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Showing releases 201-225 out of 3332.

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Public Release: 2-May-2013
American Journal of Human Genetics
Gene variant appears to predict weight loss after gastric bypass
Massachusetts General Hospital researchers have identified a gene variant that helps predict how much weight an individual will lose after gastric bypass surgery, a finding with the potential both to guide treatment planning and to facilitate the development of new therapeutic approaches to treating obesity and related conditions like diabetes.
National Institutes of Health, Merck Research Laboratories, Ethicon Endo-Surgery

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital

Public Release: 2-May-2013
Environmental Health Perspectives
Troubling levels of toxic metals found in lipstick
UC Berkeley researchers found lead, cadmium, chromium, aluminum and five other metals in a sample of 32 different lipsticks and lip glosses commonly found in drugstores and department stores. Some of the metals were detected at levels that could raise potential health concerns.
National Institutes of Health, National Institute of Occupational Safety and Health Education

Contact: Sarah Yang
scyang@berkeley.edu
510-643-7741
University of California - Berkeley

Public Release: 2-May-2013
PLOS ONE
Making cancer less cancerous
Researchers at Johns Hopkins have identified a gene that, when repressed in tumor cells, puts a halt to cell growth and a range of processes needed for tumors to enlarge and spread to distant sites. The researchers hope that this so-called "master regulator" gene may be the key to developing a new treatment for tumors resistant to current drugs.
NIH/National Cancer Institute, Maryland Stem Cell Research Fund, Safeway Breast Cancer Foundation

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Public Release: 1-May-2013
The Prostate
Taking cholesterol-lowering drugs may also reduce the risk of dying from prostate cancer: Study
Men with prostate cancer who take cholesterol-lowering drugs called statins are significantly less likely to die from their cancer than men who don't take such medication, according to study led by researchers at Fred Hutchinson Cancer Research Center. The findings are published online today in The Prostate.
NIH/National Cancer Institute, Dutch Cancer Society, Prostate Cancer Foundation, Fred Hutchinson Cancer Research Center

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center

Public Release: 1-May-2013
American Journal of Medicine
Vitamin D: More may not be better
In recent years, healthy people have been bombarded by stories in the media and on health websites warning about the dangers of too-low vitamin D levels, and urging high doses of supplements to protect against everything from hypertension to hardening of the arteries to diabetes.
NIH/National Heart, Lung, and Blood Institute

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine

Public Release: 1-May-2013
Nature
Large genomic study identifies endometrial cancer subtypes, treatment opportunities
An analysis of endometrial cancers reveals genetic information that should improve diagnosis and guide treatments for women with an aggressive form of the disease.
NIH/National Cancer Institute

Contact: Caitlin Hool
hoolc@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center

Public Release: 1-May-2013
Nano Letters
Printable 'bionic' ear melds electronics and biology
Scientists at Princeton University used off-the-shelf printing tools to create a functional ear that can "hear" radio frequencies far beyond the range of normal human capability. The researchers' primary purpose was to explore an efficient and versatile means to merge electronics with tissue. The scientists used 3-D printing of cells and nanoparticles followed by cell culture to combine a small coil antenna with cartilage, creating what they term a bionic ear.
Defense Advanced Research Projects Agency, Air Force Office of Scientific Research, National Institutes of Health, Princeton Grand Challenges

Contact: John Sullivan
js29@princeton.edu
609-258-4597
Princeton University, Engineering School

Public Release: 1-May-2013
Proceedings of the National Academy of Sciences
PTSD research: Distinct gene activity patterns from childhood abuse
A study of adult civilians with PTSD (post-traumatic stress disorder) has shown that individuals with a history of childhood abuse have distinct, profound changes in gene activity patterns, compared to adults with PTSD but without a history of child abuse.
Max-Planck Society, Behrens-Weise Foundation, NIH/National Institute of Mental Health, Burroughs Wellcome Fund

