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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 251-275 out of 3806.

<< < 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 > >>

Public Release: 6-Jul-2015
Proceedings of the National Academy of Sciences
Heart attack treatment hypothesis 'busted'
Researchers have long had reason to hope that blocking the flow of calcium into the mitochondria of heart and brain cells could be one way to prevent damage caused by heart attacks and strokes. But in a study of mice engineered to lack a key calcium channel in their heart cells, Johns Hopkins scientists appear to have cast a shadow of doubt on that theory. A report on their study is published online this week in Proceedings of the National Academy of Sciences.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute of General Medical Sciences, National Center for Research Resources, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Veterans Administration, and others

Contact: Lauren Nelson
Johns Hopkins Medicine

Public Release: 6-Jul-2015
Study explains how dengue virus adapts as it travels, increasing chances for outbreaks
A researcher from The University of Texas Medical Branch at Galveston is an integral member of a collaborative group that is the first to explain the mechanisms that the Dengue virus has developed to optimize its ability to cause outbreaks as it travels across the globe to new places and revisits old ones.
The Singapore National Medical Research Council, Ministry of Health in Singapore, Institute of Molecular and Cell Biology, Agency of Science, Technology and Research in Singapore, National Institutes of Health

Contact: Donna Ramirez
University of Texas Medical Branch at Galveston

Public Release: 6-Jul-2015
Reducing stroke damage may be next for OCT technology widely used in vision healthcare
A new article by University of Washington researchers in the journal Neurophotonics, published by SPIE, the international society for optics and photonics, reports on use of optical coherence tomography to obtain high-resolution images showing blood-flow dynamics in the brain before, during, and after stroke-like states. The information may ultimately enable clinicians to reduce stroke damage.
National Institutes of Health

Contact: Amy Nelson
SPIE--International Society for Optics and Photonics

Public Release: 6-Jul-2015
Psychology of Addictive Behaviors
Adolescents who view medical marijuana ads more likely to use the drug, study finds
A new study raises questions about whether there is a need to revise prevention programming for youth as the availability, visibility and legal status of marijuana changes. The report found that adolescents who saw advertising for medical marijuana were more likely to either report using marijuana or say they planned to use the substance in the future.
NIH/National Institute of Alcohol Abuse and Alcoholism

Contact: Warren Robak
RAND Corporation

Public Release: 6-Jul-2015
Blacklegged tick populations have expanded via migration, Penn biologists show
In a new study, biologists from the University of Pennsylvania used genetic and phylogeographic analyses to determine the origin and recent migratory history of newly discovered tick populations in the Northeastern United States. Their findings indicate that the ticks moved into new areas from established populations, mainly through short-distance, local moves.
National Institutes of Health, Burroughs Wellcome Fund

Contact: Katherine Unger Baillie
University of Pennsylvania

Public Release: 6-Jul-2015
Temple-led research team finds bacterial biofilms may play a role in lupus
Lupus, multiple sclerosis, and type-1 diabetes are among more than a score of diseases in which the immune system attacks the body. But why the immune system begins its misdirected assault has remained a mystery. Now, researchers at Temple University School of Medicine have shown that bacterial communities known as biofilm play a role in the development of the autoimmune disease systemic lupus erythematosus -- a discovery that may provide important clues about several autoimmune ailments.
National Institutes of Health, NIH/National Institutes of Allergy and Infectious Diseases, Fox Chase Cancer Center-Temple University Nodal Grant, Lupus Research Institute Innovation Research Grant, Lupus Foundation's Goldie Simon Preceptorship Award, etc.

Contact: Jeremy Walter
Temple University Health System

Public Release: 6-Jul-2015
Nature Communications
How to rule a gene galaxy: A lesson from developing neurons
A new study published in Nature Communications by researchers from the MRC Centre for Developmental Neurobiology at IoPPN, carried out in collaboration with the Tian lab at the Rutgers New Jersey Medical School, found that many RNA messengers encoding neuronal proteins contain specialized sequences that can promote their destabilization in the presence of an RNA-binding protein called tristetraprolin, or TTP.
Biotechnology and Biosciences Research Council, National Institutes of Health, National Medical Research Council

Contact: Andreia Carvalho
King's College London

Public Release: 6-Jul-2015
Journal of Biological Chemistry
Ion channel mechanics yield insights into optogenetics experiments
Optogenetics techniques, which allow scientists to map and control nerve cells using light stimulation, are being used to study neural circuits in the brain with unprecedented precision. This revolutionary technology relies on light-sensitive proteins such as channelrhodopsins, and researchers at UC Santa Cruz have now determined the molecular mechanism involved in the light-induced activation of one of these proteins.
National Institutes of Health

