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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 226-250 out of 3612.

<< < 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 > >>

Public Release: 10-Feb-2015
ACS Chemical Biology
Einstein scientists develop novel technique for finding drugs to combat malaria
Each year nearly 600,000 people -- mostly children under age five and pregnant women in sub-Saharan Africa -- die from malaria, caused by single-celled parasites that grow inside red blood cells. The most deadly malarial species -- Plasmodium falciparum -- has proven notoriously resistant to treatment efforts. A novel approach developed by scientists at Albert Einstein College of Medicine of Yeshiva University, researchers can readily screen thousands of drugs to find those potentially able to kill P. falciparum.
National Institutes of Health

Contact: Deirdre Branley
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine

Public Release: 10-Feb-2015
Gut
Unwanted impact of antibiotics broader, more complex than previously known
Researchers have discovered that antibiotics have an unwanted impact on the microorganisms that live in an animal's gut that's more broad and complex than previously known. A study has helped to explain these processes, which are now believed to affect everything from the immune system to glucose metabolism, food absorption, obesity, stress and behavior.
National Institutes of Health

Contact: Andrey Morgun
andriy.morgun@oregonstsate.edu
541-737-8047
Oregon State University

Public Release: 10-Feb-2015
UTSW receives key NCI funding to plan first US Center for Heavy Ion Radiation Therapy Research
The National Cancer Institute of the National Institutes of Health awarded UT Southwestern a $1 million planning grant to establish the country's first National Center for Heavy Ion Radiation Therapy.
NIH/National Cancer Institute

Contact: Lori Soderbergh
lori.soderbergh@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 10-Feb-2015
EMBO Molecular Medicine
TSRI scientists find new cellular pathway defect in cystinosis
Scientists at The Scripps Research Institute have identified a new cellular pathway that is affected in cystinosis, a rare genetic disorder that can result in eye and kidney damage. The findings could eventually lead to new drug treatments for reducing or preventing the onset of renal failure in patients.
Cystinosis Research Foundation, US Public Health Service, National Institutes of Health

Contact: Madeline McCurry-Schmidt
madms@scripps.edu
858-784-9254
Scripps Research Institute

Public Release: 10-Feb-2015
Developmental Cell
Epigenetic breakthrough: A first of its kind tool to study the histone code
University of North Carolina scientists have created a new research tool, based on the fruit fly, to help crack the histone code. This research tool can be used to better understand the function of histone proteins, which play critical roles in the regulation of gene expression in animals and plants.
National Institutes of Health, University of North Carolina

Contact: Mark Derewicz
mark.derewicz@unchealth.unc.edu
919-923-0959
University of North Carolina Health Care

Public Release: 10-Feb-2015
Temple researchers receive $7.4 million grant to explore brain impairment in HIV patients
Researchers at Temple University School of Medicine have been awarded a $7.4 million, five-year grant from the National Institute on Drug Abuse to determine how cocaine and HIV-1 interact to cause brain impairment in patients infected with HIV. Kamel Khalili, Ph.D., Chair of the Department of Neuroscience and Director of Temple's Comprehensive NeuroAIDS Center, will lead a team examining how cocaine worsens the neurological deficits that can plague HIV patients as they age.
NIH/National Institute on Drug Abuse

Contact: Jeremy Walter
Jeremy.Walter@tuhs.temple.edu
215-707-7882
Temple University Health System

Public Release: 10-Feb-2015
Journal of Neuroscience
Dartmouth study shows brain area involved in eye movements, heading
An area of the brain involved in eye movements also plays an important role in establishing our direction and navigating our environment, a Dartmouth College study finds.
NIH/National Institute of Neurological Disorders and Stroke

Contact: John Cramer
john.cramer@dartmouth.edu
603-646-9130
Dartmouth College

Public Release: 10-Feb-2015
Environmental Health Perspectives
Exposure to mercury, seafood associated with risk factor for autoimmune disease
Mercury in seafood -- even at low levels generally considered safe -- was associated with autoimmunity.
National Institutes of Health

Contact: Beata Mostafavi
bmostafa@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 10-Feb-2015
JAMA
Smartphone apps just as accurate as wearable devices for tracking physical activity
Although wearable devices have received significant attention for their ability to track an individual's physical activity, most smartphone applications are just as accurate, according to a new research letter in JAMA. The study tested 10 of the top-selling smartphone apps and devices in the United States by having 14 participants walk on a treadmill for 500 and 1,500 steps, each twice (for a total of 56 trials), and then recording their step counts.
NIH/National Institute on Aging, US Department of Veterans Affairs, Robert Wood Johnson Foundation

