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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 126-150 out of 3572.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>

Public Release: 11-Dec-2014
Arthritis & Rheumatology
Nighttime gout attack risk more than 2 times higher than in the daytime
Novel research reveals that the risk of acute gout attacks is more than two times higher during the night or early morning hours than it is in the daytime. The study, published in Arthritis & Rheumatology, a journal of the American College of Rheumatology, confirms that nocturnal attacks persist even among those who did not consume alcohol and had a low amount of purine intake during the 24 hours prior to the gout attack.
National Institutes of Health, Arthritis Foundation, American College of Rheumatology Research and Education Fund

Contact: Dawn Peters

Public Release: 11-Dec-2014
Genes tell story of birdsong and human speech
A massive international effort to sequence and compare the entire genomes of 48 species of birds, representing every major order of the bird family tree, reveals that vocal learning evolved twice or maybe three times among songbirds, parrots and hummingbirds. Even more striking, the set of genes employed in each of those song innovations is remarkably similar to the genes involved in human speaking ability.
National Institutes of Health, National Science Foundation, Howard Hughes Medical Institute

Contact: Karl Leif Bates
Duke University

Public Release: 11-Dec-2014
Human DNA shows traces of 40 million-year battle for survival between primate and pathogen
Examination of DNA from 21 primate species -- from squirrel monkeys to humans -- exposes an evolutionary war against infectious bacteria over iron that circulates in the host's bloodstream. Supported by experimental evidence, these findings, published in Science on Dec. 12, demonstrate the vital importance of an increasingly appreciated defensive strategy called nutritional immunity. The study models an approach for uncovering reservoirs of genetic resistance to bacterial infections, knowledge that could be used to confront antibiotic-resistance and emerging diseases.
National Institutes of Health, Pew Cheritable Trusts

Contact: Julie Kiefer
University of Utah Health Sciences

Public Release: 11-Dec-2014
Developmental Cell
Senescent cells play an essential role in wound healing
Tumor suppressing senescent cells are bad for aging. The no-longer-dividing cells release a continual cascade of inflammatory factors and are implicated in many maladies including arthritis, atherosclerosis and late life cancer. But researchers show that senescent cells are good for wound healing -- identifying a single factor that causes them to promote that process. It's a crucial discovery for researchers working on developing treatments to clear senescent cells as a way to stem age-related disease.
American Italian Cancer Foundation, Japan Science and Technology Agency, National Institutes of Health, European Council

Contact: Kris Rebillot
Buck Institute for Age Research

Public Release: 11-Dec-2014
Journal of Pediatrics
Short sleep duration and sleep-related breathing problems increase obesity risk in kids
Sleep-related breathing problems and chronic lack of sleep may each double the risk of a child becoming obese by age 15, according to new research from Albert Einstein College of Medicine of Yeshiva University. The good news is that both sleep problems can be corrected. The study, which followed nearly 2,000 children for 15 years, published online today in The Journal of Pediatrics.
National Institutes of Health, UK Medical Research Council

Contact: Deirdre Branley
Albert Einstein College of Medicine

Public Release: 11-Dec-2014
53rd Annual American College of Neuropsychopharmacology Meeting
Early identification of modifiable risk factors for cognitive decline
Researchers now believe it's possible that risk factors for cognitive decline may show up long before diseases such as Alzheimer's develop. In a study presented at the American College of Neuropsychopharmacology annual meeting, scientists found that clues such as high blood pressure are often present in mid-life, and that identification and modification of such factors could prevent the progression of debilitating cognitive deficits later in life.
NIH/National Heart, Lung and Blood Institute, NIH/National Institute of Aging

Contact: Beth Miller
American College of Neuropsychopharmacology

Public Release: 11-Dec-2014
International team maps 'big bang' of bird evolution
The first findings of the Avian Phylogenomics Consortium are being reported nearly simultaneously in 29 papers -- eight papers in a Dec. 12 special issue of Science and 21 more in Genome Biology, GigaScience and other journals. The analyses suggest some remarkable new ideas about bird evolution, including insights into vocal learning and the brain, colored plumage, sex chromosomes and the birds' relationship to dinosaurs and crocodiles.
BGI and the China National GeneBank, National Institutes of Health, National Science Foundation, Howard Hughes Medical Institute, Lundbeck Foundation, Danish National Research Foundation, and others

