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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 126-150 out of 3620.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>

Public Release: 18-Mar-2015
JAMA Psychiatry
Are antipsychotic drugs more dangerous to dementia patients than we think?
Drugs aimed at quelling the behavior problems of dementia patients may also hasten their deaths more than previously realized, a new study finds. The research adds more troubling evidence to the case against antipsychotic drugs as a treatment for the delusions, hallucinations, agitation and aggression that many people with Alzheimer's disease and other dementias experience.
NIH/National Institute of Mental Health, NIH/National Institute on Aging

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 18-Mar-2015
Journal of the American Heart Association
Cardiometabolic risk factors harden arteries early in Mexican-Americans
Metabolically unhealthy Mexican-Americans showed signs of early atherosclerosis. Metabolic profile, including blood sugar, insulin resistance and blood pressure, may be a stronger indicator of early atherosclerosis than obesity in Mexican-Americans.
Center for Clinical and Translational Sciences, NIH/National Center for Advancing Translational Sciences

Contact: Akeem Ranmal
t-akeem.ranmal@heart.org
214-706-1755
American Heart Association

Public Release: 18-Mar-2015
New England Journal of Medicine
MSU doctors' discovery of how malaria kills children will lead to life-saving treatments
In a groundbreaking study published in the New England Journal of Medicine, Michigan State University's Dr. Terrie Taylor and her team discovered what causes death in children with cerebral malaria, the deadliest form of the disease. Taylor and her research team found that the brain becomes so swollen it is forced out through the bottom of the skull and compresses the brain stem. This pressure causes the children to stop breathing and die.
National Institutes of Health

Contact: Kim Ward
kim.ward@cabs.msu.edu
517-432-0117
Michigan State University

Public Release: 18-Mar-2015
Science Translational Medicine
Penn researchers describe new approach to promote regeneration of heart tissue
The heart tissue of mammals has limited capacity to regenerate after an injury such as a heart attack, in part due to the inability to reactivate a cardiac muscle cell and proliferation program. A team has now shown that a subset of microRNAs is important for cardiomyocyte cell proliferation during development and is sufficient to induce proliferation in cardiomyocytes in the adult heart.
NIH/National Heart, Lung, and Blood Institute

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 18-Mar-2015
New England Journal of Medicine
MSU doctors' discovery of how malaria kills children will lead to life-saving treatments
In a groundbreaking study published in the New England Journal of Medicine, Michigan State University's Dr. Terrie Taylor and her team discovered what causes death in children with cerebral malaria, the deadliest form of the disease.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Scott Willyerd
Scott@dickjones.com
724-260-0198
Dick Jones Communications

Public Release: 17-Mar-2015
Nature Structural & Molecular Biology
3-D snapshot of protein highlights potential drug target for breast cancer
One of 15 different polymerases tasked with copying our genetic material, POLQ is singled out in this study for its unique role -- captured in an X-ray crystallography visual -- in DNA repair pathways linked to breast cancer, and therefore, potential as a drug target.
National Institutes of Health, Cancer Prevention and Research Institute of Texas, Grady F. Saunders, Ph.D., Distinguished Research Professorship, NIH/National Cancer Institute, NIH/National Institute of General Medical Sciences

Contact: Jennifer Nachbur
jennifer.nachbur@med.uvm.edu
802-656-7875
University of Vermont

Public Release: 17-Mar-2015
Biological Chemistry
A pinch of baking soda for better vision?
A new study from the Makino Laboratory at Massachusetts Eye and Ear/Harvard Medical School and colleagues at Salus University, describes how bicarbonate also alters how we see by modifying the visual signal generated by rod and cone photoreceptors that detect light. This study is described online in the Journal of Biological Chemistry.
NIH/National Eye Institute, Research to Prevent Blindness, Howe Laboratory Endowment of Massachusetts Eye and Ear

Contact: Mary Leach
Mary_Leach@meei.harvard.edu
Massachusetts Eye and Ear Infirmary

Public Release: 17-Mar-2015
Neuron
UTSW neuroscientists identify cell type in the brain that controls body clock circadian rhythms
UT Southwestern Medical Center neuroscientists have identified key cells within the brain that are critical for determining circadian rhythms, the 24-hour processes that control sleep and wake cycles, as well as other important body functions such as hormone production, metabolism, and blood pressure.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Gregg Shields
gregg.shields@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 17-Mar-2015
PLOS Medicine
HIV not as infectious soon after transmission as thought
People who recently have been infected with HIV may not be as highly infectious as previously believed, a finding that could improve global efforts to prevent HIV transmission and save lives. In particular, the finding bolsters the strategy of treating patients with antiretroviral drugs before the onset of AIDS to prevent transmission.
National Institutes of Health, James S. McDonnell Foundation

