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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 101-125 out of 3479.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 > >>

Public Release: 23-Sep-2014
Lab on a Chip
Airway muscle-on-a-chip mimics asthma
New drugs are urgently needed to treat asthma. Hope may be on the horizon thanks to a team that has developed a human airway muscle-on-a-chip that accurately mimics the way smooth muscle contracts in the human airway, under normal circumstances and when exposed to asthma triggers. As reported in the journal Lab on a Chip, it also offers a window into the cellular and even subcellular responses within the tissue during an asthmatic event.
National Institutes of Health, Harvard SEAS

Contact: Kristen Kusek
Wyss Institute for Biologically Inspired Engineering at Harvard

Public Release: 23-Sep-2014
Cancer Research
Study uncovers genetic driver of inflammation, uses it to prevent and treat liver cancer
Scientists at Virginia Commonwealth University Massey Cancer Center have demonstrated for the first time in preclinical studies that blocking the expression of a gene known as astrocyte elevated gene-1 halts the development and progression of liver cancer by regulating inflammation.
NIH/National Cancer Institute, James S. McDonnell Foundation

Contact: John Wallace
Virginia Commonwealth University

Public Release: 23-Sep-2014
Journal of Neuroscience
Dying brain cells cue new brain cells to grow in songbird
Using a songbird as a model, scientists have described a brain pathway that replaces cells that have been lost naturally and not because of injury. If scientists can further tap into the process and understand how those signals work, it might lead to ways to encourage replacement of cells in human brains that have lost neurons naturally because of aging or Alzheimer's disease.
National Institutes of Health, University of Washington

Contact: Sandra Hines
University of Washington

Public Release: 23-Sep-2014
Study questions accuracy of lung cancer screens in some geographic regions
A new analysis of published studies found that FDG-PET technology is less accurate in diagnosing lung cancer versus benign disease in regions where infections like histoplasmosis or tuberculosis are common. Misdiagnosis of lung lesions suspicious for cancer could lead to unnecessary tests and surgeries for patients, with additional potential complications and mortality.
Agency for Healthcare Research and Quality, National Institutes of Health, Department of Veterans Affairs

Contact: Craig Boerner
Vanderbilt University Medical Center

Public Release: 23-Sep-2014
Nature Communications
A multi-function protein is key to stopping genomic parasites from 'jumping'
Most organisms, including humans, have parasitic DNA fragments called 'jumping genes' that insert themselves into DNA molecules, disrupting genetic instructions in the process. And that phenomenon can result in age-related diseases such as cancer. But researchers at the University of Rochester now report that the 'jumping genes' in mice become active as the mice age when a multi-function protein stops keeping them in check in order to take on another role.
National Institutes of Health

Contact: Peter Iglinski
University of Rochester

Public Release: 23-Sep-2014
Critically ill ICU patients lose almost all of their gut microbes and the ones left aren't good
Researchers at the University of Chicago have shown that after a long stay in the Intensive Care Unit only a handful of pathogenic microbe species remain behind in patients' intestines. The team tested these remaining pathogens and discovered that some can become deadly when provoked by conditions that mimic the body's stress response to illness.
National Institutes of Health, US Department of Energy

Contact: Jim Sliwa
American Society for Microbiology

Public Release: 23-Sep-2014
Alcoholism: Clinical & Experimental Research
Alcohol-evoked drinking sensations differ among people as a function of genetic variation
Taste strongly influences food and beverage intake, including alcohol. A new study looks at the relationship between alcohol-related sensations and polymorphisms in bitter and burn receptor genes. Findings indicate that genetic variations in taste receptors influence intensity perceptions.
National Institutes of Health

Contact: John E. Hayes
Alcoholism: Clinical & Experimental Research

Public Release: 23-Sep-2014
Alcoholism: Clinical & Experimental Research
First drink to first drunk
An early age of onset of drinking is a risk factor for subsequent heavy drinking and negative outcomes. New research looks at both an early AO, as well as a quick progression from initial alcohol use to drinking to the point of intoxication, as risk factors. Findings indicate that both are associated with high-school student alcohol use and binge drinking.
National Institutes of Health

