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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 201-225 out of 3736.

<< < 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 > >>

Public Release: 11-May-2015
Nature Genetics
New population genetics model could explain Finn, European differences
A new population genetics model developed by researchers at the University of Texas Health Science Center at Houston School of Public Health could explain why the genetic composition of Finnish people is so different from that of other European populations.
National Institutes of Health

Contact: Hannah Rhodes
Hannah.C.Rasorrhodes@uth.tmc.edu
713-500-3053
University of Texas Health Science Center at Houston

Public Release: 11-May-2015
Nature Biotechnology
Using CRISPR, biologists find a way to comprehensively identify anti-cancer drug targets
Imagine having a complete catalog of the best drug targets to hit in a deadly form of cancer. Imagine having a master catalog of such targets for all major cancers. Scientists at CSHL have published a method of doing precisely this, using the revolutionary gene-editing technology called CRISPR.
National Institutes of Health, Burroughs-Wellcome Fund, Alex's Lemonade Stand Foundation, National Cancer Center, Simons Center for Quantitative Biology

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Public Release: 11-May-2015
Nature
Repurposed anti-cholesterol drug could improve treatment-resistant anemias
Diamond Blackfan anemia (DBA), a rare inherited bone marrow failure syndrome, is usually diagnosed during childhood and is typically treated with glucocorticoids that cause a host of unwanted, often dangerous side effects. Using a mouse model, Whitehead Institute Founding Member Harvey Lodish, has now determined that combining the cholesterol-lowering drug fenofibrate with glucocorticoids could allow for dramatically lower steroid doses in the treatment of DBA and other erythropoietin-resistant anemias. These promising results are the foundation for a clinical trial that will begin soon.
DARPA, DOD/US Army Medical Research and Materiel Command, National Institutes of Health, NIH/National Heart, Lung, and Blood Institute, Diamond Blackfan Anemia Foundation, Diamond Blackfan Anemia Canada, Leukemia and Lymphoma Society

Contact: Nicole Giese Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

Public Release: 11-May-2015
Proceedings of the National Academy of Sciences
Personal microbiomes shown to contain unique 'fingerprints'
Boston-A new study shows that the microbial communities we carry in and on our bodies known as the human microbiome have the potential to uniquely identify individuals, much like a fingerprint. Harvard T.H. Chan School of Public Health researchers and colleagues demonstrated that personal microbiomes contain enough distinguishing features to identify an individual over time from among a research study population of hundreds of people. The study is the first to show that identifying people from microbiome data is feasible.
NIH/National Institute of Allergy and Infectious Diseases, NIH/National Human Genome Research Institute, NIH/National Institute of General Medical Sciences

Contact: Marge Dwyer
mhdwyer@hsph.harvard.edu
617-432-8416
Harvard School of Public Health

Public Release: 11-May-2015
Proceedings of the National Academy of Sciences
Scientists obtain precise estimates of the epigenetic mutation rate
University of Groningen scientists have obtained the first precise estimates of how often epigenetic marks that influence gene activity appear or disappear in the plant Arabidopsis thaliana, a model organism in plant biology. This paves the way to a deeper understanding of the importance of epigenetic changes in plant evolution. The work is published in the online Early Edition of the journal Proceedings of the National Academy of Sciences.
Netherlands Organization for Scientific Research, National Institutes of Health, National Science Foundation

Contact: Rene Fransen
r.fransen@rug.nl
University of Groningen

Public Release: 11-May-2015
Obstetrics & Gynecology
Survey finds miscarriage widely misunderstood
A survey of more than 1,000 US adults has found that misperceptions about miscarriage and its causes are widespread. Results of the survey, conducted by researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center, show that feelings of guilt and shame are common after a miscarriage and that most people erroneously believe that miscarriages are rare. The findings were published online today in the journal Obstetrics & Gynecology.
National Institutes of Health

Contact: Deirdre Branley
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine

Public Release: 8-May-2015
Toxicological Sciences
New method developed to assess cancer risk of pollutants
Scientists have developed a faster, more accurate method to assess cancer risk from certain common environmental pollutants.
NIH/National Institute of Environmental Health Sciences

Contact: Susan Tilton
susan.tilton@oregonstate.edu
541-737-1386
Oregon State University

