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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 176-200 out of 3469.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>

Public Release: 7-Aug-2014
Cancer Prevention Research
Gut microbiome analysis improved noninvasive colorectal cancer screening
Analysis of the gut microbiome more successfully distinguished healthy individuals from those with precancerous adenomatous polyps and those with invasive colorectal cancer compared with assessment of clinical risk factors and fecal occult blood testing, according to data published in Cancer Prevention Research, a journal of the American Association for Cancer Research.
National Institutes of Health

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 7-Aug-2014
Cell
Largest cancer genomic study proposes 'disruptive' new system to reclassify tumors
After analyzing more than 3,500 tumors on multiple technology platforms TCGA researchers say cancers are more likely to be similar based on their cell type of origin as opposed to their tissue type of origin. The study suggests at least 10 percent of cancer patients would be classified differently under this protocol. But Buck faculty Christopher Benz thinks this fraction will swell when more samples and additional tumor types are included in the next analysis.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute

Contact: Kris Rebillot
krebillot@buckinstitute.org
415-209-2080
Buck Institute for Age Research

Public Release: 7-Aug-2014
Cell
Cancer study reveals powerful new system for classifying tumors
Cancers are classified primarily on the basis of where in the body the disease originates, as in lung cancer or breast cancer. According to a new study, however, one in 10 cancer patients would be classified differently using a new classification system based on molecular subtypes instead of the current tissue-of-origin system. This reclassification could lead to different therapeutic options for those patients.
National Institutes of Health

Contact: Tim Stephens
stephens@ucsc.edu
831-459-2495
University of California - Santa Cruz

Public Release: 7-Aug-2014
Neuron
Dramatic growth of grafted stem cells in rat spinal cord injuries
Building upon previous research, scientists at the University of California, San Diego School of Medicine and Veteran's Affairs San Diego Healthcare System report that neurons derived from human induced pluripotent stem cells and grafted into rats after a spinal cord injury produced cells with tens of thousands of axons extending virtually the entire length of the animals' central nervous system.
Veterans Administration, National Institutes of Health, Craig H. Neilsen Foundation, California Institute for Regenerative Medicine, Dr. Miriam and Sheldon G. Adelson Medical Research Foundation

Contact: Jackie Carr
jcarr@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 6-Aug-2014
Nature Biotechnology
Single-cell analysis holds promise for stem cell and cancer research
UC San Francisco researchers have identified cells' unique features within the developing human brain, using the latest technologies for analyzing gene activity in individual cells, and have demonstrated that large-scale cell surveys can be done much more efficiently and cheaply than was previously thought possible.
Damon Tunyon Cancer Research Foundation, California Institute for Regenerative Medicine, National Institutes of Health

Contact: Jeffrey Norris
jeffrey.norris@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 6-Aug-2014
Biology Letters
Galápagos hawks hand down lice like family heirlooms
Studying Galápagos hawks and their lice, a University of Arizona-led research team provides some of the first field evidence for co-divergence between parasites and hosts as a major driver of biodiversity. As the birds diversify into distinct populations on each island, their parasites diversify with them. The findings help explain the rapid rate of parasite evolution.
National Science Foudnation, Saint Louis Zoo/Field Research for Conservation, University of Missouri Research Board, John Templeton Foundation, University of Arizona, National Institutes of Health

Contact: Daniel Stolte
stolte@email.arizona.edu
520-626-4402
University of Arizona

Public Release: 6-Aug-2014
Cancer Research
Brain tumors fly under the body's radar like stealth jets, new U-M research suggests
Brain tumors fly under the radar of the body's defense forces by coating their cells with extra amounts of a specific protein, new research shows. Like a stealth fighter jet, the coating means the cells evade detection by the early-warning immune system that should detect and kill them. The stealth approach lets the tumors hide until it's too late for the body to defeat them.
NIH/National Institute of Neurological Disorders & Stroke

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 6-Aug-2014
Nature
A new way to model cancer
New gene-editing technique from researchers at MIT allows scientists to more rapidly study the role of mutations in tumor development.
National Institutes of Health, NIH/National Cancer Institute

