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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 151-175 out of 3609.

<< < 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 > >>

Public Release: 13-Mar-2015
Molecular Cancer Research
Nodal alone does not produce anti-cancer effects
In a new study, standard treatments for metastatic melanoma are not effective against a growth factor protein called Nodal.
National Institutes of Health, NIH/National Cancer Institute, Eisenberg Research Scholar, Robert Kris Family

Contact: Peggy Murphy
Ann & Robert H. Lurie Children's Hospital of Chicago

Public Release: 13-Mar-2015
Clinical Cancer Research
Genetically engineered immunotoxin shows early promise in patients with B-cell malignancies
DT2219, a new bispecific ligand-directed diphtheria toxin, was found to be safe and clinically effective in a small group of patients with relapsed/refractory B-cell malignancies, according to phase I clinical trial data.
National Institutes of Health, Randy Shaver Foundation, Lions Children's Cancer Fund, William Lawrence and Blanche Hughes Foundation

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 12-Mar-2015
Case Western Reserve scientists find hidden meaning and 'speed limits' within genetic code
Case Western Reserve scientists have discovered that speed matters when it comes to how messenger RNA deciphers critical information within the genetic code -- the complex chain of instructions critical to sustaining life. The investigators' findings, which appear in the March 12 journal Cell, give scientists critical new information in determining how best to engage cells to treat illness -- and, ultimately, keep them from emerging in the first place.
National Institutes of Health

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 12-Mar-2015
NIH awards UC biologist $1.9 million for genetic research
An additional award of over $500,000 from the National Science Foundation will explore why animals lose traits over time, and how that might apply to loss of skin pigmentation in humans.
National Institutes of Health, National Science Foundation

Contact: Dawn Fuller
University of Cincinnati

Public Release: 12-Mar-2015
Cell Stem Cell
Boosting a natural protection against Alzheimer's disease
Researchers at the University of California, San Diego School of Medicine have identified a gene variant that may be used to predict people most likely to respond to an investigational therapy under development for Alzheimer's disease. The study, published March 12 in Cell Stem Cell, is based on experiments with cultured neurons derived from adult stem cells.
California Institute of Regenerative Medicine, A.P. Gianinni Foundation for Medical Research, BrightFocus Foundation, National Institutes of Health

Contact: Scott LaFee
University of California - San Diego

Public Release: 12-Mar-2015
American Journal of Clinical Nutrition
High cholesterol, triglycerides can keep vitamin E from reaching body tissues
In the continuing debate over how much vitamin E is enough, a new study has found that high levels of blood lipids such as cholesterol and triglycerides can keep this essential micronutrient tied up in the blood stream, and prevent vitamin E from reaching the tissues that need it. This raises new questions about whether or not most people have an adequate intake of vitamin E.
USDA Agricultural Research Service, National Institutes of Health

Contact: Maret Traber
Oregon State University

Public Release: 12-Mar-2015
Study bolsters 'turbocharged' protein as a promising tool in hemophilia gene therapy
Using gene therapy to produce a mutant human protein with unusually high blood-clotting power, scientists have successfully treated dogs with the bleeding disorder hemophilia, without triggering an unwanted immune response. In addition, the 'turbocharged' clotting factor protein eliminated pre-existing antibodies that often weaken conventional treatments for people with hemophilia.
NIH/National Institutes of Health, National Blood Foundation

Contact: John Ascenzi
Children's Hospital of Philadelphia

Public Release: 12-Mar-2015
Journal of American College of Surgeons
Liver-sparing operation associated with higher survival rates in cancer patients
A surgical approach in which a surgeon removes less than a lobe of the liver in a patient undergoing an operation for liver cancer is associated with lower mortality and complication rates, according to new study results published online as an 'article in press' in the Journal of the American College of Surgeons.
NIH/National Cancer Institute Cancer Center

Contact: Sally Garneski
American College of Surgeons

Public Release: 12-Mar-2015
Nature Communications
A 'warhead' molecule to hunt down deadly bacteria
Boston College chemist Jianmin Gao and researchers in his lab report they achieved selective modification of two common lipids, producing a new bio-chemical method to label deadly bacteria and potentially target them with antibiotics with reduced harm to healthy cells, according to a new report in Nature Communications.
NIH/National Institute of General Medical Studies, National Science Foundation

