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Showing releases 201-225 out of 3164. << < 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 > >>

Public Release: 8-Nov-2012
 Journal of Biological Chemistry
New, improved mouse model of human Alzheimer's may enable drug discovery
Researchers have developed a transgenic mouse that carries a human gene known to increase risk of Alzheimer's 15-fold. The new mouse, which mimics the genetics of the human disease more closely than any existing model, provides new evidence for the earliest cause of Alzheimer's and may prove more useful in the development of drugs to prevent or treat the disease.

Alzheimer's Association Zenith Grant, National Institutes of Health, University of Illinois
Contact: Jeanne Galatzer-Levy
jgala@uic.edu
312-996-1583
University of Illinois at Chicago
Public Release: 8-Nov-2012
 Psychonomic Bulletin and Review
'Read my lips' – it’s easier when they're your own
People can lip-read themselves better than they can lip-read others, according to a new study by Nancy Tye-Murray and colleagues from Washington University. Their work, which explores the link between speech perception and speech production, is published online in Springer's Psychonomic Bulletin & Review.

National Institutes of Health
Contact: Joan Robinson
joan.robinson@springer.com
49-622-148-78130
Springer
Public Release: 8-Nov-2012
 Journal of Adolescent Health
Are 'hookups' replacing romantic relationships on college campuses?
A new study by researchers with the Miriam Hospital in Providence, RI suggests college students are not actually hooking up as frequently as one might think.

NIH/National Institute on Alcohol Abuse and Alcoholism
Contact: Jessica Collins Grimes
jgrimes2@lifespan.org
401-793-7484
Lifespan
Public Release: 8-Nov-2012
 Environmental Health Perspectives
Chernobyl cleanup workers had significantly increased risk of leukemia
A 20-year study following 110,645 workers who helped clean up after the 1986 Chernobyl nuclear power plant accident in the former Soviet territory of Ukraine shows that the workers share a significant increased risk of developing leukemia. The results may help scientists better define cancer risk associated with low doses of radiation from medical diagnostic radiation procedures such as computed tomography scans and other sources.

NIH/National Cancer Institute
Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-4608
University of California - San Francisco
Public Release: 8-Nov-2012
 Structure
Scientists reveal key protein interactions involved in neurodegenerative disease
Scientists from the Florida campus of The Scripps Research Institute have defined the molecular structure of an enzyme as it interacts with several proteins involved in outcomes that can influence neurodegenerative disease and insulin resistance. The enzymes in question, which play a critical role in nerve cell (neuron) survival, are among the most prized targets for drugs to treat brain disorders such as Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis.

National Institutes of Health
Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute
Public Release: 8-Nov-2012
 Current Biology
UMass Amherst cell biologists identify new protein key to asymmetric cell division
Recently biologists at the University of Massachusetts Amherst led by Wei-lih Lee have identified a new molecular player in asymmetric cell division, a regulatory protein named She1 whose role in chromosome- and spindle positioning wasn't known before. Asymmetric cell division is important in the self-renewal of stem cells and because it ensures that daughter cells have different fates and functions.

NIH/National Institute of General Medical Sciences, American Heart Association
Contact: Janet Lathrop
jlathrop@admin.umass.edu
413-545-0444
University of Massachusetts at Amherst
Public Release: 8-Nov-2012
 Cell
Scientists uncover secrets of how intellect and behavior emerge during childhood
Scientists from the Florida campus of The Scripps Research Institute have shown that a single protein plays an oversized role in intellectual and behavioral development. The scientists found that mutations in a single gene, which is known to cause intellectual disability and increase the risk of developing autism spectrum disorder, severely disrupts the organization of developing brain circuits during early childhood. This study helps explain how genetic mutations can cause profound cognitive and behavioral problems.

National Institutes of Health, National Alliance for Research on Schizophrenia and Depression
Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute
Public Release: 8-Nov-2012
 Science
Corals attacked by toxic seaweed use chemical 911 signals to summon help
Corals under attack by toxic seaweed do what anyone might do when threatened -- they call for help. A study to be reported Nov. 9 in the journal Science shows that threatened corals send signals to fish "bodyguards" that quickly respond to trim back the noxious alga -- which can kill the coral if not promptly removed.

