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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 26-50 out of 3739.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>

Public Release: 28-Jun-2015
Lancet Global Health
More secondary schooling reduces HIV risk
Longer secondary schooling substantially reduces the risk of HIV infection -- especially for girls -- and could be a very cost-effective way to halt the spread of the virus, according to researchers from Harvard T.H. Chan School of Public Health. In a study in Botswana, researchers found that, for each additional year of secondary school, students lowered their risk of HIV infection by 8 percentage points about a decade later, from 25 percent to about 17 percent infected.
Harvard T.H. Chan School of Public Health, Belgian American Educational Foundation, Fernand Lazard Foundation, Boston University, National Institutes of Health

Contact: Marge Dwyer
mhdwyer@hsph.harvard.edu
617-432-8416
Harvard School of Public Health

Public Release: 26-Jun-2015
Stroke
Having a stroke? Where you are makes a huge difference in your treatment
It looks like a crazy quilt spread over the continent. But a new map of emergency stroke care in America shows just how much of a patchwork system we still have for delivering the most effective stroke treatment. And thousands of people a year may end up unnecessarily disabled as a result.
NIH/National Institute for Neurological Disorders and Stroke, NIH/National Institute of Minority Health and Health Disparities

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 26-Jun-2015
PLOS Medicine
High blood pressure linked to reduced Alzheimer's risk, meds may be reason
A new study suggests that people with a genetic predisposition to high blood pressure have a lower risk for Alzheimer's disease. However, authors conclude the connection may have more to do with anti-hypertension medication than high blood pressure itself.
Innovative Medicines Initiative Joint Undertaking, National Institute for Health Research, Maudsley NHS Foundation Trust, National Institutes of Health, NIH/National Institute on Aging

Contact: Todd Hollingshead
toddh@byu.edu
801-422-8373
Brigham Young University

Public Release: 26-Jun-2015
Genes & Development
Braking mechanism identified for cell growth pathway linked to several cancers
Researchers at University of California, San Diego School of Medicine have discovered a self-regulating loop in the Hippo pathway, a signaling channel garnering increased attention from cancer researchers due to its role in controlling organ size, cell proliferation and cell death.
National Institutes of Health, Japan Society for the Promotion of Science, Yasuda Medical Foundation, UC San Diego

Contact: Bonnie Ward
bjward@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 25-Jun-2015
Neurobiology of Aging
Alzheimer's disease works differently in patients with and without Down syndrome
Researchers at the University of Kentucky's Sanders-Brown Center on Aging have completed a study that revealed differences in the way brain inflammation -- considered a key component of Alzheimer's disease -- is expressed in different subsets of patients, in particular people with Down syndrome and AD.
NIH/National Institute of Child Health and Human Development, Alzheimer's Association, Global Down Syndrome Foundation, Linda CRNIC Institute for Down Syndrome

Contact: Laura Dawahare
Laura.Dawahare@uky.edu
859-257-5307
University of Kentucky

Public Release: 25-Jun-2015
Stem Cell Reports
Researchers uncover epigenetic switches that turn stem cells into blood vessel cells
Researchers at the University of Illinois at Chicago have identified a molecular mechanism that directs embryonic stem cells to mature into endothelial cells -- the specialized cells that form blood vessels. Understanding the processes initiated by this mechanism could help scientists more efficiently convert stem cells into endothelial cells for use in tissue repair, or for engineering blood vessels to bypass blockages in the heart.
NIH/National Heart, Lung and Blood Institute

Contact: Sharon Parmet
sparmet@uic.edu
312-413-2695
University of Illinois at Chicago

Public Release: 25-Jun-2015
Journal of Biological Chemistry
A person's diet, acidity of urine may affect susceptibility to UTIs
The acidity of urine -- as well as the presence of small molecules related to diet -- may influence how well bacteria can grow in the urinary tract, a new study shows. The research, at Washington University School of Medicine in St. Louis, may have implications for treating urinary tract infections, which are among the most common bacterial infections worldwide.
National Institutes of Health, Longer Life Foundation, United States Public Health Service, Burroughs Wellcome Fund, Monsanto Excellence Fund Graduate Fellowship, Barnes-Jewish Hospital Patient Safety & Quality Fellowship Program

Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine

Public Release: 25-Jun-2015
Proceedings of the Royal Society B
Tracking the genetic arms race between humans and mosquitoes
Individual populations of mosquitoes are under strong evolutionary pressure from humans and their environment, a new study shows.
National Institutes of Health, Russian Science Ministry

Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California

Public Release: 25-Jun-2015
Journal of Alzheimer's Disease
Multiple pathways progressing to Alzheimer's disease
UC San Diego School of Medicine researchers report that the amyloid cascade hypothesis, long believed to describe the pathology of Alzheimer's disease, is not a fixed and invariable sequence of events. Rather, early indicators or biomarkers of the neurodegenerative condition vary by individual, making preclinical diagnoses more challenging.
National Institutes of Health

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 25-Jun-2015
UNC researchers develop innovative gene transfer-based treatment approach
University of North Carolina School of Medicine researchers have developed an innovative, experimental gene transfer-based treatment for children with giant axonal neuropathy.
Hannah's Hope Fund, NIH/National Institute of Neurological Disorders and Stroke

Contact: Tom Hughes
Tom.Hughes@unchealth.unc.edu
984-974-1151
University of North Carolina Health Care

Public Release: 25-Jun-2015
Developmental Cell
Chloroplast tubes play a key role in plants' immune defense
When plant cells are infected with pathogens, networks of tiny tubes called stromules grow from the chloroplasts to the cell's nucleus and trigger programmed cell death and innate immune responses.
National Institutes of Health

Contact: Andy Fell
ahfell@ucdavis.edu
530-752-4533
University of California - Davis

Public Release: 25-Jun-2015
Chemistry & Biology
New approach holds promise for earlier, easier detection of colorectal cancer
Chemists at Caltech have developed a new sensitive electrochemical technique capable of detecting colorectal cancer in tissue samples -- a method that could one day be used in clinical settings for the early diagnosis of colorectal cancer.
National Institutes of Health

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Public Release: 25-Jun-2015
Acta Crystallographica Section D
The silent partner in macromolecular crystals
On average, the mother liquor or solvent and its constituents occupy about 50 percent of a macromolecular crystal. Ordered as well as disordered solvent components need to be accurately accounted for in modelling and refinement, often with considerable complexity.
Marie Curie People Action Grant, National Institutes of Health, Phoenix Industrial Consortium, US Department of Energy

Contact: Dr. Jonathan Agbenyega
ja@iucr.org
44-124-434-2878
International Union of Crystallography

Public Release: 25-Jun-2015
Journal of the National Cancer Institute
Development of new blood vessels not essential to growth of lymph node metastases
A Massachusetts General Hospital Cancer Center research team reports has found that the growth of metastases in lymph nodes -- the most common site of cancer spread -- does not require the development of new blood vessels, potentially explaining why antiangiogenesis drugs have failed to prevent the development of new metastases.
National Institutes of Health, National Cancer Institute

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Public Release: 25-Jun-2015
Cell Host & Microbe
New target identified for inhibiting malaria parasite invasion
A new study led by researchers at Harvard T.H. Chan School of Public Health finds that a malaria parasite protein called calcineurin is essential for parasite invasion into red blood cells.
National Institutes of Health, American Cancer Society

Contact: Todd Datz
tdatz@hsph.harvard.edu
617-432-8413
Harvard School of Public Health

Public Release: 25-Jun-2015
Cell Reports
TSRI team gets new close-up view of key part of Ebola virus life cycle
A new study led by scientists at the Scripps Research Institute reveals a key part of the Ebola virus life cycle at a higher resolution than ever before. The research sheds light on how Ebola virus assembles -- and how researchers might stop the often-fatal infection.
Skaggs Institute of Chemical Biology, Burroughs Wellcome Fund, National Institutes of Health, NIH/National Cancer Institute, NIH/National Institute of General Medical Sciences, Advanced Photon Source

Contact: Madeline McCurry-Schmidt
madms@scripps.edu
858-784-9254
Scripps Research Institute

Public Release: 25-Jun-2015
Brain
Redrawing language map of brain
For 140 years, scientists' understanding of language comprehension in the brain came from individuals with stroke. But now they have redrawn that brain map based on new research with individuals who have a rare form of dementia that affects language, primary progressive aphasia. Northwestern scientists discovered language comprehension is in a different neighborhood, providing a more precise brain target for future therapies to restore language.
National Institutes of Health

Contact: Marla Paul
marla-paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 25-Jun-2015
Cell Reports
Wistar scientists pinpoint mutations responsible for ineffective 2014-2015 flu vaccine
Viruses like influenza have the ability to mutate over time, and given that the flu vaccines administered during the 2014-2015 season were largely ineffective at preventing the spread of the flu, it appears the virus that recently circulated had taken on mutations not accounted for when last year's vaccine was developed. Now, researchers at The Wistar Institute identified specific mutations that influenza recently acquired to escape the current vaccine design.
National Institutes of Health