Contact: Tim Stephens
University of California - Santa Cruz

Public Release: 6-Jul-2015
Cutting big data down to a usable size
Next-generation DNA sequencing technologies have turned the vision of precision medicine into a plausible reality, but also threaten to overwhelm computing infrastructures with unprecedented volumes of data. A recent $1.3 million award from the National Institutes of Health will allow researchers at the University of Illinois and Stanford to help address this challenge by developing novel data compression strategies.
National Institutes of Health, National Institutes of Health Big Data to Knowledge Initiative

Contact: Nicholas Vasi
Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign

Public Release: 6-Jul-2015
Nature Medicine
Fundamental beliefs about atherosclerosis overturned
Doctors' efforts to battle the dangerous atherosclerotic plaques that build up in our arteries and cause heart attacks and strokes are built on several false beliefs about the fundamental composition and formation of the plaques, new research from the University of Virginia School of Medicine shows. These new discoveries will force researchers to reassess their approaches to developing treatments and discard some of their basic assumptions about atherosclerosis, commonly known as hardening of the arteries.
National Institutes of Health, American Heart Association

Contact: Josh Barney
University of Virginia Health System

Public Release: 6-Jul-2015
Nature Medicine
Age-related cognitive decline tied to immune-system molecule
Researchers at UC San Francisco and Stanford School of Medicine have shown that a blood-borne molecule that increases in abundance as we age blocks regeneration of brain cells and promotes cognitive decline.
California Institute for Regenerative Medicine, National Science Foundation, US Department of Veterans Affairs, NIH/National Institute on Aging, Sandler Foundation, Marc and Lynne Benioff, UCSF Clinical and Translational Science Institute

Contact: Pete Farley
University of California - San Francisco

Public Release: 6-Jul-2015
Proceedings of the National Academy of Sciences
Why don't men live as long as women?
Across the entire world, women can expect to live longer than men. But why does this occur, and was this always the case? A new USC-led study reveals that vulnerability to heart disease is the biggest culprit behind a surge in higher death rates for men versus women during the 20th century.
NIH/National Institute on Aging

Contact: Beth Newcomb
University of Southern California

Public Release: 6-Jul-2015
Proceedings of the National Academy of Sciences
Brain imaging shows how children inherit their parents' anxiety
A study in an extended family of monkeys provides important insights into how the risk of developing anxiety and depression is passed from parents to children. The study from the Department of Psychiatry and the Health Emotions Research Institute at the University of Wisconsin-Madison shows how an over-active brain circuit involving three brain areas inherited from generation to generation may set the stage for developing anxiety and depressive disorders.
NIH/National Institute of Mental Health

Contact: Susan Lampert Smith
University of Wisconsin-Madison

Public Release: 6-Jul-2015
Nature Structural & Molecular Biology
Protein suggests a new strategy to thwart infection
The newfound ability of a protein of the intestines and lungs to distinguish between human cells and the cells of bacterial invaders could underpin new strategies to fight infections. Writing this week in the journal Nature Structural and Molecular Biology, a team led by University of Wisconsin-Madison Professor Laura Kiessling describes the knack of a human protein known as intelectin to distinguish between our cells and those of the disease-causing microbes that invade our bodies.
National Institutes of Health

Contact: Laura Kiessling
University of Wisconsin-Madison

Public Release: 6-Jul-2015
Journal of the American College of Cardiology
Extra heartbeats could be modifiable risk factor for congestive heart failure
Common extra heartbeats known as premature ventricular contractions may be a modifiable risk factor for congestive heart failure and death, according to researchers at UC San Francisco.
American Heart Association, Joseph Drown Foundation, NIH/National Heart, Lung, Blood Institute, NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute on Aging

Contact: Scott Maier
University of California - San Francisco

Public Release: 6-Jul-2015
Annals of Internal Medicine
Typically disregarded brain lesions may warn of heightened stroke risk
Scientists with the University of Mississippi Medical Center and colleagues found that very small brain lesions noted on brain imaging that would typically be disregarded by clinicians are associated with a heightened risk of stroke and death. The discovery about these tiny lesions -- areas of the brain where tissue may have been damaged by injury or disease -- may help physicians identify people at risk of stroke and death as early as middle age.
NIH/National Heart Lung and Blood Institute