Public Release: 8-May-2015
Journal of Molecular Biology
Tracking defects caused by brain tumor mutation yields insight to advance targeted therapy
St. Jude Children's Research Hospital scientists have gained ground toward developing more targeted therapies for the most common childhood brain tumor. The findings appear today in the Journal of Molecular Biology. The findings involve the DDX3X gene. In 2012, the St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project highlighted DDX3X as a promising focus for efforts to develop targeted therapies against medulloblastoma. Such treatments target the genetic mistakes that give rise to the brain tumor's four subtypes.
National Institutes of Health, ALSAC

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 8-May-2015
Psychopharmacology
TSRI scientists find hyped new recreational drug 'flakka' is as addictive as bath salts
Scientists at The Scripps Research Institute have found using animal models that the new recreational drug alpha-PVP ('flakka') seems equivalently potent as a stimulant, and therefore as addictive, as its chemical cousin MDPV -- bath salts.
National Institutes of Health

Contact: Madeline McCurry-Schmidt
madms@scripps.edu
858-784-9254
Scripps Research Institute

Public Release: 8-May-2015
Journal of Urology
Moffitt researchers work to determine why some prostate cancer patients experience more hot flashes
Androgen deprivation therapy (ADT) is a common treatment option for patients with advanced stage prostate cancer. But nearly 80 percent of patients who receive ADT report experiencing hot flashes during and after treatment. Moffitt Cancer Center researchers are working to determine what genetic factors and other characteristics might make prostate cancer patients more likely to experience hot flashes during and after therapy.
National Institutes of Health

Contact: Kim Polacek
Kim.Polacek@Moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 8-May-2015
American Journal of Geriatric Psychiatry
Post-traumatic stress disorder linked to accelerated aging
Writing in the May 7 online issue of American Journal of Geriatric Psychiatry, researchers at University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System suggest that people with PTSD may also be at risk for accelerated aging or premature senescence.
Veterans Affairs San Diego Healthcare System Center of Excellence for Stress and Mental Health, National Institutes of Health, and U.S. Department of Defense, UC San Diego Center for Healthy Aging, Sam and Rose Stein Institute for Research on Aging

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 7-May-2015
Sleep
Research shows sleep loss impedes decision making in crisis
The difference between life and death in the operating room, on the battlefield or during a police shootout often comes down to the ability to adapt to the unexpected. Sleep deprivation may make it difficult to do so, according to a Washington State University study that for the first time created a laboratory experiment that simulates how sleep loss affects critical aspects of decision making in high-stakes, real-world situations.
National Institutes of Health, Office of Naval Research

Contact: Paul Whitney, WSU Department of Psychology
paul.whitney@wsu.edu
509-335-4582
Washington State University

Public Release: 7-May-2015
Nature Structural and Molecular Biology
Alzheimer protein's structure may explain its toxicity
Researchers at the University of Illinois at Chicago have determined the molecular structure of one of the proteins in the fine fibers of the brain plaques that are a hallmark of Alzheimer's disease. This molecule, called amyloid beta-42, is toxic to nerve cells and is believed to provoke the disease cascade.
National Institutes of Health, Alzheimer's Association, Frederick National Laboratory for Cancer Research

Contact: Jeanne Galatzer-Levy
jgala@uic.edu
312-996-1583
University of Illinois at Chicago

Public Release: 7-May-2015
Cell
Rockefeller scientists resolve debate over how many bacteria fight off invaders
For years, researchers have puzzled over conflicting results about the workings of type III CRISPR-Cas systems, a type of immune system found in many species of bacteria. Some data showed that this mechanism would target the virus's DNA, while other experiments suggested it could only disable a virus once it had started replicating itself. New results suggest both mechanisms play a role.
Helmsley Charitable Trust, Searle Foundation, Rita Allen Foundation, Irma T. Hirschl Trust, Sinsheimer Foundation, National Institutes of Health

Contact: Zach Veilleux
zveilleux@rockefeller.edu
212-327-8982
Rockefeller University

Public Release: 7-May-2015
Cell
Fragments of tRNA suggest a novel mechanism for cancer progression
Researchers discover that particular genetic fragments, of a type of RNA known as transfer RNA, or tRNA, appear to be capable of reducing the growth and spread of breast cancer cells.
National Institutes of Health, US Department of Defense

Contact: Zach Veilleux
zveilleux@rockefeller.edu
212-327-8982
Rockefeller University

Public Release: 7-May-2015
American Journal of Public Health
If you want change, tell a relevant story -- not just facts
Research shows that narrative stories may help reduce ethnic health disparities.
NIH/National Cancer Institute

Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California

Public Release: 7-May-2015
Neuron
Plugging in your vision's autostabilization feature
Just like cameras with an autostabilization feature, our eyes execute an imperceptible reflex that prevents our vision from blurring when we, or our field of vision, are in motion. But before the reflex can work, the axons of specialized nerve cells must find their way from the retina to the correct part of the brain. New research describes how those axons find their way through the brain's maze of neurons to make the right connection.
NIH/National Eye Institute, Pew Charitable Trusts, Howard Hughes Medical Institute

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Public Release: 7-May-2015
Biological Psychiatry
Brandeis researchers identify potential cause of schizophrenic symptoms
At Brandeis University, researchers believe they have discovered an abnormality in the schizophrenic brain that could be responsible for many of the disease's symptoms and could provide a drug target for therapeutic treatments.
National Institutes of Health

Contact: Leah Burrows
lburrows@brandeis.edu
781-736-4027
Brandeis University

Public Release: 7-May-2015
Science
Gene expression is key to understanding differences between individuals and disease susceptibility
The Genotype-Tissue Expression project consortia, which includes scientists from the Centre for Genomic Regulation in Barcelona, have now published their results from their first pilot study in three Science papers. These finding will contribute to a better understanding of genomic variation and give us new clues about disease susceptibility.
National Institutes of Health, National Disease Research Interchange, Roswell Park Cancer Institute, Science Care Inc.

Contact: Laia Cendrós
laia.cendros@crg.eu
34-607-611-798
Center for Genomic Regulation

Public Release: 7-May-2015
Journal of Nuclear Medicine
Nuclear medicine scan could identify who might benefit from aromatase inhibitor treatment
A new, noninvasive nuclear medicine test can be used to determine whether aromatase inhibitor treatment will be effective for specific cancer patients, according to a recent study reported in the Journal of Nuclear Medicine. The research shows that a PET scan with the ligand C-11-vorozole reliably detects aromatase in all body organs -- demonstrating the value of its future use to pre-determine the effectiveness of the treatment for breast, ovarian, endometrial and lung cancer patients.
National Institutes of Health, NIH/National Institute of Alcohol Abuse and Alcoholism

Contact: Laurie Callahan
lcallahan@snmmi.org
703-652-6773
Society of Nuclear Medicine

Public Release: 7-May-2015
Sleep
Role of obesity and depression in excessive daytime sleepiness
Obesity and depression -- not only lack of sleep -- are underlying causes for regular drowsiness, according to Penn State College of Medicine researchers. They say these findings could lead to more personalized sleep medicine for those with excessive daytime sleepiness.
National Institutes of Health

Contact: Matt Solovey
msolovey@hmc.psu.edu
717-531-8606
Penn State

Public Release: 7-May-2015
Journal of Marriage and Family
When the baby comes, working couples no longer share housework equally
When highly educated, dual-career couples have their first child, both spouses think the baby increases their workloads by equal amounts -- but a new study suggests that's not true.
National Science Foundation, NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: Claire Kamp Dush
Kamp-dush.1@osu.edu
614-247-2126
Ohio State University

Public Release: 7-May-2015
Current Biology
TSRI researchers connect haywire protein to breast cancer, leukemia
A new study led by scientists at The Scripps Research Institute sheds light on the cause of some cancers, including breast cancer and leukemia. In the new study, the researchers found that too much of a key protein, called cyclin E, slows down DNA replication and introduces potentially harmful cancer-linked mutations when cells divide.
National Institutes of Health, Pew Latin American Fellows Program in the Biomedical Sciences

Contact: Madeline McCurry-Schmidt
madms@scripps.edu
858-784-9254
Scripps Research Institute

Public Release: 7-May-2015
Cell Reports
Scientists show the mammary gland 'remembers' prior pregnancy, spurring milk production
Anecdotal reports of nursing mothers have long suggested that giving milk is a lot easier in second and subsequent pregnancies, compared with a first pregnancy. Now, researchers can explain why. Their work shows the mammary gland forms a long-term memory of pregnancy that primes it to respond to the hormonal changes that announce succeeding pregnancies.
National Institutes of Health, CSHL Cancer Center

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Public Release: 7-May-2015
PLOS Pathogens
UTMB researchers devise vaccine that provides long-term protection against Chagas disease
Researchers from The University of Texas Medical Branch at Galveston have successfully tested a vaccine for Chagas disease, which is widespread in Latin America but is beginning to show up in the US -- including the Houston area.
National Institutes of Health, UTMB Sealy Center for Vaccine Development

Contact: Donna Ramirez
donna.ramirez@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston

Showing releases 201-225 out of 3736.

<< < 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 > >>

     
   

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