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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 251-275 out of 3606.

<< < 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 > >>

Public Release: 4-Feb-2015
eLife
TSRI scientists find more DNA and extra copies of disease gene in Alzheimer's brain cells
Scientists at The Scripps Research Institute have found diverse genomic changes in single neurons from the brains of Alzheimer's patients, pointing to an unexpected factor that may underpin the most common form of the disease. A new study shows that Alzheimer's brains commonly have many neurons with significantly more DNA and genomic copies of the Alzheimer's-linked gene, APP, than normal brains.
National Institutes of Health, Shaffer Family Foundation.

Contact: Madeline McCurry-Schmidt
madms@scripps.edu
858-784-9254
Scripps Research Institute

Public Release: 4-Feb-2015
Journal of Neuroscience
Anti-epilepsy drug preserves brain function after stroke
New research conducted in the School of Medicine at The University of Texas Health Science Center at San Antonio suggests that an already-approved drug could dramatically reduce the debilitating impact of strokes, which affect nearly a million Americans every year.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Will Sansom
sansom@uthscsa.edu
210-567-2579
University of Texas Health Science Center at San Antonio

Public Release: 4-Feb-2015
Annals of Surgery
Bariatric surgery may reduce life expectancy for super obese diabetic patients
Bariatric surgery improves life expectancy for many obese diabetic patients, but it may cut life expectancy for patients who are super obese with very high body mass indexes, according to a University of Cincinnati researcher.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Cedric Ricks
cedric.ricks@uc.edu
513-558-4657
University of Cincinnati Academic Health Center

Public Release: 4-Feb-2015
Neuropsychopharmacology
Brain scans predict effectiveness of talk therapy to treat depression
UNC School of Medicine researchers have shown that brain scans can predict which patients with clinical depression are most likely to benefit from a specific kind of talk therapy.
National Institutes of Health, UNC Building Interdisciplinary Careers in Women's Health Career Development Program, UNC Neuroscience Center

Contact: Mark Derewicz
mark.derewicz@unchealth.unc.edu
919-923-0959
University of North Carolina Health Care

Public Release: 4-Feb-2015
Neuropsychopharmacology
Researchers identify peptide that reduces urge to eat
Researchers have identified a peptide and hormone that when administered to a specific area of the brain may reduce the desire for food. The study, which appears in the journal Neuropsychopharmacology, may one day lead to medications that treat obesity and binge eating disorders.
NIH/National Institute of Mental Health, NIH/National Institute on Drug Abuse, Peter Paul Career Development Professorship, Peter McManus Charitable Trust, Boston University

Contact: Gina DiGravio
ginad@bu.edu
617-638-8480
Boston University Medical Center

Public Release: 4-Feb-2015
ACS Nano
New nanoparticle gene therapy strategy effectively treats deadly brain cancer in rats
New insights into specific gene mutations that arise in glioma, an often deadly form of brain cancer, have pointed to the potential of gene therapy, but it's very difficult to effectively deliver toxic or missing genes to cancer cells in the brain. Now, researchers have used nanoparticles to deliver a new therapy to glioma cells in the brains of rats, prolonging their lives.
NIH/National Institute of Biomedical Imaging and Bioengineering

Contact: Heather Dewar
hdewar1@jhmi.edu
410-502-9463
Johns Hopkins Medicine

Public Release: 4-Feb-2015
Nature Communications
Newly discovered protein has link to gestational diabetes
For at least 40 years, scientists who study how the body metabolizes sugar have accepted one point: there are four enzymes that kick-start the body's process of getting energy from food. But this biochemical foursome may not deserve all of the credit. According to research by scientists at Duke and Northwestern universities, the hexokinase team actually has a fifth player.
National Institutes of Health, Department of Veterans Affairs

Contact: Samiha Khanna
samiha.khanna@duke.edu
919-419-5069
Duke University Medical Center

