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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 26-50 out of 3762.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>

Public Release: 1-Sep-2015
Cancer Research
Newly engineered CAR T cells can better discriminate between cancer and normal cells
A new development in engineering chimeric antigen receptor (CAR) T cells, called affinity tuning, can make the CAR T cells spare normal cells and better recognize and attack cancer cells, which may help lower the toxicity associated with this type of immunotherapy when used against solid tumors, according to a preclinical study.
National Institutes of Health

Contact: Julia Gunther
American Association for Cancer Research

Public Release: 1-Sep-2015
Neurobiology of Disease
Mass. General study identifies another way urate may protect against Parkinson's disease
A study from members of the research team investigating whether increasing blood levels of the antioxidant urate can slow the progression of Parkinson's disease has found that the neuroprotective effects of urate extend beyond its own antioxidant properties. An NIH-funded phase 3 trial of a urate-elevating drug, led by the senior author of the current study, will begin enrolling patients next year.
US Department of Defense, NIH/National Institute of Neurological Disorders and Stroke

Contact: Terri Ogan
Massachusetts General Hospital

Public Release: 1-Sep-2015
Genetic landscape can impact treatment for children with rare, aggressive cancer
For children with rare, aggressive and advanced cancer, precision medicine may help doctors determine their best treatment options, a new study finds. Using information from a patient's entire genome helped suggest personalized treatment options for nearly half of children with cancer, and led to specific treatment changes in a quarter of these patients.
National Institutes of Health, Prostate Cancer Foundation, Good Charity Inc.

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 31-Aug-2015
Psychiatric Services
Organized self-management support eases chronic depression
In a randomized trial, people with chronic or recurrent depression benefited from self-management support that included regular outreach care management and a self-care group with a combined behavioral and recovery-oriented approach. Over 18 months, patients improved significantly in all four measured outcomes. Compared to patients in usual care at Group Health and Swedish, they had less severe symptoms and less likelihood of having major depression, higher recovery scores, and higher likelihood of being much improved.
NIH/National Institute of Mental Health

Contact: Rebecca Hughes
Group Health Research Institute

Public Release: 31-Aug-2015
Northwestern, partners launch AIDS research center to stop HIV
A new $6.25 million NIH grant will create a Third Coast Coast Center for AIDS Research to help investigators from Northwestern University, the University of Chicago and others across the city of Chicago work together to slow and stop HIV. HIV infections rise 5 percent each year in young gay men.
National Institutes of Health

Contact: Marla Paul
Northwestern University

Public Release: 31-Aug-2015
Research in mice shows potential value of antidepressant in some stroke victims
Working with mice, researchers at Johns Hopkins have added to evidence that a commonly prescribed antidepressant called fluoxetine helps stroke victims improve movement and coordination, and possibly why.
Johns Hopkins, NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of Child Health and Human Development, James S. McDonnell Foundation, National Science Foundation

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 31-Aug-2015
New UC Davis environmental research center links science with advocacy
A cross-disciplinary center focused on identifying connections between environmental toxins and disease has been established at UC Davis Health System with the ultimate goal of developing preventions and policies that protect communities from unhealthy exposures.
NIH/National Institute of Environmental Health Sciences

Contact: Karen Finney
University of California - Davis Health System

Public Release: 31-Aug-2015
Using nanotechnology to fight cancer
Northwestern University, a leader in cancer nanotechnology research, has received a five-year, $11.7 million grant from the National Cancer Institute to use nanotechnology to develop next-generation cancer treatments. The Northwestern University Center for Cancer Nanotechnology Excellence will use nucleic-acid-based nanoconstructs called Spherical Nucleic Acids to access intracellular environments, discover new aspects of cancer biology and create effective cancer treatment options. A focus will be on helping those suffering from glioblastoma multiforme and prostate cancer.
NIH/National Cancer Institute

Contact: Megan Fellman
Northwestern University

Public Release: 31-Aug-2015
$13 million grant to continue funding for new social science research methods
The Methodology Center at Penn State has received a $13 million grant from the National Institute on Drug Abuse to support both ongoing and new research for the next five years that could lead to health apps for smartphones and more accurate genetic research.
NIH/National Institute on Drug Abuse

