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Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 251-275 out of 3567.

<< < 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 > >>

Public Release: 6-Jan-2015
Injury Epidemiology
Drug overdose epidemic to recede soon
Researchers at Columbia University's Mailman School of Public Health project that the drug overdose epidemic will peak at about 50,000 annual deaths in 2017 before declining to a non-epidemic state of approximately 6,000 deaths in the year 2035 -- at roughly the same rate seen before the start of the epidemic. Results appear online in the journal Injury Epidemiology.
NIH/National Institute on Drug Abuse, National Center for Injury Prevention and Control

Contact: Timothy Paul
Columbia University's Mailman School of Public Health

Public Release: 6-Jan-2015
Cell Reports
Circadian rhythms regulate skin stem cell metabolism and expansion, UCI study finds
UC Irvine scientists studying the role of circadian rhythms in skin stem cells found that this clock plays a key role in coordinating daily metabolic cycles and cell division.
National Institutes of Health

Contact: Tom Vasich
University of California - Irvine

Public Release: 6-Jan-2015
Academic Pediatrics
Almost three-quarters of parents turn car seats to face forward too early
Many parents don't follow guidelines that call for using rear-facing car seats until age 2, according to National Poll on Children's Health data.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: Mary Masson
University of Michigan Health System

Public Release: 6-Jan-2015
Prostate Cancer and Prostatic Disease
Novel imaging technique improves prostate cancer detection
In 2014, prostate cancer was the leading cause of newly diagnosed cancers in men and the second leading cause of cancer death in men. A team of scientists and physicians from the University of California, San Diego School of Medicine, with counterparts at University of California, Los Angeles, describe a novel imaging technique that measurably improves upon current prostate imaging -- and may have significant implications for how patients with prostate cancer are ultimately treated.
NIH/National Institute of Biomedical Imaging and Bioengineering, Department of Defense, Prostate Cancer Research Program, American Cancer Society, UC San Diego Clinician Scientist Program.

Contact: Scott LaFee
University of California - San Diego

Public Release: 6-Jan-2015
American Journal of Physiology
Potential option for treating chronic kidney disease
New clinical research indicates the drug tetrahydrobiopterin may be able to dial back over-activation of the sympathetic nervous system in chronic kidney disease.
NIH/National Heart, Lung, and Blood Institute, US Department of Veterans Affairs

Contact: Quinn Eastman
Emory Health Sciences

Public Release: 6-Jan-2015
Journal of Clinical Investigation
Researchers map direct gut-brain connection
Duke scientists have mapped a cell-to-cell connection between the gut and the nervous system that may be a more direct route to signaling satiety than the release of hormones in the blood. The new system may change researchers' understanding of how we sense being full, and how that sensation might be affected by gastric bypass surgery. The findings also shed light on a potential new mechanism giving food-borne viruses access to the brain.
National Institutes of Health, US Department of Veterans Affairs

Contact: Karl Bates
Duke University

Public Release: 6-Jan-2015
Journal of Cell Biology
When DNA gets sent to time-out
For a skin cell to do its job, it must turn on a completely different set of genes than a liver cell -- and keep genes it doesn't need switched off. One way of turning off large groups of genes at once is to send them to 'time-out' at the edge of the nucleus. New research shows how DNA gets sent to the nucleus' far edge, a process critical to controlling genes and determining cell fate.
NIH/National Institute of General Medical Sciences

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 6-Jan-2015
International research effort gives neuroscientists better feeling about sense of touch
Our sense of touch is one we often take for granted, until our leg falls asleep and we aren't able to stand, or when we experience acute pain. The sense of touch also has been taken for granted in neuroscience, where it's the sense scientists know the least about. For the first time researchers have linked a group of neurons to a specific type of somatosensation, a finding that can open the door for a heightened understanding about our sense of touch.
Deutsche Forschungsgemeinschaft, European Research Council, Alexander von Humboldt Foundation, European Union, National Institutes of Health

