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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 26-50 out of 3483.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>

Public Release: 14-Sep-2014
Nature
How an ancient vertebrate uses familiar tools to build a strange-looking head
In this study, investigator and scientific director Robb Krumlauf, Ph.D., and colleagues show that the sea lamprey Petromyzon marinus, a survivor of ancient jawless vertebrates, exhibits a pattern of gene expression that is reminiscent of its jawed cousins, who evolved much, much later.
Stowers Institute, National Institutes of Health

Contact: Kim Bland, Ph.D.
ksb@stowers.org
816-392-8428
Stowers Institute for Medical Research

Public Release: 14-Sep-2014
Nature Neuroscience
Researchers find neural compensation in people with Alzheimer's-related protein
UC Berkeley researchers have found that the human brain is capable of a neural workaround that compensates for the buildup of beta-amyloid, a destructive protein associated with Alzheimer's disease. The findings could help explain how some older adults with beta-amyloid deposits in their brain retain normal cognitive function while others develop dementia.
NIH/National Institute on Aging, McKnight Foundation

Contact: Sarah Yang
scyang@berkeley.edu
510-643-7741
University of California - Berkeley

Public Release: 14-Sep-2014
Nature Medicine
Muscular dystrophy: Repair the muscles, not the genetic defect
A potential way to treat muscular dystrophy directly targets muscle repair instead of the underlying genetic defect that usually leads to the disease.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH/National Institute of Neurological Disorders and Stroke

Contact: Laura Bailey
baileylm@umich.edu
734-647-1848
University of Michigan

Public Release: 14-Sep-2014
Nature
Nature: New drug blocks gene driving cancer growth
When active, the protein called Ral can drive tumor growth and metastasis in several human cancers including pancreatic, prostate, lung, colon and bladder. Unfortunately, drugs that block its activity are not available. A study published today in the journal Nature uses a novel approach to target the activation of these Ral proteins.
National Institutes of Health

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 12-Sep-2014
Cell Reports
Zebrafish model of a learning and memory disorder shows better treatment
Using a zebrafish model of a human genetic disease called neurofibromatosis, a team from the Perelman School of Medicine at the University of Pennsylvania has found that the learning and memory components of the disorder are distinct features that will likely need different treatment approaches.
NIH/National Heart, Lung and Blood, NIH/Institute National Institute of Mental Health, Department of Defense, FRAXA Research Foundation

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 12-Sep-2014
Journal of Bone and Mineral Research
USC researchers discover the healing power of 'rib-tickling'
Unlike salamanders, mammals can't regenerate lost limbs, but they can repair large sections of their ribs. In a new study in the Journal of Bone and Mineral Research, a team directed by USC Stem Cell researcher Francesca Mariani takes a closer look at rib regeneration in both humans and mice.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Cristy Lytal
lytal@med.usc.edu
323-442-2172
University of Southern California - Health Sciences

Public Release: 12-Sep-2014
Proceedings of the National Academy of Sciences
New glaucoma culprit is found
In a unique study of human ocular cells, a multi-institution team led by a Northwestern University biomedical engineer has found that endothelial cells in Schlemm's canal -- important for draining fluid from the eye -- are stiffer in eyes with glaucoma than those in healthy eyes. The resulting increased flow resistance is responsible for the elevated pressure associated with glaucoma. Therapeutic strategies that alter the stiffness of these cells could lead to a cure for this debilitating disease.
National Institutes of Health, Bright Focus Foundation

Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University

Public Release: 12-Sep-2014
Journal of Clinical Sleep Medicine
Sleep disorders widely undiagnosed in individuals with multiple sclerosis
In what may be the largest study of sleep problems among individuals with multiple sclerosis, researchers at UC Davis have found that widely undiagnosed sleep disorders may be at the root of the most common and disabling symptom of the disease: fatigue.
NIH/National Center for Advancing Translational Sciences, National Institutes of Health

Contact: Phyllis Brown
phyllis.brown@ucdmc.ucdavis.edu
916-734-9023
University of California - Davis Health System

Public Release: 11-Sep-2014
Journal of Neuroscience
Brain inflammation dramatically disrupts memory retrieval networks, UCI study finds
Brain inflammation can rapidly disrupt our ability to retrieve complex memories of similar but distinct experiences, according to UC Irvine neuroscientists Jennifer Czerniawski and John Guzowski.
National Institutes of Health