Public Release: 4-Feb-2015
Neuron
Attention! How eyes reveal the brain's focus
A primate's ability to pay attention to, or tune out, particular sights and sounds is crucial for success and survival. Duke University researchers looked into monkeys' eyes for insight into how the brain processes distractions. They found that neural activity and changes to pupil size in response to distractors can predict how well the brain helps focus on a goal.
National Institutes of Health, US Department of Defense

Contact: Karl Bates
karl.bates@duke.edu
919-681-8054
Duke University

Public Release: 4-Feb-2015
PLOS ONE
E-cigarette exposure impairs immune responses in mouse model, new research finds
In a study with mice, Johns Hopkins Bloomberg School of Public Health researchers have found that e-cigarettes compromise the immune system in the lungs and generate some of the same potentially dangerous chemicals found in traditional nicotine cigarettes.
NIH/National Cancer Institute, Flight Attendant Medical Research Institute

Contact: Barbara Benham
bbenham1@jhu.edu
410-614-6029
Johns Hopkins University Bloomberg School of Public Health

Public Release: 4-Feb-2015
New England Journal of Medicine
Paramedics may be first source of treatment for stroke patients, UCLA study finds
In the first study of its kind, a consortium led by UCLA physicians found that paramedics can start medications for patients in the first minutes after onset of a stroke.
NIH/National Institutes of Neurological Disorders and Stroke

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-2262
University of California - Los Angeles Health Sciences

Public Release: 4-Feb-2015
New England Journal of Medicine
Final results of the HIV prevention study VOICE are published in NEJM
Researchers who conducted the VOICE study involving more than 5,000 women in Africa detail in the NEJM how none of the products (tenofovir, Truvada and tenofovir vaginal gel) was effective in preventing HIV and the extent that women did not use them. Tests of blood indicate nonuse began early; many women never used the products. Yet, among women in the tenofovir gel group whose blood tests indicated use, HIV risk was reduced by 66 percent.
NIH/National Institute of Allergy and Infectious Diseases, NIH/Eunice Kennedy Shriver Institute for Child Health and Human Development, NIH/National Institute of Mental Health

Contact: Lisa Rossi
rossil@upmc.edu
Microbicide Trials Network

Public Release: 4-Feb-2015
Science Translational Medicine
Potential pancreatic cancer treatment could increase life expectancy
Pancreatic cancer cells are notorious for being protected by a fortress of tissue, making it difficult to deliver drugs to either shrink the tumor or stop its growth. Now researchers at the University of North Carolina at Chapel Hill have developed a device that could change all that: By using electric fields, the device can drive chemotherapy drugs directly into tumor tissue, preventing their growth and in some cases, shrinking them.
The University Cancer Research Fund, NIH/Pioneer Award, Synecor LLC, and others

Contact: Thania Benios
thania_benios@unc.edu
919-962-8596
University of North Carolina at Chapel Hill

Public Release: 4-Feb-2015
Neuron
Brain marker hints at depression, anxiety years later
A car accident, the loss of a loved one, and financial trouble are just a few of the myriad stressors we may encounter in our lifetimes. How well will we deal with the inevitable lows of life? By looking at an area of the brain called the amygdala, Duke scientists can predict depression or anxiety in response to stressful life events as far as four years in the future.
National Institutes of Health, NIH/National Institute of Child Health and Human Development, Duke University

Contact: Karl Bates
karl.bates@duke.edu
919-681-8054
Duke University

Public Release: 3-Feb-2015
OncoImmunology
Dartmouth researchers reprogram tumor's cells to attack itself
Inserting a specific strain of bacteria into the microenvironment of aggressive ovarian cancer transforms the behavior of tumor cells from suppression to immunostimulation, Dartmouth researchers have found. The findings demonstrate a new approach in immunotherapy that can be applied in a variety of cancer types.
National Institutes of Health, NIH/National Institute of General Medical Sciences

Contact: Kirk Cassels
kirk.A.Cassels@Hitchcock.org
603-653-6177
The Geisel School of Medicine at Dartmouth

