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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 151-175 out of 3646.

<< < 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 > >>

Public Release: 6-Apr-2015
Proceedings of the National Academy of Sciences
Device extracts rare tumor cells using sound
A simple blood test may one day replace invasive biopsies thanks to a new device that uses sound waves to separate blood-borne cancer cells from white blood cells. Carnegie Mellon University President Subra Suresh and fellow researchers from the Massachusetts Institute of Technology and The Pennsylvania State University report the latest advancement that brings their device one step closer to clinical use in a paper published this week in the online early edition of the Proceedings of the National Academy of Sciences.
National Institutes of Health, Penn State Center for Nano Scale Science, National Science Foundation

Contact: Jocelyn Duffy
jhduffy@andrew.cmu.edu
412-268-9982
Carnegie Mellon University

Public Release: 6-Apr-2015
Nature
New target for anticancer drugs: RNA
Messenger RNAs -- the working copies of genes that are used to assemble proteins -- have typically been ignored as drug targets because they all look about the same. But UC Berkeley researchers have found that a subset of mRNAs -- many of which have been linked to cancer -- have unique tags. These short RNA tags bind to a protein, eIF3, that regulates translation at the ribosome, making the binding site a promising target for anticancer drugs.
NIH/National Institute of General Medical Sciences

Contact: Robert Sanders
rlsanders@berkeley.edu
510-643-6998
University of California - Berkeley

Public Release: 6-Apr-2015
Journal of Clinical Oncology
A third of breast cancer patients concerned about genetic risk
A new study from the University of Michigan Comprehensive Cancer Center finds that many women diagnosed with breast cancer are concerned about the genetic risk of developing other cancers themselves or of a loved one developing cancer.
NIH/National Cancer Institute, American Cancer Society

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 6-Apr-2015
Nature Biotechnology
Pulling the strings of our genetic puppetmasters
Researchers have developed a new method to activate genes by synthetically creating a key component of the epigenome that controls how our genes are expressed. The new technology allows researchers to turn on specific gene promoters and enhancers -- pieces of our genomes that control our genes' activity -- by chemically manipulating proteins that package our DNA.
National Institutes of Health, National Science Foundation

Contact: Ken Kingery
ken.kingery@duke.edu
919-660-8414
Duke University

Public Release: 6-Apr-2015
Pediatrics
Young guns: Study finds high firearm violence rate in high-risk youth after assault injury
Two young men sit in an inner-city emergency room. One is getting care for injuries he suffered in a fight, the other, for a sore throat. After getting care, both head back out to an environment of violence and poverty. But, a new study finds, the one who had been in a fight will have a nearly 60 percent chance of becoming involved in a violent incident involving a firearm within the next two years.
NIH/National Institute on Drug Abuse, NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 6-Apr-2015
Health Affairs
Emergency rooms see rising rate of patients with chronic conditions, lower rate of injuries
The rate of emergency department visits in California for non-injuries has risen while the rate of visits for injuries has dropped, according to a new study led by University of California San Francisco that documents the increasing amount of care provided in emergency departments for complex, chronic conditions.
California HealthCare Foundation, National Center for Advancing Translational Sciences, National Institutes of Health, UCSF Clinical & Translational Science Institute, Robert Wood Johnson Foundation

Contact: Elizabeth Fernandez
elizabeth.fernandez@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 6-Apr-2015
JAMA Internal Medicine
Lower extremity revascularization not effective in majority of nursing home residents
Only a few US nursing home residents who undergo lower extremity revascularization procedures are alive and ambulatory a year after surgery, according to UCSF researchers, and most patients still alive gained little, if any, function.
NIH/National Institute on Aging, Paul B. Beeson Clinical Scientist Development Award in Agin, UCSF Claude D. Pepper Older Americans Independence Center

Contact: Scott Maier
scott.maier@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 6-Apr-2015
Annals of Internal Medicine
Physical therapy, surgery produce same results for stenosis in older patients
Pitt researchers find equal outcomes in a two-year study, but policy issues may lurk underneath lumbar spinal stenosis issues.
National Institutes of Health, NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Chuck Finder
FinderCE@upmc.edu
412-996-5852
University of Pittsburgh Schools of the Health Sciences

Public Release: 6-Apr-2015
Circulation: Journal of the American Heart Association
Physically active middle-aged adults have low risk of sudden cardiac arrest
The incidence of sudden cardiac arrest during sports activities is relatively low among physically active middle-aged adults. Education and preventive measures can further lower risk of sports-related sudden cardiac death in middle-aged adults.
NIH/National Heart, Lung, and Blood Institute