Contact: Ed Hayward
Boston College

Public Release: 12-Mar-2015
You are when you eat
A new study finds that limiting flies to specific eating hours protected their hearts against aging.
National Institutes of Health, American Heart Association, H.A. and Mary K. Chapman Trust, Bert and Ethel Aginsky Research Scholar Awards, Leona M. and Harry B Helmsley Charitable Trust, Glenn Center for Aging

Contact: Natalia Elko
San Diego State University

Public Release: 12-Mar-2015
Teen cannabis users have poor long-term memory in adulthood
Teens who were heavy marijuana users -- smoking it daily for about three years -- had an abnormally shaped hippocampus and performed poorly on long-term memory tasks, reports a new study. The hippocampus is important to long-term memory, which is the ability to remember life events. The brain abnormalities and memory problems were observed during the individuals' early twenties, two years after they stopped smoking marijuana.
National Institutes of Health

Contact: Marla Paul
Northwestern University

Public Release: 12-Mar-2015
Preventing heart cells from turning to bone
Researchers from the Gladstone Institutes have used human cells to discover how blood flow in the heart protects against the hardening of valves in cardiovascular disease. What's more, they've identified a potential way to correct this process when it goes wrong by flipping the switch on just a handful of genes. These findings may have implications for related conditions, like hardening of the arteries, which causes heart attacks and stroke.
NIH/National Heart, Lung, and Blood Institute, Progenitor Cell Biology Consortium, LK Whittier Foundation, William Younger Family Foundation, Eugene Roddenberry Foundation, and others

Contact: Dana Smith
Gladstone Institutes

Public Release: 12-Mar-2015
Optogenetics without the genetics
Light can be used to activate normal, non-genetically modified neurons through the use of targeted gold nanoparticles, report scientists from the University of Chicago and the University of Illinois at Chicago. The new technique, described in the journal Neuron on March 12, represents a significant technological advance with potential advantages over current optogenetic methods, including possible use in the development of therapeutics toward diseases such as macular degeneration.
National Institutes of Health, Beckman Initiative for Macular Research, Research to Prevent Blindness

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 12-Mar-2015
Reaching '80 percent by 2018' would prevent more than 20,000 colorectal cancer deaths per year
Increasing colorectal cancer screening rates to 80 percent by 2018 would prevent an additional 21,000 colorectal cancer deaths per year by 2030, according to a new study.
NIH/National Cancer Institute, American Cancer Society

Contact: David Sampson
American Cancer Society

Public Release: 12-Mar-2015
Inflammatory factor IL-3 may play essential role in development of sepsis
A new study finds that Interleukin-3, an inflammatory factor most associated with allergic reactions, has an important role in the overwhelming, life-threatening immune reaction called sepsis. Massachusetts General Hospital investigators found that the presence of IL-3 is essential to the development of sepsis in a mouse model and that IL-3 levels in human patients with sepsis are higher in those at greater risk of dying.
National Institutes of Health, German Research Foundation, Société Française d'Anesthésie-Réanimation, Institut Servier, Fondation Groupe Pasteur Mutualité, Fulbright Program

Contact: Sue McGreevey
Massachusetts General Hospital

Public Release: 12-Mar-2015
Molecule-making machine simplifies complex chemistry
A new molecule-making machine could do for chemistry what 3-D printing did for engineering: Make it fast, flexible and accessible to anyone. Chemists at the University of Illinois built the machine to assemble complex small molecules at the click of a mouse, like a 3-D printer at the molecular level. The automated process has the potential to greatly speed up and enable new drug development and other technologies that rely on small molecules.
National Institutes of Health

Contact: Liz Ahlberg
University of Illinois at Urbana-Champaign

Public Release: 12-Mar-2015
Major chemistry advances reported in Science by REVOLUTION Medicines founder
REVOLUTION Medicines Inc. today announced the publication of new research by the company's scientific founder Martin D. Burke, M.D., Ph.D., professor of chemistry, University of Illinois at Urbana-Champaign, and Early Career Scientist of the Howard Hughes Medical Institute. The paper in the journal Science demonstrates the automation and robust application of a unified 'building blocks' approach for synthesizing multiple classes of complex natural chemicals that could be valuable backbones for new medicines.
National Institutes of Health, National Science Foundation, Howard Hughes Medical Institute, Bristol-Myers Squibb

Contact: Katie Engleman
Pure Communications Inc.