Contact: Ben Leach
bleach@wistar.org
215-495-6800
The Wistar Institute

Public Release: 25-Jun-2015
Neuron
What controls blood flow in the brain?
In a paper published on June 25 in Neuron, Yale University scientists present the strongest evidence yet that smooth muscle cells surrounding blood vessels in the brain are the only cells capable of contracting to control blood vessel diameter and thus regulate blood flow. This basic anatomical understanding may also have important implications for phenomena observed in stroke and migraines.
National Institutes of Health

Contact: Joseph Caputo
jcaputo@cell.com
617-335-6270
Cell Press

Public Release: 25-Jun-2015
Science
Penn researchers identify stem-like progenitor cell that exclusively forms heart muscle
Future therapies for failing hearts are likely to include stem-like cells and associated growth factors that regenerate heart muscle. Scientists have just taken an important step towards that future by identifying a stem-like 'progenitor' cell that produces only heart muscle cells.
NIH/National Heart, Lung, and Blood Institute, Cotswold Foundation, Spain Fund for Regenerative Cardiology

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-459-0544
University of Pennsylvania School of Medicine

Public Release: 25-Jun-2015
Cell Reports
Calcium uptake by mitochondria makes heart beat harder in fight-or-flight response
In a life-threatening situation, the heart beats faster and harder, invigorated by the fight-or-flight response, which instantaneously prepares a person to react or run. Now, a new study by researchers at Temple University School of Medicine shows that the uptick in heart muscle contractility that occurs under acute stress is driven by a flood of calcium into mitochondria -- the cells' energy-producing powerhouses.
NIH/National Heart, Lung, and Blood Institute, American Heart Association

Contact: Jeremy Walter
Jeremy.Walter@tuhs.temple.edu
267-838-0398
Temple University Health System

Public Release: 25-Jun-2015
PLOS Computational Biology
Computer simulation predicts development, progress of pressure sores
Researchers at the University of Pittsburgh School of Medicine have devised a computational model that could enhance understanding, diagnosis and treatment of pressure ulcers related to spinal cord injury. In a report published online in PLOS Computational Biology, the team also described results of virtual clinical trials that showed that for effective treatment of the lesions, anti-inflammatory measures had to be applied well before the earliest clinical signs of ulcer formation.
US Department of Education, NIH/National Institute on Disability and Rehabilitation Research, IBM Shared University Research Award

Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences

Public Release: 24-Jun-2015
Diabetes
Johns Hopkins scientists restore normal function in heart muscle cells of diabetic rats
Working with heart muscle cells from diabetic rats, scientists at Johns Hopkins have located what they say is the epicenter of mischief wreaked by too much blood sugar and used a sugar-gobbling enzyme to restore normal function in the glucose-damaged cells of animal heart muscles.
NIH/National Heart, Lung, and Blood Institute, American Heart Association's Lawrence and Florence A. DeGeorge Charitable Trust Scientist Developing, NIH/National Institute of General Medical Sciences

Contact: Ekaterina Pesheva
epeshev1@jhmi.edu
410-502-9433
Johns Hopkins Medicine

Public Release: 24-Jun-2015
Cancer Prevention Research
Weight loss plus vitamin D reduces inflammation linked to cancer, chronic disease
For the first time, researchers at Fred Hutchinson Cancer Research Center have found that weight loss, in combination with vitamin D supplementation, has a greater effect on reducing chronic inflammation than weight loss alone. Chronic inflammation is known to contribute to the development and progression of several diseases, including some cancers.
Breast Cancer Research Foundation, Susan G. Komen for the Cure, National Institutes of Health, Seattle Cancer Consortium Breast Cancer Specialized Program in Research Excellence, Fred Hutchinson/University of Washington Cancer Consortium, and others

Contact: Kristen Woodward
kwoodwar@fredhutch.org
206-667-5095
Fred Hutchinson Cancer Research Center

Public Release: 24-Jun-2015
Chest
Cystic fibrosis deadlier for Hispanic than non-Hispanic patients, Stanford study finds
Cystic fibrosis is more deadly for Hispanic than non-Hispanic patients, a disparity that is not explained by differences in their access to health care, according to a new study from the Stanford University School of Medicine.
Cystic Fibrosis Foundation, Ernest and Amelia Gallo Endowed Postdoctoral Fellowship, Lucile Packard Foundation for Children's Health, National Institutes of Health, and others

Contact: Erin Digitale
digitale@stanford.edu
650-724-9175
Stanford University Medical Center

Showing releases 26-50 out of 3739.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>

     
   

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