Contact: Victoria M. Indivero
Penn State

Public Release: 31-Aug-2015
Nature Medicine
Infection with multiple HIV-1 variants leads to poorer clinical outcomes
HIV-1 infection with multiple founder variants points to poorer clinical outcomes than infection with a single variant, according to a paper published today in Nature Medicine. In the study researchers analyzed large sample sets from two important HIV vaccine efficacy trials -- the Step HIV vaccine clinical trial (HVTN 502) and RV144, the landmark vaccine clinical trial conducted in Thailand -- to evaluate whether genetic characteristics of the founder viral populations could influence markers of clinical outcomes.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Lisa Reilly
The U.S. Military HIV Research Program (MHRP)

Public Release: 31-Aug-2015
NCI awards SPORE grant to multiple myeloma research team from Mayo Clinic Cancer Center
A team of Mayo Clinic Cancer Center scientists has been awarded a Specialized Program of Research Excellence (SPORE) grant in multiple myeloma from the National Cancer Institute. The Mayo Clinic Cancer Center is one of only three cancer centers to receive a SPORE grant for multiple myeloma cancer research.
NIH/National Cancer Institute

Contact: Joe Dangor
Mayo Clinic

Public Release: 31-Aug-2015
Nature Methods
DNA-guided 3-D printing of human tissue is unveiled
UCSF researchers developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks. These mini-tissues in a dish can be used to study how particular structural features of tissue affect normal growth or go awry in cancer; for therapeutic drug screening and to help teach researchers how to grow whole human organs.
The Department of Defense Breast Cancer Research Program, the National Institutes of Health, the Sidney Kimmel Foundation, the UCSF Program in Breakthrough Biomedical Research

Contact: Nicholas Weiler
University of California - San Francisco

Public Release: 31-Aug-2015
Biosensors and Bioelectronics
Mouth guard monitors health markers, transmits information wirelessly to smart phone
Engineers at the University of California, San Diego, have developed a mouth guard that can monitor health markers, such as lactate, cortisol and uric acid, in saliva and transmit the information wirelessly to a smart phone, laptop or tablet. The technology, which is at a proof-of-concept stage, could be used to monitor patients continuously without invasive procedures, as well as to monitor athletes' performance or stress levels in soldiers and pilots.
National Institutes of Health, Air Force Research Laboratory

Contact: Liezel Labios
University of California - San Diego

Public Release: 31-Aug-2015
New research confirms lack of sleep connected to getting sick
In 2009, Carnegie Mellon University's Sheldon Cohen found for the first time that insufficient sleep is associated with a greater likelihood of catching a cold. To do this, Cohen assessed participants self-reported sleep duration and efficiency levels and then exposed them to a common cold virus. Now, Cohen and other researchers have confirmed that insufficient sleep is connected to an increased chance of getting sick using objective sleep measures.
NIH/National Center for Complementary and Integrative Health, NIH/National Institute of Allergy and Infectious Diseases, NIH/National Heart, Lung, and Blood Institute, National Institutes of Health

Contact: Shilo Rea
Carnegie Mellon University

Public Release: 31-Aug-2015
Psychological Science
Close friendships in adolescence predict health in adulthood
Teens are often warned to beware the undue influence of peer pressure, but new research suggests that following the pack in adolescence may have some unexpected benefits for physical health in early adulthood.
NIH/National Institute of Child Health and Human Development, NIH/National Institute of Mental Health

Contact: Anna Mikulak
Association for Psychological Science

Public Release: 31-Aug-2015
Nature Medicine
'Eat me' signal whets appetites for tumor-devouring dendritic cells
The therapeutic effect of CD47 blockade as a cancer treatment relies more on dendritic cells than macrophages. Anti-CD47-mediated tumor rejection will require both innate and adaptive responses.
National Institutes of Health, Chinese Academy of Sciences

Contact: John Easton
University of Chicago Medical Center

Public Release: 31-Aug-2015
Journal of Cell Biology
Inducing metabolic catastrophe in cancer cells
Researchers at Harvard Medical School describe a way to force cancer cells to destroy a key metabolic enzyme they need to survive.
Harvard Accelerator Fund, Ludwig Center at Harvard, Chinese Academy of Sciences, Swedish Research Council, Swedish Society for Medical Research, NIH/Bational Heart, Lung, and Blood Institute, and others

