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Showing releases 126-150 out of 3343. << < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>
Public Release: 9-May-2013
Cell
Mapping the embryonic epigenome
A large, multi-institutional research team involved in the NIH Epigenome Roadmap Project has published a sweeping analysis in the current issue of the journal Cell of how genes are turned on and off to direct early human development. The study is led by Bing Ren of the Ludwig Institute for Cancer Research, Joseph Ecker of The Salk Institute for Biological Studies and James Thomson of the Morgridge Institute for Research.
Ludwig Institute for Cancer Research, NIH/Epigenome Roadmap Project, and others
Contact: Rachel Steinhardt
Rsteinhardt@licr.org
212-450-1582
Ludwig Institute for Cancer Research
Public Release: 9-May-2013
Social Science & Medicine
Obese students' childbearing risk varies with high school obesity rates
For young women in high school, the risk of childbearing may depend on the prevalence of obesity in their schools, according to sociologists, who found that as the prevalence of obesity rises in a school, so do the odds of obese high school students bearing children.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development
Contact: Matthew Swayne
mls29@psu.edu
814-865-9481
Penn State
Public Release: 9-May-2013
Psychological Science
Social connections drive the 'upward spiral' of positive emotions and health
People who experience warmer, more upbeat emotions may have better physical health because they make more social connections, according to a new study published in Psychological Science, a journal of the Association for Psychological Science.
NIH/National Institute of Mental Health
Contact: Anna Mikulak
amikulak@psychologicalscience.org
202-293-9300
Association for Psychological Science
Public Release: 9-May-2013
USF gets $2.8M NIH grant with Aetna to study genetic testing and breast cancer treatment
The University of South Florida (Tampa, FL) and Aetna are launching a groundbreaking study that will examine the influence genetic testing may have on clinical treatment decisions among breast cancer patients and their doctors. The national collaborative study is supported by a $2.8 million grant from the National Institutes of Health.
National Institutes of Health
Contact: Anne DeLotto Baier
abaier@health.usf.edu
813-974-3303
University of South Florida (USF Health)
Public Release: 9-May-2013
Science
Heady mathematics
Two UC Berkeley applied mathematicians have found a way to mathematically describe the evolution and disappearance of a foam. Using these equations, they were able to generate a movie that shows the complex draining, popping and rearrangement of these bubbles as the foam vanishes.
US Department of Energy, National Science Foundation, NIH/National Cancer Institute
Contact: Robert Sanders
rlsanders@berkeley.edu
510-643-6998
University of California - Berkeley
Public Release: 9-May-2013
Cell Reports
Scientists show how nerve wiring self-destructs
Many medical issues affect nerves, from injuries and chemotherapy to glaucoma and multiple sclerosis. The common theme in these scenarios is destruction of nerve axons, the long wires that transmit signals to other parts of the body. Researchers at Washington University School of Medicine in St. Louis have found a way the body can remove injured axons, identifying a potential target for new drugs that could prevent the inappropriate loss of axons.
American-Italian Cancer Foundation, European Molecular Biology Organization, Muscular Dystrophy Association, National Institutes of Health
Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine
Public Release: 9-May-2013
Molecular Cell
Studies generate comprehensive list of genes required by innate system to defend sex cells
Investigators from Cold Spring Harbor Laboratory today publish studies revealing many previously unknown components of an innate system that defends sex cells -- the carriers of inheritance across generations -- from the ravages of transposable genetic elements.
National Institutes of Health, Howard Hughes Medical Institute, T and V Stanley
Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory
Public Release: 9-May-2013
Cell
Dad's genome more ready at fertilization than mom's is -- but hers catches up
Researchers from Huntsman Cancer Institute at the University of Utah have discovered that while the genes provided by the father arrive at fertilization pre-programmed to the state needed by the embryo, the genes provided by the mother are in a different state and must be reprogrammed to match.
Howard Hughes Medical Institute, Huntsman Cancer Foundation, NIH/National Cancer Institute
Contact: Linda Aagard
801-587-7639
University of Utah Health Sciences
Public Release: 9-May-2013
PLOS Computational Biology
Early infant growth rate linked to composition of gut microbiota
The composition of gut microbiota in a new-born baby's gut has been linked to the rate of early infant growth, reports research published this week in PLOS Computational Biology. The findings support the assertion that the early development of "microbiota" -- the body's microbial ecosystem -- in an infant can influence growth and thereby the likelihood of obesity.
