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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 201-225 out of 3675.

<< < 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 > >>

Public Release: 9-Apr-2015
Stem cell disease model clarifies bone cancer trigger
Using induced pluripotent stem cells (iPSCs), a team led by Mount Sinai researchers has gained new insight into genetic changes that may turn a well known anti-cancer signaling gene into a driver of risk for bone cancers.
National Institutes of Health, Empire State Stem Cell Fund, University of Texas MD Anderson-China Medical University and Hospital Sister Institution Fund, National Breast Cancer Foundation

Contact: Renatt Brodsky
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 9-Apr-2015
In the sea, a deadly form of leukemia is catching
Outbreaks of leukemia that have devastated some populations of soft-shell clams along the east coast of North America for decades can be explained by the spread of cancerous tumor cells from one clam to another. Researchers call the discovery, reported in the Cell Press journal Cell on April 9, 2015, 'beyond surprising.'
Howard Hughes Medical Institute, National Institutes of Health

Contact: Joseph Caputo
Cell Press

Public Release: 9-Apr-2015
USC researcher plucks hair to grow hair
If there's a cure for male pattern baldness, it might hurt a little. A team led by USC Stem Cell Principal Investigator Cheng-Ming Chuong has demonstrated that by plucking 200 hairs in a specific pattern and density, they can induce up to 1,200 replacement hairs to grow in a mouse. These results are published in the April 9 edition of the journal Cell.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, NSC, Taipei Veterans General Hospital, National Institutes for Health, Edward Mallinckrodt Jr. Foundation, California Institutefor Regenerative Medicine, National Science Foundatio

Contact: Cristy Lytal
University of Southern California - Health Sciences

Public Release: 8-Apr-2015
Annals of Biomedical Engineering
Muscles matter in baseball injuries
A new approach to analyzing baseball-pitching biomechanics may one day give players more personalized feedback and help prevent elbow injuries. In a computer simulation study of baseball pitching, Northwestern University biomedical engineers found that the strength of the elbow muscles of a baseball pitcher likely play a bigger role in injury risk and prevention than previously thought.
National Institutes of Health, The Searle Funds of the Chicago Community Trust

Contact: Erin Spain
Northwestern University

Public Release: 8-Apr-2015
Environmental Pollution
Increase in inflammation linked to high traffic pollution for people on insulin
A two-year epidemiological study found that people on insulin living next to roads with heavy traffic had markedly increased concentration of C-reactive protein, a marker of inflammation, compared to those living in lower traffic areas. Individuals taking oral diabetes medications did not experience increases in C-reactive protein concentration.
NIH/National Institute of Aging, NIH/National Heart, Lung, and Blood Institute, NIH/National Institute of Environmental Health Sciences

Contact: Siobhan Gallagher or Jessica Holli
Tufts University, Health Sciences Campus

Public Release: 8-Apr-2015
Depressed? Apps lift mood with personalized therapy
Feeling blue or anxious? Now, there's a mobile 'therapist' designed to understand you and suggest the ideal mini-app to lift your mood. Intellicare, an NIH-funded study, is a new suite of 12 interactive mini-apps to combat depression and anxiety. The free app will suggest a simple mobile app based on your past preferences and feedback from the larger crowd of users. Mobile mental health treatment has potential to help millions who don't get adequate care.
NIH/National Institute of Mental Health

Contact: Marla Paul
Northwestern University

Public Release: 8-Apr-2015
Improved understanding of protein complex offers insight into DNA replication initiation mechanism basics
A clearer understanding of the origin recognition complex -- a protein complex that directs DNA replication -- through its crystal structure offers new insight into fundamental mechanisms of DNA replication initiation. This will also provide insight into how ORC may be compromised in a subset of patients with Meier-Gorlin syndrome, a form of dwarfism in humans.
National Institutes of Health, US Department of Energy

Contact: Tona Kunz
DOE/Argonne National Laboratory

Public Release: 8-Apr-2015
Personality and Individual Differences
Don't blame kids if they do not enjoy school, study suggests
When children are unmotivated at school, new research suggests their genes may be part of the equation.
NIH/National Institute of Child Health and Development

Contact: Stephen Petrill
Ohio State University

Public Release: 8-Apr-2015
UTMB researchers develop Ebola vaccine effective in a single dose
An interdisciplinary team from The University of Texas Medical Branch at Galveston and Profectus BioSciences, Inc. has developed a quick-acting vaccine that is both safe and effective with a single dose against the Ebola strain that killed thousands of people in West Africa last year. These findings are detailed in the new edition of Nature.
National Institutes of Health, UTMB Department of Microbiology and Immunology

