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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 176-200 out of 3816.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>

Public Release: 14-Jul-2015
Radiology
Substance abuse reduces brain volume in women but not men
Stimulant drug abuse has long-term effects on brain volume in women, according to a new study. Brain structures involved in reward, learning and executive control showed vast changes even after a prolonged period of abstinence from drug use.
National Institutes of Health

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

Public Release: 14-Jul-2015
Radiology
Substance abuse is associated with lower brain volume in women but not in men
A new study by a team of researchers at the University of Colorado School of Medicine on the Anschutz Medical Campus found that long-term stimulant abuse had more significant effects on brain volume in women compared with men. 'While the women previously dependent on stimulants demonstrated widespread brain differences when compared to their healthy control counterparts, the men demonstrated no significant brain differences,' said Jody Tanabe, M.D., professor of radiology.
NIH/National Institute on Drug Abuse

Contact: Mark Couch
mark.couch@ucdenver.edu
303-724-5377
University of Colorado Denver

Public Release: 13-Jul-2015
ACS Biomaterials Science & Engineering
Chemotherapeutic coatings enhance tumor-frying nanoparticles
In a move akin to adding chemical weapons to a firebomb, researchers at Duke University have devised a method to deposit a thin layer of hydrogels on the surface of nanoshells designed to absorb infrared light and generate heat to destroy tumors. When heated by the nanoshells, these special hydrogels lose their water content and any drugs trapped within, creating a formidable one-two punch.
National Institutes of Health

Contact: Ken Kingery
ken.kingery@duke.edu
919-660-8414
Duke University

Public Release: 13-Jul-2015
Journal of Pediatrics
Baby's first stool can alert doctors to future cognitive issues, new CWRU study finds
A newborn's first stool can signal the child may struggle with persistent cognitive problems, according to Case Western Reserve University Project Newborn researchers. In particular, high levels of fatty acid ethyl esters found in the meconium (a newborn's first stool) from a mother's alcohol use during pregnancy can alert doctors that a child is at risk for problems with intelligence and reasoning.
NIH/National Institute on Drug Abuse

Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University

Public Release: 13-Jul-2015
Nature Neuroscience
Learning impacts how the brain processes what we see
From the smell of flowers to the taste of wine, our perception is strongly influenced by prior knowledge and expectations, a cognitive process known as top-down control. In a University of California, San Diego School of Medicine study, a research team led by Takaki Komiyama, PhD, assistant professor of neurosciences and neurobiology, reports that in mouse models, the brain significantly changed its visual cortex operation modes by implementing top-down processes during learning.
National Institutes of Health, Japan Science and Technology Agency, Pew Charitable Trusts, Alfred P. Sloan Foundation, David & Lucile Packard Foundation, Human Frontier Science Program, McKnight Foundation and New York Stem Cell Foundation

Contact: Yadira Galindo
ygalindo@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 13-Jul-2015
Alzheimer's & Dementia
Impact of major Alzheimer's-related gene may be felt years before any symptoms appear
The best-known genetic variant linked to Alzheimer's disease may be 'at work' promoting deposits of plaque in the brain long before any symptoms of the disease can be measured on tests.
NIH/National Institute on Aging, Alzheimer's Disease Neuroimaging Initiative, Alzheimer's Association

Contact: Eric Schoch
eschoch@iu.edu
317-274-8205
Indiana University

Public Release: 13-Jul-2015
Journal of Neuroscience
Found: A likely new contributor to age-related hearing loss
Conventional wisdom has long blamed age-related hearing loss almost entirely on the death of sensory hair cells in the inner ear, but research from neuroscientists at Johns Hopkins has provided new information about the workings of nerve cells that suggests otherwise.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Public Release: 13-Jul-2015
Proceedings of the National Academy of Sciences
Nutrients turn on key tumor signaling molecule, fueling resistance to cancer therapy, Ludwig Cancer Research study shows
Tumors can leverage glucose and another nutrient, acetate, to resist targeted therapies directed at specific cellular molecules, according to Ludwig Cancer Research scientists studying glioblastoma, a deadly brain cancer. The findings, published in the July 13 Proceedings of the National Academy of Sciences, demonstrate that nutrients can strongly affect the signaling molecules that drive tumors.
Ludwig Cancer Research, NIH/National Institute for Neurological Diseases and Stroke, Defeat GBM Research Collaborative, NIH/National Cancer Institute, Ben and Catherine Ivy Foundation, Ziering Family Foundation, Ichiro Kanehara Foundation, and others

