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Department of Health and Human Services

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Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 176-200 out of 3499.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>

Public Release: 8-Oct-2014
Clinical Psychological Science
Teenage girls are exposed to more stressors that increase depression risk
Adolescence is often a turbulent time, and it is marked by substantially increased rates of depressive symptoms, especially among girls. New research indicates that this gender difference may be the result of girls' greater exposure to stressful interpersonal events, making them more likely to ruminate, and contributing to their risk of depression. The findings are published in Clinical Psychological Science, a journal of the Association for Psychological Science.
NIH/National Institute of Mental Health

Contact: Anna Mikulak
amikulak@psychologicalscience.org
202-293-9300
Association for Psychological Science

Public Release: 8-Oct-2014
PLOS Biology
Gluing chromosomes at the right place
A new study by Raquel Oliveira, from the Instituto Gulbenkian de Ciência, in collaboration with colleagues from the University of California, Santa Cruz, now shows that the dislocation of particular DNA segments perturbs proper chromosome separation. The results of this study, published now in the open access journal PLOS Biology, raise the possibility that chromosome rearrangements involving these regions, often seen in many cancers, can induce additional errors in cell division and thereby compromise genetic stability.
Marie Curie Career Integration Grant, European Union, National Institutes of Health, California Institute for Regenerative Medicine

Contact: Ines Domingues
idomingues@igc.gulbenkian.pt
Instituto Gulbenkian de Ciencia

Public Release: 8-Oct-2014
American Journal of Preventive Medicine
Large chain restaurants appear to be voluntarily reducing calories in their menu items
New research from the Johns Hopkins Bloomberg School of Public Health finds that large chain restaurants, whose core menu offerings are generally high in calories, fat and sodium, introduced newer food and beverage options that, on average, contain 60 fewer calories than their traditional menu selections in 2012 and 2013.
NIH/National Heart, Lung and Blood Institute

Contact: Susan Murrow
smurrow1@jhu.edu
410-955-7624
Johns Hopkins University Bloomberg School of Public Health

Public Release: 8-Oct-2014
Academic Medicine
Online intervention tool for physician trainees may improve care of substance users
Online learning interventions and small group debriefings can improve medical residents' attitudes and communication skills toward patients with substance use disorders, and may result in improved care for these patients, according to a new study from the Perelman School of Medicine at the University of Pennsylvania and Drexel University College of Medicine published online in Academic Medicine.
NIH/National Institute on Drug Abuse

Contact: Anna Duerr
anna.duerr@uphs.upenn.edu
215-349-8369
University of Pennsylvania School of Medicine

Public Release: 8-Oct-2014
Science
Researchers capture images of elusive protein HIV uses to infect cells
HIV is adept at eluding immune system responses because the protein it uses to infect cells is constantly changing. Now a team of researchers including scientists from Yale have stripped the cloak from this master of disguise, providing a high resolution image of this surface spike protein and monitoring how it constantly changes its shape, information that suggests new ways to attack the virus through drugs and vaccines.
National Institutes of Health, The Cancer Research Institute, China Scholarships Council, International AIDS Vaccine Initiative, Bill & Melinda Gates Foundation, United States Agency for International Development

Contact: Jim Shelton
james.shelton@yale.edu
203-432-3881
Yale University

Public Release: 8-Oct-2014
New England Journal of Medicine
Patient's dramatic response and resistance to cancer drug traced to unsuspected mutations
Patients with lethal thyroid cancer experienced response for 18 months on clinical trial of everolimus. Sequencing of the tumor before and after trials yielded information on why tumor responded to and eventually resisted treatment, identifying mutations that may help guide treatment of patients with cancers with similar mutations.
Next Generation Fund at the Broad Institute, Novartis Pharmaceuticals, Starr Cancer Consortium, NIH/National Cancer Institute

Contact: Teresa Herbert
teresa_herbert@dfci.harvard.edu
617-632-5653
Dana-Farber Cancer Institute

Public Release: 8-Oct-2014
Journal of Clinical Investigation
Novel protein in heart muscle linked to cardiac short-circuiting and sudden cardiac deaths
Cardiovascular scientists at NYU Langone Medical Center have identified in mouse models a protein known as Pcp4 as a regulator of the heart's rhythm. Additionally, when the Pcp4 gene is disrupted, it can cause ventricular arrhythmias. Results from this animal study were released online Oct. 8 in the peer-reviewed publication, The Journal of Clinical Investigation.
National Institutes of Health

