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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 226-250 out of 3609.

<< < 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 > >>

Public Release: 9-Mar-2015
Nature Genetics
Fifteen new breast cancer genetic risk 'hot-spots' revealed
Scientists have discovered another 15 genetic 'hot-spots' that can increase a woman's risk of developing breast cancer, according to research published today in Nature Genetics.
Cancer Research UK, European Union, Canadian Institutes of Health Research, Ministry of Economic Development, Innovation and Export Trade of Quebec, National Institutes of Health

Contact: Liz Smith
liz.smith@cancer.org.uk
020-346-98300
Cancer Research UK

Public Release: 9-Mar-2015
JAMA Pediatrics
Youth suicide rate in rural areas is nearly double the rate in cities
The adolescent and young-adult suicide rate in the United States was almost twice as high in rural settings than in urban areas between 1996 and 2010, and new research suggests that the gap appears to be widening.
NIH/National Center for Advancing Translational Sciences

Contact: Cynthia Fontanella
Fontanella.4@osu.edu
614-293-6440
Ohio State University

Public Release: 9-Mar-2015
Nature Medicine
Novel drug candidate regenerates pancreatic cells lost in diabetes
In a screen of more than 100,000 potential drugs, only one, harmine, drove human insulin-producing beta cells to multiply.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, American Diabetes Association, Diabetes, Obesity and Metabolism Institute

Contact: Renatt Brodsky
renatt.brodsky@mountsinai.org
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 6-Mar-2015
Federal agencies award UT Arlington's TMAC $6.7 million to bolster manufacturing
UT Arlington's TMAC, formerly the Texas Manufacturing Assistance Center, has won a five-year, $33.5 million Commerce Department award to manage Manufacturing Extension Partnership centers to help small and mid-sized manufacturers across the state.
US Department of Commerce, NIH/National Institute of Standards and Technology

Contact: Herb Booth
hbooth@uta.edu
817-272-7075
University of Texas at Arlington

Public Release: 6-Mar-2015
Neuron
Feeling sleepy? Might be the melatonin
Melatonin supplements are commonly used as sleep aids; however, our bodies also make melatonin naturally, and until a recent Caltech study using zebrafish, no one knew how -- or even if -- this melatonin contributed to our natural sleep. The new work suggests that even in the absence of a supplement, naturally occurring melatonin may help us fall and stay asleep.
National Institutes of Health, Mallinckrodt Foundation, Rita Allen Foundation, Brain and Behavior Research Foundation, Della Martin Postdoctoral Fellowship

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Public Release: 6-Mar-2015
Nature Genetics
Chromosomal rearrangement is the key to progress against aggressive infant leukemia
The St. Jude Children's Research Hospital -- Washington University Pediatric Cancer Genome Project reports that a highly aggressive form of leukemia in infants has surprisingly few mutations beyond the chromosomal rearrangement that affects the MLL gene. The findings suggest that targeting the alteration is likely the key to improved survival. The research appeared online ahead of print this week in the scientific journal Nature Genetics.
Kay Jewelers, National Institutes of Health, Swedish Childhood Cancer Society, Swedish Research Council, Swedish Cancer Society, BioCARE, Gunnar Nilsson Cancer Foundation, ALSAC

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 6-Mar-2015
IUPUI study: How alcohol hijacks brain's reward system
With the support of a $545,000 three-year grant from the National Institute on Alcohol Abuse and Alcoholism, researchers from the School of Science at Indiana University-Purdue University Indianapolis are conducting research on how the brain's reward system -- the circuitry that helps regulate the body's ability to feel pleasure -- is hijacked by alcohol.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Cindy Fox Aisen
caisen@iupui.edu
317-843-2276
Indiana University-Purdue University Indianapolis School of Science

Public Release: 6-Mar-2015
Journal of Occupational and Environmental Medicine
Workplace lifestyle intervention program improves health
A healthy lifestyle intervention program administered at the workplace and developed by the University of Pittsburgh Graduate School of Public Health significantly reduces risk factors for diabetes and heart disease, according to a new study.
NIH/National Institutes of Diabetes and Digestive and Kidney Diseases

Contact: Allison Hydzik
HydzikAM@upmc.edu
412-647-9975
University of Pittsburgh Schools of the Health Sciences

Public Release: 6-Mar-2015
eLife
Experimental herpes vaccine upends traditional approach and shows promise
Scientists at Albert Einstein College of Medicine have designed a new type of vaccine that could be the first-ever for preventing genital herpes -- one of the most common sexually transmitted diseases, affecting 500 million people worldwide. Using a counterintuitive approach, researchers were able to prevent both infections caused by herpes simplex virus type 2, which causes genital herpes. Findings from the research, conducted in mice, were published today in the online journal eLife.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Deirdre Branley
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine

