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Department of Health and Human Services

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Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 251-275 out of 3673.

<< < 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 > >>

Public Release: 6-Apr-2015
Proceedings of the National Academy of Sciences
Characteristic pattern of protein deposits in brains of retired NFL players who suffered concussions
A new UCLA study takes another step toward the early understanding of a degenerative brain condition called chronic traumatic encephalopathy, or CTE, which affects athletes in contact sports who are exposed to repetitive brain injuries. Using a new imaging tool, researchers found a strikingly similar pattern of abnormal protein deposits in the brains of retired NFL players who suffered from concussions.
National Institutes of Health, Toulmin Foundation and Robert and Marion Wilson

Contact: Rachel Champeau
University of California - Los Angeles Health Sciences

Public Release: 6-Apr-2015
Psychosomatic Medicine
Common antidepressant increased coronary atherosclerosis in animal model
A commonly prescribed antidepressant caused up to a six-fold increase in atherosclerosis plaque in the coronary arteries of non-human primates, according to a study by researchers at Wake Forest Baptist Medical Center. Coronary artery atherosclerosis is the primary cause of heart attacks.
National Institutes of Health

Contact: Marguerite Beck
Wake Forest Baptist Medical Center

Public Release: 6-Apr-2015
Proceedings of the National Academy of Sciences
Study reveals Internet-style 'local area networks' in cerebral cortex of rats
Studying 40 years' worth of data on rat brains, scientists found that the rat cerebral cortex has hubs and 'local area networks,' much like the Internet.
National Institutes of Health

Contact: Robert Perkins
University of Southern California

Public Release: 6-Apr-2015
Tobacco Control
Women smokers concerned about weight are less likely to try to quit
Women who believe smoking helps them manage their weight are less likely to try quitting in response to anti-smoking policies than other female smokers in the US. The study, published online in the journal Tobacco Control, is the first to find that smokers who are concerned about their weight are less swayed by anti-smoking policies -- such as bumps in cigarette prices, smoke-free laws or anti-tobacco messaging -- than other smokers are.
Roswell Park, NIH/National Cancer Institute, Robert Wood Johnson Foundation, Canadian Institutes of Health and Research, Commonwealth Department of Health and Aging, Canadian Tobacco Control Research Initiative

Contact: Sharon Parmet
University of Illinois at Chicago

Public Release: 6-Apr-2015
Nature Neuroscience
CU researchers: Brain activity boosts processes that promote neural connections
Brain activity affects the way the developing brain connects neurons and a study by researchers at the School of Medicine on the University of Colorado Anschutz Medical Campus and Children's Hospital Colorado suggests a new model for understanding that process.
National Institutes of Health, Gates Frontiers Fund, National Multiple Sclerosis Postdoctoral Fellowship

Contact: Mark Couch
University of Colorado Denver

Public Release: 6-Apr-2015
Nature Immunology
Study identifies protein that triggers lupus-associated immune system activation
Massachusetts General Hospital investigators have found that a protein that regulates certain cells in the innate immune system -- the body's first line of defense against infection -- activates a molecular pathway known to be associated with the autoimmune disorder systemic lupus erythematosus and that the protein's activity is required for the development of lupus symptoms in a mouse model of the disease.
National Institutes of Health, Lupus Research Institute, Alliance for Lupus Research, American Society of Nephrology

Contact: Sue McGreevey
Massachusetts General Hospital

Public Release: 6-Apr-2015
Cancer Epidemiology, Biomarkers & Prevention
Childhood cancer survivors face chronic health problems
Childhood cancer survivors have increased, but the majority of those who have survived face chronic health problems, diseases and disability related to treatment, reports a new study. The study is the first to estimate the national prevalence of treatment-related chronic disease among survivors of childhood cancer. Simply curing cancer is no longer enough, scientists said.
National Institutes of Health

Contact: Marla Paul
Northwestern University

Public Release: 6-Apr-2015
Stroke: Journal of the American Heart Association
Women and men have different exclusion criteria for rtPA
After analyzing stroke treatment records, researchers at Rhode Island Hospital in collaboration with researchers from the University of Cincinnati learned that women and men have different reasons for being excluded from receiving the common clot-dissolving drug, recombinant tissue plasminogen activator. Importantly, more women had very high blood pressures, which reduced their eligibility to be treated with the highly effective drug. The study was recently published in the American Heart Association's journal, Stroke.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Beth Bailey