Contact: Donna Ramirez
University of Texas Medical Branch at Galveston

Public Release: 8-Apr-2015
Tumor cells that mimic blood vessels could help breast cancer spread to other sites
A team of researchers from Cold Spring Harbor Laboratory and the Cancer Research UK Cambridge Institute at the University of Cambridge has shown in a mouse model that the ability of tumor cells to form tubular networks that mimic blood vessels can help drive metastasis, the spread of breast cancer to different sites in the body.
Howard Hughes Medical Institute, National Institutes of Health, Kathryn W. Davis, Hope Funds for Cancer Research, Boehringer Ingelheim Funds

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 8-Apr-2015
Health Education & Behavior
Older people can learn to spend less time sitting down
Older adults spend 8.5 waking hours a day sitting or lying down -- time linked to obesity, heart disease, diabetes, and death -- even if they're physically active at other times. A new study showed it was feasible to coach older people to spend less time sitting: an average of a half hour less per day. They reported feeling more able to accomplish everyday tasks -- and they walked faster and had fewer depression symptoms.
Group Health Research Institute, NIH/National Heart, Lung, and Blood Institute

Contact: Rebecca Hughes
Group Health Research Institute

Public Release: 8-Apr-2015
International Journal of Public Health
Case study Cabo Verde: Simulation offers policy Rx for curbing HIV
The African archipelago nation of Cabo Verde could bring its HIV epidemic under control within 10 years by ramping up a combination of four interventions already underway, according to projections from a sophisticated computer model led by Brown University public health researchers. Much of the progress could be achieved, the model predicts, by focusing the effort just on the most at-risk populations.
National Institutes of Health

Contact: David Orenstein
Brown University

Public Release: 8-Apr-2015
Journal of the National Cancer Institute
Genetic screening could improve breast cancer prevention
A test for a wide range of genetic risk factors could improve doctors' ability to work out which women are at increased risk of developing breast cancer, a major study of more than 65,000 women has shown. Improving the accuracy of risk analysis using genetic screening could guide breast cancer prevention in several ways -- for instance by offering high-risk women increased monitoring, personalized advice and preventative therapies.
Cancer Research UK, European Union, Breakthrough Breast Cancer, National Institutes of Health

Contact: Henry French
Institute of Cancer Research

Public Release: 8-Apr-2015
First look at 'wasabi receptor' brings insights for pain drug development
In a feat that would have been unachievable only a few years ago, researchers at UC San Francisco have pulled aside the curtain on a protein informally known as the 'wasabi receptor,' revealing at near-atomic resolution structures that could be targeted with anti-inflammatory pain drugs.
National Institutes of Health, UCSF Program for Breakthrough Biomedical Research

Contact: Pete Farley
University of California - San Francisco

Public Release: 8-Apr-2015
In first human study, new antibody therapy shows promise in suppressing HIV infection
In the first results to emerge from HIV patient trials of a new generation of so-called broadly neutralizing antibodies, Rockefeller University researchers have found the experimental therapy can dramatically reduce the amount of virus present in a patient's blood.
Bill and Melinda Gates Foundation Collaboration for AIDS Vaccine Discovery, NIH/Cooperative Centers on Human Immunology, National Center for Advancing Translational Science, Robertson Foundation, NIH/National Cancer Institute

Contact: Zach Veilleux
Rockefeller University

Public Release: 8-Apr-2015
Behavioral Sciences and the Law
Nearly 1 in 10 adults have impulsive anger issues and access to guns
An estimated 9 percent of adults in the US have a history of impulsive, angry behavior and have access to guns, according to a study published this month in Behavioral Sciences and the Law. The study also found that an estimated 1.5 percent of adults report impulsive anger and carry firearms outside their homes.
NIH/National Institute of Mental Health, NIH/National Institute on Drug Abuse, Substance Abuse and Mental Health Services Administration, Robert Wood Johnson Foundation, John W. Alden Trust, Elizabeth K. Dollard Trust

Contact: Samiha Khanna
Duke University Medical Center

Public Release: 7-Apr-2015
Obstetrics & Gynecology
Women, regardless of their backgrounds, seek help for the 'got to go' feeling
Regardless of their racial, ethnic, educational or socioeconomic background, women seek help for a frustrating -- and ubiquitous -- feature of becoming 'a woman of a certain age:' the need be close to the women's room.
National Institutes of Health, NIH/Institute of Diabetes and Digestive and Kidney Disease, Office of Research on Women's Health, NIH/Institute on Aging, NIH/Institute of Nursing Research