Contact: Rachel Steinhardt
rsteinhardt@licr.org
212-450-1582
Ludwig Institute for Cancer Research

Public Release: 13-Jul-2015
Nature Methods
Troubleshooting the gene targeting process
Researchers have developed a new, straightforward software program for predicting the best RNAs to direct Cas9 to gene targets, eliminating trial-and-error process.
National Institutes of Health

Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School

Public Release: 13-Jul-2015
Proceedings of the National Academy of Sciences
Fat fish illuminate human obesity
Blind cavefish that have adapted to annual cycles of starvation and binge-eating have mutations in the gene MC4R, the same gene that is mutated in certain obese people with insatiable appetites, according to a new study led by Harvard Medical School geneticists.
National Institutes of Health

Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School

Public Release: 13-Jul-2015
Proceedings of the National Academy of Sciences
Lung simulation could improve respiratory treatment
The first computer model that predicts the flow of liquid medication in human lungs is providing new insight into the treatment of acute respiratory distress syndrome.
National Institutes of Health

Contact: Gabe Cherry
gcherry@umich.edu
734-763-2937
University of Michigan

Public Release: 13-Jul-2015
JAMA Internal Medicine
Study of IRB members' industry relationships finds improvement, but some issues persist
A follow-up to a 2005 study of industry relationships among members of Institutional Review Boards at academic health centers finds both improvements in the management of such relationships, with increased levels of disclosure and fewer problematic relationships, and the persistence of problems such as IRB members' voting on protocols with which they may have conflicts of interest, a violation of federal regulations.
NIH/National Institute of General Medical Studies

Contact: Noah Brown
nbrown9@partners.org
617-643-3907
Massachusetts General Hospital

Public Release: 13-Jul-2015
Annals of Internal Medicine
Elective surgery is associated with lower risk of death than drugs for ulcerative colitis
Patients over 50 with ulcerative colitis, a chronic disease of the colon, who undergo surgery to treat their condition live longer than those who are treated with medications, according to a new study from the Perelman School of Medicine at the University of Pennsylvania. The results are published this week in Annals of Internal Medicine.
National Institutes of Health, Agency for Healthcare Research and Quality

Contact: Katie Delach
katie.delach@uphs.upenn.edu
215-349-5964
University of Pennsylvania School of Medicine

Public Release: 13-Jul-2015
Nature Genetics
Skin cancer marker plays critical role in tumor growth
New research from the Johns Hopkins Bloomberg School of Public Health suggests that the protein keratin 17 -- the presence of which is used in the lab to detect and stage various types of cancers -- is not just a biomarker for the disease, but may play a critical role in tumor growth.
NIH/National Cancer Institute, NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH/National Institute of General Medical Sciences

Contact: Stephanie Desmon
sdesmon1@jhu.edu
410-955-7619
Johns Hopkins University Bloomberg School of Public Health

Public Release: 13-Jul-2015
Cancer Cell
New approach to treating B-cell acute lymphoblastic leukemia shows promise
A new compound that locks a disease-related protein into an inactive position stifled the growth of an aggressive form of leukemia in laboratory and animal tests, researchers at Dana-Farber Cancer Institute and other institutions report.
Dana-Farber/Novartis Drug Discovery Program, NIH/National Cancer Institute, NIH/National Heart, Lung, and Blood Institute

Contact: Teresa M Herbert
teresa_herbert@dfci.harvard.edu
617-632-4090
Dana-Farber Cancer Institute

Public Release: 13-Jul-2015
Journal of Clinical Investigation
Researchers develop aerosolized vaccine that protects primates against Ebola
A collaborative team from the University of Texas Medical Branch at Galveston and the National Institutes of Health have developed an inhalable vaccine that protects primates against Ebola.
National Institutes of Health

Contact: Donna Ramirez
donna.ramirez@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston

Public Release: 13-Jul-2015
Journal of Clinical Investigation
Stem cells provide lasting pain relief in mice
Duke researchers have identified a promising stem cell based-therapy to address the chronic pain that affects more than one-third of the US adult population. In mice, bone marrow stromal cells were found to provide lasting relief for chronic pain caused by nerve damage. The findings also may advance cell-based therapies in chronic pain conditions, lower back pain and spinal cord injuries.
National Institutes of Health