Contact: Meghan E. Morean
Alcoholism: Clinical & Experimental Research

Public Release: 23-Sep-2014
Alcoholism: Clinical & Experimental Research
Higher cigarette taxes and stronger smoke-free policies may reduce alcohol consumption
Increasing cigarette taxes and smoke-free policies are known to reduce smoking prevalence. New findings show that these measures may also lead to a decrease in alcohol consumption. These findings apply to beer and spirits, but not wine.
National Institutes of Health

Contact: Melissa J. Krauss, M.P.H.
Alcoholism: Clinical & Experimental Research

Public Release: 23-Sep-2014
Alcoholism: Clinical & Experimental Research
Best friends' drinking can negate the protective effects of an alcohol dehydrogenase 1B gene variant
Alcohol use that begins during adolescence affects the development of alcohol use disorders during adulthood. A new study looks at the effects of interplay between peer drinking and the functional variant rs1229984 in the alcohol dehydrogenase 1B gene (ADH1B) among adolescents. Peer drinking reduces the protective effects of this ADH1B variant.
National Institutes of Health

Contact: Laura J. Bierut
Alcoholism: Clinical & Experimental Research

Public Release: 22-Sep-2014
Health Psychology
We drink more alcohol on gym days
A new Northwestern Medicine study finds that on days when people exercise more -- typically Thursdays to Sundays -- they drink more alcohol, too.
NIH/National Institute on Aging, NIH/National Institute on Drug Abuse

Contact: Erin White
Northwestern University

Public Release: 22-Sep-2014
Cell Reports
Massachusetts General study reveals gene expression patterns in pancreatic CTCs
Analysis of circulating tumor cells in a mouse model of pancreatic cancer identified distinct patterns of gene expression in several groups of CTCs, including significant differences from the primary tumor that may contribute to the ability to generate metastases. The Massachusetts General Hospital Cancer Center investigators identified several different classes of pancreatic CTCs and found unexpected factors that may prove to be targets for improved treatment of the deadly tumor.
Stand Up to Cancer, Howard Hughes Medical Institute, Burroughs Wellcome Fund, NIH/National Institute of Biomedical Imaging and Bioengineering, NIH/National Cancer Institute, Affymetrix, Inc.

Contact: Katie Marquedant
Massachusetts General Hospital

Public Release: 22-Sep-2014
Journal of Controlled Release
New chip promising for tumor-targeting research
Researchers have developed a chip capable of simulating a tumor's 'microenvironment' and plan to use the new system to test the effectiveness of nanoparticles and drugs that target cancer.
National Science Foundation, National Institutes of Health

Contact: Emil Venere
Purdue University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Genetic switch regulates a plant's internal clock based on temperature
Scientists have found the molecular cog in a plant's biological clock that modulates its speed based on temperature.
The Ruth L. Kirschstein National Research Service Award, National Instiutes of Health, NIH/National Institute of General Medical Sciences

Contact: Robert Perkins
University of Southern California

Public Release: 22-Sep-2014
Rutgers receives $2 million grant to prepare biomedical students for roles in industry
Rutgers' School of Engineering and Rutgers Graduate School of Biomedical Sciences are joint recipients of a $2 million 2014 BEST grant from the National Institutes of Health. Once upon a time, students seeking advanced degrees in the biomedical sciences generally expected to find careers in academia, and their mentors expected them to do so. No longer. Fewer than half of those students now end up in academia. So the National Institutes of Health created the BEST grant, aimed at preparing students for potential careers in industry and other non-academic areas.
National Institutes of Health

Contact: Rob Forman
Rutgers University

Public Release: 22-Sep-2014
Behavioral Brain Research
Compound from hops aids cognitive function in young animals
Xanthohumol, a type of flavonoid found in hops and beer, has been shown in a new study to improve cognitive function in young mice, but not in older animals. The findings are another step toward understanding, and ultimately reducing the degradation of memory that happens with age in many mammalian species, including humans.
National Institutes of Health