Contact: Anna Duerr
anna.duerr@uphs.upenn.edu
215-349-8369
University of Pennsylvania School of Medicine

Public Release: 10-Feb-2015
Journal of Neuroscience
Protein linked to longevity and enhanced cognition protects against Alzheimer's symptoms
Scientists from the Gladstone Institutes and the University of California, San Francisco report in the Journal of Neuroscience that raising levels of the life-extending protein klotho can protect against learning and memory deficits in a mouse model of Alzheimer's disease.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute on Aging, American Federation of Aging Research, MetLife/AFAR Award, S.D. Bechtel, Jr. Foundation, Coulter-Weeks Foundation, Bakar Family Foundation

Contact: Dana Smith
dana.smith@gladstone.ucsf.edu
415-734-2532
Gladstone Institutes

Public Release: 10-Feb-2015
American Journal of Transplantation
Growing number of donor hearts rejected, need for transplants rises, Stanford study finds
Surgeons and transplant centers nationwide increasingly have rejected hearts donated for transplantation despite a growing need for them, according to a new study by researchers at the Stanford University School of Medicine.
National Institutes of Health

Contact: Tracie White
traciew@stanford.edu
650-723-7628
Stanford University Medical Center

Public Release: 10-Feb-2015
Molecular Cancer Therapeutics
Lung cancer may be treatable with use of SapC-DOPS technology, research shows
A University of Cincinnati study, published in the advance online edition of the journal Molecular Cancer Therapeutics, provides hope that the therapeutic agent SapC-DOPS could be used for treatment of this cancer.
NIH/National Cancer Institute, New Drug State Key Project, University of Cincinnati College of Medicine

Contact: Katie Pence
katie.pence@uc.edu
513-558-4561
University of Cincinnati Academic Health Center

Public Release: 9-Feb-2015
Nature Communications
New screening tool could speed development of ovarian cancer drugs
Researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in the spread of ovarian cancer. Their 3-D cell culture system has enabled them to identify small molecules that can inhibit adhesion and invasion, hallmarks of cancer metastasis.
Bears Care, National Institutes of Health, NIH/National Cancer Institute, NIH/National Institute of Neurological Disorders and Stroke

Contact: John Easton
John.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Public Release: 9-Feb-2015
Cell Transplantation
Akt Pathway 'ramp ups' effects of transplanted umbilical cord cells used in stroke therapy
Researchers found that transplanted human umbilical cord blood cells (HUCBCs) are beneficial in preventing neuron loss when the Akt signaling pathway is activated by HUCBC secretions, and the subsequent Akt activation impacts a specific gene involved in reducing inflammation. A reduction in inflammation helps neural cell survival following stroke. The Akt pathway has been shown to be important because it activates the peroxiredoxin 5 (Prdx5) gene, an antioxidant enzyme that reduces hydrogen peroxide and inflammation.
National Institutes of Health

Contact: Robert Miranda
cogcomm@aol.com
Cell Transplantation Center of Excellence for Aging and Brain Repair

Public Release: 9-Feb-2015
Clinical Cancer Research
Could there be a gleevec for brain cancer?
The drug Gleevec (imatinib mesylate) is well known not only for its effectiveness against chronic myeloid leukemia (CML) and acute lymphoblastic leukemia, but also for the story behinds its development. The drug was specifically designed to target an abnormal molecule--a fusion of two normal cell proteins--that fueled a tumor's growth.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Karin Eskenazi
ket2116@columbia.edu
212-342-0508
Columbia University Medical Center

Public Release: 9-Feb-2015
Photochemical & Photobiological Sciences
NSU researchers discover DNA repair is high in heart, nonexistent in brain
Nova Southeastern University researchers recently discovered that, contrary to prior belief, tissues of different mammalian organs have very different abilities to repair damage to their DNA.
NIH/National Cancer Institute, Ruth Estrin Goldberg Foundation, and others

Contact: Jeremy Katzman, M.B.A., APR
j.katzman@nova.edu
954-661-7000
Nova Southeastern University