Contact: Kathi Baker
kobaker@emory.edu
404-727-9371
Emory Health Sciences

Public Release: 1-May-2013
Environmental Science & Technology
Health defects found in fish exposed to Deepwater Horizon oil spill
Three years after the Deepwater Horizon oil spill in the Gulf of Mexico, crude oil toxicity continues to sicken a sentinel Gulf Coast fish species, according to new findings from a research team that includes a University of California, Davis, scientist.
National Science Foundation, Gulf of Mexico Research Initiative, National Institutes of Health

Contact: Andrew Whitehead
awhitehead@ucdavis.edu
530-754-8982
University of California - Davis

Public Release: 1-May-2013
ACS Chemical Biology
New molecule heralds hope for muscular dystrophy treatment
There's hope for patients with myotonic dystrophy, the most common form of muscular dystrophy in adults. A new small molecule developed by researchers at the University of Illinois has been shown to break up the protein-RNA clusters that cause the disease in living human cells, an important first step toward developing a pharmaceutical treatment for the as-yet untreatable disease.
National Institutes of Health

Contact: Liz Ahlberg
eahlberg@illinois.edu
217-244-1073
University of Illinois at Urbana-Champaign

Public Release: 1-May-2013
Cell
It slices, it dices, it silences: ADAR1 as gene-silencing modular RNA multitool
RNA, once considered a bit player in the grand scheme by which genes encode protein, is increasingly seen to have a major role in human genetics. In the April 25 issue of Cell, Wistar researchers report how the RNA-editing protein, ADAR1, also combines with the protein called Dicer to create microRNA and small interfering. These varieties of RNA, in turn, play a crucial role in gene regulation -- silencing or "switching off" the production of specific proteins.
National Institutes of Health

Contact: Greg Lester
glester@wistar.org
215-898-3934
The Wistar Institute

Public Release: 1-May-2013
Journal of Leukocyte Biology
Temple scientists weaken HIV infection in immune cells using synthetic agents
HIV, the virus that causes AIDS, is notorious for hiding within certain types of cells, where it reproduces at a slowed rate and eventually gives rise to chronic inflammation, despite drug therapy. But researchers at Temple University School of Medicine recently discovered that synthetic anti-inflammatory substances distantly related to the active ingredient of marijuana may be able to take the punch out of HIV while inside one of its major hideouts -- immune cells called macrophages.
National Institutes of Health

Contact: Jeremy Walter
Jeremy.Walter@tuhs.temple.edu
215-707-7882
Temple University Health System

Public Release: 1-May-2013
Nature
Scripps Research Institute scientists find dissimilar proteins evolved similar 7-part shape
Solving the structure of a critical human molecule involved in cancer, scientists at The Scripps Research Institute have found what they call a good example of structural conservation -- dissimilar genes that keep very similar shapes.
National Institutes of Health

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 1-May-2013
UCLA researchers awarded $11 million grant to develop stroke prevention interventions for minorites
UCLA researchers and their partners across Los Angeles County have been awarded an $11 million grant to fund research on community-based interventions to reduce the higher rates of stroke and death from stroke among disadvantaged populations.
National Institutes of Health, NIH/National Institute of Neurological Disorders and Stroke

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-2262
University of California - Los Angeles Health Sciences

Public Release: 1-May-2013
Biology of Blood and Marrow Transplantation
Researchers look to mathematics, nature, to understand the immune system and its role in cancer
Can patterns in tree branches or the meandering bends in a river provide clues that could lead to better cancer therapies? According to a new study from Virginia Commonwealth University Massey Cancer Center, these self-similar, repeating patterns in nature known as fractals help scientists better understand how the immune system is organized and may one day be used to help improve stem cell transplant outcomes in leukemia patients by predicting the probability of transplant complications.
NIH/National Cancer Institute

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University

Public Release: 1-May-2013
New England Journal of Medicine
Computer algorithms help find cancer connections
Using powerful algorithms developed by computer scientists at Brown University, medical researchers have assembled the most complete genetic profile yet of acute myeloid leukemia, an aggressive form of blood cancer. Findings are reported in the New England Journal of Medicine.
National Institutes of Health

Contact: Kevin Stacey
kevin_stacey@brown.edu
401-863-3766
Brown University

Public Release: 1-May-2013
Science Translational Medicine
Genetic mutation linked with typical form of migraine
A research team led by a Howard Hughes Medical Institute investigator at the University of California, San Francisco has identified a genetic mutation that is strongly associated with a typical form of migraine.
National Institutes of Health