National Science Foundation, National Institutes of Health
Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology Research News
Public Release: 8-Nov-2012
 Alcoholism: Clinical & Experimental Research
Environmental factors can mitigate genetic risk for developing alcohol problems
Previous research suggests that genetic influences on drinking are moderated by environmental factors.
A new study has looked at gene-environment interactions between a functional single nucleotide polymorphism of the μ-opioid receptor gene (A118G) and the risk for developing an AUD during adolescence.
Findings confirm that environmental factors can moderate this association.

NIH/National Institute on Drug Abuse, NIH/National Institute on Alcohol Abuse and Alcoholism, Department of Veteran Affairs
Contact: Robert Miranda, Ph.D.
robert_miranda_jr@brown.edu
401-863-6658
Alcoholism: Clinical & Experimental Research
Public Release: 7-Nov-2012
 PLOS ONE
Cedars-Sinai research: Preclinical muscular dystrophy data shows promise
Cedars-Sinai Heart Institute researchers have found that an experimental compound may help stem the debilitating effects of muscular dystrophy by restoring normal blood flow to muscles affected by the genetic disorder.

National Institutes of Health, and others
Contact: Sally Stewart
Sally.stewart@cshs.org
310-248-6566
Cedars-Sinai Medical Center
Public Release: 7-Nov-2012
$9 million to investigate blood-clotting disorders
Researchers at Washington University School of Medicine in St. Louis have received a $9 million grant to investigate blood-clotting disorders. From heart attacks and strokes to uncontrolled bleeding, clotting disorders cause more deaths each year in the United States than all types of cancer combined.

NIH/National Heart, Lung, and Blood Institute
Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine
Public Release: 7-Nov-2012
 Arteriosclerosis, Thrombosis and Vascular Biology
Penn research reveals new aspect of platelet behavior in heart attacks: Clots can sense blood flow
Atherosclerosis involves the build up of fatty tissue within arterial walls, creating unstable structures known as plaques. These plaques grow until they burst, rupturing the wall and causing the formation of a blood clot within the artery. These clots also grow until they block blood flow; this can cause a heart attack.
New Penn research shows that clots forming under arterial-flow conditions have an unexpected ability to sense the surrounding blood moving over it.

National Institutes of Health
Contact: Evan Lerner
elerner@upenn.edu
215-573-6604
University of Pennsylvania
Public Release: 7-Nov-2012
Wake Forest Baptist research goes global with genetic center in India
World-renowned scientists are taking what they've learned from their multicenter research collaboration studying the health impact of fatty acids on diverse populations to set up a genetics center in India.

National Institutes of Health Fogarty Grant
Contact: Bonnie Davis
bdavis@wakehealth.edu
336-716-4977
Wake Forest Baptist Medical Center
Public Release: 7-Nov-2012
 Nature Methods
Stem cells + nanofibers = Promising nerve research
Using polymer nanofibers thinner than human hairs as scaffolds, researchers have coaxed a particular type of brain cell to wrap around nanofibers that mimic the shape and size of nerves found in the body.

Department of Veterans Affairs, US National Multiple Sclerosis Society, Harry Weaver Neuroscience Scholar Award, Paralyzed Veterans of America, NIH/National Institute of Neurological Disorders and Stroke
Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
Public Release: 7-Nov-2012
 International Journal of Cancer
Researchers explore connection between popular pain relievers, bladder cancer
Dartmouth researchers have found that duration of ibuprofen use was associated with a reduced risk of bladder cancer in patients in northern New England, which has a high mortality rate of this disease.

National Institutes of Health
Contact: Donna Dubuc
donna.m.dubuc@hitchcock.org
603-653-3615
Dartmouth-Hitchcock Medical Center
Public Release: 7-Nov-2012
 Journal of Neuroscience
New cell type developed for possible treatment of Alzheimer's and other brain diseases
UC Irvine researchers have created a new stem cell-derived cell type with unique promise for treating neurodegenerative diseases such as Alzheimer's.

