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Showing releases 126-150 out of 613 releases.
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Public Release: 21-Oct-2009

Neuroscience 2009
Damaging inflammatory response could hinder spinal cord repair
The inflammatory response following a spinal cord injury appears to be set up to cause extra tissue damage instead of promoting healing, new research suggests. Scientists analyzing this inflammatory response in mice discovered that the types of cells recruited to the site of the injury are dominated within a week by those that promote inflammation. When chronic, inflammation can prevent healing, and these inflammatory cells are believed to remain at the injury site indefinitely.

NIH/National Institute of Neurological Disorders and Stroke
Contact: Phil Popovich
phillip.popovich@osumc.edu
614-688-8576
Ohio State University
Public Release: 21-Oct-2009

Neuroscience 2009
Amphetamine use in adolescence may impair adult working memory
Rats exposed to high doses of amphetamines at an age that corresponds to the later years of human adolescence display significant memory deficits as adults -- long after the exposure ends, researchers report.

NIH/National Institute of Child Health and Human Development
Contact: Diana Yates
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign
Public Release: 21-Oct-2009
 Science Translational Medicine
Pitt/NIH team find way to protect healthy cells from radiation damage
Researchers at the University of Pittsburgh School of Medicine and the National Cancer Institute, may be hot on the heels of a Holy Grail of cancer therapy: they have found a way to not only protect healthy tissue from the toxic effects of radiation treatment, but also increase tumor death. The findings appear today in Science Translational Medicine.

NIH/National Cancer Institute, Howard Hughes Medical Institute
Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences
Public Release: 21-Oct-2009
 Nature
Study shows how normal cells influence tumor growth
A new study led by Ohio State University cancer researchers shows for the first time that the loss of a gene called PTEN from a type of normal cell in breast tumors can dramatically change the environment within the tumor in ways that foster the tumor's growth.

NIH/National Cancer Institute, Komen Breast Cancer Foundation, Evelyn Simmers Charitable Trust, Terry Fox New Frontiers Group Grant, Natural Science and Engineering Research Council of Canada
Contact: Darrell E. Ward
darrell.ward@osumc.edu
614-293-3737
Ohio State University Medical Center
Public Release: 21-Oct-2009
Kaiser Permanente launches first clinical trial for obese women to control pregnancy weight
The "Healthy Moms" clinical trial is the first to help obese women control weight during pregnancy. The Kaiser Permanente study trial challenges current national guidelines that suggest all pregnant women should gain weight.
This is the first study trial to test a weight maintenance program and weekly support groups for obese pregnant women.
Excess pregnancy weight can lead to preeclampsia, diabetes, overweight babies, C-sections, birth injuries and weight retention after pregnancy.

NIH/National Institute of Child Health and Human Development
Contact: Danielle Cass
danielle.x.cass@kp.org
510-267-5354
Kaiser Permanente
Public Release: 21-Oct-2009

Neuroscience 2009
Tailoring physical therapy can restore more functions after neurological injury
New research suggests a tailored approach to physical therapy after a neurological injury such as a stroke, traumatic brain injury or spinal cord injury could help restore a wider variety of functions.

NIH/National Institute of Child Health and Human Development
Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Public Release: 20-Oct-2009
UF receives $12.2 million to establish national network of scientists
During the next two years, researchers from seven institutions will implement a new type of networking system that eventually will link scientists across the country and world to like-minded peers and potential collaborators.

NIH/National Center for Research Resources
Contact: April Frawley Birdwel
afrawley@ufl.edu
352-273-5817
University of Florida
Public Release: 20-Oct-2009
 Journal of General Internal Medicine
Cancer survivors may not be getting the help they need to stop smoking
More than a quarter of cancer survivors who still smoke have not been advised to quit smoking by their health care providers in the last year, according to a study published by researchers at Fox Chase Cancer Center. Their findings suggest that health care providers -- from doctors to dentists to nurses -- are missing an opportunity to make a dramatic difference in the quality of life of their patients.

NIH/National Cancer Institute
Contact: Greg Lester
gregory.lester@fccc.edu
215-728-2753
Fox Chase Cancer Center
Public Release: 19-Oct-2009
 Proceedings of the National Academy of Sciences
Detecting the undetectable in prostate cancer screening
Northwestern University researchers, using an extremely sensitive tool based on nanotechnology, have detected previously undetectable levels of prostate-specific antigen (PSA) in patients who have undergone radical prostatectomy. With technology 300 times more sensitive than commercially available PSA tests, the researchers found measureable PSA levels in each post-operative patient in its study. After the removal of the prostate gland, patients typically have PSA levels that are undetectable when measured using conventional diagnostic tools.

