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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 201-225 out of 3555.

<< < 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 > >>

Public Release: 3-Dec-2014
Science Translational Medicine
Study discovers RX approach that reduces herpes virus infection
A new study reports an effective treatment approach to inhibit and keep latent viruses like herpes simplex from reactivating and causing disease by blocking a protein which plays a major role in the initiation of infection. Current treatments require active viral replication and target late stages of infection, which has led to drug resistance. This study targeted the protein that controls how genes are turned on and off, early in the viral replication process.
National Institutes of Health, Research to Prevent Blindness, LSU Health Sciences Center New Orleans, Louisiana Lions Eye Foundation, US Food and Drug Administration

Contact: Leslie Capo
Louisiana State University Health Sciences Center

Public Release: 3-Dec-2014
Neuroscience Bulletin
Toxin from tobacco smoke could increase pain in spinal cord injury
A neurotoxin called acrolein found in tobacco smoke that is thought to increase pain in people with spinal cord injury has now been shown to accumulate in mice exposed to the equivalent of 12 cigarettes daily over a short time period.
National Institutes of Health

Contact: Emil Venere
Purdue University

Public Release: 3-Dec-2014
Science Translational Medicine
PET scans help identify effective TB drugs, says Pitt School of Medicine study
Sophisticated lung imaging can reveal whether or not a treatment drug is able to clear tuberculosis lung infection in human and macaque parallel studies, according to Pitt researchers.
NIH/National Institute of Allergy and Infectious Diseases, NIH/National Cancer Institute, Ministry of Health and Welfare, Republic of Korea, Bill and Melinda Gates Foundation

Contact: Anita Srikameswaran
University of Pittsburgh Schools of the Health Sciences

Public Release: 3-Dec-2014
Researcher works to block the blood-vessel dysfunction that occurs in diabetes
One of diabetes' dangerous consequences is dysfunction of the single-cell layer that lines our blood vessels. Too much circulating sugar and fat can leave our endothelial lining inflamed and unable to dilate properly, driving blood pressure up, which multiplies the problem and sets the stage for vascular disease. A new one-year, $100,000 grant from the Diabetic Complications Consortium of the National Institute of Diabetes and Digestive and Kidney Diseases is funding the study.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Toni Baker
Medical College of Georgia at Georgia Regents University

Public Release: 3-Dec-2014
Proceedings of the National Academy of Sciences
UNC researchers pinpoint chemo effect on brain cells, potential link to autism
University of North Carolina School of Medicine researchers have found for the first time a biochemical mechanism that could be a cause of chemo brain' -- the neurological side effects such as memory loss, confusion, difficulty thinking, and trouble concentrating that many cancer patients experience while on chemotherapy to treat tumors in other parts of the body.
National Institutes of Health, Simons Foundation, Angelman Syndrome Foundation

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 3-Dec-2014
Study set to shape medical genetics in Africa
The African Genome Variation Project has, in partnership with doctors and researchers in Ethiopia, the Gambia, Ghana, Kenya, Nigeria, South Africa and Uganda, collected genetic data from 1,800 people to produce the most comprehensive characterization of African genetic variation to date.
Wellcome Trust, The Wellcome Trust Sanger Institute, Bill and Melinda Gates Foundation, National Institutes of Health, UK Medical Research Council

Contact: Mary Clarke
Wellcome Trust Sanger Institute

Public Release: 3-Dec-2014
National Science Review
Tumor microenvironment of hepatitis B virus-associated hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is intimately associated with a chronically diseased liver tissue, with one of the most prevalent etiological factors being hepatitis B virus (HBV). Transformation of the liver in HBV-associated HCC often follows from long-term symptoms of chronic hepatitis. In a new study, scientists based in China and the US outline HBV's crucial role in modulating the accumulation of immune cells and fibroblasts, along with cytokines and growth factors, markedly influencing disease progression.
NIH/National Cancer Institute

Contact: Xiao-Fan Wang
Science China Press

Public Release: 3-Dec-2014
Cedars-Sinai Heart Institute physician-researcher awarded NHLBI grant
One of medicine's most prominent experts in sudden cardiac arrest has received a new $2.36 million grant to study how to better predict the deadly heart condition that kills an estimated 300,000 Americans each year.
NIH/National Heart, Lung, and Blood Institute

