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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 176-200 out of 3488.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>

Public Release: 16-Sep-2014
Journal of the National Cancer Institute
Lactation linked to reduced estrogen receptor-negative, triple-negative breast cancer risk
Women who have had children (parous women) appear to have an increased risk of developing estrogen receptor-negative breast cancer, the subtype that carries a higher mortality rate and is more common in women of African ancestry. A similar relationship was found for triple-negative breast cancer. However, the association between childbearing and increased risk of estrogen receptor-negative and triple-negative breast cancer was largely confined to the women who had never breastfed.
NIH/National Cancer Institute

Contact: Jenny Eriksen Leary
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center

Public Release: 16-Sep-2014
ASTRO's 56th Annual Meeting
Prostate cancer patients who receive hypofractionated RT report consistent QoL
Prostate cancer patients who received hypofractionated radiation therapy reported that their quality of life, as well as bladder and bowel function were at similar levels before and after radiation therapy, according to research presented today at the American Society for Radiation Oncology's 56th Annual Meeting.
National Institutes of Health

Contact: Michelle Kirkwood
press@astro.org
703-286-1600
American Society for Radiation Oncology

Public Release: 16-Sep-2014
PLOS Medicine
Point-of-care CD4 testing is economically feasible for HIV care in resource-limited areas
A study by Massachusetts General Hospital investigators, working in collaboration with colleagues in Mozambique and South Africa, indicates that routine use of point-of-care CD4 testing at the time of HIV diagnosis would be cost effective in countries where health care and other resources are severely limited.
NIH/National Institute of Allergy and Infectious Disease, UK Department for International Development, Clinton Health Access Initiative

Contact: Noah Brown
nbrown9@partners.org
617-643-3907
Massachusetts General Hospital

Public Release: 16-Sep-2014
Nature Communications
Human faces are so variable because we evolved to look unique
Why are human faces so variable compared to other animals, from lizards and penguins to dogs and monkeys? Two UC Berkeley scientists, Michael Nachman and postdoctoral fellow Michael Sheehan, analyzed human faces and the genes that code for facial features and found a high variability that could only be explained by selection for variable faces, probably because of the importance of social interactions in human relationships and the need for humans to be recognizable.
National Institutes of Health

Contact: Robert Sanders
rlsanders@berkeley.edu
510-643-6998
University of California - Berkeley

Public Release: 16-Sep-2014
Translational Psychiatry
First blood test to diagnose depression in adults
The first blood test to diagnose major depression in adults has been developed, providing the first objective, scientific diagnosis for depression. The test also predicts who will benefit from cognitive behavioral therapy, offering the opportunity for more effective, individualized therapy. The test also showed the biological effects of the therapy, the first measurable, blood-based evidence of the therapy's success and showed who is vulnerable to recurring episodes of depression.
National Institutes of Health

Contact: Marla Paul
marla-paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 16-Sep-2014
Radiology
Imaging identifies asymptomatic people at risk for stroke
Imaging can be a cost-effective way to identify people at risk for stroke who might benefit from aggressive intervention, according to a new modeling study.
National Institutes of Health

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

Public Release: 15-Sep-2014
Psychological Science
Study first to use brain scans to forecast early reading difficulties
UC San Francisco researchers have used brain scans to predict how young children learn to read, giving clinicians a possible tool to spot children with dyslexia and other reading difficulties before they experience reading challenges.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, Flora Family Foundation, UCSF Catalyst Award, UCSF Resource Allocation Program, Brain & Behavior Research Foundation Young Investigator Award, Stanford University Lucile

Contact: Juliana Bunim
juliana.bunim@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 15-Sep-2014
Cell
Scientists discover RNA modifications in some unexpected places
Deploying sophisticated high-throughput sequencing technology, dubbed ψ-seq, a team of Whitehead Institute and Broad Institute researchers collaborated on a comprehensive, high-resolution mapping of ψ sites that confirms pseudouridylation, among the most common post-transcriptional modifications, does indeed occur naturally in mRNA.
National Institutes of Health, NIH/National Human Genome Research Institute, Howard Hughes Medical Institute, Broad Institute Funds, Marie Curie IOF, Swiss National Science Foundation

Contact: Matt Fearer
fearer@wi.mit.edu
617-452-4630
Whitehead Institute for Biomedical Research