Norwegian Research Council, NIH/Intramural Research Program
Contact: Merete Eggesbø
merete.eggesbo@fhi.no
Public Library of Science
Public Release: 8-May-2013
Environmental Science & Technology
Study finds PCB concentrations same in urban and rural areas
Despite the expectation of a large environmental exposure difference, UI researchers report that mothers and children in East Chicago, Ind., and Researchers at the University of Iowa report that residents in a rural area in Iowa have the same PCB levels in their blood as residents in urbanized East Chicago. Results appear in the journal Environmental Science & Technology.
National Institutes of Health, US Department of Educaiton
Contact: Richard Lewis
richard-c-lewis@uiowa.edu
319-384-0012
University of Iowa
Public Release: 8-May-2013
Journal of Infectious Diseases
New malaria tool shows which kids at greatest risk
Researchers at Michigan State University have identified a test that can determine which children with malaria are likely to develop cerebral malaria, a much more life-threatening form of the disease. The screening tool could be a game-changer in resource-limited rural health clinics where workers see hundreds of children with malaria each day and must decide which patients can be sent home with oral drugs and which need to be taken to hospitals for more comprehensive care.
National Institutes of Health
Contact: Andy McGlashen
andy.mcglashen@cabs.msu.edu
517-355-5158
Michigan State University
Public Release: 8-May-2013
Cancer Prevention Research
Soy and tomato combo may be effective in preventing prostate cancer
Tomatoes and soy foods may be more effective in preventing prostate cancer when they are eaten together than when either is eaten alone, said a University of Illinois study.
"We used mice that were genetically engineered to develop an aggressive form of prostate cancer. Even so, half the animals that had consumed tomato and soy had no cancerous lesions in the prostate at study's end," said John Erdman, a U of I professor of nutrition.
NIH/National Cancer Institute, National Institutes of Health
Contact: Phyllis Picklesimer
p-pickle@illinois.edu
217-244-2827
University of Illinois College of Agricultural, Consumer and Environmental Sciences
Public Release: 8-May-2013
Brain Structure and Function
Brain anatomy of dyslexia is not the same in men and women, boys and girls
Using MRI, neuroscientists have found significant differences in brain anatomy when comparing men and women with dyslexia to their non-dyslexic control groups. Their study is the first to directly compare brain anatomy of females with and without dyslexia. "Females have been overlooked…. Our research suggests that we need to tackle dyslexia in each sex separately to address questions about its origin and potentially, treatment," says Guinevere Eden, director, Center for the Study of Learning, Georgetown.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH/National Center for Advancing Translational Sciences, National Science Foundation
Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center
Public Release: 8-May-2013
Journal of Neuroscience
Enhanced motion perception in autism may point to an underlying cause of the disorder
Children with autism see simple movement twice as quickly as other children their age, and this hypersensitivity to motion may provide clues to a fundamental cause of the developmental disorder, according to a new study.
National Institutes of Health
Contact: Susan Hagen
susan.hagen@rochester.edu
585-276-4061
University of Rochester
Public Release: 8-May-2013
Pediatric Research
Carnitine supplement may improve survival rates of children with heart defects
A common nutritional supplement may be part of the magic in improving the survival rates of babies born with heart defects, researchers report.
National Institutes of Health, Foundation Leducq, American Heart Association
Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University
Public Release: 8-May-2013
Journal of Immunology
Discovery shows fat triggers rheumatoid arthritis
Scientists have discovered that fat cells in the knee secrete a protein linked to arthritis, a finding that paves the way for new gene therapies that could offer relief and mobility to millions of people worldwide.
National Institutes of Health, NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
Contact: David Kelly
david.kelly@ucdenver.edu
303-724-7903
University of Colorado Denver
Public Release: 8-May-2013
New England Journal of Medicine
Mass. General, Duke study identifies 2 genes that combine to cause rare syndrome
Researchers from Massachusetts General Hospital and Duke University have identified genetic mutations that appear to underlie a rare but devastating syndrome combining reproductive failure with cerebellar ataxia -- a lack of muscle coordination -- and dementia. In a paper that will appear in the New England Journal of Medicine the investigators describe finding mutations in one or both of two genes involved in a cellular process called ubiquitination in affected members of five unrelated families.