Contact: Sally Stewart
Cedars-Sinai Medical Center

Public Release: 3-Dec-2014
Brain study from UT Dallas uncovers new clues on how cues may affect memory
New research out of the University of Texas at Dallas shows that the brain activity prior to seeing an item is related to how well it is later remembered. Moreover, the researchers also found that the activity in different areas of the brain was unexpectedly related to how the information was remembered.
NIH/National Institute of Mental Health

Contact: Ben Porter
University of Texas at Dallas

Public Release: 3-Dec-2014
Solving a long-standing mystery, scientists identify principal protein sensor for touch
A team led by biologists at The Scripps Research Institute has solved a long-standing mystery in neuroscience by identifying the 'mechanoreceptor' protein that mediates the sense of touch in mammals.
National Institutes of Health

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 3-Dec-2014
Brain activity after smokers quit predicts chances of relapsing, Penn study suggests
Quitting smoking sets off a series of changes in the brain that Penn Medicine researchers say may better identify smokers who will start smoking again.
NIH/National Cancer Institute, NIH/National Institute on Drug Abuse, Pennsylvania Department of Health

Contact: Steve Graff
University of Pennsylvania School of Medicine

Public Release: 3-Dec-2014
Peptide shows great promise for treating spinal cord injury
Case Western Reserve scientists have developed a new chemical compound that shows extraordinary promise in restoring function lost to spinal cord injury. The compound, which the researchers dubbed intracellular sigma peptide, allowed paralyzed muscles to activate in more than 80 percent of the animals tested.
NIH/National Institute of Neurological Disorders and Stroke, P. Jing, R. Sr. and S. Poon, Case Western Reserve University, Unite 2 Fight Paralysis, Brumagin Memorial Fund, Spinal Cord Injury Sucks, United Paralysis Foundation, Kaneko Family Fund

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 3-Dec-2014
World's fastest 2-D camera may enable new scientific discoveries
A team of biomedical engineers at Washington University in St. Louis, led by Lihong Wang, Ph.D., the Gene K. Beare Distinguished Professor of Biomedical Engineering, has developed the world's fastest receive-only 2-D camera, a device that can capture events up to 100 billion frames per second. That's orders of magnitude faster than any current receive-only ultrafast imaging techniques, which are limited by on-chip storage and electronic readout speed to operations of about 10 million frames per second.
National Institutes of Health

Contact: Julie Flory
Washington University in St. Louis

Public Release: 2-Dec-2014
Brain Imaging and Behavior
Stroke researchers link frontal lesions with improved spatial neglect after prism therapy
Stroke researchers have found that the presence of frontal lesions predicts better functional improvement in individuals with spatial neglect who received prism adaptation therapy. 'Integrity of medial temporal structures may predict better improvement of spatial neglect with prism adaptation treatment' was published in September in the Neuroimaging and Rehabilitation Special Issue of Brain Imaging & Behavior. The authors are Peii Chen, PhD, Priyanka Shah, AM Barrett, Kelly M. Goedert and Anne L. Foundas.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of Child Health and Human Development, Kessler Foundation

Contact: Carolann Murphy
Kessler Foundation

Public Release: 2-Dec-2014
Critical Care Medicine
Regenstrief and IU study: Wake Up and Breathe program benefits ICU patients
Researchers from the Regenstrief Institute and the Indiana University Center for Aging Research report that waking intensive care unit patients and having them breathe on their own decreased both sedation levels and coma prevalence. The Wake Up and Breathe program also showed a trend toward reduced delirium in a critically ill population.
NIH/National Institute on Aging, Indiana University Health, Indiana Clinical and Translational Sciences Institute

Contact: Cindy Fox Aisen
Indiana University

Public Release: 2-Dec-2014
NIH-funded study is decoding blue light's mysterious ability to alter body's natural clock
Blue light bombards us, whether city lights, smartphones or tablets, says chemist Brian Zoltowski, Southern Methodist University, Dallas. Blue light knocks off-kilter the natural circadian clock in humans, plants and animals, and can result in health problems, sleep and mood disorders, drug addiction, crop disease, and even confused migratory animals. The National Institutes of Health has awarded a $320,500 grant to Zoltowski's lab to map the trajectory of blue lightwaves signaling the body's natural clock.
NIH/National Institute of General Medical Sciences

Contact: Margaret Allen
Southern Methodist University

Public Release: 2-Dec-2014
Identifying the cellular origin of fibrosis
Researchers from Brigham and Women's Hospital have identified what they believe to be the cells responsible for fibrosis, the buildup of scar tissue. Fibrotic diseases, such as chronic kidney disease and failure, lung disease, heart failure and cirrhosis of the liver, are estimated to be responsible for up to 45 percent of deaths in the developed world.
Harvard Stem Cell Institute, National Institutes of Health, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, American Heart Association, Deutsche Forschungsgemeinschaft