Public Release: 15-Sep-2014
Human Molecular Genetics
Researcher develops and proves effectiveness of new drug for spinal muscular atrophy
According to recent studies, approximately one out of every 40 individuals in the United States is a carrier of the gene responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles to weaken over time. Now, researchers at the University of Missouri have made a recent breakthrough with the development of a new compound found to be highly effective in animal models of the disease. In April, a patent was filed for the compound for use in SMA.
National Institutes of Health

Contact: Jeff Sossamon
sossamonj@missouri.edu
573-882-3346
University of Missouri-Columbia

Public Release: 15-Sep-2014
Journal of Biological Chemistry
Drug's effect on Alzheimer's may depend on severity of disease
A cancer drug that has shown promise against Alzheimer's disease in mice and has begun early clinical trials has yielded perplexing results in a novel mouse model of AD that mimics the genetics and pathology of the human disease more closely than any other animal model.
NIH/National Institute on Aging, UIC Center for Clinical and Translational Science

Contact: Sharon Parmet
sparmet@uic.edu
312-413-2695
University of Illinois at Chicago

Public Release: 15-Sep-2014
Nature
X-rays unlock a protein's SWEET side
Understanding just how sugar makes its way into the cell could lead to the design of better drugs for diabetes patients and an increase in the amount of fruits and vegetables farmers are able to grow. Stanford University researchers have recently uncovered one of these 'pathways' into the cell by piecing together proteins slightly wider than the diameter of a strand of spider silk.
US Department of Energy, National Institutes of Health, NIH/National Institute of General Medical Sciences

Contact: Tona Kunz
tkunz@anl.gov
630-252-5560
DOE/Argonne National Laboratory

Public Release: 15-Sep-2014
PLOS ONE
IU study: Combining epilepsy drug, morphine can result in less pain, lower opioid doses
Adding a common epilepsy drug to a morphine regimen can result in better pain control with fewer side effects. Moreover, the combination can reduce the dosage of the opioid needed to be effective, according to a team of pain researchers at Indiana University.
National Institutes of Health, Indiana Spinal Cord and Brain Injury Research Fund

Contact: Eric Schoch
eschoch@iu.edu
316-274-8205
Indiana University

Public Release: 15-Sep-2014
Science
Cells simply avoid chromosome confusion
Reproductive cell division has evolved a simple, mechanical solution to avoid chromosome sorting errors. This natural safeguard prevents incorrect chromosome counts and misalignments that lead to infertility, miscarriage, or congenital conditions.
Wellcome Trust, National Institutes of Health, Packard Fellowship, Ludwig Institute for Cancer Research, Sidney Kimmel Foundation

Contact: Leila Gray
leilag@uw.edu
206-685-0381
University of Washington Health Sciences/UW Medicine

Public Release: 15-Sep-2014
Proceedings of the National Academy of Sciences
Network measures predict neuropsychological outcome after brain injury
In research published online Sept. 15 in the Early Edition of the Proceedings of the National Academy of Sciences, scientists studied neurological patients with focal brain damage, and found that damage to six hub locations -- identified in a model developed at Washington University using resting state fMRI, functional connectivity analyses, and graph theory -- produced much greater cognitive impairment than damage to other locations.
National Institutes of Health, McDonnell Foundation, Simons Foundation, NIH/National Institutes of Mental Health

Contact: John Riehl
john-riehl@uiowa.edu
319-384-3109
University of Iowa Health Care

Public Release: 15-Sep-2014
Proceedings of the National Academy of Sciences
Neuroscientists identify key role of language gene
Neuroscientists have found that a gene mutation that arose more than half a million years ago may be key to humans' unique ability to produce and understand speech.
Nancy Lurie Marks Family Foundation, Simons Foundation, National Institutes of Health, Wellcome Trust, Foundation pour la Recherche Medicale, Max Planck Society

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Public Release: 15-Sep-2014
American Journal of Pathology
Predicting prostate cancer: Pitt-developed test identifies new methods for treatment
A genetic discovery out of the University of Pittsburgh School of Medicine is leading to a highly accurate test for aggressive prostate cancer and identifies new avenues for treatment.
National Institutes of Health, American Cancer Society, University of Pittsburgh Cancer Institute

Contact: Allison Hydzik
HydzikAM@upmc.edu
412-647-9975
University of Pittsburgh Schools of the Health Sciences

Public Release: 15-Sep-2014
ASTRO's 56th Annual Meeting
Study adds to cancer-fighting promise of combined immunotherapy-radiation treatment
A study in mice implanted with breast and melanoma cancers adds to a growing body of evidence that highly focused radiation -- long thought to suppress immunity -- can actually help boost the immune system's fight against cancer when combined with a new kind of immune-enhancing drug.
American Association of Therapeutic Radiation Oncology, NIH/National Cancer Institute

