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Showing releases 26-50 out of 3154. << < 1 | 2 | 3 | 4 | 5 | 6 > >>

Public Release: 29-Nov-2012
 Science
Harvard's Wyss Institute team creates versatile 3d nanostructures using DNA 'bricks'
Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have created more than 100 three-dimensional nanostructures using DNA building blocks that function like Lego bricks -- a major advance from the two-dimensional structures the same team built a few months ago.

Office of Naval Research, Army Research Office, National Science Foundation, National Institutes of Health, Harvard/Wyss Institute
Contact: Kristen Kusek
kristen.kusek@wyss.harvard.edu
617-432-8266
Wyss Institute for Biologically Inspired Engineering at Harvard
Public Release: 29-Nov-2012
 Science
Molecular root of 'exhausted' T cells in chronic viral infection
In the case of such pathogens as hepatitis C, HIV, and malaria, the body and the pathogen essentially fight to a prolonged stalemate, neither able to gain an advantage. Over time, however, the cells become "exhausted" and the immune system can collapse, giving the pathogen the edge. A new study is showing how that happens, suggesting a novel approach that might shift the balance of power in chronic infections.

National Institutes of Health, Dana Foundation
Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Public Release: 28-Nov-2012
 Nature
Most of the harmful mutations in people arose in the past 5,000 to 10,000 years
A study of the age of more than 1 million single-letter variations in the human DNA code reveals that most of these mutations are of recent origin, evolutionarily speaking. They arose as a result of explosive population growth, which provides more chances for new mutations to appear in offspring. Many of these mutations are harmful, some have no effect, and others are beneficial now or may provide an adaptive advantage for future generations.

NIH/National Heart, Lung, and Blood Institute Exome Sequencing Project
Contact: Leila Gray
leilag@uw.edu
206-685-0381
University of Washington
Public Release: 28-Nov-2012
 Nature
Rules devised for building ideal protein molecules from scratch
By following certain rules, scientists can prepare architectural plans for building ideal protein molecules not found in the real world. Based on computer renditions, previously non-existent proteins can be produced from scratch in the lab. In our imperfect world, proteins can be beset by bulges, kinks, strains, and improperly buried parts, and many diseases arise from protein malformations. The researchers achieved a library of several ideal structures. The principles could aid in designing drugs, vaccines, industrial enzymes, fuels, and pollutant removers.

Defense Advanced Research Projects Agency, Department of Energy, Defense Threat Reduction Agency, National Institutes of Health, Howard Hughes Medical Institute, Japan Society for Promotion of Science
Contact: Leila Gray
leilag@uw.edu
206-685-0381
University of Washington
Public Release: 28-Nov-2012
 Environmental Science & Technology
Study IDs kerosene lamps as big source of black carbon
Kerosene lamps, the primary source of light for more than a billion people in developing nations, churns out black carbon at levels previously overlooked in greenhouse gas estimates, according to a new study led by researchers at UC Berkeley and the University of Illinois. The new findings result in a twentyfold increase to previous estimates of black carbon emissions from kerosene-fueled lighting. The good news is that affordable, cleaner alternatives exist.

US Centers for Disease Control and Prevention, NIH/National Institute of Environmental Health Sciences, US Agency for International Development, US Environmental Protection Agency
Contact: Sarah Yang
scyang@berkeley.edu
510-643-7741
University of California - Berkeley
Public Release: 28-Nov-2012
 Environmental Research
Women 16-49 at risk of multiple pollutants
In a new analysis of thousands of US women of childbearing age, Brown University researchers found that most exceeded the median blood level for two or more of three environmental pollutants that could harm brain development of fetuses and babies: lead, mercury, and polychlorinated biphenyls.

NIH/National Institute of Environmental Health Sciences, University of Rhode Island, Sigma Theta Tau
Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Public Release: 28-Nov-2012
 Proceedings of the National Academy of Sciences
Double duty: Immune system regulator found to protect brain from effects of stroke
A small molecule known to regulate white blood cells has a surprising second role in protecting brain cells from the deleterious effects of stroke, Johns Hopkins researchers report. The molecule, microRNA-223, affects how cells respond to the temporary loss of blood supply brought on by stroke -- and thus the cells' likelihood of suffering permanent damage.

NIH/National Institute on Drug Abuse, Maryland Stem Cell Research Fund
Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine
Public Release: 28-Nov-2012
 Journal of Lipid Research
Analysis of conflicting fish oil studies finds that omega-3 fatty acids still matter
A new analysis helps to sort through conflicting findings from literally hundreds of studies on use of omega-3 fatty acids for heart disease. It concludes that they still matter; they do work; and that modern therapies for cardiovascular disease help to mask the benefits omega-3 consumption might otherwise provide.

