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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 26-50 out of 3459.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>

Public Release: 27-Aug-2014
Circulation
Protein in 'good cholesterol' may be a key to treating pulmonary hypertension
A new study at UCLA demonstrates that oxidized lipids may contribute to pulmonary hypertension. Using a rodent model, the researchers showed that a peptide mimicking part of the main protein in HDL cholesterol, may help reduce the production of oxidized lipids in pulmonary hypertension. They also found that reducing the amount of oxidized lipids improved the rodents' heart and lung function.
American Heart Association, National Institutes of Health, UCLA Clinical and Translational Science Institute, Iris Cantor-UCLA Women's Health Center

Contact: Rachel Champeau
rchampeau@mednet.ucla.edu
310-794-2270
University of California - Los Angeles Health Sciences

Public Release: 27-Aug-2014
Brain Imaging and Behavior
Kessler Foundation researchers publish first study of brain activation in MS using fNIRS
Using functional near infrared spectroscopy, Kessler Foundation researchers showed differential brain activation patterns between people with multiple sclerosis (MS) and healthy controls. This is first MS study to examine brain activation using fNIRS during a cognitive task. 'Neuroimaging and cognition using functional near infrared spectroscopy (fNIRS) in multiple sclerosis' published online June 11 by Brain Imaging and Behavior.
National MS Society, National Institutes of Health, Kessler Foundation

Contact: Carolann Murphy
CMurphy@KesslerFoundation.org
973-324-8382
Kessler Foundation

Public Release: 27-Aug-2014
Nature
Encyclopedia of how genomes function gets much bigger
A big step in understanding the mysteries of the human genome was unveiled today in the form of three analyses that provide the most detailed comparison yet of how the genomes of the fruit fly, roundworm, and human function. The analyses will likely offer insights into how the information in the human genome regulates development, and how it is responsible for diseases.
NIH/National Human Genome Research Institute

Contact: Dan Krotz
dakrotz@lbl.gov
510-486-4019
DOE/Lawrence Berkeley National Laboratory

Public Release: 27-Aug-2014
Drug Metabolism and Disposition
Dosage of HIV drug may be ineffective for half of African-Americans
Many African-Americans may not be getting effective doses of the HIV drug maraviroc. The initial dosing studies included mostly European-Americans, who generally lack a protein that is key to removing maraviroc from the body, resulting in higher concentrations of the drug in the blood. The current study shows that people with maximum levels of the protein CYP3A5 -- including nearly half of African-Americans -- end up with lower levels of maraviroc in their bodies.
Johns Hopkins Institute for Clinical and Translational Research, NIH/National Center for Research Resources, Pendleton Foundation Trust

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Public Release: 27-Aug-2014
Biological Psychiatry
Scripps Research Institute scientists link alcohol-dependence gene to neurotransmitter
Scientists at The Scripps Research Institute have solved the mystery of why a specific signaling pathway can be associated with alcohol dependence. This signaling pathway is regulated by a gene, called neurofibromatosis type 1 (Nf1), which TSRI scientists found is linked with excessive drinking in mice. The new research shows Nf1 regulates gamma-aminobutyric acid, a neurotransmitter that lowers anxiety and increases feelings of relaxation.
National Institutes of Health, Pearson Center for Alcoholism and Addiction Research, NIH/Genes, Environment and Health Initiative, NIH/National Institute on Alcohol Abuse and Alcoholism, NIH/National Institute on Drug Abuse

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 27-Aug-2014
Nature
Stop and listen: Study shows how movement affects hearing
When we want to listen carefully to someone, the first thing we do is stop talking. The second thing we do is stop moving altogether. The interplay between movement and hearing has a counterpart deep in the brain. A new Duke study, published in Nature, used optogenetics to reveal exactly how the motor cortex, which controls movement, can tweak the volume control in the auditory cortex, which interprets sound.
Helen Hay Whitney Foundation, Holland-Trice Graduate Fellowship in Brain Sciences, National Institutes of Health

Contact: Karl Bates
karl.bates@duke.edu
919-681-8054
Duke University

Public Release: 27-Aug-2014
Infancy: The Official Journal of the International Society on Infant Studies
Parents, listen next time your baby babbles
Parents who try to understand their baby's babbling let their infants know they can communicate, which leads to children forming complex sounds and using language more quickly. Results appear in the journal Infancy.
NIH/National Institute of Child Health and Human Development