Contact: Akeem Ranmal
t-akeem.ranmal@heart.org
214-706-1755
American Heart Association

Public Release: 6-Apr-2015
Annals of Internal Medicine
Few commercial weight-loss programs show evidence of effectiveness, Johns Hopkins reports
In a bid to help physicians guide obese and overweight patients who want to try a commercial weight-loss program, a team of Johns Hopkins researchers reviewed 4,200 studies for solid evidence of their effectiveness but concluded only a few dozen of the studies met the scientific gold standard of reliability
NIH/National Heart, Lung and Blood Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, JHU-UMD Diabetes Research Center, Dean's Office Summer Research Funding

Contact: Heather Dewar
hdewar1@jhmi.edu
410-502-9463
Johns Hopkins Medicine

Public Release: 3-Apr-2015
PLOS ONE
UCLA research links HIV to age-accelerating cellular changes
People undergoing treatment for HIV-1 have an increased risk for earlier onset of age-related illnesses such as some cancers, renal and kidney disease, frailty, osteoporosis and neurocognitive disease. But is it because of the virus that causes AIDS or the treatment? New research suggests that HIV itself accelerates these aging related changes by more than 14 years.
NIH/National Institute on Aging grant, UCLA AIDS Institute/CFAR seed grant from the National Institutes of Health, NIH T032 training grant, National Science Foundation grant

Contact: Enrique Rivero
erivero@mednet.ucla.edu
310-794-2273
University of California - Los Angeles Health Sciences

Public Release: 3-Apr-2015
Science Advances
Targeting dangerous inflammation inside artery plaque
A research team showed that a nanotherapeutic medicine can halt the growth of artery plaque cells resulting in the fast reduction of the inflammation that may cause a heart attack.
NIH/National Heart, Lung, and Blood Institute, NIH/Program of Excellence in Nanotechnology Award, National Institutes of Health,Harold S. Geneen Charitable Trust Award, and others

Contact: Lauren Woods
lauren.woods@mountsinai.org
646-634-0869
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 3-Apr-2015
American Journal of Human Genetics
New genetic clues emerge on origin of Hirschsprung's disease
Genetic studies in humans, zebrafish and mice have revealed how two different types of genetic variations team up to cause a rare condition called Hirschsprung's disease. The findings add to an increasingly clear picture of how flaws in early nerve development lead to poor colon function, which must often be surgically corrected. The study also provides a window into normal nerve development and the genes that direct it.
NIH/National Institute of Child Health and Human Development, NIH/National Institute for General Medical Sciences, National Natural Science Foundation of China, Beijing Natural Science Foundation, Beijing Excellent Scientist Fund, and others

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Public Release: 3-Apr-2015
Case Western Reserve to lead international research on resistance to bacteria causing TB
After discovering a unique group of people resistant to tuberculosis (TB) infection, Case Western Reserve researchers are leading an international team dedicated to understanding exactly how they fight off a disease that claims 1.5 million lives each year. The team's goal is to use lessons learned from these resistant individuals to develop an approach to treating and curing TB that is unlike any existing medication.
National Institutes of Health, Bill & Melinda Gates Foundation

Contact: Jeannette Spalding
jeannette.spalding@case.edu
216-368-3004
Case Western Reserve University

Public Release: 3-Apr-2015
Science Advances
CRISPR-Cas editing of C. albicans holds promise for overcoming deadly fungal infections
Candida albicans is a human pathogen that causes potentially lethal infections in immunocompromised individuals. Efforts to overcome Candida's innate resistance to many drugs have been thwarted by an absence of tools enabling genetic modifications. Now, using a modified CRISPR-Cas system, Whitehead Institute researchers can edit the fungus's genome systematically -- an approach that could help scientists understand Candida's unique biology and identify potential drug targets.
National Institutes of Health

Contact: Nicole Giese Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

Public Release: 3-Apr-2015
PLOS Pathogens
Rice can borrow stronger immunity from other plant species, study shows
Rice, one of the world's main staple foods, can boost its built-in immunity against invading disease-causing microbes when immune receptor genes are transferred via genetic engineering from a totally different plant group, this new study shows.
European Molecular Biology Organization, Human Frontier Science Program Organization of France, Gatsby Charitable Foundation in London, US Department of Energy, and National Institutes of Health

Contact: Patricia Bailey
pjbailey@ucdavis.edu
530-756-7127
University of California - Davis

