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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 226-250 out of 3399.

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Public Release: 31-Mar-2014
BJU International
Certain genetic variants may identify patients at higher risk of bladder cancer recurrence
A new study by Dartmouth researchers suggests that certain inherited DNA sequences may affect a bladder cancer patient's prognosis. These findings may help physicians identify sub-groups of high risk bladder cancer patients who should receive more frequent screenings and aggressive treatment and monitoring.
NIH/National Cancer Institute, National Institutes of Health

Contact: Robin Dutcher
The Geisel School of Medicine at Dartmouth

Public Release: 31-Mar-2014
Nature Materials
New Penn-designed gel allows for targeted therapy after heart attack
Each patient responds to heart attacks differently and damage can vary from one part of the heart muscle to another. Penn researchers have now developed a way to address this variation via a material that can be applied directly to damaged heart tissue.
National Institutes of Health, Veterans' Affairs Health Administration

Contact: Evan Lerner
University of Pennsylvania

Public Release: 31-Mar-2014
BUSM study finds increasing health coverage does not improve readmission rates
In a first of its kind retrospective study, Boston University School of Medicine researchers have found that providing health insurance coverage to previously uninsured people does not result in reducing 30-day readmission rates. The study, which appears in the British Medical Journal, used data on actual (versus self-reported) use of care and also found no change in racial/ethnic disparities in this outcome, despite a markedly higher baseline of uninsurance among African-American and Hispanics in Massachusetts.
National Institutes of Health, Rx foundation, Senior Research Career Scientist

Contact: Gina DiGravio
Boston University Medical Center

Public Release: 31-Mar-2014
Proceedings of the National Academy of Sciences
Possible explanation for human diseases caused by defective ribosomes
Mutations in proteins that make ribosomes cause disorders called 'ribosomopathies,' which are characterized by bone marrow failure and anemia early in life, followed by elevated cancer risk in middle age. How can ribosomopathies first appear as diseases caused by too few cells, but later turn into diseases caused by too many cells? This paradox has puzzled the scientific community. A new study suggests ribosomopathies are caused by a sequence of mistakes at the molecular level.
National Institutes of Health

Contact: Heather Dewar
University of Maryland

Public Release: 31-Mar-2014
Proceedings of the National Academy of Sciences
Experimental cancer drug reverses schizophrenia in adolescent mice
Johns Hopkins researchers say that an experimental anticancer compound appears to have reversed behaviors associated with schizophrenia and restored some lost brain cell function in adolescent mice with a rodent version of the devastating mental illness.
NIH/National Institute of Mental Health, Maryland Stem Cell Research Fund, and others

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 31-Mar-2014
Oncology Nursing Forum
Mobile tools boost tobacco screening and cessation counseling
Smartphones and tablets may hold the key to getting more clinicians to screen patients for tobacco use and advise smokers on how to quit. Even though tobacco use is the leading cause of preventable disease and death in the US, clinicians often don't ask about smoking during patient exams.
NIH/National Cancer Institute, NIH/National Institute of Nursing Research

Contact: Lisa Rapaport
Columbia University Medical Center

Public Release: 31-Mar-2014
Burden of diabetic ketoacidosis still unacceptably high
Diabetic ketoacidosis, a life-threatening but preventable condition, remains an important problem for youth with diabetes and their families.
Center for Disease Control Division of Diabetes Translation, National Institutes of Health

Contact: Jackie Brinkman
University of Colorado Denver

Public Release: 31-Mar-2014
Proceedings of the National Academy of Sciences
Self-healing engineered muscle grown in the laboratory
Biomedical engineers at Duke University have grown living skeletal muscle that contracts powerfully and rapidly, integrates quickly into mice, and for the first time, demonstrates the ability to heal itself both inside the laboratory and inside an animal.
National Science Foundation, NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Ken Kingery
Duke University

Public Release: 31-Mar-2014
Circulation: Journal of the American Heart Association
Heart health as young adult linked to mental function in mid-life
Having blood pressure, blood sugar and cholesterol levels slightly higher than the recommended guidelines in early adulthood is associated with lower cognitive function in mid-life.
NIH/National Heart, Lung, and Blood Institute, Kaiser Foundation Research Institute

