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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 126-150 out of 3760.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>

Public Release: 23-Jun-2015
Ophthalmology
Bionic eye clinical trial results show long-term safety, efficacy vision-restoring implant
The three-year clinical trial results of the retinal implant popularly known as the 'bionic eye,' have proven the long-term efficacy, safety and reliability of the device that restores vision in those blinded by a rare, degenerative eye disease. The findings show that the Argus II significantly improves visual function and quality of life for people blinded by retinitis pigmentosa. They are being published online today in Ophthalmology, the journal of the American Academy of Ophthalmology.
National Institutes of Health, NIH/National Eye Institute, Second Sight Medical Products Inc.

Contact: Dayle Kern
dkern@aao.org
415-447-0375
American Academy of Ophthalmology

Public Release: 23-Jun-2015
Cell Transplantation
Stem cell injections improve diabetic neuropathy in animal models
Rats modeled with diabetic neuropathy were randomly assigned to BM-MSC or saline injection 12 weeks after diabetes modeling to investigate whether local transplantation could attenuate or reverse experimental DN. The study provided the first evidence that intramuscular injected BM-MSCs migrated to nerves and increased angiogenic and neurotrophic factors associated with blood vessel growth, aiding the survival of nerves. Results suggested that BM-MSC transplantation restored both the myelin sheath and nerve cells in sciatic nerves.
National Institutes of Health, National Science Foundation-Emergent Behavior of Integrated Cellular Systems

Contact: Robert Miranda
cogcomm@aol.com
Cell Transplantation Center of Excellence for Aging and Brain Repair

Public Release: 23-Jun-2015
Nature Genetics
Study identifies multiple genetic changes linked to increased pancreatic cancer risk
In a genome-wide association study believed to be the largest of its kind, Johns Hopkins researchers have uncovered four regions in the human genome where changes may increase the risk of pancreatic cancer.
National Institutes of Health

Contact: Ekaterina Pesheva
epeshev1@jhmi.edu
410-502-9433
Johns Hopkins Medicine

Public Release: 23-Jun-2015
Journal of Neuroscience
Quiet that ringing in the brain
Epilepsy and tinnitus are both caused by overly excitable nerve cells. Healthy nerves have a built-in system that slams on the brakes when they get too excited. The 'brakes' are actually potassium channels that regulate nerve signals. A new drug may treat both conditions by selectively opening potassium channels in the brain.
US National Institutes of Health, Department of Defense

Contact: Kim Krieger
Kim.Krieger@uconn.edu
860-486-0361
University of Connecticut

Public Release: 23-Jun-2015
Molecular Psychiatry
UCI-led study demonstrates how Huntington's disease proteins spread from cell to cell
By identifying in spinal fluid how the characteristic mutant proteins of Huntington's disease spread from cell to cell, UC Irvine scientists and colleagues have created a new method to quickly and accurately track the presence and proliferation of these neuron-damaging compounds -- a discovery that may accelerate the development of new drugs to treat this incurable disease.
National Institutes of Health

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine

Public Release: 23-Jun-2015
With NIH award, professor aims to ease a 'bottleneck' in vaccine development
North­eastern pro­fessor of chem­ical engi­neering Shashi Murthy has received a four-year, $1.4 mil­lion award from the National Insti­tutes of Health to develop a novel instru­ment that would auto­mate an impor­tant process used in cre­ating effec­tive vaccines.
National Institutes of Health

Contact: Jessica Caragher
j.caragher@neu.edu
617-373-3287
Northeastern University

Public Release: 23-Jun-2015
Journal of Immunology
When inflammation occurs, kidneys work to protect themselves, researchers find
In an apparent effort to help themselves, inflamed kidney cells produce one of the same inflammation-suppressing enzymes fetuses use to survive, researchers report.
National Institutes of Health

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Public Release: 23-Jun-2015
Science Signaling
Potential treatment target identified for rare form of diabetes, other disorders
Scientists working to find treatments for a rare and severe form of diabetes known as Wolfram syndrome have identified a gatekeeper that prevents harmful molecules from spilling and triggering cell death. The researchers, at Washington University School of Medicine in St. Louis, also have found that the gatekeeper -- an enzyme -- may be a good treatment target not only for diabetes but for heart problems, Parkinson's disease and other disorders.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Heart, Lung, and Blood Institute, US Department of Veterans Affairs, Juvenile Diabetes Research Foundation, American Diabetes Association, and others