Contact: Christine Sinatra
512-471-4641
University of Texas at Austin

Public Release: 17-Mar-2015
First in human nanotherapy brain cancer trial launched at CTRC
A CTRC neurosurgeon used a tiny catheter to insert radioactive liposomes, only 100 nanometers across, into the stubborn tumor in David Williams' brain. The therapy, developed at the CTRC in San Antonio, offers hope to those suffering from the most devastating brain cancers, and could be expanded to treat other types of cancer as well.
NIH/National Cancer Institute, CTRC Foundation, Cancer Prevention and Research Institute of Texas

Contact: Elizabeth Allen
allenea@uthscsa.edu
210-450-2020
University of Texas Health Science Center at San Antonio

Public Release: 17-Mar-2015
JAMA
Genetic markers play role in who benefits from aspirin, NSAIDs to lower colon cancer risk
An Indiana University cancer researcher and her colleagues have identified genetic markers that may help determine who benefits from regular use of aspirin and other nonsteroidal anti-inflammatory drugs for lowering one's risk of developing colorectal cancer.
National Institutes of Health

Contact: Michael Schug
maschug@iupui.edu
317-278-0953
Indiana University

Public Release: 17-Mar-2015
Clinical Cancer Research
Macrophages may play critical role in melanoma resistance to BRAF inhibitors
Researchers at The Wistar Institute have discovered one way in which melanoma becomes resistant to a particular form of targeted therapy, and understanding this phenomenon may lead to a new melanoma target or prompt new designs of these treatments.
National Institutes of Health, Commonwealth Universal Research Enhancement Program of the Pennsylvania Department of Health, The Wistar Institute Intramural Grants

Contact: Ben Leach
bleach@wistar.org
215-495-6800
The Wistar Institute

Public Release: 17-Mar-2015
GW researchers receive $6.2 million NIH program project grant to research pediatric dysphagia
An interdisciplinary group of researchers from the George Washington University School of Medicine and Health Sciences and Children's National Health System has been awarded a program project grant for $6.2 million from the Eunice Kennedy Shriver National Institute of Child Health and Human Development to solve pediatric dysphagia -- a chronic difficulty with feeding and swallowing in children.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University

Public Release: 17-Mar-2015
Journal of Economic Perspectives
Study: Prices of cancer drugs have soared since 1995
The prices of leading cancer drugs have risen at rates far outstripping inflation over the last two decades, according to a new study co-authored by an MIT economist -- but the exact reasons for the cost increases are unclear.
NIH/National Cancer Institute

Contact: Abby Abazorius
abbya@mit.edu
617-253-2709
Massachusetts Institute of Technology

Public Release: 17-Mar-2015
Endocrinology
New compound prevents type 1 diabetes in animal models -- before it begins
Scientists from the Florida campus of The Scripps Research Institute have successfully tested a potent synthetic compound that prevents type 1 diabetes in animal models of the disease.
National Institutes of Health, National Research Service Award

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 17-Mar-2015
International Journal of Cancer
Microenvironment provides growth factor for metastasis
When a person has cancer that spreads to the bone and bone marrow, the tissue becomes increasingly fragile, often leading to increased bone resorption. In a surprising discovery, investigators at Children's Hospital Los Angeles found that when neuroblastoma cells metastasize to the bone, there initially occurs an increase in bone deposition, not resorption. They also determined that this process is driven by a chemical messenger called VEGFA.
National Institutes of Health, Ruth L. Kirschstein National Research Service Award

Contact: Ellin Kavanagh
ekavanagh@chla.usc.edu
323-361-7628
Children's Hospital Los Angeles

Public Release: 17-Mar-2015
PLOS Medicine
New model finds HIV acute phase infectivity may be lower than previously estimated
Previous calculations may have overestimated the importance of HIV transmission from recently infected individuals ('acute phase infectivity') in driving HIV epidemics, according to an article published by Steve Bellan of the University of Texas at Austin, and colleagues in this week's PLOS Medicine.
J.S. McDonnell Foundation, NIH/National Institute of General Medical Sciences