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 31-Aug-2015
American Journal of Preventive Medicine
'Happy Meals' bill could improve healthfulness of fast food meals for kids in NYC
A bill to improve the nutritional value of fast food restaurant meals marketed to children -- like McDonald's Happy Meals -- could have a wide enough impact to reduce calories, fat, and sodium, according to a new study led by researchers at NYU Langone Medical Center.
NIH/National Institute of Diabetes and Digestive and Kidney Disorders, New York State Health Foundation, Robert Wood Johnson Foundation

Contact: Allison Clair
NYU Langone Medical Center / New York University School of Medicine

Public Release: 28-Aug-2015
UC San Diego cancer researchers receive NCI Outstanding Investigator Award
Four University of California, San Diego School of Medicine researchers have been selected to receive the newly established National Cancer Institute Outstanding Investigator Award. The multi-million dollar awards fund new projects that have an unusual potential in cancer research over seven years.
NIH/National Cancer Institute

Contact: Yadira Galindo
University of California - San Diego

Public Release: 28-Aug-2015
OU and Mercy Hospital OKC developing new screening models for breast cancer detection
The University of Oklahoma and Mercy Hospital Oklahoma City are developing new short-term breast cancer risk prediction models that aim to help increase cancer detection of breast magnetic resonance imaging screening. With a $2.5 million grant from the National Institutes of Health/National Cancer Institute, OU and Mercy will develop and apply two new short-term breast cancer risk prediction approaches: a rule-in approach and a rule-out approach.
NIH/National Cancer Institute

Contact: Jana Smith
University of Oklahoma

Public Release: 28-Aug-2015
Angewandte Chemie
Researchers use DNA 'clews' to shuttle CRISPR-Cas9 gene-editing tool into cells
Researchers have for the first time created and used a nanoscale vehicle made of DNA to deliver a CRISPR-Cas9 gene-editing tool into cells in both cell culture and an animal model.
National Institutes of Health, National Science Foundation

Contact: Matt Shipman
North Carolina State University

Public Release: 28-Aug-2015
Cancer Prevention Research
Moffitt makes important steps toward developing a blood test to catch pancreatic cancer early
According to a new 'proof of principle' study published in Aug. 27 issue of Cancer Prevention Research, Moffitt Cancer Center researchers hope to improve pancreatic cancer survival rates by identifying markers in the blood that can pinpoint patients with premalignant pancreatic lesions called intraductal papillary mucinous neoplasms.
American Cancer Society, NIH/National Cancer Institute

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 27-Aug-2015
JAMA Neurology
Degenerating neurons respond to gene therapy treatment for Alzheimer's disease
Degenerating neurons in patients with Alzheimer's disease measurably responded to an experimental gene therapy in which nerve growth factor was injected into their brains, report researchers at University of California, San Diego School of Medicine in the current issue of JAMA Neurology.
National Institutes of Health, Veterans Health Administration, Alzheimer's Association, Donald and Darlene Shiley Family Trusts and Ceregene, Inc.

Contact: Scott LaFee
University of California - San Diego

Public Release: 27-Aug-2015
Cell Reports
HIV particles do not cause AIDS, our own immune cells do
Scientists from the Gladstone Institutes have discovered that HIV does not cause AIDS by the virus's direct effect on the host's immune cells, but rather through the cells' lethal influence on one another. In a new Cell Reports study, the researchers revealed that the HIV 'death pathway' -- how 95 percent of cells die from the virus -- is only initiated if the virus is passed from cell-to-cell, not if cells are infected by free-floating viral particles.
National Institutes of Health, NIH/National Institute of Allergy and Infectious Diseases

Contact: Dana Smith
Gladstone Institutes

Public Release: 27-Aug-2015
Pitt team identifies cause of resilience to tinnitus, potential drug therapy
Researchers have identified in an animal model the molecular mechanisms behind resilience to noise-induced tinnitus and a possible drug therapy that could reduce susceptibility to this chronic and sometimes debilitating condition. The findings by a team from the University of Pittsburgh School of Medicine were published online in the journal eLife.
US Department of Defense Peer Reviewed Medical Research Program, Joint Warfighter Medical Research Program, National Institutes of Health

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Showing releases 26-50 out of 3762.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>


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