US Department of Agriculture, National Institutes of Health
Contact: Donald Jump
Donald.Jump@oregonstate.edu
541-737-4007
Oregon State University
Public Release: 28-Nov-2012
 Journal of Biological Chemistry
Scripps Florida scientists uncover a novel cooperative effort to stop cancer spread
Scientists from the Florida campus of The Scripps Research Institute have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the spread of cancer from its primary site.

National Institutes of Health
Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute
Public Release: 28-Nov-2012
 Science Translational Medicine
Johns Hopkins scientists pair blood test and gene sequencing to detect cancer
Scientists at the Johns Hopkins Kimmel Cancer Center have combined the ability to detect cancer DNA in the blood with genome sequencing technology in a test that could be used to screen for cancers, monitor cancer patients for recurrence and find residual cancer left after surgery.

National Institutes of Health
Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine
Public Release: 28-Nov-2012
Potentially toxic flame retardants found in many US couches
More than half of all couches tested in a Duke University-led study contained potentially toxic or untested chemical flame retardants that may pose risks to human health.

NIH/National Institute of Environmental Health Sciences
Contact: Tim Lucas
tdlucas@duke.edu
919-613-8084
Duke University
Public Release: 28-Nov-2012
 Nature
Chemists invent powerful toolkit, accelerating creation of potential new drugs
Scientists at The Scripps Research Institute have invented a set of chemical tools that is radically simplifying the creation of potential new drug compounds.

National Institutes of Health, Pfizer
Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute
Public Release: 28-Nov-2012
 Environmental Science and Technology
New study: Many flame retardants in house dust -- unsafe levels
In Silent Spring Institute's new peer-reviewed study of the largest number of flame retardants ever tested in homes, we found that most houses had levels of at least one flame retardant that exceeded a federal health guideline.

NIH/National Institute of Environmental Health Sciences, New York Community Trust, Fine Fund, Art beCAUS
Contact: Kathryn Rodgers
rodgers@silentspring.org
617-332-4288 x225
Silent Spring Institute
Public Release: 27-Nov-2012
 Blood
Scripps Research Institute study points to potential new therapies for cancer and other diseases
Researchers at the Scripps Research Institute are fueling the future of cancer treatment by improving a powerful tool in disease defense: the body's immune system. By revealing a novel but widespread cell signaling process, the scientists may have found a way to manipulate an important component of the immune system into more effectively fighting disease.

National Institutes of Health, Leukemia and Lymphoma Society, Deutsche Forschungsgemeinschaft
Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute
Public Release: 27-Nov-2012
 Journal of Adolescent Health
Reducing sibling rivalry in youth improves later health and well-being
Sibling conflict represents parents' No. 1 concern and complaint about family life, but a new prevention program -- designed and carried out by researchers at Penn State -- demonstrates that siblings of elementary-school age can learn to get along. In doing so, they can improve their future health and well-being.

NIH/National Institute of Drug Abuse, Penn State Children, Youth, and Family Consortium
Contact: Sara LaJeunesse
SDL13@psu.edu
814-863-4325
Penn State
Public Release: 27-Nov-2012
 Nature Cell Biology
What keeps a cell's energy source going
Most healthy cells rely on a complicated process to produce the fuel ATP. Knowing how ATP is produced by the cell's energy storehouse -- the mitochondria -- is important for understanding a cell's normal state, as well as what happens when things go wrong, for example in cancer, cardiovascular disease, neurodegeneration, and many rare disorders of the mitochondria.

NIH/National Heart, Lung, and Blood Institute, NIH/National Institute of General Medical Sciences, American Heart Association
Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Public Release: 27-Nov-2012
 Investigative Ophthalmology & Visual Science
Compound found in rosemary protects against macular degeneration in laboratory model
Researchers at Sanford-Burnham Medical Research Institute report that carnosic acid, a component of the herb rosemary, promotes eye health. The team found that carnosic acid protects retinas from degeneration and toxicity in cell culture and in rodent models of light-induced retinal damage. Their findings, published in the journal Investigative Ophthalmology & Visual Science, suggest that carnosic acid may have clinical applications for diseases affecting the outer retina, including age-related macular degeneration.