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine

Public Release: 11-Sep-2014
JAMA Psychiatry
Scientists show that nicotine withdrawal reduces response to rewards across species
While more than half of US smokers try to quit every year, less than 10 percent are able to remain smoke-free, and relapse commonly occurs within 48 hours of smoking cessation. In a first of its kind study on nicotine addiction, scientists measured a behavior that can be similarly quantified across species like humans and rats, the responses to rewards during nicotine withdrawal. Learning about withdrawal and difficulty of quitting can lead to more effective treatments to help smokers quit.
National Institutes of Health

Contact: Gisele Galoustian
ggaloust@fau.edu
561-297-2676
Florida Atlantic University

Public Release: 11-Sep-2014
Cell
Tipping the balance of behavior
Caltech researchers have discovered antagonistic neuron populations in the mouse amygdala that control whether the animal engages in social behaviors or asocial repetitive self-grooming. Dubbed a 'seesaw circuit,' this discovery may have implications for understanding neural circuit dysfunctions that underlie autism in humans.
National Institutes of Health, Simons Foundation, Howard Hughes Medical Institute

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Public Release: 11-Sep-2014
Journal of Clinical Oncology
Penn medicine study reveals profile of patients most likely to delay hospice enrollment
One in six cancer patients enroll in hospice only during their last three days of life, according to a new study from a team from the Perelman School of Medicine at the University of Pennsylvania. Their findings, published online last month in the Journal of Clinical Oncology also reveal a profile of patients who may be most at risk of these late admissions.
National Institutes of Health, Agency for Healthcare Research and Quality

Contact: Greg Richter
gregory.richter@uphs.upenn.edu
215-614-1937
University of Pennsylvania School of Medicine

Public Release: 11-Sep-2014
SpringerPlus
African American women receive less breast reconstruction after mastectomy
Dartmouth researchers have found that African American women are 55 percent less likely to receive breast reconstruction after mastectomy regardless of where they received their care
National Institutes of Health, NIH/National Cancer Institute, American Cancer Society

Contact: Robin Dutcher
robin.Dutcher@hitchcock.org
603-653-9056
The Geisel School of Medicine at Dartmouth

Public Release: 11-Sep-2014
British Journal of Cancer
Dartmouth research links genetic mutation and melanoma progression
Dartmouth researchers have found that the genetic mutation BRAFV600E, frequently found in metastatic melanoma, not only secretes a protein that promotes the growth of melanoma tumor cells, but can also modify the network of normal cells around the tumor to support the disease's progression. Targeting this mutation with Vemurafenib reduces this interaction, and suggests possible new treatment options for melanoma therapy.
National Institutes of Health, Norris Cotton Cancer Center Pilot Grant, Ruth L. Kirschstein National Research Service Award

Contact: Robin Dutcher
603-653-9056
The Geisel School of Medicine at Dartmouth

Public Release: 11-Sep-2014
Inflammatory Bowel Diseases
Proactive monitoring of inflammatory bowel disease therapy could prolong effectiveness
Proactive monitoring and dose adjustment of infliximab, a medication commonly used to treat inflammatory bowel disease, could improve a patient's chances of having a long-term successful response to therapy, a pilot observational study at Beth Israel Deaconess Medical Center concludes.
National Institutes of Health

Contact: Jerry Berger
jberger@bidmc.harvard.edu
617-667-7308
Beth Israel Deaconess Medical Center

Public Release: 11-Sep-2014
American Journal of Hypertension
Study finds high protein diets lead to lower blood pressure
Adults who consume a high-protein diet may be at a lower risk for developing high blood pressure. The study, published in the American Journal of Hypertension, by researchers from Boston University School of Medicine, found participants consuming the highest amount of protein -- an average of 100 g protein/day -- had a 40 percent lower risk of having high blood pressure compared to the lowest intake level.
NIH/National Heart, Lung, and Blood Institute, Boston University School of Medicine, USDA/American Egg Board

Contact: Gina DiGravio
gina.digravio@bmc.oeg
617-638-8480
Boston University Medical Center

Public Release: 11-Sep-2014
Nova Southeastern University researcher receives a nearly $2 million grant
Mary Ann Fletcher, Ph.D., Schemel Professor for Neuro-Immune Medicine at NSU's College of Osteopathic Medicine, and her research team recently were awarded a $1.95 million grant from the National Institutes of Health National Institute of Neurological Disorders and Stroke to study complex biomarkers of CFS/ME in men.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Jeremy Katzman, M.B.A., APR
j.katzman@nova.edu
954-661-7000
Nova Southeastern University

