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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 201-225 out of 3685.

<< < 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 > >>

Public Release: 6-Nov-2015
Moffitt's Physical Sciences -- Oncology Center receives $10.4 million grant
Moffitt Cancer Center was awarded a $10.4 million grant from the National Cancer Institute for its Physical Science -- Oncology Centers.
NIH/National Cancer Institute

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 6-Nov-2015
American Journal of Pathology
Genetic modification shows promise for preventing hereditary hearing loss
A mitochondrial defect is responsible for a type of human hereditary deafness that worsens over time and can lead to profound hearing loss. Using a genetically modified mice model with a mitochondrial dysfunction that results in a similar premature hearing loss, researchers showed that precise genetic reduction of an enzyme, AMP kinase, can rescue the hearing loss. Their results are reported in the American Journal of Pathology.
National Institutes of Health, Yale Claude D. Pepper Older American Independence Center, European Molecular Biology Organization

Contact: Eileen Leahy
Elsevier Health Sciences

Public Release: 6-Nov-2015
Drug protects fertility and may prolong life in chemo-treated mice
A University of Wisconsin-Madison physician and her research team have shown that a heart medication can prevent ovarian damage and improve survival in adolescent mice after chemotherapy. The treatment also increased the number of their healthy offspring.
Wisconsin Alumni Research Foundation, National Institutes of Health, University of Wisconsin Carbone Cancer Center

Contact: Sana Salih
University of Wisconsin-Madison

Public Release: 6-Nov-2015
Nature Communications
New way to find DNA damage
University of Utah chemists devised a new way to detect chemical damage to DNA that sometimes leads to genetic mutations responsible for many diseases, including various cancers and neurological disorders.
National Institutes of Health

Contact: Lee J. Siegel
University of Utah

Public Release: 5-Nov-2015
Chemistry & Biology
Temple researchers: Small molecule inhibitor shows promise in precision cancer targeting
Cancer cells with BRCA1 or BRCA2 gene mutations are key targets for cancer therapeutics. Yet, few agents can selectively eliminate cells deficient in BRCA, and none can do so without the risk of inducing drug resistance. Lewis Katz School of Medicine at Temple University scientists think they can help overcome that problem, thanks to their discovery of a molecule that selectively kills BRCA-deficient cancer cells by blocking the activity of an alternative DNA repair pathway.
DOD/Breast Cancer Breakthrough Award, National Institutes of Health

Contact: Jeremy Walter
Temple University Health System

Public Release: 5-Nov-2015
The astounding genome of the dinoflagellate
Dinoflagellates live free-floating in the ocean or symbiotically with corals, serving up -- or as -- lunch to a host of mollusks, tiny fish and coral species. But when conditions are wrong, dinoflagellates poison shellfish beds with red tides and abandon coral reefs to a slow, bleached death. Globally, this is happening more and more often. Seeking answers, a team of researchers sequenced the complete genome of a dinoflagellate species for the first time.
Natural Science Foundation of China, National Science Foundation, National Institutes of Health, National Science and Engineering Research Council of Canada

Contact: Kim Krieger
University of Connecticut

Public Release: 5-Nov-2015
New England Journal of Medicine
TCGA findings provide molecular background for second most common kidney cancer
Scientists with the Cancer Genome Atlas, a National Institutes of Health-funded project, have molecularly characterized two types of the second most common kidney cancer and classified several subtypes of the disease.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute

Contact: Beth Hinshaw Hall
Van Andel Research Institute

Public Release: 5-Nov-2015
Study explores nicotine patch to treat memory loss
Vanderbilt University Medical Center has received a $9.4 million grant from the National Institute on Aging (NIA) to test the effectiveness of a transdermal nicotine patch in improving memory loss in older adults with mild cognitive impairment, a precursor to Alzheimer's disease.
NIH/National Institute on Aging

Contact: Craig Boerner
Vanderbilt University Medical Center

Public Release: 5-Nov-2015
Study: Strength of brain connectivity varies with fitness level in older adults
A new study shows that age-related differences in brain health -- specifically the strength of connections between different regions of the brain -- vary with fitness level in older adults.
NIH/National Institute on Aging, Abbott Nutrition