Contact: Robin A. Smith
ras10@duke.edu
919-681-8057
Duke University

Public Release: 12-Jul-2015
Group Health and UW get $13 million to study aging and the brain
The National Institute on Aging awarded the Group Health-University of Washington Adult Changes in Thought study a grant of nearly $13 million to continue its work for the next five years through April 2020. One of the longest-running studies of its kind, the ACT study has been thoroughly tracking what happens with a cohort of randomly selected Group Health patients older than 65 as they lead their lives.
NIH/National Institute on Aging

Contact: Rebecca Hughes
hughes.r@ghc.org
206-287-2055
Group Health Research Institute

Public Release: 10-Jul-2015
Could hormone-related cancers start before birth?
Much attention has been paid to genetics in breast cancer as disease rates rise, but most women have no family history, suggesting that there is an environmental risk we don't yet understand, says environmental health scientist Laura Vandenberg in the School of Public Health and Health Sciences at UMass Amherst. She is launching a three-year, $450,000 research program supported by NIEHS to investigate the possibility that exposure to estrogen or estrogen-like chemicals in the womb may be a factor.
NIH/National Institute of Environmental Health Sciences

Contact: Janet Lathrop
jlathrop@admin.umass.edu
413-545-0444
University of Massachusetts at Amherst

Public Release: 10-Jul-2015
Science Translational Medicine
Improved sperm diagnostic test may pinpoint best fertility treatment for couples
A Wayne State University School of Medicine professor, in collaboration with researchers at CReAte Fertility Center, University of Toronto, Harvard University and Georgia Reagents University, has developed the first diagnostic test for sperm RNA based on next-generation sequencing. For couples with unexplained infertility, the test may help determine the best infertility treatment for couples having difficulty conceiving.
National Institutes of Health

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research

Public Release: 10-Jul-2015
Science
New understanding of genetic susceptibility to infections by Candida and Mycobacterium
By an international collaboration study with the Rockefeller University, researchers at Hiroshima University identified bi-allelic mutations in RORC, which encoded RORγ and RORγT, in seven patients from three kindreds with an unusual combination of candidiasis and mycobacteriosis. They discovered that human RORC is essential not only for the development of IL-17-producing T cells against Candida but also for the activation of IFN-γ-producing T cells and for systemic protection against Mycobacterium.
NIH/National Center for Research Resources, NIH/National Center for Advancing Sciences, National Institutes of Health, and others

Contact: Norifumi Miyokawa
pr-research@office.hiroshima-u.ac.jp
Hiroshima University

Public Release: 9-Jul-2015
Current Biology
A new wrinkle: Geometry of brain's outer surface correlates with genetic heritage
Researchers at the University of California, San Diego and the School of Medicine have found that the three-dimensional shape of the cerebral cortex -- the wrinkled outer layer of the brain controlling many functions of thinking and sensation -- strongly correlates with ancestral background. The study opens the door to more precise studies of brain anatomy going forward and could eventually lead to more personalized medicine approaches for diagnosing and treating brain diseases.
PING, NIH/National Institute on Drug Abuse, NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: Bonnie Ward
bjward@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 9-Jul-2015
Cell
Bacteria use DNA replication to time key decision
Bacteria use their DNA replication cycle to time critical, once-in-a-lifetime decisions about whether to reproduce or form spores. The new finding by researchers from Rice University, the University of California at San Diego and the University of Houston appears this week in the journal Cell.
National Science Foundation, National Institutes of Health, Howard Hughes Medical Institute

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Public Release: 9-Jul-2015
Nature Communications
Study advances potential of tumor genome sequencing and DNA-based blood tests in precision treatment
In a genome-sequencing study of pancreatic cancers and blood in 101 patients, Johns Hopkins Kimmel Cancer Center scientists say they found at least one-third of the patients' tumors have genetic mutations that may someday help guide precision therapy of their disease. Results of blood tests to detect DNA shed from tumors, they say, also predicted cancer recurrence more than half a year earlier than standard imaging methods.
American Association for Cancer Research Stand Up To Cancer-Dream Team, NIH/National Cancer Institute FasterCures, European Community's Seventh Framework Programme, Swim Across America, Dennis Troper and Susan Wojcicki

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 9-Jul-2015
Doctors to get better access to digital data
With $1.3 million and a top-priority ranking from the National Institutes of Health, UA College of Engineering researchers are developing data compression software to make biomedical big data universally available.
National Institutes of Health

Contact: Daniel Stolte
stolte@email.arizona.edu
520-626-4402
University of Arizona

Showing releases 176-200 out of 3816.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>

     
   

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