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Showing releases 176-200 out of 3164.

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Public Release: 12-Nov-2012
Proceedings of the National Academy of Sciences
On the hunt for rare cancer cells
Jellyfish-inspired device that rapidly and efficiently captures cancer cells from blood samples could enable better patient monitoring.
National Institutes of Health

Contact: Kimberly Allen
allenkc@mit.edu
617-253-2702
Massachusetts Institute of Technology

Public Release: 12-Nov-2012
Journal of Clinical Investigation
HIV-1 vaccine development: Pinning down a moving target
In a study published in the Journal of Clinical Investigation, researchers led by Brad Jones at the University of Toronto in investigated the feasibility of eliminating HIV-infected cells by targeting cellular immune responses against a human endogenous retrovirus.
Pfizer, National Institutes of Health

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 12-Nov-2012
Journal of Clinical Investigation
Home field advantage: Intravaginal immunization may help protect against infection
In a study published in the Journal of Clinical Investigation, researchers led by John Schiller at the National Cancer Institute investigated the immune response to intravaginal immunization in mice infected with a form of the HPV virus carrying a model antigen.
National Institutes of Health

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 12-Nov-2012
Cancer Cell
Study shows how chronic inflammation can cause cancer
A new study has found that interleukin-15 (IL-15) alone can cause large granular lymphocytic (LGL) leukemia, a rare and usually fatal form of cancer. The researchers developed a treatment for the leukemia that showed no discernible side effects in an animal model. The study shows that IL-15 is also overexpressed in patients with LGL leukemia and that it causes similar cellular changes, suggesting that the treatment should also benefit people with the malignancy.
NIH/National Cancer Institute, National Science Foundation

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Medical Center

Public Release: 11-Nov-2012
Nature Neuroscience
New form of brain plasticity: Study shows how social isolation disrupts myelin production
Animals that are socially isolated for prolonged periods make less myelin in the region of the brain responsible for complex emotional and cognitive behavior, researchers at the University at Buffalo and Mt. Sinai School of Medicine report in Nature Neuroscience online.
National Institutes of Health

Contact: Ellen Goldbaum
goldbaum@buffalo.edu
716-645-4605
University at Buffalo

Public Release: 11-Nov-2012
Nature Neuroscience
Schizophrenia genetic networks identified; Connection to autism found
Although schizophrenia is highly genetic in origin, the genes involved in the disorder have been difficult to identify. In the past few years, researchers have implicated several genes, but it is unclear how they act to produce the disorder. A new study by researchers at Columbia University Medical Center identifies affected gene networks and provides insight into the molecular causes of the disease. The paper was published today in the online edition of the journal Nature Neuroscience.
SFARI,MAGNet, NIH/National Institute of Mental Health, Columbia University/Lieber Center, NIH/National Institute of General Medical Sciences, NARSDAD

Contact: Karin Eskenazi
ket2116@columbia.edu
212-342-0508
Columbia University Medical Center

Public Release: 11-Nov-2012
Nature Genetics
Mutations in genes that modify DNA packaging result in Facioscapulohumeral Muscular Dystrophy
A worldwide group of collaborators have found that the way DNA is packaged in people with this form of muscular dystrophy may be responsible for their disease. A genetic error allows the DNA wrapping to relax and thereby allow a muscle-toxic substance to be produced. The mutation occurs in a gene know for its silencing effects.
National Institutes of Health, Muscular Dystrophy Foundation, Norton & Ecklund Family Foundation, FacioScapuloHumeral Muscular Dystrophy Society

Contact: Leila Gray
leilag@uw.edu
206-685-0381
University of Washington

Public Release: 11-Nov-2012
Nature
Game changer for arthritis and anti-fibrosis drugs
In a discovery that can fundamentally change how drugs for arthritis, and potentially many other diseases, are made, University of Utah medical researchers have identified a way to treat inflammation without exposing patients to a serious side effect of current medications: the increased risk for infection.
National Institutes of Health

Contact: Phil Sahm
phil.sahm@hsc.utah.edu
801-581-2517
University of Utah Health Sciences