Contact: Darcy Spitz
American Heart Association

Public Release: 31-Mar-2014
Annals of Internal Medicine
Johns Hopkins study shows link between HIV infection and coronary artery disease
Men with long-term HIV infections are at higher risk than uninfected men of developing plaque in their coronary arteries, regardless of their other risk factors for coronary artery disease, according to results of a study led by Johns Hopkins researchers. A report on the research appears in the April 1 issue of Annals of Internal Medicine.
NIH/National Heart, Lung and Blood Institute, NIH/National Center for Advancing Translational Science

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 31-Mar-2014
Proceedings of the National Academy of Sciences
Computer maps 21 distinct emotional expressions -- even 'happily disgusted'
Researchers at The Ohio State University have found a way for computers to recognize 21 distinct facial expressions -- even expressions for complex or seemingly contradictory emotions such as 'happily disgusted' or 'sadly angry.' The study more than triples the number of documented facial expressions that researchers can now use for cognitive analysis.
National Institutes of Health

Contact: Pam Frost Gorder
Ohio State University

Public Release: 31-Mar-2014
Journal of General Physiology
Researchers reveal a new pathway through the sodium pump
The ubiquitous sodium pump appears to be more versatile than we thought. In addition to its role as a sodium and potassium ion transporter, researchers now show that the pump can simultaneously import protons into the cell. The study not only provides evidence of 'hybrid' function by the pump, it also raises important questions about whether the inflow of protons through sodium pumps might play a role in certain pathologies, including heart attack and stroke.
National Institutes of Health

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 30-Mar-2014
Nature Methods
Scripps Florida scientists offer 'best practices' nutrition measurement for researchers
Scientists from the Florida campus of the Scripps Research Institute have developed what amounts to a best practices guide to the most accurate way of measuring fruit fly food consumption.
National Institutes of Health, Glenn Foundation for Medical Research, Ellison Medical Foundation

Contact: Mika Ono
Scripps Research Institute

Public Release: 30-Mar-2014
Nature Biotechnology
Erasing a genetic mutation
An MIT team reverses a liver disorder in mice by correcting a mutated gene.
NIH/National Cancer Institute, National Institutes of Health, Marie D. and Pierre Casimir-Lambert Fund

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 30-Mar-2014
Nature Neuroscience
A new approach to Huntington's disease?
Tweaking a specific cell type's ability to absorb potassium in the brain improved walking and prolonged survival in a mouse model of Huntington's disease, reports a University of California Los Angeles study published March 30 in the online edition of Nature Neuroscience. The discovery could point to new drug targets for treating the devastating disease, which strikes one in every 20,000 Americans.
CHDI Foundation, NIH/National Institute of Mental Health, NIH/National Institute of Neurological Disorders and Stroke

Contact: Elaine Schmidt
University of California - Los Angeles Health Sciences

Public Release: 28-Mar-2014
Whether they reduce fat or not, obesity programs lower kids' blood pressure
A systematic review and meta-analysis of published studies of the effect of child obesity intervention programs on blood pressure has found that whether such programs prevented obesity or not, many of them reduced blood pressure in children.
National Institutes of Health

Contact: Pat Donovan
University at Buffalo

Public Release: 28-Mar-2014
Nature Communications
Researchers develop technique to measure engineered nanomaterials delivered to cells
Scientists at the Center for Nanotechnology and Nanotoxicology at Harvard School of Public Health have discovered a fast, simple, and inexpensive method to measure the effective density of engineered nanoparticles in physiological fluids, thereby making it possible to accurately determine the amount of nanomaterials that come into contact with cells and tissue in culture. The method will be published in the March 28, 2014 Nature Communications.
NIH/National Institute of Environmental Health Sciences, National Science Foundation, Harvard School of Public Health/Center for Nanotechnology and Nanotoxicology