Public Release: 6-Apr-2015
Proceedings of the National Academy of Sciences
Device extracts rare tumor cells using sound
A simple blood test may one day replace invasive biopsies thanks to a new device that uses sound waves to separate blood-borne cancer cells from white blood cells. Carnegie Mellon University President Subra Suresh and fellow researchers from the Massachusetts Institute of Technology and The Pennsylvania State University report the latest advancement that brings their device one step closer to clinical use in a paper published this week in the online early edition of the Proceedings of the National Academy of Sciences.
National Institutes of Health, Penn State Center for Nano Scale Science, National Science Foundation

Contact: Jocelyn Duffy
Carnegie Mellon University

Public Release: 6-Apr-2015
New target for anticancer drugs: RNA
Messenger RNAs -- the working copies of genes that are used to assemble proteins -- have typically been ignored as drug targets because they all look about the same. But UC Berkeley researchers have found that a subset of mRNAs -- many of which have been linked to cancer -- have unique tags. These short RNA tags bind to a protein, eIF3, that regulates translation at the ribosome, making the binding site a promising target for anticancer drugs.
NIH/National Institute of General Medical Sciences

Contact: Robert Sanders
University of California - Berkeley

Public Release: 6-Apr-2015
Journal of Clinical Oncology
A third of breast cancer patients concerned about genetic risk
A new study from the University of Michigan Comprehensive Cancer Center finds that many women diagnosed with breast cancer are concerned about the genetic risk of developing other cancers themselves or of a loved one developing cancer.
NIH/National Cancer Institute, American Cancer Society

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 6-Apr-2015
Nature Biotechnology
Pulling the strings of our genetic puppetmasters
Researchers have developed a new method to activate genes by synthetically creating a key component of the epigenome that controls how our genes are expressed. The new technology allows researchers to turn on specific gene promoters and enhancers -- pieces of our genomes that control our genes' activity -- by chemically manipulating proteins that package our DNA.
National Institutes of Health, National Science Foundation

Contact: Ken Kingery
Duke University

Public Release: 6-Apr-2015
Young guns: Study finds high firearm violence rate in high-risk youth after assault injury
Two young men sit in an inner-city emergency room. One is getting care for injuries he suffered in a fight, the other, for a sore throat. After getting care, both head back out to an environment of violence and poverty. But, a new study finds, the one who had been in a fight will have a nearly 60 percent chance of becoming involved in a violent incident involving a firearm within the next two years.
NIH/National Institute on Drug Abuse, NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Kara Gavin
University of Michigan Health System

Public Release: 6-Apr-2015
Health Affairs
Emergency rooms see rising rate of patients with chronic conditions, lower rate of injuries
The rate of emergency department visits in California for non-injuries has risen while the rate of visits for injuries has dropped, according to a new study led by University of California San Francisco that documents the increasing amount of care provided in emergency departments for complex, chronic conditions.
California HealthCare Foundation, National Center for Advancing Translational Sciences, National Institutes of Health, UCSF Clinical & Translational Science Institute, Robert Wood Johnson Foundation

Contact: Elizabeth Fernandez
University of California - San Francisco

Public Release: 6-Apr-2015
JAMA Internal Medicine
Lower extremity revascularization not effective in majority of nursing home residents
Only a few US nursing home residents who undergo lower extremity revascularization procedures are alive and ambulatory a year after surgery, according to UCSF researchers, and most patients still alive gained little, if any, function.
NIH/National Institute on Aging, Paul B. Beeson Clinical Scientist Development Award in Agin, UCSF Claude D. Pepper Older Americans Independence Center

Contact: Scott Maier
University of California - San Francisco

Public Release: 6-Apr-2015
Annals of Internal Medicine
Physical therapy, surgery produce same results for stenosis in older patients
Pitt researchers find equal outcomes in a two-year study, but policy issues may lurk underneath lumbar spinal stenosis issues.
National Institutes of Health, NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Chuck Finder
University of Pittsburgh Schools of the Health Sciences

Public Release: 6-Apr-2015
Circulation: Journal of the American Heart Association
Physically active middle-aged adults have low risk of sudden cardiac arrest
The incidence of sudden cardiac arrest during sports activities is relatively low among physically active middle-aged adults. Education and preventive measures can further lower risk of sports-related sudden cardiac death in middle-aged adults.
NIH/National Heart, Lung, and Blood Institute