Contact: Maya Sandler
medicinepress@plos.org
PLOS

Public Release: 17-Mar-2015
Antimicrobial Agents and Chemotherapy
Joint fluid harbors bacterial clumps after replacement despite pre-surgery antibiotics
Researchers from Thomas Jefferson University and NIH tested for prophylactic antibiotic concentrations in joint fluid samples after joint replacements.
National Institutes of Health

Contact: Gail Benner
gail.benner@jefferson.edu
215-955-2240
Thomas Jefferson University

Public Release: 17-Mar-2015
JAMA
The link between aspirin, NSAIDs and colon cancer prevention may hinge on genetic variations
The link between taking aspirin, non-steroidal anti-inflammatory drugs, or NSAIDS, and colorectal cancer prevention is well established, but the mechanisms behind the protective effect have not been understood. A new study, co-led by investigators at Fred Hutchinson Cancer Research Center and published March 17 in JAMA, suggests this protection differs according to variations in DNA.
NIH/National Cancer Institute, National Institutes of Health, US Department of Health and Human Services

Contact: Kristen Woodward
kwoodwar@fredhutch.org
206-667-5095
Fred Hutchinson Cancer Research Center

Public Release: 17-Mar-2015
Anesthesiology
Study reveals previously unknown site of anesthetic action
Anesthetics have been used in surgical procedures for more than 150 years, but the mechanisms by which inhaled anesthesia actually work are poorly understood. Now, researchers at Johns Hopkins Medicine have discovered that anesthetics bind to and interfere with certain proteins in excitatory neurons, which are necessary for these neurons to transmit signals involved in anesthesia and the perception of pain.
National Institutes of Health

Contact: Marin Hedin
mhedin2@jhmi.edu
410-502-9429
Johns Hopkins Medicine

Public Release: 17-Mar-2015
JAMA
Genetic background determines whether aspirin/NSAIDS will reduce colorectal cancer risk
An analysis of genetic and lifestyle data from 10 large epidemiologic studies confirmed that regular use of aspirin or NSAIDs appears to reduce the risk of colorectal cancer in most individuals but also found that a few individuals with rare genetic variants do not share this benefit.
NIH/National Cancer Institute, NIH/National Institute for Diabetes and Digestive and Kidney Diseases

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Public Release: 17-Mar-2015
Alcoholism: Clinical & Experimental Research
Socioeconomic status moderates genetic and environmental influences on alcohol use
A new study has examined genetic and environmental influences underlying alcohol use. Results show that genetic effects on the amount of alcohol use appear to be greater in low socioeconomic-status (SES) conditions. Shared environmental effects tended to increase in high-SES conditions, and non-shared environmental effects tended to decrease with SES.
John D. and Catherine T. MacArthur Foundation Research Network on Successful Midlife Development, NIH/National Institute on Aging

Contact: Nayla Hamdi, M.A.
hamdi002@umn.edu
617-388-5435
Alcoholism: Clinical & Experimental Research

Public Release: 17-Mar-2015
Alcoholism: Clinical & Experimental Research
Identifying how drinking contexts and youth characteristics change over time
Certain contexts are associated with specific negative drinking-related outcomes. A new study examines associations between drinking contexts and youth characteristics over time. Findings indicate that where youth drink alcohol varies by age, gender, smoking, and deviant behaviors.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Sharon Lipperman-Kreda
skreda@prev.org
510-883-5750
Alcoholism: Clinical & Experimental Research

Public Release: 16-Mar-2015
ECS Journal of Solid State Science and Technology
'Additive manufacturing' could greatly improve diabetes management
Using a process similar to ink jet printing, engineers have created an improved type of glucose sensor for people with type 1 diabetes. It will be part of an 'artificial pancreas' system that should work better, cost less and be more comfortable, and may find use by diabetic patients around the world.
National Institutes of Health

Contact: Greg Herman
greg.herman@oregonstate.edu
541-737-2496
Oregon State University

Public Release: 16-Mar-2015
Nature Reviews Immunology
Investigators find window of vulnerability for STIs to infect female reproductive tract
Dartmouth researchers have presented a comprehensive review of the role of sex hormones in the geography of the female reproductive tract and evidence supporting a 'window of vulnerability' to HIV and other sexually transmitted infections.
National Institutes of Health

Contact: Kirk Cassels
Kirk.A.Cassels@Hitchcock.org
603-653-6177
The Geisel School of Medicine at Dartmouth

Showing releases 126-150 out of 3620.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>

     
   

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