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine

Public Release: 23-Jun-2015
JAMA
Dietary guidelines for Americans shouldn't place limits on total fat intake
In a Viewpoint published today in the Journal of the Medical Association (JAMA), researchers from the Friedman School of Nutrition Science and Policy at Tufts University and Boston Children's Hospital call on the federal government to drop restrictions on total fat consumption in the forthcoming 2015 Dietary Guidelines for Americans.
NIH/National, Heart, Lung and Blood Institute, NIH/National Institute of Diabetes and Digestive Kidney Diseases

Contact: Andrea Grossman
617-636-3728
Tufts University, Health Sciences Campus

Public Release: 23-Jun-2015
Clinical Psychological Science
Brain scans of passengers who experienced nightmare flight
Toronto -- A group of passengers who thought they were going to die when their plane ran out of fuel over the Atlantic Ocean in August, 2001 have had their brains scanned while recalling the terrifying moments to help science better understand trauma memories and how they are processed in the brain.
Canadian Institutes of Health Research, NIH/National Institute of Mental Health

Contact: Kelly Connelly
kconnelly@baycrest.org
416-785-2432
Baycrest Centre for Geriatric Care

Public Release: 23-Jun-2015
Molecular Psychiatry
Medication may stop drug and alcohol addiction
Researchers have successfully stopped cocaine and alcohol addiction in experiments using a drug already approved by the US Food and Drug Administration to treat high blood pressure.
NIH/National Institute on Drug Abuse, NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Marc Airhart
mairhart@austin.utexas.edu
512-232-1066
University of Texas at Austin

Public Release: 23-Jun-2015
Journal of Adolescent Health
Adolescents uncertain about risks of marijuana, e-cigarettes, Stanford study finds
Teenagers are very familiar with the risks of smoking cigarettes, but are much less sure whether marijuana or e-cigarettes are harmful, according to a new study by researchers at the Stanford University School of Medicine.
NIH/National Cancer Institute

Contact: Erin Digitale
digitale@stanford.edu
650-724-9175
Stanford University Medical Center

Public Release: 23-Jun-2015
Radiology
CT allows nonsurgical management of some lung nodules
People who have nonsolid lung nodules can be safely monitored with annual low-dose computed tomography screening, according to a new study. Researchers said the findings could help spare patients from unnecessary surgery and additional imaging.
National Institutes of Health

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

Public Release: 22-Jun-2015
JAMA Internal Medicine
Obesity, excess weight in US continue upswing
Obesity and excess weight, and their negative impact on health, have become a significant focus for physicians and other health-care experts in recent years. But new research at Washington University School of Medicine in St. Louis shows that an escalation in the number of those considered obese or overweight in the United States continues, signaling an ongoing upward swing in chronic health conditions as well.
National Cancer Institute, National Institutes of Health, Siteman Cancer Center

Contact: Judy Martin
martinju@wustl.edu
314-286-0105
Washington University School of Medicine

Public Release: 22-Jun-2015
Proceedings of the National Academy of Sciences
How understanding GPS can help you hit a curveball
Our brains track moving objects by applying one of the algorithms your phone's GPS uses, according to researchers at the University of Rochester. This same algorithm also explains why we are fooled by several motion-related optical illusions, including the sudden 'break' of baseball's well known 'curveball illusion.'
National Institutes of Health

Contact: Monique Patenaude
monique.patenaude@rochester.edu
585-276-3693
University of Rochester

Public Release: 22-Jun-2015
Clinical Journal of the American Society of Nephrology
Study shows importance of cause of kidney failure when planning future treatment
Stanford researchers used big data to determine that mortality rates for patients whose kidney failure was attributed to glomerulonephritis vary significantly according to which subtype of the disease they had. These results suggest that treatment plans should vary according to root causes of kidney failure.
ASN Foundation for Kidney Research, National Institutes of Health

Contact: Ruthann Richter
richter1@stanford.edu
650-725-8047
Stanford University Medical Center

Public Release: 22-Jun-2015
JAMA Internal Medicine
Weight-loss surgery may greatly improve incontinence
For severely obese people, bariatric surgery may have a benefit besides dramatic weight loss: it can also substantially reduce urinary incontinence.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Elizabeth Fernandez
elizabeth.fernandez@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 22-Jun-2015
Annals of Internal Medicine
Study finds most women with lupus can have good pregnancy outcomes
One of the most prevalent and anxiety-provoking concerns among patients with lupus is whether it is safe to become pregnant. A pioneering study led by researchers at Hospital for Special Surgery (HSS) has shown that most women can expect a good pregnancy outcome if their lupus is inactive and they are free of certain risk factors.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Robin Frank
FrankR@hss.edu
516-773-0319
Hospital for Special Surgery

