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Showing releases 151-175 out of 3304. << < 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 > >>
Public Release: 17-Jul-2013
Risk Analysis
Maize trade disruption could have global ramifications
Disruptions to US exports of maize could pose food security risks for many US trade partners due to the lack of trade among other producing and importing nations, says a Michigan State University study.
National Institutes of Health
Contact: Layne Cameron
layne.cameron@cabs.msu.edu
517-353-8819
Michigan State University
Public Release: 17-Jul-2013
Nature
Scripps Research Institute scientists find 3D structure of key drug target for diabetes
An international team led by scientists at The Scripps Research Institute has determined and analyzed the three-dimensional atomic structure of the human glucagon receptor. The receptor, found mainly on liver and kidney cells, helps regulate glucose levels in the bloodstream and is the target of potential therapeutic agents for type 2 diabetes.
NIH/National Institute of Health, Chinese Ministry of Health, Shanghai Science and Tech., Development Fund, and others
Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute
Public Release: 17-Jul-2013
Cell Host & Microbe
New way to target an old foe: Malaria
A team led by MIT researchers has now developed a way to grow liver tissue that can support the liver stage of the life cycle of the two most common species of malaria, Plasmodium falciparum and Plasmodium vivax.
Bill & Melinda Gates Foundation, Medicines for Malaria Venture, NIH/National Institute of Allergy and Infectious Diseases, National Institutes of Health, Howard Hughes Medical Institute
Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology
Public Release: 17-Jul-2013
Science Translational Medicine
Empty decoys divert antibodies from neutralizing gene therapy in cell, animal studies
Gene therapy researchers have produced a bioengineered decoy that fools the immune system and prevents it from mistakenly defeating the benefits delivered by a corrective gene. The decoy was effective in animal studies, and if the approach succeeds in humans, it offers a potential new treatment for genetic diseases such as hemophilia, while advancing the broader field of gene therapy.
National Institutes of Health, Howard Hughes Medical Institute
Contact: John Ascenzi
Ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia
Public Release: 17-Jul-2013
Nature
UMMS scientists show proof-of-principal for silencing extra chromosome responsible for Down syndrome
Scientists at the University of Massachusetts Medical School are the first to establish that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the extra chromosome responsible for trisomy 21, also known as Down syndrome, a genetic disorder characterized by cognitive impairment. The discovery provides the first evidence that the underlying genetic defect responsible for Down syndrome can be suppressed in cells in culture.
NIH/National Institute of General Medical Sciences
Contact: Jim Fessenden
james.fessenden@umassmed.edu
508-856-2000
University of Massachusetts Medical School
Public Release: 17-Jul-2013
Nature
Keeping the reserve force home
Hematopoietic stem cells -- bone marrow-derived adult stem cells that give rise to the wide variety of specialized blood cells -- come in two flavors: the reserve force sits quietly waiting to be called upon while the active arm continually proliferates spawning billions of blood cells every day. In their latest study, researchers at the Stowers Institute for Medical Research reveal a new mechanism that is critical in maintaining the delicate balance between the two.
Stowers Institute, Ministry of Science and Technology of India, National Institutes of Health
Contact: Gina Kirchweger
gxk@stowers.org
816-806-1036
Stowers Institute for Medical Research
Public Release: 17-Jul-2013
Journal of American College of Cardiology
Exercise, endurance sports increase arryhthmia and heart failure risk in carriers of ARVD/C mutation
A Johns Hopkins study finds that healthy people who carry a genetic mutation for arrhythmogenic right ventricular dysplasia/cardiomyopathy are at much higher risk of developing the symptoms of the life-threatening heart disease if they participate in endurance sports and frequent exercise. The study also suggests that those carriers who significantly cut back on their exercise regimen may reduce their risk or delay the onset of symptoms.
NIH/National Heart, Lung, and Blood Institute, St. Jude Medical Foundation, Medtronic Inc.
Contact: Ellen Beth Levitt
elevitt2@jhmi.edu
410-955-5307
Johns Hopkins Medicine
Public Release: 16-Jul-2013
Proceedings of the National Academy of Sciences
Researchers step closer to custom-building new blood vessels
Researchers at Johns Hopkins have coaxed stem cells into forming networks of new blood vessels in the laboratory, then successfully transplanted them into mice. The stem cells are made by reprogramming ordinary cells, so the new technique could potentially be used to make blood vessels genetically matched to individual patients and unlikely to be rejected by their immune systems, the investigators say.