Contact: Sara Agnew
sara-agnew@uiowa.edu
319-384-0073
University of Iowa

Public Release: 27-Aug-2014
Human Genetics
Dartmouth isolates environmental influences in genome-wide association studies
Model allows researcher to remove false positive findings that plague modern research when many dozens of factors and their interactions are suggested to play a role in causing complex diseases.
National Institutes of Health

Contact: Donna Dubuc
Donna.M.Dubuc@Dartmouth.edu
603-653-3615
The Geisel School of Medicine at Dartmouth

Public Release: 27-Aug-2014
Molecular and Cellular Biology
Promising new cancer therapy uses molecular 'Trash Man' to exploit a common cancer defense
While many scientists are trying to prevent the onset of a cancer defense mechanism known as autophagy, researchers at Virginia Commonwealth University Massey Cancer Center are leveraging it in a new therapy that causes the process to culminate in cell death rather than survival.
National Institutes of Health, National Cancer Institute, Multiple Myeloma Research Foundation, Leukemia and Lymphoma Society of America

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University

Public Release: 27-Aug-2014
Nature
Worms, flies and humans... Our common genomic legacy, key to understanding cell biology
CRG researchers contribute to a project that pointed out key sets of co-expressed genes that may be fundamental for animal cells. Scientists compared the transcriptome of three very evolutionarily distant, yet well studied model organisms: the worm C. elegans, the fly D. melanogaster and the human H. sapiens. They found sets of genes that are co-expressed in each of the three species, all of them mainly involved in development.
NIH/National Human Genome Research Institute

Contact: Laia Cendrós
laia.cendros@crg.eu
34-933-160-237
Center for Genomic Regulation

Public Release: 27-Aug-2014
Science Translational Medicine
Malaria symptoms fade on repeat infections due to loss of immune cells, UCSF-led team says
Children who repeatedly become infected with malaria often experience no clinical symptoms with these subsequent infections, and a team led by UC San Francisco researchers has discovered that this might be due at least in part to a depletion of specific types of immune cells.
National Institutes of Health, US Centers for Disease Control and Prevention

Contact: Jeffrey Norris
jeffrey.norris@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 27-Aug-2014
Herbert Irving Comprehensive Cancer Center awarded $18 million grant
Outstanding basic research, a growing focus on translating discoveries into treatments, and a dedication to patient care have earned the Herbert Irving Comprehensive Cancer Center of Columbia University Medical Center and NewYork-Presbyterian Hospital an $18 million, five-year Cancer Center Support Grant from the National Cancer Institute.
NIH/National Cancer Institute

Contact: Lucky Tran
lt2549@columbia.edu
212-305-3689
Columbia University Medical Center

Public Release: 27-Aug-2014
PLOS ONE
Brain networks 'hyper-connected' in young adults who had depression
Functional magnetic resonance imaging may help to better predict and understand depression in young adults.
NIH/National Institute of Mental Health, UIC Center for Clinical and Translational Science

Contact: Sherri McGinnis Gonzalez
smcginn@uic.edu
312-996-8277
University of Illinois at Chicago

Public Release: 27-Aug-2014
PLOS ONE
Orphaned children can do just as well in institutions
The removal of institutions or group homes will not lead to better child well-being and could even worsen outcomes for some orphaned and separated children, according to new findings from a three-year study across five low- and middle-income countries. Children in institutions are as healthy and, in some ways, healthier than those in family-based care, according to the Duke University study.
NIH/National Institute of Child Health and Human Development

Contact: Kyle Hamilton
kyle.hamilton@chpir.org
919-613-5470
Duke University

Public Release: 27-Aug-2014
Nature
Evolution used similar molecular toolkits to shape flies, worms, and humans
Although separated by hundreds of millions of years of evolution, flies, worms, and humans share ancient patterns of gene expression, according to a massive Yale-led analysis of genomic data. Two related studies led by scientists at Harvard and Stanford, also published Aug. 28 in the same issue of the journal Nature, tell a similar story: even though humans, worms, and flies bear little obvious similarity to each other, evolution used remarkably similar molecular toolkits to shape them.
National Institutes of Health

Contact: Bill Hathaway
william.hathaway@yale.edu
203-432-1322
Yale University

Public Release: 27-Aug-2014
PLOS ONE
Xenon exposure shown to erase traumatic memories
McLean Hospital researchers are reporting that xenon gas, used in humans for anesthesia and diagnostic imaging, has the potential to be a treatment for post-traumatic stress disorder and other memory-related disorders.
National Institutes of Health Grant, O'Keefe Family Junior Investigator Award, McLean Hospital