Public Release: 11-Nov-2012
Nature Genetics
Researchers discover 2 genetic flaws behind common form of inherited muscular dystrophy
An international research team co-led by a scientist at Fred Hutchinson Cancer Research Center has identified two genetic factors behind the third most common form of muscular dystrophy. The findings, published online in Nature Genetics, represent the latest in the team's series of groundbreaking discoveries begun in 2010 regarding the genetic causes of facioscapulohumeral muscular dystrophy, or FSHD.
National Institutes of Health, Friends of FSH Research, Muscular Dystrophy Association, and more

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center

Public Release: 11-Nov-2012
Nature Materials
A better brain implant: Slim electrode cozies up to single neurons
A thin, flexible electrode developed at the University of Michigan is 10 times smaller than the nearest competition and could make long-term measurements of neural activity practical at last.
National Institutes of Health, Center for Neural Communication Technology

Contact: Nicole Casal Moore
ncmoore@umich.edu
734-647-7087
University of Michigan

Public Release: 11-Nov-2012
Nature Medicine
Detection, analysis of 'cell dust' may allow diagnosis, monitoring of brain cancer
A novel miniature diagnostic platform using nuclear magnetic resonance technology is capable of detecting minuscule cell particles known as microvesicles in a drop of blood. Microvesicles shed by cancer cells are even more numerous than those released by normal cells, so detecting them could prove a simple means for diagnosing cancer.
National Institutes of Health

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital

Public Release: 11-Nov-2012
Nature Medicine
It's not just what you eat, but when you eat it
Fat cells store excess energy and signal these levels to the brain. In a new study this week in Nature Medicine researches show that deletion of the clock gene Arntl, also known as Bmal1, in fat cells, causes mice to become obese, with a shift in the timing of when this nocturnal species normally eats. These findings shed light on the complex causes of obesity in humans.
NIH/National Heart Lung and Blood Institute, Medical Research Council

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 11-Nov-2012
Nature Neuroscience
Early stress may sensitize girls' brains for later anxiety
High levels of family stress in infancy are linked to differences in everyday brain function and anxiety in teenage girls, according to new results of a long-running population study by University of Wisconsin-Madison scientists.
National Institutes of Health

Contact: Susan Lampert Smith
ssmith5@uwhealth.org
608-262-7335
University of Wisconsin-Madison

Public Release: 10-Nov-2012
American College of Rheumatology
Expensive arthritis treatment no better than steroid therapy
A randomized, double-blind clinical trial by researchers at Hospital for Special Surgery has revealed that corticosteroids are more effective than the more expensive treatment, hylan G-F 20, in providing pain relief to patients with thumb arthritis.
Arthritis Foundation, the National Institutes of Health

Contact: Phyllis Fisher
phyllis.fisher@gmail.com
212-606-1724
Hospital for Special Surgery

Public Release: 9-Nov-2012
Proceedings of the National Academy of Sciences
A comparative medicine study by Penn vet identifies a new approach to combat viral infections
When a virus such as influenza invades our bodies, interferon proteins are among the first immune molecules produced to fight off the attack. A study by scientists from the University of Pennsylvania School of Veterinary Medicine offers a new strategy for enhancing the effects of interferon in fighting off infection.
National Institutes of Health, University of Pennsylvania

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 9-Nov-2012
Cell
Scientists uncover a new pathway that regulates information processing in the brain
Scientists at The Scripps Research Institute have identified a new pathway that appears to play a major role in information processing in the brain. Their research also offers insight into how imbalances in this pathway could contribute to cognitive abnormalities in humans.
National Institutes of Health, Novartis Advanced Discovery Institute, Baxter Foundation, Helen Dorris Postdoctoral Fellowship

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 9-Nov-2012
Journal of Neuroscience
Hunting neuron killers in Alzheimer's and TBI
Levels of the protein appoptosin in the brain skyrocket in Alzheimer's disease and traumatic brain injury. Appoptosin is known for helping the body make heme, the molecule that carries iron in the blood. In a study published Oct. 31 in the Journal of Neuroscience, Huaxi Xu, Ph.D. and his group at Sanford-Burnham Medical Research Institute discovered that excess heme leads to the overproduction of reactive oxygen species and triggers apoptosis, causing neurons to die.
National Institutes of Health