American Heart Association, NIH/National Heart, Lung, and Blood Institute, NIH/National Cancer Institute, National Science Foundation
Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine
Public Release: 16-Jul-2013
Nature Cell Biology
Molecular relative of p53 tumor suppressor protein also helps cancer cells thrive
The protein TAp73 is a relative of the well-known, tumor-suppressor protein p53, yet it is still not known whether TAp73 enhances tumor cell growth and, if so, exactly how. Penn researchers found that TAp73 supports the proliferation of human and mouse tumor cells. They also identify an important mechanism by which TAp73 gives tumor cells a growth advantage: it activates the expression of an enzyme important for cell replications and antioxidant protection.
NIH/National Cancer Institute, US Department of Defense
Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Public Release: 16-Jul-2013
Research leads to affordable technology to fight mosquito-borne diseases
Technology that hampers mosquitoes' host-seeking behavior, identified at the University of California, Riverside in 2011, has led to the development of the world's first product that blocks mosquitoes' ability to efficiently detect carbon dioxide, their primary method of tracking human blood meals.
Bill and Melinda Gates Foundation, National Institutes of Health
Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside
Public Release: 16-Jul-2013
Circulation: Heart Failure
MS drug shows promise for preventing heart failure
A drug already approved to treat multiple sclerosis may also hold promise for treating cardiac hypertrophy, or thickening of the cardiac muscle -- a disorder that often leads to heart failure, researchers at the University of Illinois at Chicago College of Medicine report.
National Institutes of Health, Medical Research Council, University of Illinois at Chicago
Contact: Sharon Parmet
sparmet@uic.edu
312-413-2695
University of Illinois at Chicago
Public Release: 16-Jul-2013
Proceedings of the National Academy of Sciences
Ecological forces structure your body's personal mix of microbes
Environmental conditions have a stronger influence on the mix of microbes living in your body than does competition between species. Instead of excluding each other, microbes that fiercely compete for similar resources are more likely to cohabit the same individual. The findings are a step toward building a predictive model of the human microbiome to study how medical conditions change this massive biological system, identify how to promote beneficial microbiomes, and design interventions for hard-to-manage problems like chronic digestive inflammation.
National Science Foundation, Alfred P. Sloan Foundation, National Institutes of Health
Contact: Leila Gray
leilag@uw.edu
206-685-0381
University of Washington
Public Release: 16-Jul-2013
Small
Steering stem cells with magnets
By feeding stem cells tiny particles made of magnetized iron oxide, scientists can then use magnets to attract the cells to a particular location in the body.
NIH/National Heart Lung and Blood Institute
Contact: Quinn Eastman
qeastma@emory.edu
404-727-7829
Emory Health Sciences
Public Release: 16-Jul-2013
STI & AIDS World Congress
Ex-offender data shows high risk of sexually transmitted infections after release
The American health care system may be missing a golden opportunity to curtail STIs in communities, according to a new study of offenders following release from the justice system. Researchers at Indiana University School of Medicine and Regenstrief Institute presented findings at the STI & AIDS World Congress in Vienna this week showing that individuals released from the justice system have a high risk of contracting a sexually transmitted infection within the first year.
NIH/National Institute of Allergy and Infectious Diseases
Contact: Mary Hardin
mhardin@iu.edu
317-274-5456
Indiana University
Public Release: 16-Jul-2013
Fertility and Sterility
Distinctive brain blood flow patterns associated with sexual dysfunction
Premenopausal women who aren't interested in sex and are unhappy about this reality have distinctive blood flow patterns in their brains in response to explicit videos compared to women with normal sexual function, researchers report.
National Institutes of Health
Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University
Public Release: 16-Jul-2013
Journal of General Internal Medicine
People with pre-diabetes who drop substantial weight may ward off type 2 diabetes
People with pre-diabetes who lose roughly 10 percent of their body weight within six months of diagnosis dramatically reduce their risk of developing type 2 diabetes over the next three years, according to results of research led by Johns Hopkins scientists.
NIH/National Center for Research Resources
Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine
Public Release: 16-Jul-2013
Biomaterials
Duke bioengineers develop new approach to regenerate back discs
Cell therapies may stop or reverse the pain and disability of degenerative disc disease and the loss of material between vertebrae, according to Duke University scientists.