Contact: Jennifer O'Brien
jennifer.obrien@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 1-May-2013
PLOS ONE
Study identifies genes, pathways altered during relaxation response practice
A new study from investigators at the Benson-Henry Institute for Mind/Body Medicine at Massachusetts General Hospital and Beth Israel Deaconess Medical Center finds that elicitation of the relaxation response -- a physiologic state of deep rest induced by practices such as meditation, deep breathing and prayer -- produces immediate changes in the expression of genes involved in immune function, energy metabolism and insulin secretion.
Centers for Disease Control and Prevention, NIH/National Center for Complementary and Alternative Medicine, NIH/National Center for Research Resources

Contact: Kristen Chadwick
kschadwick@partners.org
617-643-3907
Massachusetts General Hospital

Public Release: 1-May-2013
Nature
Genomics to reshape endometrial cancer treatment
The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women.
National Institutes of Health

Contact: Caroline Arbanas
arbanasc@wustl.edu
314-286-0109
Washington University School of Medicine

Public Release: 1-May-2013
New England Journal of Medicine
Scientists assemble genetic playbook for acute leukemia
team of researchers led by Washington University School of Medicine in St. Louis has identified virtually all of the major mutations that drive acute myeloid leukemia, a fast-growing blood cancer in adults that often is difficult to treat.
National Institutes of Health, Barnes-Jewish Hospital Foundation

Contact: Caroline Arbanas
arbanasc@wustl.edu
314-286-0109
Washington University School of Medicine

Public Release: 1-May-2013
Nature
Brain region may hold key to aging
While the search continues for the Fountain of Youth, researchers may have found the body's "fountain of aging": the brain region known as the hypothalamus. For the first time, scientists at Albert Einstein College of Medicine of Yeshiva University report that the hypothalamus of mice controls aging throughout the body. Their discovery of a specific age-related signaling pathway opens up new strategies for combating diseases of old age and extending lifespan. The paper was published today in the online edition of Nature.
NIH/National Institute on Aging, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, American Diabetes Association

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine

Public Release: 1-May-2013
Nature
A paradigm shift in endometrial cancer
Results from the Cancer Genome Atlas Research Network may change the way endometrial cancers are classified and provide opportunities to test new treatment protocols for patients with this cancer.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital

Public Release: 1-May-2013
Mayo Clinic Proceedings
No link between anesthesia, dementia in elderly, Mayo Clinic Study finds
Elderly patients who receive anesthesia are no more likely to develop long-term dementia or Alzheimer's disease than other seniors, according to new Mayo Clinic research. The study analyzed thousands of patients using the Rochester Epidemiology Project -- which allows researchers access to medical records of nearly all residents of Olmsted County, Minn. -- and found that receiving general anesthesia for procedures after age 45 is not a risk factor for developing dementia. The findings were published Wednesday, May 1, online in Mayo Clinic Proceedings.
Mayo Clinic, NIH/National Center for Advancing Translational Sciences

Contact: Nick Hanson
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

Public Release: 1-May-2013
PLOS ONE
Want to slow mental decay? Play a video game
A University of Iowa study shows that older people can put off the aging of their minds by playing a simple game that primes their processing speed skills. The research showed participants' cognitive skills improved in a range of functions, from improving peripheral vision to problem solving. Results published in the journal PLOS One.
National Institutes of Health

Contact: Richard Lewis
richard-c-lewis@uiowa.edu
319-384-0012
University of Iowa

Public Release: 1-May-2013
Journal of Clinical Investigation
Searching for therapeutic synergy in primary effusion lymphoma
In this issue of the Journal of Clinical Investigation, Juan Carlos Ramos and colleagues at the University of Miami used an immunocompromised mouse model of PEL to determine the efficacy of Bortezomib/Vorinostat combination therapy.
NIH/Developmental Center for AIDS Research, Dwoskin Family, Recio Foundations

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation

Showing releases 201-225 out of 3332.

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