Contact: Allison Clair
allison.clair@nyumc.org
212-404-3753
NYU Langone Medical Center / New York University School of Medicine

Public Release: 8-Oct-2014
New England Journal of Medicine
New gene therapy for 'bubble boy' disease appears effective, safe, study in NEJM reports
A new form of gene therapy for boys with X-linked severe combined immunodeficiency syndrome, a life-threatening condition also known as 'bubble boy' disease, appears to be effective and safe, a collaborative international research team from Dana-Farber/Boston Children's Cancer and Blood Disorders Center and other institutions report. Early data suggest the therapy may avoid the late-developing leukemia seen in a quarter of SCID-X1 patients in pioneering gene therapy trials in Europe more than a decade ago.
National Institutes of Health, Harvard Catalyst, Boston Children's Hospital, others

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-3110
Dana-Farber Cancer Institute

Public Release: 7-Oct-2014
Five UCSF researchers win NIH high-risk, high-reward grants
UC San Francisco researchers received five awards announced this week by the National Institutes of Health for high-risk, high-reward scientific research projects.
National Institutes of Health

Contact: Jeffrey Norris
jeffrey.norris@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 7-Oct-2014
Mark Andermann, Ph.D., receives NIH New Innovator Award to study cravings and hunger
Beth Israel Deaconess Medical Center neuroendocrinologist Mark Andermann, Ph.D., has been awarded a prestigious Director's New Innovator Award from the National Institute of Diabetes and Digestive and Kidney Disorders and the NIH Common Fund to study how hunger drives cravings.
National Institutes of Health, NIH/National Institute of Diabetes and Digestive and Kidney Disorders

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 7-Oct-2014
Cell Reports
Survival molecule helps cancer cells hide from the immune system
A new study shows that the molecule nuclear factor kappa B helps tumors grow by inhibiting the body's ability to detect cancer cells. The molecule suppresses immune surveillance mechanisms, including the production of cells that inhibit immune responses. The research suggests that cancer immune therapy might be improved if combined with NF-kB inhibitors, and it provides new details about interactions between cancer cells and non-cancer cells that assist tumor growth.
NIH/National Cancer Institute

Contact: Darrell E. Ward
darrell.ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 7-Oct-2014
Cancer Epidemiology, Biomarkers & Prevention
New at-risk group identified for gastrointestinal stromal tumors
Researchers at the University of California, San Diego School of Medicine have, for the first time, clearly defined the epidemiology of gastrointestinal stromal tumors, which occur primarily in the lining of the stomach and small intestine. One key finding: patients of Asian descent, who have not previously been identified as an at-risk population, are 1.5 times more likely than other patient groups to be diagnosed with this type of tumor.
National Institutes of Health, Gastrointestinal Stromal Tumor Research Fund

Contact: Jackie Carr
jcarr@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 7-Oct-2014
JAMA
H7N9 flu vaccine study shows adjuvant is essential for effective immune response
A clinical trial of an experimental H7N9 avian influenza vaccine found an immune response believed to be protective in 59 percent of study participants who received two injections of inactivated vaccine at the lowest dosage tested when mixed with an adjuvant. Without the adjuvant, there was a minimal immune response.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory Health Sciences

Public Release: 7-Oct-2014
Journal of Substance Abuse Treatment
State policies can influence access to heroin treatment, study finds
Abuse of heroin and prescription opioid drugs is growing rapidly, creating a need for more treatment options. A new study finds that state policies can influence the number of physicians licensed to prescribe buprenorphine, a drug that can treat addiction to heroin and other opioids in outpatient settings.
NIH/National Institute of Drug Abuse

Contact: Warren Robak
robak@rand.org
310-451-6913
RAND Corporation

Public Release: 7-Oct-2014
Cognitive Development
Toddlers regulate behavior to avoid making adults angry
Researchers at the University of Washington have found that children as young as 15 months can detect anger when watching other people's social interactions and then use that emotional information to guide their own behavior.
National Institutes of Health

Contact: Molly McElroy
mollywmc@uw.edu
206-221-1684
University of Washington

Public Release: 7-Oct-2014
PLOS ONE
Study: Stroke-fighting drug offers potential treatment for traumatic brain injury
The only drug currently approved for treatment of stroke's crippling effects shows promise, when administered as a nasal spray, to help heal similar damage in less severe forms of traumatic brain injury. In the first examination of its kind, researchers found in animal studies that the brain's limited ability to repair itself after trauma can be enhanced when treated with the drug tPA, or tissue plasminogen activator.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute on Aging