Contact: Dustin Barnes
University of Mississippi Medical Center

Public Release: 6-Jul-2015
Proceedings of the National Academy of Sciences
Researchers learn to measure aging process in young adults
A research team from the US, UK, Israel and New Zealand has identified multiple health factors that may be combined to determine whether people are aging faster or slower than their peers. They determined both a biological age and a pace of aging for study participants from age 26 to 38.
New Zealand Health Research Council, NIH/National Institute on Aging, Medical Research Council, Jacobs Foundation, Yad Hanadiv Rothschild Foundation

Contact: Karl Leif Bates
Duke University

Public Release: 6-Jul-2015
Nature Cell Biology
New paradigm for treating 'inflammaging' and cancer
Intermittent dosing with rapamycin breaks the inflammatory loop associated with senescence. Once disrupted, it takes time for the loop to reestablish itself -- providing proof-of-principal that intermittent dosing could provide a way to reap the benefits of rapamycin while bypassing its safety issues. The FDA-approved drug increases healthspan and lifespan in mice. DNA-damaging chemotherapies cause senescence in the tumor microenvironment. In mice, intermittent dosing blocked the inflammation believed to fuel the proliferation of residual cancer cells.
National Institutes of Health, Hillblom Medical Foundation, National Natural Science Foundation of China, Prostate Cancer Foundation

Contact: Kris Rebillot
Buck Institute for Age Research

Public Release: 3-Jul-2015
Science Advances
REM sleep critical for young brain development; medication interferes
Rapid eye movement or REM sleep actively converts waking experiences into lasting memories and abilities in young brains reports a new study from Washington State University Spokane. The finding, published in Science Advances, broadens the understanding of children's sleep needs and calls into question the increasing use of REM-disrupting medications such as stimulants and antidepressants.
National Institutes of Health

Contact: Marcos Frank
Washington State University

Public Release: 2-Jul-2015
Cell Reports
Long-term memories are maintained by prion-like proteins
Research from Eric Kandel's lab has uncovered further evidence of a system in the brain that persistently maintains memories for long periods of time.
National Institutes of Health

Contact: Karin Eskenazi
Columbia University Medical Center

Public Release: 2-Jul-2015
Cell Stem Cell
New measurements reveal differences between stem cells for treating retinal degeneration
By growing two types of stem cells in a '3-D culture' and measuring their ability to produce retinal cells, a team lead by St. Jude Children's Research Hospital researchers has found one cell type to be better at producing retinal cells.
National Institutes of Health, Howard Hughes Medical Institute, Alex's Lemonade Stand Foundation for Childhood Cancer and ALSAC

Contact: Frannie Marmorstein
St. Jude Children's Research Hospital

Public Release: 2-Jul-2015
American Journal of Hypertension
Two new studies on the connection between hypertension and cognitive decline
With the number of individuals affected by cognitive decline expected to rise over the next few decades, investigating its potential causes is of major public health interest. Two new studies published today in the American Journal of Hypertension delve into the connection between hypertension and cognitive decline.
NIH/National Heart, Lung, and Blood Institute, National Institutes of Health, US Department of Health and Human Services

Contact: Molly Grote
Oxford University Press USA

Public Release: 2-Jul-2015
Journal of the American Heart Association
Review indicates where cardio benefits of exercise may lie
A systematic review of 160 clinical trials of the cardiometabolic benefits of exercise shows which health indicators improve most with physical activity and for whom. For example, some of the benefits are greater for men, people under 50 and among those battling type 2 diabetes or other cardiovascular conditions.
National Institutes of Health, Brown University, Indiana University

Contact: David Orenstein
Brown University

Public Release: 2-Jul-2015
Mosquito-borne viruses subject of $4 million in federal grants to Pitt vaccine researchers
Scientists at the University of Pittsburgh Center for Vaccine Research recently received nearly $4 million through five federal grants to study a group of related mosquito-borne viruses. The ultimate goal is to develop vaccines and therapies against the deadly diseases.
National Institutes of Health, US Department of Defense

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 2-Jul-2015
Investigational HIV vaccine regimen shows encouraging results in non-human primates
Johnson & Johnson announced today that scientists at Beth Israel Deaconess Medical Center, Crucell Holland B.V, and several other collaborators today published results from a preclinical study of an HIV vaccine regimen used in in non-human primates. The study, published in the online edition of Science, suggests that a 'heterologous prime-boost' vaccine regimen -- could ultimately prove to be a strategy for protecting against global human immunodeficiency virus infection.
National Institutes of Health, Bill & Melinda Gates Foundation, The Ragon Institute of Massachusetts General Hospital, MIT, Harvard

Contact: Seema Kumar
Johnson & Johnson

Showing releases 251-275 out of 3806.

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