Public Release: 11-Sep-2014
Journal of General Physiology
How bacteria battle fluoride
Two studies from Christopher Miller's lab at Brandeis University provide new insights into the mechanisms that allow bacteria to resist fluoride toxicity, information that could eventually help inform new strategies for treating harmful bacterial diseases.
National Institutes of Health

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Public Release: 11-Sep-2014
Cell Reports
Compound protects brain cells after traumatic brain injury
A new class of compounds, given orally, protects brain cells from the damage caused by blast-induced traumatic brain injury and preserves normal brain functions, even when the compound is given 24 to 36 hours after the injury occurs. The researchers hope that this family of compounds might be developed into a new class of neuroprotective drugs for TBI and other currently untreatable forms of neurodegeneration, including Alzheimer's disease and ALS.
National Institutes of Health, US Department of Veterans Affairs, Veterans Health Administration, National Science Foundation

Contact: Jennifer Brown
jennifer-l-brown@uiowa.edu
319-356-7124
University of Iowa Health Care

Public Release: 11-Sep-2014
American Journal of Public Health
Puerto Ricans who inject drugs among Latinos at highest risk of contracting HIV
The study published in the American Journal of Public Health describes the epidemic and the availability of HIV prevention and treatment programs in areas with a high concentration of Puerto Ricans, in order to provide recommendations to reduce HIV in the population.
NIH/National Institute on Drug Abuse

Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University

Public Release: 11-Sep-2014
Stem Cell Reports
Scientists discover neurochemical imbalance in schizophrenia
Using human induced pluripotent stem cells, researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California, San Diego have discovered that neurons from patients with schizophrenia secrete higher amounts of 3 neurotransmitters broadly implicated in a range of psychiatric disorders.
UC San Diego Academic Senate, Brain and Behavior Research Foundation, National Institutes of Health, JPB Foundation, Leona M. and Harry B. Helmsley Charitable Trust, New York Stem Cell Foundation

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 11-Sep-2014
Cell
Cells put off protein production during times of stress
Duke researchers in North Carolina and Singapore have found that when a stressed cell recognizes the buildup of misfolded proteins, it responds by reshuffling its workload, much like a stressed out employee might temporarily move papers from an overflowing inbox into a junk drawer. The study, which appears Sept. 11, 2014, in Cell, could lend insight into misfolded protein diseases such as Alzheimer's, ALS, Huntington's, Parkinson's, and type 2 diabetes.
National Institutes of Health, Singapore Ministry of Health

Contact: Karl Bates
karl.bates@duke.edu
919-681-8054
Duke University

Public Release: 11-Sep-2014
Cell
Our microbes are a rich source of drugs, UCSF researchers discover
Bacteria that normally live in and upon us have genetic blueprints that enable them to make thousands of molecules that act like drugs, and some of these molecules might serve as the basis for new human therapeutics, according to UC San Francisco researchers.
National Institutes of Health, Defense Advanced Research Projects Agency, W.M. Keck Foundation, David and Lucile Packard Foundation, UCSF Program for Breakthrough Biomedical Research

Contact: Jeffrey Norris
jeffrey.norris@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 11-Sep-2014
Immunity
Intestinal bacteria needed for strong flu vaccine responses in mice
Mice treated with antibiotics to remove most of their intestinal bacteria or raised under sterile conditions have impaired antibody responses to seasonal influenza vaccination, researchers have found. The findings suggest that antibiotic treatment before or during vaccination may impair responses to certain vaccines in humans. The results may also help to explain why immunity induced by some vaccines varies in different parts of the world.
NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Quinn Eastman
qeastm@emory.edu
404-727-7829
Emory Health Sciences

Public Release: 10-Sep-2014
Nature
Sequencing and analysis of gibbon genome sheds light on its complex evolution
A team led by an Oregon Health & Science University researcher has sequenced and annotated the genome of the only ape whose DNA had yet to be sequenced -- the gibbon, an endangered small ape that inhabits the tropical forests of Southeast Asia.
NIH/National Human Genome Research Institute, National Institutes of Health, National Science Foundation, Howard Hughes Medical Institute, European Research Council

Contact: Todd Murphy
murphyt@ohsu.edu
503-494-8231
Oregon Health & Science University

Showing releases 26-50 out of 3483.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>

     
   

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