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 15-Sep-2014
Advances in Nutrition
Vitamin E intake critical during 'the first 1,000 days'
Amid conflicting reports about the need for vitamin E and how much is enough, a new analysis published today suggests that adequate levels of this essential micronutrient are especially critical for the very young, the elderly, and women who are or may become pregnant.
National Institutes of Health

Contact: Maret Traber
maret.traber@oregonstate.edu
541-737-7977
Oregon State University

Public Release: 15-Sep-2014
American Journal of Psychiatry
Schizophrenia not a single disease but multiple genetically distinct disorders
New research shows that schizophrenia isn't a single disease but a group of eight genetically distinct disorders, each with its own set of symptoms. The finding could be a first step toward improved diagnosis and treatment for the debilitating psychiatric illness. The research at Washington University School of Medicine in St. Louis is reported online Sept. 15 in the American Journal of Psychiatry.
NIH/National Institute of Mental Health, Spanish Ministry of Science and Technology, R.L. Kirchstein National Research Award, and others

Contact: Elizabethe Holland Durando
elizabethe.durando@wustl.edu
314-286-0119
Washington University School of Medicine

Public Release: 15-Sep-2014
Proceedings of the National Academy of Sciences
Cancer and the immune system: A double-edged sword
During cancer development, tumor cells decorate their surfaces with sugar compounds called glycans that are different from those found on normal, healthy cells. Researchers at the University of California, San Diego School of Medicine report that sialic acids at the tips of these cancer cell glycans are capable of engaging with immune system cells and changing the latter's response to the tumor -- for good and bad.
Swiss National Science Foundation, Samuel and Ruth Engelberg Cancer Research Institute, National Institutes of Health

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 15-Sep-2014
American Journal of Psychiatry
To curb violent tendencies, start young
Aggressive children are less likely to become violent criminals or psychiatrically troubled adults if they receive intensive early intervention, say a new study based on more than two decades of research. The study from researchers at Duke and three other universities provides some of the strongest evidence yet that violent tendencies can be curbed.
NIH/National Institute of Mental Health, US Department of Education, NIH/National Institute on Drug Abuse

Contact: Alison Jones
Alison.jones@duke.edu
919-681-8504
Duke University

Public Release: 15-Sep-2014
Proceedings of the National Academy of Sciences
Slow to mature, quick to distract: ADHD study finds slower development of connections
A peek inside the brains of more than 750 children and teens reveals a key difference in brain architecture between those with attention deficit hyperactivity disorder and those without. Kids and teens with ADHD, a new study finds, lag behind others of the same age in how quickly their brains form connections within, and between, key brain networks.
National Institutes of Health, University of Michigan, John Templeton Foundation

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 15-Sep-2014
Clinical Cancer Research
New knowledge of genes driving bladder cancer points to targeted treatments
A collaborative study between researchers at the University of Colorado Cancer Center and the National Cancer Institute published today in the journal Clinical Cancer Research identifies BAP1 mutations in bladder cancer and also, independently, TERT mutations, implying two 'causes' of two distinct types of bladder cancer.
National Institutes of Health, NIH/National Cancer Institute-Intramural Support Program

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 15-Sep-2014
Journal of Studies on Alcohol and Drugs
Marijuana users who feel low get high
Adolescents and young adults who smoke marijuana frequently may attempt to manage negative moods by using the drug, according to a study in September's Journal of Studies on Alcohol and Drugs.
NIH/National Institute on Drug Abuse, NIH/National Institutes of Health

Contact: Erin Tornatore
erin.tornatore@childrens.harvard.edu
617-919-3110
Journal of Studies on Alcohol and Drugs

Public Release: 15-Sep-2014
Nature Chemical Biology
UK study identifies molecule that induces cancer-killing protein
A new study by University of Kentucky researchers has identified a novel molecule named Arylquin 1 as a potent inducer of Par-4 secretion from normal cells. Par-4 is a protein that acts as a tumor suppressor, killing cancer cells while leaving normal cells unharmed.
NIH/National Cancer Institute, NIH/National Center for Research Resources, UK Center for Clinical and Translational Science

Contact: Allison Perry
allison.perry@uky.edu
859-323-2399
University of Kentucky

Showing releases 176-200 out of 3488.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>

     
   

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