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Public Release: 6-Aug-2014
Proceedings of the National Academy of Sciences
Discovery yields master regulator of toxin production in staph infections
St. Jude Children's Research Hospital scientists have discovered an enzyme that regulates production of the toxins that contribute to potentially life-threatening Staphylococcus aureus infections. The study recently appeared in the scientific journal the Proceedings of the National Academy of Sciences. Researchers also showed that the same enzyme allows Staphylococcus aureus to use fatty acids acquired from the infected individual to make the membrane that bacteria need to grow and flourish.
National Institutes of Health, NIH/National Cancer Institute, American Lebanese Syrian Associated Charities

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 6-Aug-2014
Nature
Stowers researchers reveal molecular competition drives adult stem cells to specialize
Adult organisms ranging from fruit flies to humans harbor adult stem cells, some of which renew themselves through cell division while others differentiate into the specialized cells needed to replace worn-out or damaged organs and tissues. Understanding the molecular mechanisms that control the balance between self-renewal and differentiation in adult stem cells is an important foundation for developing therapies to regenerate diseased, injured or aged tissue.
The Stowers Institute for Medical Research, National Natural Science Foundation of China, Ministry of Science and Technology of China, National Institutes of Health

Contact: Kim Bland, Ph.D.
ksb@stowers.org
816-926-4015
Stowers Institute for Medical Research

Public Release: 5-Aug-2014
Cell
Biology made simpler with clear tissues
Thanks to techniques developed at Caltech, scientists can see through tissues, organs, and even an entire body. The techniques offer new insight into the cell-by-cell makeup of organisms -- and the promise of novel diagnostic medical applications.
NIH/National Institute of Neurological Disorders and Stroke, National Institutes of Health, The Beckman Institute of Caltech, Pew Charitable Trust, Sidney Kimmel Foundation

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Public Release: 5-Aug-2014
Nucleic Acids Research
'Treatments waiting to be discovered' inside new database
A University of Colorado Cancer Center study recently published in the top-ranked journal Nucleic Acids Research describes a database named multiMiR, the most comprehensive database collecting information about microRNAs and their targets.
National Institutes of Health, NIH/National Cancer Institute

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 5-Aug-2014
Optics Express
Watching chemistry in motion: Chemical environments mapped using molecular vibrations
Scientists have long known that a molecule's behavior depends on its environment. Taking advantage of this phenomenon, a group of researchers at the University of Chicago developed a new technique to map microscopic environments using the vibrations of molecules.
National Science Foundation, National Institutes of Health, Deutsche Forschungsgemeinschaft

Contact: Steve Koppes
skoppes@uchicago.edu
773-702-8366
University of Chicago

Public Release: 5-Aug-2014
Journal of the American Heart Association
Pistachios may lower vascular response to stress in type 2 diabetes
Among people with type 2 diabetes, eating pistachios may reduce the body's response to the stresses of everyday life, according to Penn State researchers.
American Pistachio Growers, National Institutes of Health

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State

Public Release: 5-Aug-2014
Experimental Biology and Medicine
Pyruvate oxidation is critical determinant of pancreatic islet number and β-cell mass
Glucose is not only a major nutrient regulator of insulin secretion but also impacts on gene expression in β-cells. Using a mouse model of β-cell-specific knock-out of Pdha1 gene which encodes the α subunit of the pyruvate dehydrogenase component of the pyruvate dehydrogenase complex, the authors demonstrated that mitochondrial metabolism of pyruvate derived from glucose not only regulates insulin secretion but also directly influences β-cell growth and plasticity.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Canadian Institute of Health Research

Contact: M.S. Patel
mspatel@buffalo.edu
Society for Experimental Biology and Medicine

Public Release: 5-Aug-2014
Journal of Family Psychology
Marital tension between mom and dad can harm each parent's bond with child, study finds
Children suffer when mom and dad have problems in their marriage, according to a new study. Dads, especially, let negative emotions and tension from their marriage spill over and harm the bond with their child, says psychologist and lead-author Chrystyna Kouros, Southern Methodist University, Dallas. Conversely, moms in poor quality marriages sometimes compartmentalized marital tension and improved the relationship with their child. The findings indicate marriage quality closely affects the parent-child bond, Kouros said.
NIH/National Institute of Child Health and Human Development

Contact: Margaret Allen
mallen@smu.edu
214-768-7664
Southern Methodist University

Public Release: 5-Aug-2014
American Journal of Respiratory and Critical Care Medicine
Cancer fighter can help battle pneumonia
The tip of an immune molecule known for its skill at fighting cancer may also help patients survive pneumonia, scientists report.
National Institutes of Health