Contact: Akeem Ranmal
American Heart Association

Public Release: 6-Apr-2015
Annals of Internal Medicine
Few commercial weight-loss programs show evidence of effectiveness, Johns Hopkins reports
In a bid to help physicians guide obese and overweight patients who want to try a commercial weight-loss program, a team of Johns Hopkins researchers reviewed 4,200 studies for solid evidence of their effectiveness but concluded only a few dozen of the studies met the scientific gold standard of reliability
NIH/National Heart, Lung and Blood Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, JHU-UMD Diabetes Research Center, Dean's Office Summer Research Funding

Contact: Heather Dewar
Johns Hopkins Medicine

Public Release: 3-Apr-2015
UCLA research links HIV to age-accelerating cellular changes
People undergoing treatment for HIV-1 have an increased risk for earlier onset of age-related illnesses such as some cancers, renal and kidney disease, frailty, osteoporosis and neurocognitive disease. But is it because of the virus that causes AIDS or the treatment? New research suggests that HIV itself accelerates these aging related changes by more than 14 years.
NIH/National Institute on Aging grant, UCLA AIDS Institute/CFAR seed grant from the National Institutes of Health, NIH T032 training grant, National Science Foundation grant

Contact: Enrique Rivero
University of California - Los Angeles Health Sciences

Public Release: 3-Apr-2015
Science Advances
Targeting dangerous inflammation inside artery plaque
A research team showed that a nanotherapeutic medicine can halt the growth of artery plaque cells resulting in the fast reduction of the inflammation that may cause a heart attack.
NIH/National Heart, Lung, and Blood Institute, NIH/Program of Excellence in Nanotechnology Award, National Institutes of Health,Harold S. Geneen Charitable Trust Award, and others

Contact: Lauren Woods
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 3-Apr-2015
American Journal of Human Genetics
New genetic clues emerge on origin of Hirschsprung's disease
Genetic studies in humans, zebrafish and mice have revealed how two different types of genetic variations team up to cause a rare condition called Hirschsprung's disease. The findings add to an increasingly clear picture of how flaws in early nerve development lead to poor colon function, which must often be surgically corrected. The study also provides a window into normal nerve development and the genes that direct it.
NIH/National Institute of Child Health and Human Development, NIH/National Institute for General Medical Sciences, National Natural Science Foundation of China, Beijing Natural Science Foundation, Beijing Excellent Scientist Fund, and others

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 3-Apr-2015
Case Western Reserve to lead international research on resistance to bacteria causing TB
After discovering a unique group of people resistant to tuberculosis (TB) infection, Case Western Reserve researchers are leading an international team dedicated to understanding exactly how they fight off a disease that claims 1.5 million lives each year. The team's goal is to use lessons learned from these resistant individuals to develop an approach to treating and curing TB that is unlike any existing medication.
National Institutes of Health, Bill & Melinda Gates Foundation

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 3-Apr-2015
Science Advances
CRISPR-Cas editing of C. albicans holds promise for overcoming deadly fungal infections
Candida albicans is a human pathogen that causes potentially lethal infections in immunocompromised individuals. Efforts to overcome Candida's innate resistance to many drugs have been thwarted by an absence of tools enabling genetic modifications. Now, using a modified CRISPR-Cas system, Whitehead Institute researchers can edit the fungus's genome systematically -- an approach that could help scientists understand Candida's unique biology and identify potential drug targets.
National Institutes of Health

Contact: Nicole Giese Rura
Whitehead Institute for Biomedical Research

Public Release: 3-Apr-2015
PLOS Pathogens
Rice can borrow stronger immunity from other plant species, study shows
Rice, one of the world's main staple foods, can boost its built-in immunity against invading disease-causing microbes when immune receptor genes are transferred via genetic engineering from a totally different plant group, this new study shows.
European Molecular Biology Organization, Human Frontier Science Program Organization of France, Gatsby Charitable Foundation in London, US Department of Energy, and National Institutes of Health

Contact: Patricia Bailey
University of California - Davis

Public Release: 2-Apr-2015
Journal of the National Cancer Institute
Mayo Clinic researchers combine common genetic variants to improve breast cancer
Recent large-scale genomic analyses have uncovered dozens of common genetic variants that are associated with breast cancer. Each variant, however, contributes only a tiny amount to a person's overall risk of developing the disease.
NIH/National Cancer Institute, Breast Cancer Research Foundation

Contact: Joe Dangor
Mayo Clinic

Showing releases 251-275 out of 3673.

<< < 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 > >>


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