Contact: Lori J. Schroth
Brigham and Women's Hospital

Public Release: 2-Dec-2014
Cell Metabolism
Vitamin supplement successfully prevents noise-induced hearing loss
Researchers from Weill Cornell Medical College and the Gladstone Institutes have found a way to prevent noise-induced hearing loss in a mouse using a simple chemical compound that is a precursor to vitamin B3. This discovery has important implications not only for preventing hearing loss, but also potentially for treating some aging-related conditions that are linked to the same protein.
National Institutes of Health, New York State Department of Health Spinal Cord Injury Fund, Weill Cornell, Gladstone Institutes

Contact: Dana Smith
Gladstone Institutes

Public Release: 2-Dec-2014
University of Chicago to establish Genomic Data Commons
The University of Chicago is collaborating with the National Cancer Institute to establish the nation's most comprehensive computational facility that stores and harmonizes cancer genomic data generated through National Cancer Institute-funded research programs.
NIH/National Cancer Institute, Leidos Biomedical Research

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 2-Dec-2014
Journal of Neuroscience
Blows to head damage brain's 'garbage truck,' accelerate dementia
A new study out today in the Journal of Neuroscience shows that traumatic brain injury can disrupt the function of the brain's waste removal system. When this occurs, toxic proteins may accumulate in the brain, setting the stage for the onset of neurodegenerative diseases such as Alzheimer's and chronic traumatic encephalopathy.
NIH/National Institute of Neurological Disorders and Stroke, American Heart Association

Contact: Mark Michaud
University of Rochester Medical Center

Public Release: 2-Dec-2014
Cancer Prevention Research
Antacids linked to better survival in head and neck cancer
Patients with head and neck cancer who used antacid medicines to control acid reflux had better overall survival, according to a new study from the University of Michigan Comprehensive Cancer Center.
NIH/National Cancer Institute, NIH/National Institute of Dental and Craniofacial Research, American Cancer Society, University of Michigan

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 2-Dec-2014
Molecular Psychiatry
Alcohol abuse linked to newly identified gene network
Researchers at The University of Texas at Austin have identified a network of genes that appear to work together in determining alcohol dependence. The findings, which could lead to future treatments and therapies for alcoholics and possibly help doctors screen for alcoholism, resulted from comparing brain tissue of alcoholics and non-alcoholics.
National Institutes of Health, NIH/National Institute on Alcoholism and Alcohol Abuse, Alcohol Beverage Medical Research Foundation

Contact: Christine Sinatra
University of Texas at Austin

Public Release: 2-Dec-2014
Brain representations of social thoughts accurately predict autism diagnosis
Carnegie Mellon University researchers have created brain-reading techniques to use neural representations of social thoughts to predict autism diagnoses with 97 percent accuracy. This establishes the first biologically based diagnostic tool that measures a person's thoughts to detect the disorder that affects many children and adults worldwide.
NIH/National Institute of Mental Health

Contact: Shilo Rea
Carnegie Mellon University

Public Release: 2-Dec-2014
Cell Metabolism
Another case against the midnight snack
Salk researchers tinker with a time-restricted diet in mice and find that it is remarkably forgiving.
National Institutes of Health, Glenn Center for Aging, American Diabetes Association, Leona M. and Harry B. Helmsley Charitable Trust, Philippe Foundation Inc.

Contact: Kristina Grifantini
Salk Institute

Public Release: 1-Dec-2014
American Journal of Pathology
Prognostic role found for miR-21 expression in triple-negative breast cancer
'Triple-negative' breast cancer occurs in patients whose cells do not express receptors for estrogen, progesterone, and/or human epidermal growth factor receptor 2 (ER/PR/HER2). Because of the absence of these predictive biomarkers, treatment assignment can be difficult. Now, researchers report that high levels of the microRNA miR-21 in the tumor microenvironment, but not in the tumor epithelia, are associated with worse clinical outcomes for patients with triple-negative breast cancer, thus identifying a possible triple-negative breast cancer prognostic biomarker.
NIH/National Cancer Institute, NIH/National Center for Research Resources, Van Andel Research Institute, Hitchcock Foundation, Van Andel Institute Purple Community

Contact: Eileen Leahy
Elsevier Health Sciences

Showing releases 201-225 out of 3555.

<< < 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 > >>


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