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Public Release: 5-Aug-2014
Journal of General Internal Medicine
Rituals can help older people remember to take their asthma meds
Storing asthma medication in the bathroom and making it part of a daily routine may be helpful advice that doctors can give their older asthmatic patients who struggle to remember to take their daily prescribed medication. This advice comes from Alex Federman, senior author of a study which discusses how elderly asthmatics cope with taking their inhaled corticosteroid medication as prescribed. The findings appear in the Journal of General Internal Medicine, published by Springer.
NIH/National Heart, Lung and Blood Institute

Contact: Joan Robinson
joan.robinson@springer.com
49-622-148-78130
Springer

Public Release: 5-Aug-2014
PLOS Biology
In search for Alzheimer's drug, a major STEP forward
Researchers at Yale School of Medicine have discovered a new drug compound that reverses the brain deficits of Alzheimer's disease in an animal model. Their findings are published in the Aug. 5 issue of the journal PLOS Biology.
National Institutes of Health, American Health Assistance Foundation, Alzheimer's Drug Discovery Foundation

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University

Public Release: 5-Aug-2014
Genome Research
Seamless gene correction of beta-thalassemia mutations in patient-specific cells
A major hurdle in gene therapy is the efficient integration of a corrected gene into a patient's genome without mutating off-target sites. In a paper published today in Genome Research, scientists have used CRISPR/Cas genome editing technology to seamlessly and efficiently correct disease-causing mutations in cells from patients with beta-thalassemia.
National Institutes of Health

Contact: Peggy Calicchia
calicchi@cshl.edu
516-422-4012
Cold Spring Harbor Laboratory

Public Release: 5-Aug-2014
PLOS Medicine
Monthly preventative treatment with a new drug combination reduces malaria in children
Preventative treatment with a monthly dose of a newer antimalarial drug can reduce the risk of malarial infection among young children, according to a study published in this week's PLOS Medicine. The study, conducted by Victor Bigira and colleagues at San Francisco General Hospital and the Makerere University College of Health Sciences in Kampala, Uganda, finds that treating young children with dihydroartemisinin-piperaquine decreased their risk of contracting malaria.
National Institutes of Health

Contact: Maya Sandler
medicinepress@plos.org
PLOS

Public Release: 4-Aug-2014
Developmental Cell
An embryonic cell's fate is sealed by the speed of a signal
Early in development, chemical signals tell cells whether to turn into muscle, bone, brain or other tissue. By tracking cells' responses to signals, researchers found the speed at which the signal arrives has an unexpected influence on that decision.
National Institutes of Health, National Science Foundation, European Molecular Biology Organization, Human Frontier Science Program

Contact: Zach Veilleux
zveilleux@rockefeller.edu
212-327-8982
Rockefeller University

Public Release: 4-Aug-2014
JAMA
Version 2.0 of Prostate Cancer Risk Calculator now online, complete with emojis
A calculator to help men and their doctors assess their risk of prostate cancer has had a major upgrade, described online Monday in the Journal of the American Medical Association. 'The current version gives a more nuanced result that helps understand a man's risk of prostate cancer,' said Ian M. Thompson Jr., M.D., director of the Cancer Therapy & Research Center at the UT Health Science Center, who helped develop the risk calculator.
NIH/National Cancer Institute

Contact: Elizabeth Allen
210-450-2020
University of Texas Health Science Center at San Antonio

Public Release: 4-Aug-2014
GW researcher receives grant to study environmental factors that contribute to autism
Valerie Hu, Ph.D., professor of biochemistry and molecular medicine at the George Washington University, was awarded $435,000 from the National Institute of Environmental Health Sciences to study how certain environmental factors affect the gene RORA, which has been shown to be an important regulator of multiple genes of neurological significance in those with autism.
NIH/National Institute of Environmental Health Sciences

Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University

Public Release: 4-Aug-2014
American Journal of Preventive Medicine
Eating baked or broiled fish weekly boosts brain health, Pitt study says
Eating baked or broiled fish once a week is good for the brain, regardless of how much omega-3 fatty acid it contains, according to researchers at the University of Pittsburgh School of Medicine. The findings, published online recently in the American Journal of Preventive Medicine, add to growing evidence that lifestyle factors contribute to brain health later in life.
NIH/ National Heart, Lung, and Blood Institute, NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute on Aging

Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences

Showing releases 176-200 out of 3469.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>

     
   

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