Contact: Heather Buschman
hbuschman@sanfordburnham.org
858-795-5343
Sanford-Burnham Medical Research Institute

Public Release: 9-Nov-2012
Molecular Nutrition and Food Research
Drinking green tea with starchy food may help lower blood sugar spikes
An ingredient in green tea that helps reduce blood sugar spikes in mice may lead to new diet strategies for people, according to Penn State food scientists.
National Institutes of Health

Contact: Matthew Swayne
mls29@psu.edu
814-865-9481
Penn State

Public Release: 9-Nov-2012
Breast Cancer Research and Treatment
High-quality personal relationships improve survival in women with breast cancer
The quality of a woman's social networks--the personal relationships that surround an individual--appears to be just as important as the size of her networks in predicting breast cancer survival, Kaiser Permanente scientists report in the current issue of Breast Cancer Research and Treatment.
NIH/National Cancer Institute, Molecular Profiles and Lifestyle Factors in Breast Cancer Prognosis

Contact: Catherine Hylas Saunders
csaunders@golinharris.com
202-585-2603
Kaiser Permanente

Public Release: 8-Nov-2012
Renewal grant supports genetic research into arthritis of the spine
An international team of scientists searching for genes that determine the susceptibility and severity of arthritis of the spine has been awarded a five-year renewal grant of $4.3 million from the National Institutes of Health.
NIH/National Institute of Arthritis and Musculoskeletal and Skins Diseases

Contact: Robert Cahill
Robert.Cahill@uth.tmc.edu
713-500-3030
University of Texas Health Science Center at Houston

Public Release: 8-Nov-2012
Cell Stem Cell
Extra chromosome 21 removed from Down syndrome cell line
Scientists succeeded in removing the extra copy of chromosome 21 in cell cultures derived from a person with Down syndrome. Persons with this condition have three copies of this chromosome. The method would not lead to a treatment for Down syndrome, but could lead to treatments for some conditions associated with it, such as leukemia. Comparing tissue development from cell cultures from the same individual, with and without the extra chromosome, could provide clues to developmental delays and early aging problems in Down syndrome.
Horizon Discovery, National Institutes of Health

Contact: Leila Gray
leilag@uw.edu
206-685-0381
University of Washington

Public Release: 8-Nov-2012
Journal of the Academy of Nutrition and Dietetics
Diabetes study: 'Mindful eating' equals traditional education in lowering weight and blood sugar
Eating mindfully, or consuming food in response to physical cues of hunger and fullness, is just as effective as adhering to nutrition-based guidelines in reducing weight and blood sugar levels in adults with Type 2 diabetes, a new study suggests.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Carla Miller
CMiller@ehe.osu.edu
614-292-1391
Ohio State University

Public Release: 8-Nov-2012
Journal of Physiology
Antioxidants may ease PAD blood pressure increase
Low antioxidant levels contribute to increased blood pressure during exercise for people with peripheral arterial disease, according to researchers at Penn State Hershey Heart and Vascular Institute.
National Institutes of Health

Contact: Matthew Solovey
msolovey@hmc.psu.edu
717-531-8606
Penn State

Public Release: 8-Nov-2012
Drug and Alcohol Dependence
Study shows young adults with addiction benefit from active 12 step group participation
Young adults undergoing addiction treatment benefit from regular participation in Twelve Step-based self-help groups after discharge, according to a naturalistic study published electronically and in the journal Drug and Alcohol Dependence. The study was conducted collaboratively by the Center for Addiction Medicine at Massachusetts General Hospital and Harvard Medical School and the Butler Center for Research at Hazelden.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Christine Anderson
canderson@hazelden.org
651-213-4231
Hazelden

Public Release: 8-Nov-2012
Journal of Clinical Oncology
Ovarian cancer patients have lower mortality rates when treated at high-volume hospitals
A study by researchers at the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian/Columbia University Medical Center, recently e-published ahead of print by the Journal of Clinical Oncology, suggests that women who have surgery for ovarian cancer at high-volume hospitals have superior outcomes than similar patients at low-volume hospitals.
NIH/National Cancer Institute

Contact: CUMC Communications
cumcnews@columbia.edu
212-305-3900
Columbia University Medical Center

Showing releases 176-200 out of 3164.

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