Contact: Dwight Angell
dwight.angell@hfhs.org
313-876-8709
Henry Ford Health System

Public Release: 7-Oct-2014
Journal of Neuroscience
Working memory hinders learning in schizophrenia
Trouble with working memory makes a distinct contribution to the difficulty people with schizophrenia sometimes have in learning, according to a new study. The researchers employed a specially designed experiment and computational models to distinguish the roles of working memory and reinforcement learning.
NIH/National Institute of Mental Health

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 7-Oct-2014
JAMA
Researchers find link between tobacco use and viral infection that causes oral cancers
Johns Hopkins scientists have shown a strong association between tobacco use or exposure and infection with oral human papillomavirus type 16, the sexually transmitted virus responsible for mouth and throat cancers worldwide. The numbers of such cancers have increased 225 percent in the United States over the past two decades.
NIH/National Institute of Dental and Craniofacial Research, Milton J. Dance Jr. Head and Neck Center at Greater Baltimore Medical Center, Merck

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 7-Oct-2014
Cell Metabolism
Live and let-7: MicroRNA plays surprising role in cell survival
Researchers at the University of California, San Diego School of Medicine have identified a microRNA molecule as a surprisingly crucial player in managing cell survival and growth. The findings, published in the Oct. 7 issue of Cell Metabolism, underscore the emerging recognition that non-coding RNAs -- small molecules that are not translated into working proteins -- help regulate basic cellular processes and may be key to developing new drugs and therapies.
National Institutes of Health, Portuguese Foundation for Science and Technology

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 7-Oct-2014
PLOS Biology
How female flies know when to say 'yes'
A fundamental question in neurobiology is how animals, including humans, make decisions. A new study publishing in PLOS Biology on Oct. 7 reveals how fruit fly females make a very important decision: to either accept or reject male courtship. This decision appears to be generated by a very small number of excitatory neurons that use acetylcholine as their neurotransmitter located in three brain regions. This study provides the framework to understand how decisions are generated.
National Institutes of Health, National Science Foundation

Contact: PLOS Biology
biologypress@plos.org
PLOS

Public Release: 7-Oct-2014
JAMA
JAMA findings reveal vaccine approach to fight pandemic bird flu
A Saint Louis University study in JAMA reveals a vaccination strategy researchers can continue to study to protect people from bird flu that has the potential to become epidemic.
NIH/National Insitite of Allergy and Infectious Diseases

Contact: Nancy Solomon
solomonn@slu.edu
314-977-8017
Saint Louis University

Public Release: 7-Oct-2014
Nature Communications
A new pathway discovered regulating autoimmune diseases
Researchers found that NAD+, a natural molecule found in living cells, plants and food protects against autoimmune diseases by altering the immune response and turning 'destructive' cells into 'protective' cells.
National Institutes of Health, Slim Foundation

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-525-6383
Brigham and Women's Hospital

Public Release: 6-Oct-2014
Journal of Allergy & Clinical Immunology
Asthma risk varies with ethnic ancestry among Latinos, UCSF team finds
Native-American ancestry is associated with a lower asthma risk, but African ancestry is associated with a higher risk, according to the largest-ever study of how genetic variation influences asthma risk in Latinos, in whom both African- and Native-American ancestry is common.
National Institutes of Health

Contact: Jeffrey Norris
jeffrey.norris@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 6-Oct-2014
Annals of Internal Medicine
Program to reduce hospital readmissions doesn't have impact
Researchers at UC San Francisco have found that a nurse-led intervention program designed to reduce readmissions among ethnically and linguistically diverse older patients did not improve 30-day hospital readmission rates.
The Gordon and Betty Moore Foundation, Agency for Healthcare Research and Quality, National Institutes of Health

Contact: Scott Maier
scott.maier@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 6-Oct-2014
Case Western Reserve scientist captures prestigious NIH director's New Innovator Award
For the second consecutive year, a Case Western Reserve University School of Medicine researcher has landed one of the year's much-coveted Director's New Innovator Awards from the National Institutes of Health. Principal investigator Rong Xu, Ph.D., assistant professor of medical informatics, will receive $2,377,000 for five years, starting immediately, to initiate computational analysis of thousands of drugs and their effects.
National Institutes of Health

Contact: Jeannette Spalding
jeannette.spalding@case.edu
216-368-3004
Case Western Reserve University

Showing releases 176-200 out of 3499.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>

     
   

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