Contact: Karl Bates
Duke University

Public Release: 10-Dec-2014
Research aims to improve hip and knee replacement success
Washington State University researchers are working to improve materials used in hip and knee replacements so that they last longer and allow patients to quickly get back on their feet after surgery. Led by Susmita Bose, professor in the School of Mechanical and Materials Engineering, the researchers have received a five-year, $1.8 million National Institutes of Health grant to improve the way bone implants integrate into the body.
National Institutes of Health

Contact: Susmita Bose
Washington State University

Public Release: 10-Dec-2014
UTHealth awarded $7.3 million for health information technology research
The University of Texas Health Science Center at Houston School of Biomedical Informatics has been awarded grants totaling $7.3 million to enhance health care and biomedical discovery through the use of health information technology.
NIH/National Library of Medicine, NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of General Medical Sciences

Contact: Robert Cahill
University of Texas Health Science Center at Houston

Public Release: 10-Dec-2014
Science Translational Medicine
Meniscus regenerated with 3-D printed implant
Researchers have devised a way to replace the knee's protective lining, called the meniscus, using a personalized 3-D printed implant, or scaffold, infused with human growth factors that prompt the body to regenerate the lining on its own. The therapy, successfully tested in sheep, could provide the first effective and long-lasting repair of damaged menisci, which occur in millions of Americans each year and can lead to debilitating arthritis. The paper was published today in the online edition of Science Translational Medicine.
National Institutes of Health, Arthroscopy Association of North America, American Orthopaedic Society for Sports Medicine, Harry M. Zweig Foundation

Contact: Karin Eskenazi
Columbia University Medical Center

Public Release: 10-Dec-2014
Science Translational Medicine
Myelin linked to speedy recovery of human visual system after tumor removal
An interdisciplinary team of neuroscientists and neurosurgeons from the University of Rochester has used a new imaging technique to show how the human brain heals itself in just a few weeks following surgical removal of a brain tumor.
NIH/National Institute of Neurological Disorders and Stoke, NIH/National Eye Institute

Contact: Monique Patenaude
University of Rochester

Public Release: 10-Dec-2014
Worms' mental GPS helps them find food
Salk scientists develop a theory to explain how animals gather information and switch attention.
National Science Foundation, University of California San Diego Institute, Rita Allen Foundation, National Institutes of Health, McKnight Endowment Fund, Ray Thomas Edwards Foundation

Contact: Salk Communications
Salk Institute

Public Release: 10-Dec-2014
Alcohol interferes with body's ability to regulate sleep
Researchers from the University of Missouri School of Medicine have found that drinking alcohol to fall asleep interferes with sleep homeostasis, the body's sleep-regulating mechanism.
NIH/National Institute of Alcohol Abuse and Alcoholism, Harry S. Truman Memorial Veterans' Hospital

Contact: Derek Thompson
University of Missouri-Columbia

Public Release: 10-Dec-2014
Chemical Research in Toxicology
New technology tracks carcinogens as they move through the body
Researchers for the first time have developed a method to track through the human body the movement of polycyclic aromatic hydrocarbons as extraordinarily tiny amounts of these potential carcinogens are biologically processed and eliminated.
Public Health Service, US Department of Energy, NIH/National Institute of General Medical Sciences

Contact: David Williams
Oregon State University

Public Release: 10-Dec-2014
Journal of Cardiac Failure
NYIT study: Thyroid hormones reduce animal cardiac arrhythmias
Rats that received thyroid hormones had a reduced risk for dangerous heart arrhythmias following a heart attack, according to a new study by a team of medical researchers at New York Institute of Technology. In the National Institutes of Health-funded study, published in the Journal of Cardiac Failure, the team found that thyroid hormone replacement therapy significantly reduced the incidence of atrial fibrillation -- a specific kind of irregular heartbeat, or arrhythmia -- in the rats, compared to a control group that did not receive the hormones.
National Institutes of Health

Contact: Elaine Iandoli
New York Institute of Technology

Public Release: 10-Dec-2014
New way to turn genes on
Using a gene-editing system originally developed to delete specific genes, MIT researchers have now shown that they can reliably turn on any gene of their choosing in living cells.
NIH/National Institute of Neurological Disorders & Stroke, Keck Foundation, Searle Scholars Foundation, Klingenstein Foundation, Vallee Foundation,Simons Foundation, Bob Metcalfe

