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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 176-200 out of 3685.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>

Public Release: 9-Nov-2015
Cancer Cell
New study describes how glucose regulation enables malignant tumor growth
A new study led by researchers at The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute identifies a key pathway used by cancer cells to make the lipids by integrating oncogenic signaling, fuel availability and lipid synthesis to support cell division and rapid tumor growth.
National Institutes of Health, American Cancer Society Research Scholar Grant

Contact: Amanda J Harper
Ohio State University Wexner Medical Center

Public Release: 9-Nov-2015
Proceedings of the National Academy of Sciences
Scientific research is conservative but could be accelerated, analysis finds
Institutional and cultural pressures lead scientists to avoid risk-taking and choose inefficient research strategies, two new University of Chicago papers conclude. Despite increased opportunities for groundbreaking experiments, most scientists choose conservative research strategies to reduce personal risk, which makes collective discovery slower and more expensive. However, these computational studies also uncovered more efficient approaches for maximizing discovery and identified the approaches used more often by scientists who have won Nobel Prizes and other prestigious awards.
National Science Foundation, National Institutes of Health, Defense Advanced Research Projects Agency, Air Force Office of Scientific Research

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 9-Nov-2015
American Heart Association's Scientific Sessions 2015
New England Journal of Medicine
Study shows benefits of intensive blood pressure management
Patients whose blood pressure target was lowered to a systolic goal of less than 120 mmHg had their risk for heart attack, heart failure or stroke reduced by 24 percent, and risk for death lowered by 27 percent, but was accompanied by increased risk for adverse events such as kidney abnormalities. Primary results from the Systolic Blood Pressure Intervention Trial (SPRINT) will be published in the New England Journal of Medicine on Nov. 9.
National Institutes of Health

Contact: Julie Kiefer
University of Utah Health Sciences

Public Release: 9-Nov-2015
Nature Biotechnology
USC and Sangamo researchers advance genome editing of blood stem cells
Genome editing techniques for blood stem cells just got better, thanks to a team of researchers at USC and Sangamo BioSciences. In an upcoming study in Nature Biotechnology, co-first authors Colin M. Exline, Ph.D., from USC and Jianbin Wang, Ph.D., from Sangamo BioSciences describe a new, more efficient way to edit genes in blood-forming or 'hematopoietic' stem and progenitor cells.
California HIV/AIDS Research Program, National Institutes of Health, California Institute for Regenerative Medicine, James B. Pendleton Charitable Trust

Contact: Zen Vuong
University of Southern California

Public Release: 9-Nov-2015
Nature Methods
Flipping the switch to better see cancer cells at depths
Using a high-tech imaging method, a team of biomedical engineers at the School of Engineering & Applied Science at Washington University in St. Louis was able to see individual, early-developing cancer cells deeper in tissue than ever before with the help of a novel protein from a bacterium.
National Institutes of Health, European Union, Neuroscience Blueprint Center Core

Contact: Erika Ebsworth-Goold
Washington University in St. Louis

Public Release: 9-Nov-2015
American Heart Association's Scientific Sessions 2015
Partners of heart defibrillator patients concerned about resuming sex
Partners of people with heart defibrillators have more concerns about resuming sexual activity than patients immediately after the device is implanted. Concerns declined for both over three months.
NIH/National Heart, Lung, and Blood Institute

Contact: Darcy Spitz
American Heart Association

Public Release: 8-Nov-2015
2015 ACR/ARHP Annual Meeting
Complement activation predicts pregnancy complications in women with lupus
Hospital for Special Surgery investigators have identified multiple clinical and biologic markers that correlate with adverse pregnancies in women with lupus, including, most recently, the activation of complement, a series of proteins that protect us from invading microbes.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Tracy Hickenbottom
Hospital for Special Surgery

Public Release: 8-Nov-2015
American Heart Association's Scientific Sessions 2015
Eating more homemade meals may reduce risk of type 2 diabetes
People who mostly eat meals prepared at home may have a slightly lower risk of developing type 2 diabetes. Eating more homemade meals may be associated with less weight gain over time, which could contribute to a lower risk of developing type 2 diabetes.
This study is funded by National Institutes of Health.

