contact: Jennifer Brown
jennifer-l-brown@uiowa.edu
319-356-7124
University of Iowa Health Care

Public Release: 9-Apr-2014
NIH grant to further SLU research on link between prescription painkillers and depression
An epidemiologist explores which patients are more susceptible to depression.
National Institutes of Health

Contact: Riya Anandwala
ranandwa@slu.edu
314-977-8018
Saint Louis University

Public Release: 9-Apr-2014
Proceedings of the National Academy of Sciences
Stressful environments genetically affect African-American boys
Stressful upbringings can leave imprints on the genes of children, including African-American boys, according to a study led by Princeton University and the Pennsylvania State University. Such chronic stress during youth leads to physiological weathering similar to aging.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, Penn State Clinical

Contact: B. Rose Huber
brhuber@princeton.edu
609-258-0157
Princeton University, Woodrow Wilson School of Public and International Affairs

Public Release: 9-Apr-2014
Nature Cell Biology
UNC researchers show how cancer cells may respond to mechanical force
Two UNC-Chapel Hill studies, published in Nature Cell Biology and the Journal of Immunology, identify the processes and cellular pathways that allow cells to move, stiffen, and react to physical stresses. This knowledge, researchers hope, could reveal the causes of cancer and help develop treatments, including therapies for a variety of diseases.
National Institutes of Health

Contact: William Davis
william_davis@med.unc.edu
919-966-5906
University of North Carolina Health Care

Public Release: 9-Apr-2014
Nature
UC San Diego researchers develop bacterial 'FM radio'
A team of biologists and engineers at UC San Diego has developed a 'rapid and tunable post-translational coupling' for genetic circuits.
National Institutes of Health, National Science Foundation

Contact: Kim McDonald
kmcdonald@ucsd.edu
858-534-7572
University of California - San Diego

Showing releases 101-125 out of 3396.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 > >>

     
   

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