National Institutes of Health
Contact: Heather Buschman, Ph.D.
hbuschman@sanfordburnham.org
858-795-5343
Sanford-Burnham Medical Research Institute
Public Release: 27-Nov-2012
 Pediatrics
Gene linked to respiratory distress in babies
Some infants are more susceptible to potentially life-threatening breathing problems after birth, and rare, inherited DNA differences may explain why, according to research at Washington University School of Medicine in St. Louis.

National Institutes of Health, Eudowood Foundation, Children's Discovery Institute and others
Contact: Elizabethe Holland Durando
elizabethe.durando@wustl.edu
314-286-0119
Washington University School of Medicine
Public Release: 27-Nov-2012
 Vaccine
Measles vaccine given with a microneedle patch could boost immunization programs
Measles vaccine given with painless and easy-to-administer microneedle patches can immunize against measles at least as well as vaccine given with conventional hypodermic needles, according to research done by the Georgia Institute of Technology and the Centers for Disease Control and Prevention.

Centers for Disease Control and Prevention, National Institutes of Health
Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology Research News
Public Release: 27-Nov-2012
 Proceedings of the National Academy of Sciences
Flu outbreaks predicted with weather forecast techniques
Scientists have developed a new system that adapts techniques used in weather prediction to generate local forecasts of seasonal influenza outbreaks. By predicting the timing and severity of the outbreaks as far as seven weeks in advance, the system can eventually help society better prepare for them.

National Institutes of Health, Department of Homeland Security, National Science Foundation
Contact: David Hosansky
hosansky@ucar.edu
303-497-8611
National Center for Atmospheric Research/University Corporation for Atmospheric Research
Public Release: 27-Nov-2012
 Nature Structural & Molecular Biology
New mechanism for cancer progression discovered by UNC and Harvard researchers
University of North Carolina Lineberger Comprehensive Cancer Center and Harvard researchers have discovered an alternative mechanism for activating rhe oncogene Ras that does not require mutation or hormonal stimulus.

National Institutes of Health, Japanese Society for the Promotion of Science Research, Kanae Foundation for Research Abroad
Contact: William Davis
william_davis@med.unc.edu
919-962-3405
University of North Carolina Health Care
Public Release: 27-Nov-2012
 Proceedings of the National Academy of Sciences
Protein injection points to muscular dystrophy treatment
Scientists have discovered that injecting a novel human protein into muscle affected by Duchenne muscular dystrophy significantly increases its size and strength, findings that could lead to a therapy akin to the use of insulin by diabetics. These results were published today in the Proceedings of the National Academy of Sciences by Dr. Julia von Maltzahn and Dr. Michael Rudnicki, the Ottawa scientist who discovered muscle stem cells in adults.

Muscular Dystrophy Association, Canadian Institutes of Health Research, National Institutes of Health, Howard Hughes Medical Institute
Contact: Paddy Moore
padmoore@ohri.ca
613-737-8899 x73687
Ottawa Hospital Research Institute
Public Release: 27-Nov-2012

American Society of Clinical Oncology's Quality Care Symposium
Most women who have double mastectomy don't need it, U-M study finds
About 70 percent of women who have both breasts removed following a breast cancer diagnosis do so despite a very low risk of facing cancer in the healthy breast, new research from the University of Michigan Comprehensive Cancer Center finds.

NIH/National Cancer Institute
Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System
Public Release: 27-Nov-2012
 Journal of Clinical Psychiatry
4 common antipsychotic drugs found to lack safety and effectiveness in older adults
In older adults, antipsychotic drugs are commonly prescribed off-label for a number of disorders outside of their Food and Drug Administration-approved indications -- schizophrenia and bipolar disorder. The largest number of antipsychotic prescriptions in older adults is for behavioral disturbances associated with dementia, some of which carry FDA warnings on prescription information for these drugs.

National Institutes of Health, US Department of Veteran Affairs
Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego
Public Release: 26-Nov-2012
 Journal of General Internal Medicine
New behavioral strategies may help patients learn to better control chronic diseases
Physicians should take a serious look at tools and strategies used in behavioral economics and social psychology to help motivate their patients to assert better control over chronic diseases. Breaking large goals into smaller, more manageable parts, for example, may help patients better manage diseases such as diabetes.

National Institutes of Health, University of California, Los Angeles/Drew Project EXPORT, and others
Contact: Enrique Rivero
erivero@mednet.ucla.edu
310-794-2273
University of California - Los Angeles Health Sciences

Showing releases 26-50 out of 3154. << < 1 | 2 | 3 | 4 | 5 | 6 > >>

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