Contact: Jocelyn Duffy
Carnegie Mellon University

Public Release: 6-Jan-2015
Molecular Psychiatry
New picture, new insight
Using a different type of MRI imaging, researchers at the University of Iowa have discovered previously unrecognized differences in the brains of patients with bipolar disorder. In particular, the study, published Jan. 6 in the journal Molecular Psychiatry, revealed differences in the white matter of patients' brains and in the cerebellum, an area of the brain not previously linked with the disorder.
NIH/National Institute of Mental Health, NIH/National Heart, Lung and Blood Institute, US Department of Veterans Affairs, NARSAD

Contact: Jennifer Brown
University of Iowa Health Care

Public Release: 6-Jan-2015
Science Signaling
Researchers uncover key cancer-promoting gene
One of the mysteries in cancer biology is how one protein, TGF-beta, can both stop cancer from forming and encourage its aggressive growth. Now, researchers at the University of Michigan Comprehensive Cancer Center have uncovered a key gene that may explain this paradox and provide a potential target for treatment.
NIH/National Cancer Institute, National Science Foundation

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 6-Jan-2015
Journal of Parenteral and Enteral Nutrition
Poor vitamin D status linked to longer respiratory support in ICU patients, study finds
Vitamin D status may influence the duration of respiratory support needed for surgical intensive care patients, according to a new cohort study conducted by researchers at Boston's Massachusetts General Hospital and Harvard Medical School.
National Institutes of Health

Contact: Troy Petenbrink
American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)

Public Release: 6-Jan-2015
Cell Metabolism
Researchers identify new genetic and epigenetic contributors to diabetes
An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say. Their findings reveal that obesity-induced changes to the epigenome -- reversible chemical 'tags' on DNA -- are surprisingly similar in mice and humans, and might provide a new route to prevention and treatment of the disease, which affects hundreds of millions worldwide.
NIH/National Institute of Environmental Health Sciences, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Novo Nordisk Foundation and Stockholm County Council, European Research Council

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 6-Jan-2015
Landmark trial: Early blood glucose control extends life in people with type 1 diabetes
People with type 1 diabetes who intensively control their blood glucose soon after diagnosis are likely to live longer than those who do not. Data from a long-running trial and follow-up observational study showed a 33 percent reduction in deaths over the past several decades among participants who had early, good control of their blood glucose.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 6-Jan-2015
Cell Metabolism
Drug stimulates brown fat and boosts metabolism
Researchers publishing in the Jan. 6 issue of Cell Metabolism have discovered that a drug FDA-approved to treat overactive bladder may boost brown fat's metabolic powers, making it a promising candidate for combatting obesity. Unlike energy-storing white fat, brown fat burns energy to generate heat, which can help maintain body weight and prevent obesity in rodents.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Joseph Caputo
Cell Press

Public Release: 6-Jan-2015
PLOS Medicine
RSV infection may be associated with higher risk for bacterial pneumonia
Two common and sometimes dangerous respiratory diseases, a viral one caused by respiratory syncytial virus (RSV), and a bacterial one caused by Streptococcus pneumoniae may be linked, suggests a study published in this week's PLOS Medicine. Daniel Weinberger, from Yale University School of Public Health, and colleagues, analyzed hospitalization data to investigate a possible association between RSV and pneumonia in young children, and found that infection with RSV may increase the risk of pneumonia.
Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Yale University/Claude D. Pepper Older Americans Independence Center, Yale Center for Clinical Investigation

Contact: Maya Sandler

Public Release: 5-Jan-2015
Journal of Molecular and Cellular Cardiology
Why do only some people with hereditary heart disease experience symptoms?
For the first time, researchers have found that, in addition to gene mutations, environmental stress plays a key role in the development of hypertrophic cardiomyopathy.
NIH/National Heart, Lung and Blood Institute, American Heart Association

Contact: Jim Ritter
Loyola University Health System

Public Release: 5-Jan-2015
UMMS to develop a model for predicting gene expression in dendritic cells
Deciphering the language of gene expression, UMMS scientists Jeremy Luban, M.D., and Manuel Garber, Ph.D., received $6.1 million from the NIH to develop a model system for exploring gene regulation using human dendritic cells.
National Institutes of Health