NIH/National Institute for Child Health and Human Development, National Institutes of Health
Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
Public Release: 8-May-2013
Statistical Methods in Medical Research
Cancer biorepository speeds clinical trials, drug development, Moffitt analysis shows
Researchers at Moffitt Cancer Center say identifying and selecting participants for phase II cancer clinical trials from a centralized warehouse of patient-donated biological data expedites participant accrual, reduces trial size, saves money, and may speed test drugs through the drug development pipeline.
NIH/National Cancer Institute
Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute
Public Release: 8-May-2013
Breast Cancer Research and Treatment
Fun and friends help ease the pain of breast cancer
Breast cancer patients who say they have people with whom they have a good time, or have "positive social interactions" with, are better able to deal with pain and other physical symptoms, according to a new Kaiser Permanente study published today in Breast Cancer Research and Treatment.
National Institutes of Health, NIH/National Cancer Institute
Contact: Jacqueline Brown
jacqueline.brown@golinharris.com
415-318-4361
Kaiser Permanente
Public Release: 8-May-2013
Nature
Lucky bacteria strike it rich during formation of treatment-resistant colonies
Like pioneers in search of a better life, bacteria on a surface wander around and often organize into highly resilient communities, known as biofilms. It turns out that a lucky few bacteria become the elite cells that start the colonies, and they organize in a rich-get-richer pattern similar to the distribution of wealth in the US economy, according to a new study by researchers at UCLA, Northwestern University and the University of Washington.
National Institutes of Health, National Science Foundation, Cystic Fibrosis Foundation
Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University
Public Release: 8-May-2013
BMJ Quality and Safety
Nurse staffing ratios affect hospital readmissions for children with common conditions
A new study shows that pediatric nurse staffing ratios are significantly associated with hospital readmission for children with common medical and surgical conditions. The study, led by a nurse scientist at Cincinnati Children's Hospital Medical Center, is believed to be the first to examine the extent to which hospital nurse staffing levels are related to pediatric readmissions.
Agency for Healthcare Research and Quality, NIH/National Institute for Nursing Research
Contact: Jim Feuer
jim.feuer@cchmc.org
513-636-4656
Cincinnati Children's Hospital Medical Center
Public Release: 8-May-2013
New England Journal of Medicine
Discovery of gene mutation causing Sturge-Weber syndrome, port-wine stain birthmarks offers new hope
In new findings published in the New England Journal of Medicine (Epub ahead of print), researchers from the Kennedy Krieger Institute reveal the discovery of the cause -- a genetic mutation that occurs before birth -- of Sturge-Weber syndrome (SWS) and port-wine stain birthmarks. SWS is a rare disorder affecting approximately one in 20,000 births, while port-wine birthmarks are more common, affecting approximately one million individuals in the United States.
Hunter's Dream for a Cure Foundation, NIH/Brain Vascular Malformation Consortium
Contact: Megan Lustig
mlustig@spectrumscience.com
202-955-6222
Kennedy Krieger Institute
Public Release: 8-May-2013
Nature
Immune cells that suppress genital herpes infections identified
Fred Hutchinson Cancer Research Center and University of Washington scientists have identified a class of immune cells that reside long-term in the genital skin and mucosa and are believed to be responsible for suppressing recurring outbreaks of genital herpes.
National Institutes of Health, James B. Pendleton Charitable Trust
Contact: Dean Forbes
dforbes@fhcrc.org
206-667-2896
Fred Hutchinson Cancer Research Center
Public Release: 8-May-2013
Journal of Clinical Investigation
Gene replacement in pigs ameliorates cystic fibrosis-associated intestinal obstruction
In this issue of the Journal of Clinical Investigation, Michael Welsh and colleagues at the University of Iowa demonstrate that transgenic expression of normal CFTR in the intestine of CF pigs alleviated meconium ileus.
National Institutes of Health, Cystic Fibrosis Foundation, Gilead Sciences
Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Public Release: 8-May-2013
Journal of Clinical Investigation
Differences between 'marathon mice' and 'couch potato mice' reveal key to muscle fitness
Using "marathon" and "couch potato" mouse models, researchers at Sanford-Burnham Medical Research Institute discovered that microRNAs link the defining characteristics of fit muscles: The abilities to burn fuel and switch between muscle fiber types. They also found that active people have higher levels of one microRNA than sedentary people.
National Institutes of Health, American Heart Association
Contact: Deborah Robison
drobison@sanfordburnham.org
407-615-0072
Sanford-Burnham Medical Research Institute
Showing releases 126-150 out of 3343. << < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>
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