Public Release: 22-Jun-2015
Endocrinology
Penn: Mom's stress alters babies' gut and brain through vaginal microbiome
Stress during the first trimester of pregnancy alters the population of microbes living in a mother's vagina. Those changes are passed on to newborns during birth and are associated with differences in their gut microbiome as well as their brain development, according to a new study by University of Pennsylvania researchers.
NIH/National Institute of Mental Health

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 22-Jun-2015
Journal of the American College of Cardiology
'High-normal' blood pressure in young adults spells risk of heart failure in later life
Mild elevations in blood pressure considered to be in the upper range of normal during young adulthood can lead to subclinical heart damage by middle age -- a condition that sets the stage for full-blown heart failure, according to findings of a federally funded study led by scientists at Johns Hopkins.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute on Aging

Contact: Ekaterina Pesheva
epeshev1@jhmi.edu
410-502-9433
Johns Hopkins Medicine

Public Release: 22-Jun-2015
Nature
Dual internal clocks keep plant defenses on schedule
Time management isn't just important for busy people -- it's critical for plants, too. A new study in the journal Nature shows how two biological clocks work together to help plants deal with intermittent demands such as fungal infections, while maintaining an already-packed daily schedule of activities like growth. The researchers also identified a gene that senses disturbances in the 'tick-tock' of one clock, and causes the other clock to tighten its timetable.
National Institutes of Health, US Department of Defense, Howard Hughes Medical Institute, Gordon and Betty Moore Foundation, Burroughs Wellcome Fund

Contact: Robin Ann Smith
ras10@duke.edu
919-681-8057
Duke University

Public Release: 22-Jun-2015
Journal of Theoretical Biology
Model could help counteract poisoning from popular painkiller
New research could help reverse deadly side effects caused by excessive doses of the drug acetaminophen, the major ingredient in Tylenol and many other medicines. Duke University researchers have developed a mathematical model of acetaminophen metabolism based on data from rats. The findings suggest that giving patients glutamine -- a common amino acid in the body -- alongside the standard antidote for acetaminophen overdose could prevent liver damage and boost the body's ability to recover.
National Science Foundation, National Institutes of Health

Contact: Robin Ann Smith
ras10@duke.edu
919-681-8057
Duke University

Public Release: 22-Jun-2015
Journal of Biological Chemistry
Researchers successfully target 'Achilles' heel' of MERS virus
Researchers studying the Middle East Respiratory Syndrome, or MERS, have found molecules that shut down the activity of an essential enzyme in the virus and could lead the way to better treatments for those infected. The team identified molecules that inhibit an enzyme essential to MERS virus replication, and also discovered a characteristic of the enzyme that is very different from other coronaviruses.
National Institutes of Health, Walther Cancer Foundation, US Department of Energy, Purdue Center for Cancer Research, Michigan Economic Development Corporation and Michigan Technology TriCorridor, Eli Lilly Company

Contact: Elizabeth K. Gardner
ekgardner@purdue.edu
765-494-2081
Purdue University

Public Release: 22-Jun-2015
Nature
Massachusetts General research team evolves CRISPR-Cas9 nucleases with novel properties
A team of Massachusetts General Hospital researchers has found a way to expand the use and precision of the powerful gene-editing tools called CRISPR-Cas9 RNA-guided nucleases. In their report receiving advance online release in Nature, the investigators describe evolved versions of the DNA-cutting Cas9 enzyme that are able to recognize a different range of nucleic acid sequences than is possible with the naturally occurring form of Cas9 that has been used to date.
National Institutes of Health, National Sciences and Engineering Research Council of Canada

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital

Public Release: 22-Jun-2015
Turning up the volume on prostate cancer
Rochester Institute of Technology professor Hans Schmitthenner is designing molecular imaging compounds that will selectively target prostate cancer cells and illuminate them with contrast dyes. An NIH grant is supporting the project and a team of undergraduate student researchers. The research is in the preclinical phase.
National Institutes of Health

Contact: Susan Gawlowicz
smguns@rit.edu
585-475-5061
Rochester Institute of Technology

Showing releases 126-150 out of 3760.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>

     
   

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