Contact: Jim Fessenden
University of Massachusetts Medical School

Public Release: 5-Jan-2015
Cell Reports
A novel biomarker for mutant p53 could help pathologists assessing tumors during surgery
Researchers at Cold Spring Harbor Laboratory today report the discovery of a novel cellular biomarker that could make it comparatively easy for cancer surgeons to determine if a patient has a potentially lethal mutation in a protein called p53, the most powerful of the body's natural tumor suppressors and often called 'the guardian of the genome.' The biomarker's identity surprised the team.
The American Cancer Society, Pershing Square Sohn Foundation, National Institutes of Health, Robertson Research Fund of CSHL, NIH Cancer Center, Lustgarten Foundation for Pancreatic Cancer Research

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 5-Jan-2015
Nature Communications
Scientists discover new information about how enzymes from white blood cells function
Researchers at the University of Missouri, have determined that one of these enzymes, known as MMP12, does not remain outside of cells while it fights infections, but rather it can travel all the way to the center of cells. Understanding how this and other enzymes function is an important step to creating treatments for inflammatory diseases.
National Institutes of Health

Contact: Nathan Hurst
University of Missouri-Columbia

Public Release: 5-Jan-2015
Molecular Therapy
'CRISPR' science: Newer genome editing tool shows promise in engineering human stem cells
A powerful 'genome editing' technology known as CRISPR has been used by researchers since 2012 to trim, disrupt, replace or add to sequences of an organism's DNA. Now, scientists at Johns Hopkins Medicine have shown that the system also precisely and efficiently alters human stem cells.
Maryland Stem Cell Research Fund, NIH/National Heart, Lung, and Blood Institute

Contact: Marin Hedin
Johns Hopkins Medicine

Public Release: 5-Jan-2015
Alcohol taxes protective against binge drinking, study shows
Higher alcohol taxes strongly protect against binge drinking, according to a new study by Boston University School of Public Health researchers.
National Institutes of Health

Contact: Lisa Chedekel
Boston University Medical Center

Public Release: 5-Jan-2015
Cell Reports
Imaging linking cell activity and behavior shows what it means for mice to have sex in mind
An automated method (much more sensitive than fMRI) to detect the activity of neurons during specific behaviors, at the resolution of individual brain cells throughout the entire mouse brain, has been successfully demonstrated. A team shows brain activation patterns when male mice perform two critical tasks: recognizing other individuals and determining the sex of another individual.
NIH/National Institute of Mental Health, Simons Foundation for Autism Research, Allen Institute for Brain Science, Howard Hughes Medical Institute, Gatsby Charitable Foundation

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 5-Jan-2015
American Journal of Clinical Nutrition
Vitamin B may counter negative effect of pesticide on fertility
Women who have adequate levels of B vitamins in their bodies are more likely to get and stay pregnant even when they also have high levels of a common pesticide known to have detrimental reproductive effects, according to new Johns Hopkins Bloomberg School of Public Health research.
NIH/National Institute of Child Health and Human Development, NIH/National Institute of Environmental Health Sciences

Contact: Stephanie Desmon
Johns Hopkins University Bloomberg School of Public Health

Public Release: 5-Jan-2015
Animal study points to a treatment for Huntington's disease
By adjusting the levels of a key signaling protein, researchers improved motor function and brain abnormalities in experimental animals with a form of Huntington's disease, a severe neurodegenerative disorder. The new findings may lay the groundwork for a novel treatment for people with this fatal, progressive disease.
National Institutes of Health, Roy J. Carver Trust

Contact: John Ascenzi
Children's Hospital of Philadelphia

Public Release: 5-Jan-2015
Nature Cell Biology
Epigenomics analysis reveals surprising new clues to insulin resistance
In studying the cellular structure and function of insulin, a research team led by investigators at Beth Israel Deaconess Medical Center has uncovered previously unknown steps in the development of insulin resistance.
National Institutes of Health, American Diabetes Association, American Heart Association

Contact: Bonnie Prescott
Beth Israel Deaconess Medical Center

Showing releases 251-275 out of 3567.

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