Contact: Kathy Magnusson
Oregon State University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Variability keeps the body in balance
Although the heart beats out a very familiar 'lub-dub' pattern that speeds up or slows down as our activity increases or decreases, the pattern itself isn't as regular as you might think. In fact, the amount of time between heartbeats can vary even at a 'constant' heart rate -- and that variability, doctors have found, is a good thing.
John G. Braun Professorship, Air Force Office of Scientific Research, National Science Foundation, Pfizer, National Institutes of Health, Institute of Collaborative Biotechnologies

Contact: Deborah Williams-Hedges
California Institute of Technology

Public Release: 22-Sep-2014
Brain, Behavior and Immunity
Obesity and stress pack a double hit for health
If you're overweight, you may be at greater risk for stress-related diseases like type 2 diabetes, cardiovascular disease and cancer, according to a new study by Brandeis University. In a recently published paper in Brain, Behavior and Immunity, Brandeis researchers observed that overweight and obese individuals have higher levels of stress-induced inflammation than those within a healthy weight-range.
American Federation of Aging Research, National Institutes of Health

Contact: Leah Burrows
Brandeis University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Platelets modulate clotting behavior by 'feeling' their surroundings
Platelets respond to surfaces with greater stiffness by increasing their stickiness, the degree to which they "turn on" other platelets and other components of the clotting system, Emory and Georgia Tech researchers found.
National Science Foundation, American Heart Association, NIH/National Heart Lung Blood Institute, NIH/National Eye Institute

Contact: Quinn Eastman
Emory Health Sciences

Public Release: 22-Sep-2014
Mammalian Genome
Lack of thyroid hormone blocks hearing development
Fatigue, weight gain, chills, hair loss, anxiety, excessive perspiration -- these symptoms are a few of the signs that the thyroid gland has gone haywire. Harnessing electron microscopy to track the inner hair cells of the cochlea in two groups of mice, new research from Tel Aviv University points to an additional complication caused by an imbalance in the thyroid gland: congenital deafness.
National Institutes of Health, I-CORE Gene Regulation in Complex Human Disease

Contact: George Hunka
American Friends of Tel Aviv University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Lego-like modular components make building 3-D 'labs-on-a-chip' a snap
Thanks to new Lego-like components developed by researchers at the University of Southern California Viterbi School of Engineering, it is now possible to build a 3-D microfluidic system (or 'lab-on-a-chip') quickly and cheaply by simply snapping together small modules by hand.
National Institutes of Health

Contact: Megan Hazle
University of Southern California

Public Release: 22-Sep-2014
JAMA Pediatrics
Cytomegalovirus linked to maternal breast milk in very-low-birth-weight infants
The primary source of postnatal infection with cytomagelovirus, a common virus usually without symptoms in very-low-birth-weight infants appeared to be maternal breast milk because no infections were linked to transfusions of cytomagelovirus-seronegative and leukoreduced blood products.
NIH/National Heart, Lung and Blood Institute

Contact: Holly Korschun
The JAMA Network Journals

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
The fine line between breast cancer and normal tissues
Researchers at Brigham and Women's Hospital have successfully tested a tool they developed that will help surgeons better distinguish cancerous breast tissue from normal tissue, thereby decreasing the chances for repeat operations.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
Brigham and Women's Hospital

Public Release: 22-Sep-2014
Journal of Experimental Medicine
New rules for anticancer vaccines
Scientists have found a way to find the proverbial needle in the cancer antigen haystack. The results have the potential to completely change current approaches to generating anticancer vaccines.
Cancer Research Institute NY, Northeastern Utilities, Connecticut Institute for Clinical and Translational Science, SPARK, National Science Foundation, National Institutes of Health, Life Technologies, USDA/National Institute of Food and Agriculture

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 22-Sep-2014
Journal of Autism and Developmental Disorders
Brainwave test could improve autism diagnosis and classification
A new study by researchers at Albert Einstein College of Medicine of Yeshiva University suggests that measuring how fast the brain responds to sights and sounds could help in objectively classifying people on the autism spectrum and may help diagnose the condition earlier. The paper was published today in the online edition of the Journal of Autism and Developmental Disabilities.
NIH/National Institute of Mental Health

Contact: Kim Newman
Albert Einstein College of Medicine

Showing releases 101-125 out of 3479.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 > >>


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