National Institutes of Health, California Institute for Regenerative Medicine
Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
Public Release: 7-Nov-2012

American Heart Association 2012 Scientific Sessions
 JAMA
Bone marrow stem cells do not improve short-term recovery after heart attack
Administering stem cells derived from patients' own bone marrow either three or seven days after a heart attack is safe but does not improve heart function six months later, according to a clinical trial supported by the National Institutes of Health.

National Institutes of Health
Contact: Deborah Mann Lake
deborah.m.lake@uth.tmc.edu
713-500-3030
University of Texas Health Science Center at Houston
Public Release: 7-Nov-2012
 Journal of National Cancer Institute
Starchy, high carbohydrate diet associated with recurrence of colon cancer
Colon cancer survivors whose diet is heavy in complex sugars and carbohydrate-rich foods are far more likely to have a recurrence of the disease than are patients who eat a better balance of foods, a new study by Dana-Farber Cancer Institute researchers indicates.

NIH/National Cancer Institute, Pfizer Oncology
Contact: Anne Doerr
anne_doerr@dfci.harvard.edu
617-632-5665
Dana-Farber Cancer Institute
Public Release: 7-Nov-2012

24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
Patients with aberrations in two genes respond better to drugs blocking a well-known cancer pathway
Cancer patients with mutations or variations in two genes -- PIK3CA and PTEN -- who have failed to respond to several, standard treatments, respond significantly better to anti-cancer drugs that inhibit these genes' pathways of action, according to research presented at the 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland.

NIH/National Center for Research Resources
Contact: Emma Mason
wordmason@mac.com
ECCO-the European CanCer Organisation
Public Release: 7-Nov-2012
 Nature
A firm molecular handshake needed for hearing and balance
Researchers have mapped the precise 3-D atomic structure of a thin protein filament critical for cells in the inner ear and calculated the force necessary to pull it apart. These findings show the characteristics of the most vulnerable area of a structure called the tip link, and open avenues for research in fields related to noise-induced hearing loss and certain genetic diseases.

National Institutes of Health
Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School
Public Release: 7-Nov-2012
 Nature
Loss of essential blood cell gene leads to anemia
Researchers at Brigham and Women's Hospital have discovered a new gene that regulates hemoglobin synthesis during red blood cell formation.

Cooley's Anemia Foundation, March of Dimes Foundation, NIH/National Institute of Diabetes and Digestive and Kidney Diseases
Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital
Public Release: 7-Nov-2012
 PLOS ONE
Cell damage caused by personal lubricants does not increase HIV risk
The use of certain water-based, over-the-counter personal lubricants can dry out and irritate vaginal and rectal tissue, but does not appear to increase susceptibility to HIV, according to a laboratory study published today in PLOS ONE. Even so, say study authors affiliated with the National Institutes of Health-funded Microbicide Trials Network, more research is needed to fully understand the safety of personal lubricants and their effect on epithelial tissue.

National Institutes of Health
Contact: Clare Collins
collcx@upmc.edu
412-770-8643
Microbicide Trials Network
Public Release: 7-Nov-2012
 Arthritis & Rheumatism
Lack of vitamin D contributes to pain in black Americans with knee osteoarthritis
A new study reveals that black Americans display lower levels of vitamin D and greater pain sensitivity compared to white Americans. Findings published in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), indicate that vitamin D deficiency may be one of many factors that account for increased pain in older black Americans with knee osteoarthritis (OA).

NIH/National Institute on Aging, John A. Hartford Foundation, Mayday Fund
Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Public Release: 7-Nov-2012
 Neuron
New insight into why haste makes waste
Neural study provides new insights into how neuron activity changes when the brain is forced to make hasty decisions.

National Institutes of Health
Contact: David Salisbury
david.salisbury@vanderbilt.edu
615-343-6803
Vanderbilt University
Public Release: 7-Nov-2012
 PLOS ONE
When parasites catch viruses
A protozoan parasite causing an STD that affects a quarter of a billion people yearly is fueled in part by its own viral symbiont. Antibiotics that simply kill the parasite are not the solution.

National Institutes of Health, Harvard Catalyst Pilot Grant, Harvard Clinical and Translational Science Center, NIH/National Center of Research Resources
Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School

Showing releases 201-225 out of 3164. << < 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 > >>

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