NIH/National Cancer Institute
Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University
Public Release: 19-Oct-2009
 Proceedings of the National Academy of Sciences
MIT neuroscientists find neural stopwatch in the brain
MIT researchers have identified populations of neurons that code time with extreme precision in the primate brain. These neurons are found in two interconnected brain regions, the prefrontal cortex and the striatum, both of which are known to play critical roles in learning, movement, and thought control.

NIH/National Eye Institute, National Parkinson Foundation, Alfred P. Sloan Foundation, Penn State University
Contact: Jen Hirsch
jfhirsch@mit.edu
617-253-1682
Massachusetts Institute of Technology
Public Release: 19-Oct-2009
 Environmental Health Perspectives
Study finds mercury levels in children with autism and those developing typically are the same
In a large population-based study published online today, researchers at the UC Davis MIND Institute report that after adjusting for a number of factors, typically developing children and children with autism have similar levels of mercury in their blood streams.

NIH/National Institute of Environmental Health Sciences, US Environmental Protection Agency, UC Davis MIND Institute
Contact: Phyllis Brown
phyllis.brown@ucdmc.ucdavis.edu
916-734-9023
University of California - Davis - Health System
Public Release: 19-Oct-2009

Neuroscience 2009
Understanding the brain's natural foil for over-excited neurons
Glutamate is to the brain like coffee is to our bodies. A cup of Joe in the morning can wake us, but overloading on caffeine causes the stimulant to work against us.

NIH/National Institute of Neurological Disorders and Stroke
Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Public Release: 18-Oct-2009
 Nature Genetics
New chromosomal abnormality identified in leukemia associated with Down syndrome
Researchers identified a new chromosomal abnormality in acute lymphoblastic leukemia that appears to work in concert with another mutation to give rise to cancer. This latest anomaly is particularly common in children with Down syndrome.

NIH/National Cancer Institute, Bear Necessities Pediatric Research Foundation, Children's Cancer Research Foundation, National Institutes of Health, American-Lebanese-Syrian Associated Charities
Contact: Summer Freeman
summer.freeman@stjude.org
901-595-3061
St. Jude Children's Research Hospital
Public Release: 16-Oct-2009
ICU patients on ventilators flex and stretch in study at Case Western Reserve University
Few people have thought about providing an exercise workout in the intensive care unit, especially for patients on ventilators -- even those who are comatose -- but a researcher from Frances Payne Bolton School of Nursing at Case Western Reserve University will be doing some bedside coaching and exercising to get patients stretching and flexing their muscles.

NIH/National Institute of Nursing Research
Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University
Public Release: 15-Oct-2009
 Nature Genetics
Loss of tumor-suppressor and DNA-maintenance proteins causes tissue demise
A study published in the October issue of Nature Genetics demonstrates that loss of the tumor-suppressor protein p53, coupled with elimination of the DNA-maintenance protein ATR, severely disrupts tissue maintenance in mice. As a result, tissues deteriorate rapidly, which is generally fatal in these animals. In addition, the study provides supportive evidence for the use of inhibitors of ATR in cancer therapy.

NIH/National Institute on Aging, Abramson Family Cancer Research Institute
Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Public Release: 15-Oct-2009
NeuroAIDS is target of federal grant to Children's Hospital
A $6 million, five-year federal grant to the Children's Hospital of Philadelphia will enable researchers to investigate a novel approach in treating HIV infection -- a unique class of drugs focused on developing therapies for psychological and neurological effects in AIDS. At the heart of the program are drugs that target the neurokinin-1 receptor in human immune cells. The researchers will test the drug's antiviral activity as well as potential benefits in relieving depression-like symptoms.

NIH/National Institute of Mental Health
Contact: John Ascenzi
Ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia
Public Release: 15-Oct-2009
$4 million NCI grant funds comparative effectiveness research at Southwest Oncology Group
New CANCERGEN center's vision is to make Southwest Oncology Group a national leader in cancer comparative effectiveness research.