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 10-Dec-2014
2014 San Antonio Breast Cancer Symposium
New drug combination for advanced breast cancer delays disease progression
A new combination of cancer drugs delayed disease progression for patients with hormone-receptor-positive metastatic breast cancer, according to a multi-center phase II trial. The findings of the randomized study were presented at the 2014 San Antonio Breast Cancer Symposium, held Dec. 6-9, by Kerin Adelson, M.D., assistant professor of medical oncology at Yale Cancer Center and chief quality officer at Smilow Cancer Hospital at Yale-New Haven.
NIH/National Cancer Institute, Millenium, Takeda Oncology Company

Contact: Vicky Agnew
Yale University

Public Release: 10-Dec-2014
56th American Society of Hematology Annual Meeting
Patients given less blood during transfusions do well
It's a simple premise -- now backed up by more evidence than ever: 'Why give more blood to anyone if you can't show it benefits them?' Jeffrey Carson of Rutgers Robert Wood Johnson Medical School has found that for many patients, smaller blood transfusions after surgery are at least as beneficial as larger ones, both in the short term and the long term. His study is published in The Lancet.
NIH/National Heart, Lung, and Blood Institute

Contact: Rob Forman
Rutgers University

Public Release: 10-Dec-2014
Proceedings of the National Academy of Sciences
Next-generation treatment for urinary tract infections may focus on fitness genes
Ask any woman: Urinary tract infections are painful and unpredictable. University of Michigan researchers identify genes to help fight the infections that are becoming resistant to antibiotics.
NIH/National Institute of Diabetes and Digestive and Kidney Disease

Contact: Shantell Kirkendoll
University of Michigan Health System

Public Release: 10-Dec-2014
Proceedings of the National Academy of Sciences
Testosterone may contribute to colon cancer tumor growth
James Amos-Landgraf, an assistant professor of veterinary pathobiology in the MU College of Veterinary Medicine, found evidence suggesting that the male hormone testosterone may actually be a contributing factor in the formation of colon cancer tumors.
National Institutes of Health, American Cancer Society

Contact: Nathan Hurst
University of Missouri-Columbia

Public Release: 10-Dec-2014
Heath Research Education, Clinical Rehabilitation
CWRU nursing school develops how-to exercise pamphlet for people with MS
Fatigue and pain, along with other symptoms, prevent many people with multiple sclerosis from exercising. But a new how-to guide for a home-based exercise program, tested by researchers at Case Western Reserve University's nursing school and the Lerner Research Institute at the Cleveland Clinic, offers a way for people with MS to stay more physically active.
NIH/Eunice Kennedy Shriver National Institute of Child Health & Development, NIH/National Institute of Nursing Research

Contact: Susan Griffith
Case Western Reserve University

Public Release: 10-Dec-2014
Nature Chemical Biology
CWRU scientists find key to vitamin A metabolism
Researchers have discovered the mechanism that enables the enzyme Lecithin: retinol acyltransferase to store vitamin A, which is essential for sight. The researchers hope the new information will be used to design small molecule therapies for degenerative eye diseases. The same enzymatic activity of LRAT that allows specific cells to absorb vitamin A can be used to transport small molecule drugs to the eye.
National Institutes of Health, US Department of Energy

Contact: Kevin Mayhood
Case Western Reserve University

Public Release: 10-Dec-2014
Can poor sleep lead to dementia?
People who have sleep apnea or spend less time in deep sleep may be more likely to have changes in the brain that are associated with dementia, according to a new study published in the December 10, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.
NIH/National Institute on Aging, Alzheimer's Association, Hawaii Community Foundation

Contact: Rachel Seroka
American Academy of Neurology

Public Release: 10-Dec-2014
Antimicrobial Agents and Chemotherapy
Drug developed at Pitt proves effective against antibiotic-resistant 'superbugs'
A treatment pioneered at the University of Pittsburgh Center for Vaccine Research is far more effective than traditional antibiotics at inhibiting the growth of drug-resistant bacteria, including so-called 'superbugs' resistant to almost all existing antibiotics, which plague hospitals and nursing homes. The findings provide a needed boost to the field of antibiotic development, which has been limited in the last four decades and outpaced by the rise of drug-resistant bacterial strains.
National Institutes of Health, University of Pittsburg

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 10-Dec-2014
Proteins stepping on 'landmines': How they survive the immense heat they create
Research from Indiana University-Purdue University Indianapolis and the University of California Berkeley published online on Dec. 10 in Nature reports on how some proteins survive extreme heat generated when they catalyze reactions.
National Institutes of Health, US Department of Energy, National Science Foundation

Contact: Cindy Fox Aisen
Indiana University-Purdue University Indianapolis School of Science

Showing releases 126-150 out of 3572.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>


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