Contact: Darcy Spitz
American Heart Association

Public Release: 7-Nov-2015
ACR/ARHP 2015 Annual Meeting
Deaths from heart disease declining among rheumatoid arthritis patients
Rheumatoid arthritis patients are twice as likely as the average person to develop heart disease, but a new study shows that efforts to prevent heart problems and diagnose and treat heart disease early may be paying off.
NIH/National Institute on Aging, NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Sharon Theimer
Mayo Clinic

Public Release: 6-Nov-2015
Researchers uncover diverse subtypes of serotonin-producing neurons
It used to be enough to call a serotonergic neuron a serotonergic neuron. These brain cells make the neurotransmitter serotonin, which helps regulate mood, appetite, breathing rate, body temperature and more. Recently, however, scientists have begun to learn that these neurons differ from one another -- and that the differences likely matter in dysfunction and disease.
National Institutes of Health, American SIDS Institute, Harvard Stem Cell Institute, NARSAD Distinguished Investigator Grant

Contact: David Cameron
Harvard Medical School

Public Release: 6-Nov-2015
Journal of National Cancer Institute
Targeted treatment produces rapid shrinkage of recurrent, BRAF-mutant brain tumor
Massachusetts General Hospital investigators report the first successful use of a targeted therapy to treat a patient with BRAF-mutant craniopharyngioma, a debilitating, recurrent brain tumor.
National Institutes of Health, Brain Science Foundation, Susan G. Komen for the Cure, Terri Brodeur Breast Cancer Foundation, Conquer Cancer Foundation, American Brain Tumor Association

Contact: Katie Marquedant
Massachusetts General Hospital

Public Release: 6-Nov-2015
American Journal of Cardiology
Bang for the buck in stroke prevention: U-M study compares new & old drugs
When it comes to preventing stroke, millions of Americans with irregular heartbeats face a choice: Take one of the powerful but pricey new pills they see advertised on TV, or a much cheaper 60-year-old drug can be a hassle to take, and doesn't prevent stroke as well. It doesn't seem like much of a contest -- until you do the math. Which a new study does.
National Institutes of Health

Contact: Kara Gavin
University of Michigan Health System

Public Release: 6-Nov-2015
Cell Reports
Protein movement of hair bundles in the inner ear may preserve hearing for life
Scientists at Case Western Reserve University School of Medicine have discovered that the movement of protein within hair cells of the inner ear shows signs of a repair and renewal mechanism. The investigator's findings will appear as the cover paper in the Nov. 17 edition of Cell Reports and are now available in the online edition of the journal.
National Institutes of Health, Center for Clinical Research and Technology at University Hospitals Case Medical Center

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 6-Nov-2015
JAMA Neurology
MRI-based screening improves assignment of stroke patients to endovascular treatment
A Massachusetts General Hospital-developed system for determining which patients with severe strokes are most likely to benefit from catheter-based systems for blood clot removal led to a greater percentage of screened patients receiving treatment and to outcomes similar to recent studies that found significant treatment benefits.
National Institutes of Health, Agency for Healthcare Research and Quality, National Center for Research Resources

Contact: Terri Ogan
Massachusetts General Hospital

Public Release: 6-Nov-2015
Moffitt's Physical Sciences -- Oncology Center receives $10.4 million grant
Moffitt Cancer Center was awarded a $10.4 million grant from the National Cancer Institute for its Physical Science -- Oncology Centers.
NIH/National Cancer Institute

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 6-Nov-2015
American Journal of Pathology
Genetic modification shows promise for preventing hereditary hearing loss
A mitochondrial defect is responsible for a type of human hereditary deafness that worsens over time and can lead to profound hearing loss. Using a genetically modified mice model with a mitochondrial dysfunction that results in a similar premature hearing loss, researchers showed that precise genetic reduction of an enzyme, AMP kinase, can rescue the hearing loss. Their results are reported in the American Journal of Pathology.
National Institutes of Health, Yale Claude D. Pepper Older American Independence Center, European Molecular Biology Organization