Public Release: 5-Mar-2015
Cell
Multitasking hunger neurons also control compulsive behaviors
In the absence of food, neurons that normally control appetite initiate complex, repetitive behaviors seen in obsessive-compulsive disorder, and anorexia nervosa, according to a new study by Yale School of Medicine researchers.
National Institutes of Health, American Diabetes Association, Helmholtz Society, Klarman Foundation, Conselho Nacional de Desenvolvimento Cientifico e Tecnologico, Brain and Behavior Research Foundation, Science Without Borders

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University

Public Release: 5-Mar-2015
ENDO 2015: The 97th Annual Meeting & EXPO in San Diego, CA
Gut bacteria may contribute to diabetes in black males
African American men at elevated risk for developing type 2 diabetes may have fewer beneficial and more harmful intestinal bacteria, according to research presented by University of Illinois at Chicago endocrinologist Dr. Irina Ciubotaru at the ENDO 2015 meeting in San Diego.
US Department of Veterans Affairs, National Institutes of Health

Contact: Sharon Parmet
sparmet@uic.edu
312-413-2695
University of Illinois at Chicago

Public Release: 5-Mar-2015
PLOS ONE
Fast food commercials to kids 'deceptive' by industry self-regulation standards
Fast food ads aimed at kids fail to de-emphasize toy premiums, making them deceptive by industry self-regulation standards. They also fail to emphasize healthy menu items, investigators at Dartmouth-Hitchcock's Norris Cotton Cancer Center have found.
Robert Wood Johnson Foundation Healthy Eating Research Program, National Institutes of Health

Contact: Kirk Cassels
603-653-6177
The Geisel School of Medicine at Dartmouth

Public Release: 5-Mar-2015
Science
Transport molecule forms a protective structure to guide proteins to cell membrane
The molecular complex that guides an important class of proteins to correct locations in cell membranes does so by forming a dimeric structure with a protective pocket. This structure shields tail-anchored membrane proteins -- which have roles in a wide variety of cellular functions from neurotransmitter release to insulin production -- from harmful aggregation or misfolding as they move through the inner environment of a cell. The findings clarify the mechanism behind a fundamental biological process.
National Institutes of Health, US Department of Energy, UK Medical Research Council, Chicago Biomedical Consortium

Contact: Kevin Jiang
kevin.jiang@uchospitals.edu
773-795-5227
University of Chicago Medical Center

Public Release: 5-Mar-2015
Neuron
Abnormal brain rhythms tied to problems with thinking in schizophrenia
By studying specially bred mice with specific developmental and cognitive traits resembling those seen in schizophrenia, UC San Francisco researchers have provided new evidence that abnormal rhythmic activity in particular brain cells contributes to problems with learning, attention, and decision-making in individuals with that disorder.
Staglin Family, International Mental Health Research Organization, NIH/National Institute of Mental Health, Alfred P. Sloan Foundation, National Institutes of Health, Brain and Behavior Research Foundation

Contact: Pete Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 5-Mar-2015
The Journals of Gerontology, Series A
If you come from a family with relatives who have lived long lives, you will too?
Recent research from the Long Life Family Study confirms that severe mortality-associated diseases are less prevalent in the families of long-lived individuals than in the general population. The Journals of Gerontology, Series A will publish these findings on March 5, 2015.
NIH/National Institute on Aging, National Institutes of Health

Contact: Tara Kennedy
tara.kennedy@oup.com
212-726-6258
Oxford University Press USA

Public Release: 5-Mar-2015
How healthy is genetically modified soybean oil?
Soybean oil accounts for more than 90 percent of all the seed oil production in the United States. Genetically modified soybean oil, made from seeds of GM soybean plants, was recently introduced into the food supply on the premise that it is healthier than conventional soybean oil. But is that premise true? Just barely, say scientists at the University of California, Riverside and their colleagues at UC Davis.
UCR Collaborative Seed Grant, UCR Agricultural Experiment Station, National Institutes of Health, National Institute of Environmental Health Sciences

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Public Release: 5-Mar-2015
Chemistry & Biology
Molecule from trees helps female mice only resist weight gain
A molecule found in some plants can combat weight gain induced by a high-fat diet, but only in female mice, not males. 7,8-dihydroxyflavone (7,8-DHF) is thought to mimic the effects of a growth factor induced by exercise.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Institute on Deafness and Other Communication Disorders