Contact: Sarah Banducci
University of Illinois at Urbana-Champaign

Public Release: 5-Nov-2015
Georgia State scientist gets $1.675 million to study link between cancer and DNA replication, repair
Ivaylo Ivanov, associate professor of chemistry at Georgia State University, has received a five-year, $1.675 million federal grant to study how problems with DNA replication and repair may lead to cancer susceptibility and inheritable genetic diseases.
NIH/National Institute of General Medical Sciences

Contact: LaTina Emerson
Georgia State University

Public Release: 5-Nov-2015
Teaching the blind to draw -- and do STEM
$1 million NIH technology transfer grant will speed adoption of interactive raised line graphics devices in schools that help young blind students learn to draw and, later, facilitate their taking math and science courses that require them to interact with graphics. The devices were developed by University of Vermont start-up E.A.S.Y. LLC.
National Institutes of Health

Contact: Jeff Wakefield
University of Vermont

Public Release: 5-Nov-2015
Current Biology
Lack of sleep may increase risk for diabetes, say CU Anschutz, CU-Boulder researchers
A lack of sufficient sleep reduces the body's sensitivity to insulin, impairing the ability to regulate blood sugar and increasing the risk of diabetes, according to researchers from the University of Colorado Anschutz Medical Campus and the University of Colorado Boulder.
National Institutes of Health, Howard Hughes Medical Institute with the Biological Sciences Initiative/Undergraduate Research Opportunities Program at CU-Boulder

Contact: David Kelly
University of Colorado Anschutz Medical Campus

Public Release: 5-Nov-2015
Current Biology
Freshwater fish, amphibians supercharge their ability to see infrared light?
Salmon migrating from the open ocean to inland waters do more than swim upstream. To navigate the murkier freshwater streams and reach a spot to spawn, the fish have evolved a means to enhance their ability to see infrared light.
National Institutes of Health, Research to Prevent Blindness, Air Force Office of Scientific Research

Contact: Judy Martin Finch
Washington University School of Medicine

Public Release: 5-Nov-2015
Zebrafish reveal how axons regenerate on a proper path
When peripheral nerves are damaged and their vital synaptic paths are disrupted, they have the ability to regenerate and reestablish lost connections. Using zebrafish, which are transparent at larval stages, the researchers identified key components that allows the nervous system to heal itself and literally obtain a whole new window into how axons regenerate.
National Institutes of Health

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 5-Nov-2015
Researchers identify new route for release of steroid hormones
Little is known about the mechanisms that regulate the release of steroid hormones from endocrine tissues. The commonly accepted understanding, noted in textbooks, is that simple diffusion is at work. But new research by a team led by a UC Riverside entomologist challenges this textbook view. The researchers report that in fruit flies, the focus of their study, the release of the steroid hormone 'ecdysone' is tightly regulated by signaling pathways in the cell.
Japan Society for the Promotion of Science, National Institutes of Health

Contact: Iqbal Pittalwala
University of California - Riverside

Public Release: 5-Nov-2015
Circadian clock controls insulin and blood sugar in pancreas
A new Northwestern Medicine study has pinpointed thousands of genetic pathways an internal body clock takes to dictate how and when our pancreas must produce insulin and control blood sugar, findings that could eventually lead to new therapies for children and adults with diabetes. The study revealed thousands of genes in the pancreas that the clock's transcription factors control in rhythm with the planet's daily rotation from light to dark.
National Institutes of Health

Contact: Marla Paul
Northwestern University

Public Release: 5-Nov-2015
Gut bacteria can dramatically amplify cancer immunotherapy
Introducing one type of bacteria into the digestive tracts of mice with melanoma can boost the ability of the animal's immune systems to attack tumor cells. The gains were comparable to treatment with anti-cancer drugs known as checkpoint inhibitors. The combination of bacteria and injections with anti-PD-L1 antibody nearly abolished tumor outgrowth.
Melanoma Research Alliance, National Institutes of Health