Public Release: 12-Mar-2015
Increased susceptibility to measles a side effect of Ebola epidemic
Johns Hopkins Bloomberg School of Public Health researchers say that major disruptions in the health care systems in West Africa caused by the Ebola crisis have led to significant decreases in vaccinations for childhood diseases, increasing susceptibility to measles and other vaccine-preventable illnesses.
Bill and Melinda Gates Foundation, US Department of Homeland Security Science & Technology Directorate, DHS/RAPIDD Program, National Institutes of Health, NIH/National Institute of Allergy and Infectious Diseases

Contact: Stephanie Desmon
Johns Hopkins University Bloomberg School of Public Health

Public Release: 11-Mar-2015
Translational Psychiatry
Rat brains point to lead's role in schizophrenia
A study of the brains of rats exposed to lead has uncovered striking similarities with what is known about the brains of human schizophrenia patients, adding compelling evidence that lead is a factor in the onset of schizophrenia. Results of the study by scientists at Columbia University's Mailman School of Public Health appear in the journal Translational Psychiatry.
NIH/National Institute of Environmental Health Sciences

Contact: Tim Paul
Columbia University's Mailman School of Public Health

Public Release: 11-Mar-2015
Women's Health Issues
Could yoga lessen prenatal depression?
A community-based prenatal yoga program may be an acceptable, safe, and effective intervention to reduce the symptoms of depression among pregnant women, according to initial results from a small pilot study. The results suggest that further research is warranted, the authors said.
NIH/National Institute of Mental Health

Contact: David Orenstein
Brown University

Public Release: 11-Mar-2015
Developmental Cell
Scientists find a new beta cell maturation step triggered by weaning from milk to chow
Scientists have discovered a new developmental step in the process of beta cell maturation, triggered by the dietary transition from milk to chow. The findings indicate that transitioning from fat-rich milk to carbohydrate-rich food enhances beta cells' ability to secrete insulin in response to glucose, and allows glucose to stimulate beta cell replication. The researchers plan to study whether early weaning affects mice and humans' chances of developing diabetes.
National Institutes of Health, Juvenile Diabetes Research Organization, European Research Council (ERC), Helmsley Charitable Trust, DON Foundation, BIRAX, I-CORE Program of the Israel Science Foundation

Contact: Dov Smith
The Hebrew University of Jerusalem

Public Release: 11-Mar-2015
Journal of Clinical Endocrinology & Metabolism
Babies' body mass index may predict childhood obesity
Body mass index (BMI) during infancy may help to predict if a child will be obese by age four. In a study cohort having a majority of African-American children, researchers said that a better understanding of intant growth patterns may lead to more effective early efforts at obesity prevention.
National Institutes of Health

Contact: John Ascenzi
Children's Hospital of Philadelphia

Public Release: 11-Mar-2015
Addictive Behaviors
Gender and race influences when teens start drinking, smoking and doing drugs
Cigarette use among white teenagers is substantially higher than among black and Hispanic teenagers, especially at 18 years old, according to Penn State researchers.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH/National Institute on Drug Abuse, NIH/National Cancer Institute

Contact: Victoria M. Indivero
Penn State

Public Release: 11-Mar-2015
Journal of Clinical Investigation
Finding strengths -- and weaknesses -- in hepatitis C's armor
Using a specially selected library of different hepatitis C viruses, a team of researchers led by Johns Hopkins scientists has identified tiny differences in the pathogens' outer shell proteins that underpin their resistance to antibodies. The findings, reported in the January 2015 issue of the Journal of Clinical Investigation, suggest a reason why some patients' immune systems can't fend off hepatitis C infections, and they reveal distinct challenges for those trying to craft a successful vaccine to prevent them.
National Institutes of Health

Contact: Lauren Nelson
Johns Hopkins Medicine

Public Release: 11-Mar-2015
Drug restores brain function and memory in early Alzheimer's disease
An existing epilepsy drug appears to reverse a condition in elderly patients who are at high risk for dementia due to Alzheimer's disease.
National Institutes of Health

Contact: Jill Rosen
Johns Hopkins University

Showing releases 151-175 out of 3609.

<< < 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 > >>


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