Contact: Marge Dwyer
Harvard School of Public Health

Public Release: 28-Mar-2014
Journal of the National Cancer Institute
UNC researchers show cancer chemotherapy accelerates 'molecular aging'
Using a test developed at UNC Lineberger Comprehensive Cancer Center to determine molecular aging, UNC oncologists have directly measured the impact of anti-cancer chemotherapy drugs on biological aging.
National Institutes of Health, Paul Glenn Foundation, Burroughs Wellcome Fund, Breast Cancer Research Foundation

Contact: William Davis
University of North Carolina Health Care

Public Release: 28-Mar-2014
Journal of Pediatrics
Esophageal function implicated in life-threatening experiences in infants, study suggests
A study of apparent life-threatening events -- called ALTEs for short -- suggests that infants who experience them have abnormal regulation of esophageal and airway function compared to healthy babies. The findings, published online March 28 in the Journal of Pediatrics by a team in The Research Institute at Nationwide Children's Hospital, offer new information about the mechanisms behind ALTEs and what clinicians and parents can do to avoid them.
National Institutes of Health

Contact: Gina Bericchia
Nationwide Children's Hospital

Public Release: 27-Mar-2014
Researchers identify good bacteria that protects against HIV
Researchers at the University of Texas Medical Branch at Galveston by growing vaginal skin cells outside the body and studying the way they interact with 'good and bad' bacteria, think they may be able to better identify the good bacteria that protect women from HIV infection and other sexually transmitted infections.
University of Texas Medical Branch at Galveston/Translational Sciences, NIH/National Center for Advancing Translational Sciences, NIH/National Institute of Allergy and Infectious Diseases

Contact: Raul Reyes
University of Texas Medical Branch at Galveston

Public Release: 27-Mar-2014
The Journal of Neuroscience
Brain scans link concern for justice with reason, not emotion
People who care about justice are swayed more by reason than emotion, according to new brain scan research from the University of Chicago Department of Psychology and Center for Cognitive and Social Neuroscience.
NIH/National Institute of Mental Health, John Templeton Foundation

Contact: Jann Ingmire
University of Chicago

Public Release: 27-Mar-2014
Nature Medicine
Mechanical forces driving breast cancer lead to key molecular discovery
The stiffening of breast tissue in breast-cancer development points to a new way to distinguish a type of breast cancer with a poor prognosis from a related, but often less deadly type, UC San Francisco researchers have found in a new study.
US Department of Defense Breast Cancer Research Program, Susan G. Komen, National Institutes of Health

Contact: Jeffrey Norris
University of California - San Francisco

Public Release: 27-Mar-2014
Cancer Cell
Adult cancer drugs show promise against an aggressive childhood brain tumor
The quest to improve survival of children with a high-risk brain tumor has led St. Jude Children's Research Hospital investigators to two drugs already used to treat adults with breast, pancreatic, lung and other cancers. The study was published today online ahead of print in the journal Cancer Cell.
National Institutes of Health, French National Cancer Institute, Centre national de la recherche scientifique, Institut Curie, Necker Hospital, V Foundation, American-Lebanese-Syrian Associated Charities

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 27-Mar-2014
Proceedings of the National Academy of Science
Cancer researchers find key protein link
A new understanding of proteins at the nexus of a cell's decision to survive or die has implications for researchers who study cancer and age-related diseases.
National Institutes of Health, Cancer Prevention Research Institute of Texas, Israeli Science Foundation, European Research Council

Contact: David Ruth
Rice University

Public Release: 27-Mar-2014
Neurobiologists find chronic stress in early life causes anxiety, aggression in adulthood
In experiments to assess the impacts of social stress upon adolescent mice, both at the time they are experienced and during adulthood, a Cold Spring Harbor Laboratory team conducted many different kinds of stress tests and means of measuring their impacts. The research indicates that a 'hostile environment in adolescence disturbs psychoemotional state and social behaviors of animals in adult life,' the team says.
Russian Foundation for Basic Research, NIH/National Institute of Mental Health

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Showing releases 226-250 out of 3399.

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