Contact: Eileen Leahy
Elsevier Health Sciences

Public Release: 6-Nov-2015
Drug protects fertility and may prolong life in chemo-treated mice
A University of Wisconsin-Madison physician and her research team have shown that a heart medication can prevent ovarian damage and improve survival in adolescent mice after chemotherapy. The treatment also increased the number of their healthy offspring.
Wisconsin Alumni Research Foundation, National Institutes of Health, University of Wisconsin Carbone Cancer Center

Contact: Sana Salih
University of Wisconsin-Madison

Public Release: 6-Nov-2015
Nature Communications
New way to find DNA damage
University of Utah chemists devised a new way to detect chemical damage to DNA that sometimes leads to genetic mutations responsible for many diseases, including various cancers and neurological disorders.
National Institutes of Health

Contact: Lee J. Siegel
University of Utah

Public Release: 5-Nov-2015
Chemistry & Biology
Temple researchers: Small molecule inhibitor shows promise in precision cancer targeting
Cancer cells with BRCA1 or BRCA2 gene mutations are key targets for cancer therapeutics. Yet, few agents can selectively eliminate cells deficient in BRCA, and none can do so without the risk of inducing drug resistance. Lewis Katz School of Medicine at Temple University scientists think they can help overcome that problem, thanks to their discovery of a molecule that selectively kills BRCA-deficient cancer cells by blocking the activity of an alternative DNA repair pathway.
DOD/Breast Cancer Breakthrough Award, National Institutes of Health

Contact: Jeremy Walter
Temple University Health System

Public Release: 5-Nov-2015
The astounding genome of the dinoflagellate
Dinoflagellates live free-floating in the ocean or symbiotically with corals, serving up -- or as -- lunch to a host of mollusks, tiny fish and coral species. But when conditions are wrong, dinoflagellates poison shellfish beds with red tides and abandon coral reefs to a slow, bleached death. Globally, this is happening more and more often. Seeking answers, a team of researchers sequenced the complete genome of a dinoflagellate species for the first time.
Natural Science Foundation of China, National Science Foundation, National Institutes of Health, National Science and Engineering Research Council of Canada

Contact: Kim Krieger
University of Connecticut

Public Release: 5-Nov-2015
New England Journal of Medicine
TCGA findings provide molecular background for second most common kidney cancer
Scientists with the Cancer Genome Atlas, a National Institutes of Health-funded project, have molecularly characterized two types of the second most common kidney cancer and classified several subtypes of the disease.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute

Contact: Beth Hinshaw Hall
Van Andel Research Institute

Public Release: 5-Nov-2015
Study explores nicotine patch to treat memory loss
Vanderbilt University Medical Center has received a $9.4 million grant from the National Institute on Aging (NIA) to test the effectiveness of a transdermal nicotine patch in improving memory loss in older adults with mild cognitive impairment, a precursor to Alzheimer's disease.
NIH/National Institute on Aging

Contact: Craig Boerner
Vanderbilt University Medical Center

Public Release: 5-Nov-2015
Study: Strength of brain connectivity varies with fitness level in older adults
A new study shows that age-related differences in brain health -- specifically the strength of connections between different regions of the brain -- vary with fitness level in older adults.
NIH/National Institute on Aging, Abbott Nutrition

Contact: Sarah Banducci
University of Illinois at Urbana-Champaign

Public Release: 5-Nov-2015
Georgia State scientist gets $1.675 million to study link between cancer and DNA replication, repair
Ivaylo Ivanov, associate professor of chemistry at Georgia State University, has received a five-year, $1.675 million federal grant to study how problems with DNA replication and repair may lead to cancer susceptibility and inheritable genetic diseases.
NIH/National Institute of General Medical Sciences

Contact: LaTina Emerson
Georgia State University

Public Release: 5-Nov-2015
Teaching the blind to draw -- and do STEM
$1 million NIH technology transfer grant will speed adoption of interactive raised line graphics devices in schools that help young blind students learn to draw and, later, facilitate their taking math and science courses that require them to interact with graphics. The devices were developed by University of Vermont start-up E.A.S.Y. LLC.
National Institutes of Health

Contact: Jeff Wakefield
University of Vermont

Showing releases 176-200 out of 3685.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>


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