Contact: Quinn Eastman
qeastma@emory.edu
404-727-7829
Emory Health Sciences

Public Release: 5-Mar-2015
Cell
In vivo CRISPR-Cas9 screen sheds light on cancer metastasis and tumor evolution
For the first time, CRISPR-Cas9 gene-editing technology has been employed in a whole organism model to systematically target every gene in the genome. A team of scientists have pioneered the use of this technology to 'knock out,' or turn off, all genes across the genome systematically in an animal model of cancer, revealing genes involved in tumor evolution and metastasis and paving the way for similar studies in other cell types and diseases.
National Institutes of Health, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Institute of Mental Health

Contact: Paul Goldsmith
paulg@broadinstitute.org
617-714-8600
Broad Institute of MIT and Harvard

Public Release: 5-Mar-2015
Science
Yale researchers map 'switches' that shaped the evolution of the human brain
Thousands of genetic 'dimmer' switches, regions of DNA known as regulatory elements, were turned up high during human evolution in the developing cerebral cortex, according to new research from the Yale School of Medicine.
National Institutes of Health

Contact: Lindsay Borthwick
lindsay.borthwick@yale.edu
416-706-7522
Yale University

Public Release: 5-Mar-2015
American Heart Association's Epidemiology/Lifestyle Scientific Sessions 2015
Improving your fitness could improve your spouse's fitness
Your exercise regimen isn't just good for you; it may also be good for your spouse. New research led by the Johns Hopkins Bloomberg School of Public Health finds that if one spouse improves his or her exercise regimen, the other spouse is significantly more likely to follow suit.
NIH/National Heart, Lung, and Blood Institute

Contact: Stephanie Desmon
sdesmon1@jhu.edu
410-955-7619
Johns Hopkins University Bloomberg School of Public Health

Public Release: 5-Mar-2015
Cell Reports
Researchers discover protein's pivotal role in heart failure
Researchers at the University of California, San Diego School of Medicine have identified a key piece in the complex molecular puzzle underlying heart failure -- a serious and sometimes life-threatening disorder affecting more than 5 million Americans.
National Institutes of Health

Contact: Bonnie Ward
bjward@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 5-Mar-2015
Cell Stem Cell
Twin copies of gene pair up in embryonic stem cells at critical moment in differentiation
Researchers at CSHL have shown that the two alleles of Oct4, a gene important in embryonic stem cells, don't remain separate in the nucleus of stem cells but rather pair up, at the developmental point at which stem cells begin their maturation into specific cell types.
NIH/National Institute of General Medical Sciences, Starr Foundation

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Public Release: 5-Mar-2015
Journal of the National Cancer Institute
Unregulated web marketing of genetic tests for personalized cancer care raises concerns
Websites that market personalized cancer care services often overemphasize their purported benefits and downplay their limitations, and many sites offer genetic tests whose value for guiding cancer treatment has not been shown to be clinically useful, according to a new study from Dana-Farber Cancer Institute.
American Cancer Society, National Institutes of Health

Contact: Anne Doerr
anne_doerr@dfci.harvard.edu
617-632-4090
Dana-Farber Cancer Institute

Public Release: 5-Mar-2015
ENDO 2015: The 97th Annual Meeting & EXPO in San Diego, CA
Phthalates potentially alter levels of a pregnancy hormone that influences sex development
Exposure to hormone-altering chemicals called phthalates -- which are found in many plastics, foods and personal care products -- early in pregnancy is associated with a disruption in an essential pregnancy hormone and adversely affects the masculinization of male genitals in the baby, according to research led by the University of Pittsburgh Graduate School of Public Health. The findings focus on the role of the placenta in responding to these chemicals and altering levels of a key pregnancy hormone.
NIH/National Institute of Environmental Health Sciences

Contact: Allison Hydzik
Hydzikam@upmc.edu
412-647-9975
University of Pittsburgh Schools of the Health Sciences

Public Release: 5-Mar-2015
Exposure to endocrine disruptors during pregnancy affects the brain two generations later
Prenatal exposure to low doses of the environmental contaminants polychlorinated biphenyls, or PCBs, change the developing brain in an area involved in metabolism, and some effects are apparent even two generations later, a new study finds. Performed in rats, the research will be presented Friday at the Endocrine Society's 97th annual meeting in San Diego.
National Institutes of Health

Contact: Aaron Lohr
alohr@endocrine.org
202-971-3654
The Endocrine Society

Showing releases 226-250 out of 3609.

<< < 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 > >>

     
   

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