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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 201-225 out of 3609.

<< < 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 > >>

Public Release: 9-Mar-2015
Nature Structural & Molecular Biology
TSRI scientists reveal structural secrets of nature's little locomotive
A team led by scientists at The Scripps Research Institute has determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical functions within cells. The complex's large size, myriad subunits and high flexibility have until now restricted structural studies to small pieces of the whole.
Damon Runyon Cancer Research Foundation, Pew Scholars program, Searle Scholars program, National Institutes of Health

Contact: Madeline McCurry-Schmidt
madms@scripps.edu
858-784-9254
Scripps Research Institute

Public Release: 9-Mar-2015
Aging Cell
Mayo Clinic and collaborators find new class of drugs that reduces aging in mice
A new class of drugs identified and validated by Mayo Clinic researchers along with collaborators at Scripps Research Institute and others, clearly reduces health problems in mice by limiting the effect of senescent cells -- cells that contribute to frailty and diseases associated with age. The researchers say this is a first step toward developing similar treatments for aging patients. Their findings appear today in the journal Aging Cell.
National Institutes of Health, Glenn Foundation, Ted Nash Long Life Foundation, Noaber Foundation

Contact: Bob Nellis
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

Public Release: 9-Mar-2015
Nature Neuroscience
Understanding how neurons shape memories of smells
In a study that helps to deconstruct how olfaction is encoded in the brain, neuroscientists at University of California, San Diego School of Medicine have identified a type of neuron that appears to help tune, amplify and dampen neuronal responses to chemosensory inputs from the nasal cavity.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 9-Mar-2015
Aging Cell
Scripps Research, Mayo Clinic scientists find class of drugs that boosts healthy lifespan
A research team from The Scripps Research Institute, Mayo Clinic and other institutions has identified a new class of drugs that in animal models dramatically slows the aging process -- alleviating symptoms of frailty, improving cardiac function and extending a healthy lifespan.
National Institutes of Health, Glenn Foundation, Clinical & Translational Science Awards

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 9-Mar-2015
Scientific Reports
'Exercise hormone' irisin may be a myth
The discovery of the 'exercise hormone' irisin and more than 170 papers about it since have been called into question by a new study showing the findings were based on flawed assay kits. An international team has found that the commercial antibodies used to measure levels of irisin in blood were poorly vetted and nonspecific. They argue that the irisin levels reported by these commercial kits were actually due to unknown blood proteins.
NIH/National Institutes of Health, Leibniz Association

Contact: Karl Bates
karl.bates@duke.edu
919-681-8054
Duke University

Public Release: 9-Mar-2015
Psychological Science
Perceptual training boosts contrast sensitivity for older adults
Older adults whose vision is affected by declining contrast sensitivity -- which is a factor in the ability to detect and resolve details in low light -- can improve their ability to see with perceptual learning training, according to researchers at UC Riverside and Brown University. The researchers also found that the perceptual learning task aimed at improving contrast sensitivity improved visual acuity as well for older and younger adults after only five days of training.
NIH/National Institute on Aging

Contact: Bettye Miller
bettye.miller@ucr.edu
951-827-7847
University of California - Riverside

Public Release: 9-Mar-2015
Stem Cells
Johns Hopkins researchers engineer custom blood cells
Researchers at Johns Hopkins have successfully corrected a genetic error in stem cells from patients with sickle cell disease, and then used those cells to grow mature red blood cells, they report. The study represents an important step toward more effectively treating certain patients with sickle cell disease who need frequent blood transfusions and currently have few options.
Maryland State Stem Cell Research Fund, NIH/National Heart, Lung and Blood Institute

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Public Release: 9-Mar-2015
JAMA Psychiatry
Mood, anxiety disorders common in Tourette patients, emerge at a young age
A new study of Tourette syndrome led by researchers from UC San Francisco and Massachusetts General Hospital has found that nearly 86 percent of patients who seek treatment for TS will be diagnosed with a second psychiatric disorder during their lifetimes, and that nearly 58 percent will receive two or more such diagnoses.
Tourette Syndrome Association, NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of Mental Health, TSA Research Fellowship, Duke Clinical Research Fellowship

Contact: Pete Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 9-Mar-2015
Current Biology
UCI study of fruit fly 'brain in a jar' reveals mechanics of jet lag
Long the stuff of science fiction, the disembodied 'brain in a jar' is providing science fact for UC Irvine researchers, who by studying the whole brains of fruit flies are discovering the inner mechanisms of jet lag.
National Institutes of Health, National Science Foundation