Contact: John Easton
University of Chicago Medical Center

Public Release: 5-Nov-2015
American Journal of Psychiatry
In preventing return of winter blues, talk outshines light, new study says
In the long term, cognitive behavior therapy is more effective at treating seasonal affective disorder that light therapy, considered the gold standard, a study to be published in the American Journal of Psychiatry found. Two winters after the initial treatment, 46 percent of research subjects given light therapy reported a recurrence of depression compared with 27 percent of those who were administered CBT. Depressive symptoms were also more severe for those who received light therapy.
NIH/National Institute of Mental Health

Contact: Jeff Wakefield
University of Vermont

Public Release: 5-Nov-2015
Current Biology
Watching a memory form
Neuroscientists at Rosalind Franklin University of Medicine and Science have discovered a novel mechanism for memory formation. Voltage-sensitive dye imaging of the swim motor program of the sea slug Tritonia reveals that some neurons possess characteristics that predispose them to join neural networks in which learning is taking place. The findings represent a shift from the field's long-term focus on synaptic plasticity.
National Science Foundation, National Institutes of Health

Contact: Judy Masterson
Rosalind Franklin University of Medicine and Science

Public Release: 5-Nov-2015
Estrogen receptor β helps endometrial tissue escape the immune system and cause disease
Endometriosis -- tissue usually found inside the uterus that grows outside -- thrives because of altered cellular signaling that is mediated by estrogen, said researchers from Baylor College of Medicine in a report that appears in the journal Cell.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, Clayton Foundation

Contact: Dipali Pathak
Baylor College of Medicine

Public Release: 5-Nov-2015
ASN Kidney Week 2015
New England Journal of Medicine
Early warning found for chronic kidney disease
A study in the New England Journal of Medicine shows that a simple blood test for the suPAR protein can predict a person's chances of developing chronic kidney disease five years before symptoms emerge, thus doing for kidney disease what cholesterol has done for cardiovascular disease.
National Institutes of Health

Contact: John Pontarelli
Rush University Medical Center

Public Release: 5-Nov-2015
NYU scientists find neural match for complexity of visual world
The complexity of the neural activity we use to process visual images reflects the intricacy of those images, a team of NYU scientists has found. Their study offers new insights into how our brain extracts information about our natural surroundings from the light captured by our eyes.
National Institutes of Health

Contact: James Devitt
New York University

Public Release: 4-Nov-2015
Nature Communications
Scientists uncover mechanism that propels liver development after birth
Internal organs continue to develop for months and years after birth. This critical period is full of cellular changes that transform the organization and function of most tissues. But the exact mechanisms underlying postnatal organ maturation are still a mystery. Now researchers report that liver cells utilize a mechanism called 'alternative splicing,' which alters how genes are translated into the proteins that guide this critical period of development.
National Institutes of Health, March of Dimes, Roy J. Carver Charitable Trust

Contact: Auinash Kalsotra
University of Illinois at Urbana-Champaign

Public Release: 4-Nov-2015
Journal of Neuroinflammation
Study: Brain's immune system could be harnessed to fight Alzheimer's
A new study appearing in the Journal of Neuroinflammation suggests that the brain's immune system could potentially be harnessed to help clear the amyloid plaques that are a hallmark of Alzheimer's disease.
NIH/National Institute of Aging

Contact: Mark Michaud
University of Rochester Medical Center

Public Release: 4-Nov-2015
International Journal of Gynecological Cancer
CK5 marks cisplatin-resistant ovarian cancer
A University of Colorado Cancer Center study recently published in the International Journal of Gynecological Cancer shows that protein cytokeratin 5 (CK5), known to be a marker of poor prognosis in breast cancer, also marks ovarian cancers likely to be resistant to the common chemotherapy cisplatin.
University of Colorado AMC Department of Obstetrics and Gynecology, National Institutes of Health

Contact: Garth Sundem
University of Colorado Anschutz Medical Campus

Showing releases 201-225 out of 3685.

<< < 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 > >>


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