Contact: Phyllis Brown
University of California - Davis Health System

Public Release: 7-Apr-2015
BMJ Open
Are current dietary guidelines for sodium and potassium reasonable?
A recent study looked at how well people in France, Mexico, the United Kingdom and the United States are meeting World Health Organization dietary goals for limiting sodium and increasing potassium intake. The data confirm that people in all these countries eat too much sodium and not enough potassium. But they also suggest that the daily amounts proposed by WHO and other health agencies are unfeasible because the targets are so out of reach.
National Institutes of Health, University of Cambridge Centre for Diet and Activity Research, Public Health Research Centre of Excellence, British Heart Foundation, Cancer Research UK, Economic and Social Research Council, Medical Research Council, etc.

Contact: Leila Gray
University of Washington Health Sciences/UW Medicine

Public Release: 7-Apr-2015
Nature Neuroscience
The rest of the brain gets in the way
In a new study, researchers measured the connections between different brain regions as participants learned to play a simple game. The differences in neural activity between the quickest and slowest learners provide new insight into what is happening in the brain during the learning process and the role that interactions between different regions play. Their findings suggest that recruiting unnecessary parts of the brain for a given task, akin to over-thinking the problem, plays a critical role in this difference.
The John D. and Catherine T. MacArthur Foundation, Alfred P. Sloan Foundation, Army Research Laboratory, Institute for Translational Medicine and Therapeutics, National Science Foundation, National Institutes of Health, US Army Research Office

Contact: Evan Lerner
University of Pennsylvania

Public Release: 7-Apr-2015
Journals of Gerontology, Series B: Psychological and Social Sciences
Mortality and blood pressure directly linked to relationship quality
While other studies have shown that stress and negative marital quality can influence mortality and blood pressure, there has not been research that discussed how it might affect married couples over time. Using systolic blood pressure as a gauge, researchers assessed whether an individual's blood pressure is influenced by their own as well as their partner's reports of chronic stress and whether there are gender differences in these patterns.
NIH/National Institute on Aging

Contact: Molly Grote
Oxford University Press USA

Public Release: 7-Apr-2015
New model could help identify root cause of swallowing disorder
Nearly 40 percent of Americans 60 and older are living with dysphagia. Although it is a major health problem associated with aging, it is unknown whether the swallowing disorder is a natural part of healthy aging or if it is caused by an age-related disease. Researchers at the University of Missouri have established a model that identifies aging as a key factor in the development of dysphagia, which may lead to new therapeutic treatments.
NIH/National Institute on Deafness and Other Communication Disorders, NIH/National Institute of Neurological Disorders and Stroke, University of Missouri School of Medicine/Department of Otolaryngology-Head and Neck Surgery, MU PRIME, Mizzou Ad

Contact: Derek Thompson
University of Missouri-Columbia

Public Release: 7-Apr-2015
Translational Psychiatry
TSRI scientists find molecular trigger of schizophrenia-like behaviors and brain changes
Scientists at The Scripps Research Institute have identified a molecule in the brain that triggers schizophrenia-like behaviors, brain changes and global gene expression in an animal model. The research gives scientists new tools for someday preventing or treating psychiatric disorders such as schizophrenia, bipolar disorder and autism.
National Institutes of Health

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 7-Apr-2015
Journal of Clinical Investigation
Defect found in pancreatic cells could lead to new diabetes treatment
Researchers have found a cellular defect that can impair the body's ability to handle high glucose levels, pointing the way to new treatments for diabetes.
American Heart Association, National Institutes of Health

Contact: Lucky Tran, Ph.D.
Columbia University Medical Center

Public Release: 7-Apr-2015
Stem Cells
Moffitt researchers discover novel mechanism controlling lung cancer stem cell growth
Moffitt Cancer Center researchers discovered a novel mechanism that plays an important role in the maintenance of lung cancer stem cells. This finding may lead to new potential therapeutic targets.
National Institutes of Health

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 7-Apr-2015
Journal of Clinical Investigation
Gene variant and environment can boost severity of respiratory syncytial virus
A particular genetic mutation combined with an urban environment increases the risk of severe disease in children infected with respiratory syncytial virus, an international team of investigators has found.
Bill & Melinda Gates Foundation, National Institutes of Health

Contact: Craig Boerner
Vanderbilt University Medical Center

Showing releases 201-225 out of 3675.

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