Contact: Jenna Brown
jbrown66@partners.org
617-855-2110
McLean Hospital

Public Release: 27-Aug-2014
Nature
Flexing the brain: Why learning tasks can be difficult
Learning a new skill is easier when it is related to an ability we already have. For example, a trained pianist can learn a new melody easier than learning how to hit a tennis serve. Scientists from the Center for the Neural Basis of Cognition -- a joint program between Carnegie Mellon University and the University of Pittsburgh -- have discovered a fundamental constraint in the brain that may explain why this happens.
National Institutes of Health, National Science Foundation, Burroughs Wellcome Fund

Contact: Shilo Rea
shilo@cmu.edu
412-268-6094
Carnegie Mellon University

Public Release: 26-Aug-2014
Molecular Therapy
Attacking a rare disease at its source with gene therapy
The two main treatments for MPS I are bone marrow transplantation and intravenous enzyme replacement therapy, but these are only marginally effective or clinically impractical, especially when the disease strikes the central nervous system. Using an animal model, a team has proven the efficacy of a more elegant way to restore aberrant protein levels in the body through direct gene transfer.
National Institutes of Health, ReGenX BioSciences LLC

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 26-Aug-2014
Journal of Royal Society Interface
New technology may identify tiny strains in body tissues before injuries occur
Researchers at Washington University in St. Louis have developed algorithms to identify weak spots in tendons, muscles and bones prone to tearing or breaking. The technology, which needs to be refined before it is used in patients, one day may help pinpoint minor strains and tiny injuries in the body's tissues long before bigger problems occur.
NIH/National Institute on Arthritis and Musculoskeletal and Skin Diseases, National Science Foundation

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine

Public Release: 26-Aug-2014
Nature Communications
Introducing the multi-tasking nanoparticle
Kit Lam and colleagues from UC Davis and other institutions have created dynamic nanoparticles that could provide an arsenal of applications to diagnose and treat cancer.
NIH/National Cancer Institute, NIH/National Institute of Biomedical Imaging and Bioengineering, US Department of Defense, Prostate Cancer Foundation, Veterans Administration, California Institute for Regenerative Medicine

Contact: Dorsey Griffith
dorsey.griffith@ucdmc.ucdavis.edu
916-734-9118
University of California - Davis Health System

Public Release: 26-Aug-2014
Proceedings of the National Academy of Sciences
Sorting cells with sound waves
Researchers from MIT, Pennsylvania State University, and Carnegie Mellon University have devised a new way to separate cells by exposing them to sound waves as they flow through a tiny channel.
National Institutes of Health, National Science Foundation

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Public Release: 26-Aug-2014
Science
Unprecedented detail of intact neuronal receptor offers blueprint for drug developers
Scientists succeeded in obtaining an unprecedented view of a type of brain-cell receptor that is implicated in a range of neurological illnesses, including Alzheimer's disease, Parkinson's disease, depression, schizophrenia, autism, and ischemic injuries associated with stroke.
US Department of Energy, National Institutes of Health

Contact: Tona Kunz
tkunz@anl.gov
630-252-5560
DOE/Argonne National Laboratory

Public Release: 26-Aug-2014
Psychology of Addictive Behaviors
Study finds less domestic violence among married couples who smoke pot
New research findings from a study of 634 couples found that the more often they smoked marijuana, the less likely they were to engage in domestic violence.
NIH/National Institute on Alcohol Abuse and Alcoholism, NIH/National Institute on Drug Abuse

Contact: Cathy Wilde
cwilde@ria.buffalo.edu
716-887-3365
University at Buffalo

Public Release: 26-Aug-2014
Hebew SeniorLife researcher receives $4.5 million grant to test videos for advance directives
A new NIH-funded project will assess whether videos can help nursing home residents, family members and staff have the difficult but important conversations about advanced directives for care.
National Institutes of Health

Contact: Jennifer Davis
jdavis@hsl.harvard.edu
617-363-8282
Hebrew SeniorLife Institute for Aging Research

Public Release: 26-Aug-2014
National Science Review
Bombarded by explosive waves of information, scientists review new ways to process and analyze Big Data
Big Data presents information-bombarded society with the potential for new levels of scientific discovery, but also delivers challenges to data scientists. While holding promise to detect intricate population patterns, Big Data's massive sample size and high dimensionality introduce unique hurdles to processing this information. Scientists at Princeton University and at Johns Hopkins state that to meet these challenges, it is urgent to develop more robust statistical and computational methods, and a more advanced computing architecture.
National Science Foundation, National Institutes of Health

Contact: Jianqing Fan
jqfan@princeton.edu
Science China Press

Showing releases 26-50 out of 3459.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>

     
   

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