NIH/National Cancer Institute
Contact: Frank DeSanto
fdesanto@umich.edu
734-998-0114
University of Michigan Health System
Public Release: 15-Oct-2009
UNC scientists win $1.6 million stimulus award to accelerate decoding of human genome
UNC's Morgan Giddings, Ph.D., and Xian Chen, Ph.D., have been awarded a $1.6 million two-year "Grand Opportunities" grant from the National Human Genome Research Institute to accelerate this research. Their effort will be part of a consortium of investigators studying the human genome blueprint, titled the "ENCyclopedia Of DNA Elements." The consortium's overall goal is to assemble a comprehensive catalog of functional elements in the human genome.

NIH/National Human Genome Research Institute
Contact: Les Lang
llang@med.unc.edu
919-966-9366
University of North Carolina School of Medicine
Public Release: 15-Oct-2009
ResearchToolkit.org provides 1-stop Web resource for health researchers
Group Health Research Institute; University of Washington, Institute of Translational Health Sciences; Duke Translational Medicine Institute; and Wayne State University have developed a new Web site to help researchers create and sustain successful multisite research collaborations. The project team created the site to enhance the efficiency of research from start to finish, including developing research networks, launching and managing projects, and sharing study results or other products such as data sets, tools and training resources.

NIH/National Center for Research Resources
Contact: Rebecca Hughes
hughes.r@ghc.org
206-287-2055
Group Health Cooperative Center for Health Studies
Public Release: 15-Oct-2009
 Science
Rare procedure documents how the human brain computes language
A study by researchers at the University of California, San Diego School of Medicine reports a significant breakthrough in explaining gaps in scientists' understanding of human brain function. The study -- which provides a picture of language processing in the brain with unprecedented clarity -- will be published in the Oct. 16 issue of the journal Science.

NIH/National Institute of Neurological Disorders and Stroke, National Institutes of Health, Mental Illness and Neuroscience Discovery Institute at Harvard University, Weill Medical College
Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego
Public Release: 15-Oct-2009
 Cell
Stretching the Golgi: a link between form and function
A research team at the University of California, San Diego School of Medicine has provided a surprisingly simple explanation for the mechanism and features of the "Golgi apparatus" -- a structure that has baffled generations of scientists. The model developed by the UC San Diego scientists suggests that the Golgi's unusual shape is a direct consequence of the way it works.

NIH/National Institute of Diabetes and Digestive and Kidney Diseases, American Cancer Society Fellowship, Burroughs Wellcome Fund, V Foundation, NIH New Innovator Award
Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego
Public Release: 14-Oct-2009
MSU becoming center of excellence for Parkinson's research
A team of researchers from Michigan State University and the University of Cincinnati have been awarded a $6.2 million Morris K. Udall Center of Excellence for Parkinson's disease grant.

NIH/National Institute for Neurological Disorders and Stroke
Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Public Release: 14-Oct-2009
 PLoS ONE
New research reveals 41 percent increase in children's short stay hospital admissions
The number of children being admitted to hospitals in England for short stays increased by 41 percent between 1996 and 2006, according to research published in PLoS One today. The authors of the study, from Imperial College London, say this increase may be linked to a shortfall in out-of-hours primary care services, but further research is needed before they can draw any firm conclusions.

NIH/National Institutes for Health Research
Contact: Lucy Goodchild
lucy.goodchild@imperial.ac.uk
44-020-759-46702
Imperial College London
Public Release: 13-Oct-2009
 Nature Molecular Systems Biology
Mathematical modeling correctly predicts previously unknown biological mechanism of regulation
A team of scientists, led by a biomedical engineer at The University of Texas at Austin, have demonstrated – for the first time – that mathematical models created from data obtained by DNA microarrays, can be used to correctly predict previously unknown cellular mechanisms. This brings biologists a step closer to one day being able to understand and control the inner workings of the cell as readily as NASA engineers plot the trajectories of spacecraft today.

NIH/National Human Genome Research Institute, National Science Foundation, American Institute for Mathematics and Cancer Research
Contact: Becky Rische
brische@mail.utexas.edu
512-471-7272
University of Texas at Austin
Public Release: 13-Oct-2009
NIH funds new virus database at UT Southwestern
The National Institutes of Health has awarded a $15.7 million contract to UT Southwestern Medical Center and Northrop Grumman Corp. to develop an open-access national online database and analysis resource center that will help scientists study and combat viruses such as those that cause hepatitis, encephalitis, smallpox, acute respiratory distress and dengue fever, as well as newly emerging pathogenic viruses.

NIH/National Institute of Allergy and Infectious Diseases
Contact: Kristen Holland Shear
Kristen.hollandshear@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Showing releases 126-150 out of 613 releases.
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