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine

Public Release: 9-Mar-2015
Nature Communications
Researchers map 'genomic landscape' of childhood adrenocortical tumors for the first time
In an advance that could lead to better identification of malignant pediatric adrenocortical tumors, and ultimately to better treatment, researchers have mapped the 'genomic landscape' of these rare childhood tumors. Their genomic mapping has revealed unprecedented details, not only of the aberrant genetic and chromosomal changes that drive the cancer, but the sequence of those changes that trigger it.
Washington University Pediatric Cancer Genome Project, Kay Jewelers, National Institutes of Health, NIH/National Cancer Institute, ALSAC

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
90-159-502-295
St. Jude Children's Research Hospital

Public Release: 9-Mar-2015
Substance Use and Misuse
Study shows teens and adults hazy on Washington marijuana law
Research by the University of Washington and Boys Town Research Institute found that only 57 percent of Washington parents surveyed knew the legal age for recreational marijuana use and just 63 percent knew that homegrown marijuana is illegal under the law.
NIH/National Institute on Drug Abuse

Contact: Deborah Bach
bach2@uw.edu
206-543-2580
University of Washington

Public Release: 9-Mar-2015
Journal of Clinical Investigation
From brain tumors to memory: A very multifunctional protein
A protein called BAI1 involved in limiting the growth of brain tumors is also critical for spatial learning and memory, researchers have discovered. BAI1 is part of a regulatory network neuroscientists think is connected with autism spectrum disorders.
NIH/National Cancer Institute, NIH/National Institute of Neurological Disorders and Stroke, Southeastern Brain Tumor Foundation, St. Baldricks

Contact: Quinn Eastman
qeastma@emory.edu
404-727-7829
Emory Health Sciences

Public Release: 9-Mar-2015
Psychological Science
Boosting older adults' vision through training
Just a weeks' worth of training can improve vision in older adults, according to new research in Psychological Science, a journal of the Association for Psychological Science. The findings show that training boosted older adults' sensitivity to contrast and also their ability to see things clearly at close distances.
NIH/National Institute on Aging

Contact: Anna Mikulak
amikulak@psychologicalscience.org
202-293-9300
Association for Psychological Science

Public Release: 9-Mar-2015
Proceedings of the National Academy of Sciences
First look at hospitalized Ebola survivors' immune cells could guide vaccine design
Emory/CDC researchers have obtained a first look at the immune responses in four Ebola virus disease survivors who received care at Emory University Hospital in 2014. Their findings reveal high levels of immune activation, and have implications for the current effort to develop vaccines against Ebola.
NIH/National Center for Advancing Translational Sciences, Defense Advanced Research Projects Agency

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory Health Sciences

Public Release: 9-Mar-2015
The Journal of Mental Health
African-American cancer patients' depression symptoms under-recognized, CWRU study finds
Case Western Reserve University nurse scientist Amy Zhang, who has long examined quality-of-life issues in cancer patients, wondered whether depression in African-American cancer patients has been under-recognized for treatment.Accurately assessing depression in cancer patients is difficult in general because the physical symptoms of cancer and depression -- low energy, lack of sleep and loss of appetite -- are so similar.
NIH/National Institute of Cancer

Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University

Public Release: 9-Mar-2015
Public Health Genomics
What's your genetic destiny? More than half of parents want to know disease risks
Would you want to know if you or your children had risk of hereditary cancer, a genetic risk for cardiovascular disease or carried the gene associated with developing Alzheimer's disease?
NIH/National Institute for Child Health and Human Development, University of Michigan, University of Michigan Health System

Contact: Beata Mostafavi
bmostafa@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 9-Mar-2015
Cancer Cell
Childhood leukemia study reveals disease subtypes, new treatment option
A new study of acute lymphoblastic leukemia (ALL), a blood cancer that primarily affects young children, has revealed that the disease has two distinct subtypes, and provides preliminary evidence that about 13 percent of ALL cases may be successfully treated with targeted drugs that have proved highly effective in the treatment of lymphomas in adults.
National Institutes of Health, NIH/National Cancer Institute, Hyundai Hope on Wheels, St. Baldrick's Foundation, Leukemia and Lymphoma Society, Tucker's Toy Box Foundation, William Lawrence and Blanche Hughes Foundation, and others