National Institutes of Health
Contact: Richard Merritt
richard.merritt@duke.edu
919-660-8414
Duke University
Public Release: 16-Jul-2013
Advanced Drug Discovery Reviews
Mathematical models target disease with drugs chosen by your DNA
Medicines that are personally tailored to your DNA are becoming a reality, thanks to the work of US and Chinese scientists who developed statistical models to predict which drug is best for a specific individual with a specific disease.
NIH/National Center for Advancing Translational Sciences
Contact: Victoria M. Indivero
vmi1@psu.edu
814-865-9481
Penn State
Public Release: 16-Jul-2013
Journal of Molecular Diagnostics
RNA diagnostic test from paraffin improves lung cancer diagnosis over routine microscopic evaluation
Scientists at the Universities of North Carolina and Utah have developed a histology expression predictor for the most common types of lung cancer: adenocarcinoma, carcinoid, small cell carcinoma and squamous cell carcinoma. This predictor can confirm histologic diagnosis in routinely collected paraffin samples of patients' tumors and can complement and corroborate pathologists' findings.
NIH/National Cancer Institute, Thomas G. Labreque Foundation, Joan's Legacy Foundation
Contact: Dianne Shaw
dgs@med.unc.edu
919-966-7834
University of North Carolina Health Care
Public Release: 16-Jul-2013
Alzheimer's Association International Conference
Highest risk Alzheimer's genetic carriers take positive steps after learning risk status
People who found out they carried an uncommon genetic risk for Alzheimer's disease did not experience more anxiety, depression or distress than non-carriers, and were more active in efforts to reduce their risk of Alzheimer's disease -- by exercising, eating a healthy diet and taking recommended vitamins and medications -- report researchers from the Perelman School of Medicine at the University of Pennsylvania today at the 2013 Alzheimer's Association International Conference.
National Institutes of Health
Contact: Kim Menard
kim.menard@uphs.upenn.edu
215-662-6183
University of Pennsylvania School of Medicine
Public Release: 16-Jul-2013
Radiology
Fat in organs and blood may increase risk of osteoporosis
A new study has found that obese people with higher levels of fat in their liver, muscle tissue and blood also have higher amounts of fat in their bone marrow, putting them at risk for osteoporosis.
National Institutes of Health
Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Public Release: 15-Jul-2013
NIH grant lets Virginia Tech's X.J. Meng study how hepatitis E virus infects across species barrier
X.J. Meng, a University Distinguished Professor at Virginia Tech and a virologist at the Virginia-Maryland Regional College of Veterinary Medicine, has received a four-year, nearly $1.6 million grant from the National Institutes of Health to better understand the genetic elements that allow hepatitis E virus to transfer from animals to people.
National Institutes of Health
Contact: Sherrie R. Whaley
srwhaley@vt.edu
540-231-7911
Virginia Tech
Public Release: 15-Jul-2013
Proceedings of the National Academy of Sciences
Chemical compound shows promise as alternative to opioid pain relievers
A drug targeting a protein complex containing two different types of opioid receptors may be an effective alternative to morphine and other opioid pain medications, without any of the side effects or risk of dependence, according to research led by the Icahn School of Medicine at Mount Sinai.
NIH/National Institute on Drug Abuse
Contact: Mount Sinai Press Office
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Public Release: 15-Jul-2013
Nature Structural and Molecular Biology
Scientists construct visual of intracellular 'zip code' signaling linked to learning, memory
New University of Vermont research provides a rare "picture" of the activity taking place at the single molecular level: visual evidence of the mechanisms involved when a cell transports mRNA (or messenger RNA) to where a protein is needed to perform a cellular function.
National Institutes of Health
Contact: Jennifer Nachbur
jennifer.nachbur@uvm.edu
802-656-7875
University of Vermont
Public Release: 15-Jul-2013
Proceedings of the National Academy of Sciences
Fear factor: Missing brain enzyme leads to abnormal levels of fear in mice, reveals new research
A little bit of learned fear is a good thing, keeping us from making risky, stupid decisions or falling over and over again into the same trap. But new research from neuroscientists and molecular biologists at USC shows that a missing brain protein may be the culprit in cases of severe over-worry, where the fear perseveres even when there's nothing of which to be afraid.
NIH/National Institute of Mental Health, NIH/National Institute of Child Health and Human Development
Contact: Suzanne Wu
suzanne.wu@usc.edu
213-740-0252
University of Southern California
Showing releases 151-175 out of 3304. << < 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 > >>
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