Public Release: 2-Apr-2015
Journal of the National Cancer Institute
Mayo Clinic researchers combine common genetic variants to improve breast cancer
Recent large-scale genomic analyses have uncovered dozens of common genetic variants that are associated with breast cancer. Each variant, however, contributes only a tiny amount to a person's overall risk of developing the disease.
NIH/National Cancer Institute, Breast Cancer Research Foundation

Contact: Joe Dangor
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

Public Release: 2-Apr-2015
Genes & Development
Cancer genes turned off in deadly brain cancer
Scientists have identified a small RNA molecule that can suppress cancer-causing genes in mice with glioblastoma mulitforme, a deadly and incurable type of brain tumor. While standard chemotherapy drugs damage DNA to stop cancer cells from reproducing, the new method stops the source that creates those cancer cells. The approach could also potentially be used for gene silencing in other cancers and diseases of genetic origin.
National Institutes of Health

Contact: Marla Paul
marla-paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 2-Apr-2015
Could a tiny particle stem the plague of citrus greening?
A $4.6 million USDA grant will fund field trials of Zinkicide, a nanoparticle designed to be small enough to move within a citrus trees' stems, leaves, trunk and roots. If successful, it could halt the spread of citrus greening that's devastated citrus industry in Florida and is spreading in other citrus-producing states including California and Texas, as well as other nations.
US Department of Agriculture, NIH/National Institute of Food and Agriculture

Contact: Mark Schlueb
mark.schlueb@ucf.edu
407-823-0221
University of Central Florida

Public Release: 2-Apr-2015
Molecular Cell
USC Norris study finds herpesvirus activates RIG-I receptor to evade body's immune system
Using herpesvirus, molecular immunologists from the University of Southern California Norris Comprehensive Cancer Center have discovered a cellular process that activates a critical immune defense against pathogens, which could have implications for developing drugs to bolster one's immunity to infection. Some herpesvirus infections lead to cancer.
National Institutes of Health, American Cancer Society, USC Norris Comprehensive Cancer Center

Contact: Alison Trinidad
alison.trinidad@usc.edu
323-442-3941
University of Southern California - Health Sciences

Public Release: 2-Apr-2015
AIDS and Behavior
NYU researchers dramatically improve ART adherence for minority PHLA
The intervention was found to be feasible and acceptable. Eight months post-baseline, intervention participants tended to be more likely to evidence 'good' adherence and also had lower HIV viral load levels. Thus the intervention components were highly promising, and merit further study with this vulnerable population.
NIH/National Institutes of Mental Health, Center for Drug Use and HIV Research

Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University

Public Release: 2-Apr-2015
Journal of Exposure Science and Environmental Epidemiology
Placenta reflects arsenic exposure in pregnant women and fetuses, Dartmouth study shows
The placenta can be used to reliably measure arsenic exposure in pregnant women and how much of the toxic metal is transferred to their fetuses, a Dartmouth College study shows in the largest ever analysis of household drinking water arsenic and the mother-to-fetus connection.
NIH/National Institute of Environmental Health, Environmental Protection Agency

Contact: John Cramer
john.cramer@dartmouth.edu
603-646-9130
Dartmouth College

Public Release: 2-Apr-2015
American Naturalist
Being born in lean times is bad news for baboons
The saying 'what doesn't kill you makes you stronger' may not hold up to scientific scrutiny. Baboons born in times of famine are more vulnerable to food shortages later in life, finds a new study. The findings are important because they help explain why people who are malnourished in early childhood often experience poor health as adults.
National Science Foundation, NIH/National Institute on Aging, Duke University, Princeton University, Max Planck Institute for Demographic Research

Contact: Robin Ann Smith
ras10@duke.edu
919-681-8057
Duke University

Public Release: 2-Apr-2015
Proceedings of the National Academy of Sciences
Deconstructing brain systems involved in memory and spatial skills
In work that reconciles two competing views of brain structures involved in memory and spatial perception, researchers at University of California, San Diego School of Medicine have conducted experiments that suggest the hippocampus -- a small region in the brain's limbic system -- is dedicated largely to memory formation and not to spatial skills, such as navigation. The study is published in this week's issue of the Proceedings of the National Academy of Sciences.
US Department of Veterans Affairs, National Science Foundation, NIH/National Institute of Mental Health

Contact: Christina Johnson
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 2-Apr-2015
Journal of Biological Chemistry
Small RNA plays big role suppressing cancer
Researchers at UC Davis have unraveled some of these relationships, identifying several interactions that directly impact liver and colon cancer.
National Institutes of Health

Contact: Dorsey Griffith
dgriffith@ucdavis.edu
916-734-9118
University of California - Davis Health System

Showing releases 151-175 out of 3646.

<< < 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 > >>

     
   

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