Contact: Pete Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 9-Mar-2015
Nature Nanotechnology
Innovative light therapy reaches deep tumors
Using a mouse model of cancer, researchers at Washington University School of Medicine in St. Louis have devised a way to apply light-based therapy to deep tissues never before accessible. Instead of shining an outside light, they delivered light directly to tumor cells, along with a photosensitive source of free radicals that can be activated by the light to destroy cancer. And they accomplished this using materials already approved for use in cancer patients.
National Institutes of Health, National Science Foundation

Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine

Public Release: 9-Mar-2015
Maternal & Child Nutrition
Pregnancy weight gain tilts the scales for child becoming obese
For the first time, researchers at Columbia University's Mailman School of Public Health studied the effects of gestational weight gain on childhood obesity risk among a multi-ethnic urban population. The researchers determined that excessive pregnancy weight gain was associated with greater overall and abdominal body fat in children and obesity at age seven. Excessive pre-pregnancy weight gain was associated with an increased risk of childhood obesity of approximately 300 percent.
NIH/National Institute of Environmental Health Sciences, US Environmental Protection Agency, Children's Environmental Health and Disease Prevention Research Centers, NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Stephanie Berger
sb2247@columbia.edu
212-305-4372
Columbia University's Mailman School of Public Health

Public Release: 9-Mar-2015
Nature Methods
Novel tool visualizes whole body SIV replication
A noninvasive PET/CT method developed by Yerkes and Georgia Tech researchers allows simian immunodeficiency virus replication to be seen in real time in non-human primates.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Lisa Newbern
lisa.newbern@emory.edu
404-727-7709
Emory Health Sciences

Public Release: 9-Mar-2015
Nature Neuroscience
Protein in the brain can 'put the brakes' on binge drinking
A new study identifies both where in the brain and how a protein in the brain, called Neuropeptide Y or NPY, can act to suppress binge alcohol drinking. These findings suggest that restoring NPY may be useful for treating alcohol use disorders and may also protect some individuals from becoming alcohol dependent.
NIH/National Institute on Alcohol Abuse and Alcoholism, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Bowles Center for Alcohol Studies

Contact: Tom Hughes
Tom.Hughes@unchealth.unc.edu
984-974-1151
University of North Carolina Health Care

Public Release: 9-Mar-2015
Nature
Go meta: New technique expands possibilities for molecular designers
Chemists at The Scripps Research Institute have developed a broadly useful technique for building new drug molecules and other chemical products.
NIH/National Institute for General Medical Sciences

Contact: Madeline McCurry-Schmidt
madms@scripps.edu
858-784-9254
Scripps Research Institute

Public Release: 9-Mar-2015
Scientific Reports
Bioengineers put human hearts on a chip to aid drug screening
UC Berkeley researchers have created a 'heart-on-a-chip' that effectively uses human cardiac muscle cells derived from adult stem cells to model how a human heart reacts to cardiovascular medications. The system could one day replace animal models to screen for the safety and efficacy of new drugs.
National Institutes of Health

Contact: Sarah Yang
scyang@berkeley.edu
510-643-7741
University of California - Berkeley

Public Release: 9-Mar-2015
Nature
Radiation plus immunotherapy combo revs up immune system to better attack melanoma, Penn study suggests
Treating metastatic melanoma with a triple threat --including radiation therapy and two immunotherapies that target the CTLA4 and PD-1 pathways -- could elicit an optimal response in more patients, one that will boost the immune system's attack on the disease, suggests a new study from a multidisciplinary team of researchers from Penn's Abramson Cancer Center published today in Nature.
Abramson Cancer Center, Melanoma Research Alliance, NIH/National Cancer Institute, Department of Defense and Basser Research Center for BRCA

Contact: Steve Graff
stephen.graff@uphs.upenn.edu
215-301-5221
University of Pennsylvania School of Medicine

Public Release: 9-Mar-2015
Nature Biotechnology
New technique can locate genes' on-off switches
Researchers at the Stowers Institute for Medical Research have developed a high-resolution method that can precisely and reliably map individual transcription factor binding sites in the genome, vastly outperforming standard techniques.
Stowers Institute for Medical Research, National Institutes of Health

Contact: Kim Bland
ksb@stowers.org
816-926-4015
Stowers Institute for Medical Research

Showing releases 201-225 out of 3609.

<< < 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 > >>

     
   

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