Public Release: 9-Feb-2015
American Journal of Physiology
LSU Health New Orleans research finds psychedelic drug prevents asthma development in mice
Research led by Charles Nichols, Ph.D., Associate Professor of Pharmacology and Experimental Therapeutics at the LSU Health New Orleans School of Medicine, has found that a psychedelic drug, (R)-DOI, prevents the development of allergic asthma in a mouse model. The effects are potent and effective at a concentration 50-100 times less than would influence behavior.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of Environmental Health Sciences, American Asthma Foundation, Heffter Research Institute

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center

Public Release: 9-Feb-2015
Proceedings of the National Academy of Sciences
Serotonin-deficient brains more vulnerable to social stress
Mice deficient in serotonin -- a crucial brain chemical implicated in clinical depression -- are more vulnerable than their normal littermates to social stressors, according to a Duke study in PNAS. Following exposure to stress, serotonin-deficient mice did not respond to the standard antidepressant Prozac. The results point to new strategies to help alleviate treatment-resistant depression.
National Institutes of Health, Lennon Family Foundation, Duke University's Trinity College of Arts and Sciences, Duke Institute for Brain Sciences

Contact: Karl Bates
karl.bates@duke.edu
919-681-8054
Duke University

Public Release: 9-Feb-2015
Proceedings of the National Academy of Sciences
Nano-antioxidants prove their potential
Injectable nanoparticles that could protect an injured person from further damage due to oxidative stress have proven to be astoundingly effective in tests to study their mechanism.
DOD/Mission Connect Mild Traumatic Brain Injury Consortium, NIH/National Institutes of Health, Alliance for NanoHealth, UTHealth

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Public Release: 9-Feb-2015
NIH awards IU team $3.3 million in fight against antibiotic resistance
The alarming increase of antibiotic-resistant bacteria poses health and economic threats worldwide, with more than 2 million Americans infected by the bacteria each year. Now, a team of Indiana University chemists and biologists has been awarded a major grant to develop and use a chemical tagging method to better understand how bacteria build their cell wall, which is still the best target for new antibiotics.
National Institutes of Health

Contact: Steve Chaplin
stjchap@iu.edu
812-856-1896
Indiana University

Public Release: 9-Feb-2015
NIH grant will help understanding how connections rewire after spinal cord injury
With a nearly $1.7 million grant from the National Institutes of Health, Shelly Sakiyama-Elbert, Ph.D., at Washington University in St. Louis, is using novel methods to take a closer look at how nerve cells grow and make new connections that could restore function and movement in people with spinal cord injuries.
National Institutes of Health

Contact: Julie Flory
julie.flory@wustl.edu
314-935-5408
Washington University in St. Louis

Public Release: 9-Feb-2015
A pediatric diabetes gamechanger
UCSB and Yale University researchers receive a grant to develop an artificial pancreas for the management of Type 1 diabetes in children.
National Institutes of Health

Contact: Sonia Fernandez
sonia.fernandez@ucsb.edu
805-893-4765
University of California - Santa Barbara

Public Release: 9-Feb-2015
Annals of Internal Medicine
Lung screening guidelines improve on study findings
A set of guidelines developed to help standardized lung cancer screening would have generated considerably fewer false-positives than the National Lung Screening Trial produced, according to a new retrospective study.
National Institutes of Health

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 9-Feb-2015
Nature Genetics
Inherited gene variations tied to treatment-related hearing loss in cancer patients
St. Jude Children's Research Hospital investigators have discovered inherited genetic variations that are associated with rapid hearing loss in young cancer patients treated with the drug cisplatin. The research appears in the current online issue of the scientific journal Nature Genetics.
National Institutes of Health, ALSAC

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 9-Feb-2015
Journal of Experimental Medicine
How tumor-causing cells are recruited in cancers linked to chronic inflammation
Chronic inflammation is directly associated with several types of cancer, yet the reasons as to why this happens at a cellular level remain unclear. Now, an international team of scientists led by researchers at The Wistar Institute has identified a multistep process showing not only how these cancers develop but also potentially discovering new therapeutic targets that could halt the formation and progression of tumor cells.
National Institutes of Health

Contact: Ben Leach
bleach@wistar.org
215-495-6800
The Wistar Institute

Showing releases 226-250 out of 3612.

<< < 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 > >>

     
   

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