Public Release: 3-Feb-2015
Journal of Neuroscience
Researchers identify key mechanisms underlying HIV-associated cognitive disorders
New findings, published today by researchers at the University of California, San Diego School of Medicine, open the door to the development of new therapies to block or decrease cognitive decline due to HIV-associated neurocognitive disorders, estimated to affect 10 to 50 percent of aging HIV sufferers to some degree.
NIH/National Institute of Aging, NIH/National Institute of Mental Health, NIH/National Institute for Neurological Disorders and Stroke

Contact: Bonnie Ward
bjward@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 3-Feb-2015
Review of Economics and Statistics
Choosing a cell phone, prescription drug plan or new car? Read this first
To help people make better choices when confronted by a large number of options, researchers have studied two decision-making strategies that break down the options into smaller groups that can be evaluated more effectively. One approach, analogous to a sports tournament, increased by 50 percent the likelihood that volunteer study subjects would make the best choice.
NIH/National Institute of Aging

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology

Public Release: 3-Feb-2015
Journal of Neuroscience
Superager brains yield new clues to their remarkable memories
'Cognitive SuperAgers,' persons aged 80 and above with extraordinarily sharp memories, have distinctly different looking brains than those of normal older people, according to new research. A Northwestern study begins to reveal why the memories of these cognitively elite elders don't suffer the usual ravages of time. The discoveries may foster the development of strategies to protect the memories of normal aging persons as well as treat dementia.
National Institutes of Health, Davee Foundation

Contact: Marla Paul
marla-paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 3-Feb-2015
Circulation Research
Researchers identify 2 genetic mutations that interact to lower heart attack risk
Researchers have determined that two mutations on a single gene can interact in a way that lowers the carrier's risk for a heart attack.
National Institutes of Health, NIH/National Heart, Lung and Blood Institute, National Institute on Minority Health and Health Disparities

Contact: Wolfgang Sadee
Wolfgang.Sadee@osumc.edu
614-292-1597
Ohio State University

Public Release: 3-Feb-2015
Proceedings of the National Academy of Sciences
MGH/MIT study identifies neurons important for induction of natural REM sleep
An MGH/MIT team has found that that activation of cholinergic neurons -- those that release the neurotransmitter acetylcholine -- in two brain stem structures can induce REM sleep in an animal model. Better understanding of mechanisms that control different sleep states is essential to improved treatment of sleep disorders.
National Institutes of Health

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital

Public Release: 3-Feb-2015
Stem Cell Reports
Glioblastoma: Study ties 3 genes to radiation resistance in recurrent tumors
A new study identifies three genes that together enable a lethal form of brain cancer to recur and progress after radiation therapy. The findings could lead to new therapies for brain tumors that target cancer stem cells.
American Cancer Society, National Institutes of Health, Danish Cancer Society, Danish National Research Foundation

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 3-Feb-2015
Arthritis & Rheumatology
Seeing the knee in a new light: Fluorescent probe tracks osteoarthritis development
A harmless fluorescent probe injected into a joint may make it easier to diagnose and monitor osteoarthritis, leading to better patient care. A new study led by biomedical researchers at Tufts University reports that such a probe successfully tracked the development of early to moderate osteoarthritis in male mice.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH/National Institute of General Medical Sciences, NIH/National Center for Advancing Translational Sciences, National Science Foundation

Contact: Siobhan Gallagher
Siobhan.gallagher@tufts.edu
617-636-6586
Tufts University, Health Sciences Campus

Public Release: 3-Feb-2015
Mayo Clinic Proceedings
Precision medicine in action: Genomic test helps solve medical mystery
Precision medicine is getting a jump-start from a new national initiative announced in President Obama's State of the Union message. One Georgia family has already experienced its benefits: genomic testing called whole exome sequencing helped Mayo Clinic neurologist Zbigniew Wszolek, M.D., solve a medical mystery that had left a boy with painful, jerking spasms that at times prevented him from walking or talking. Dr. Wszolek describes the case in a newly published article in the medical journal Mayo Clinic Proceedings.
Max Kade Foundation, NIH/National Institutes of Neurological Disorders and Stroke

Contact: Kevin Punsky
punsky.kevin@mayo.edu
904-953-0746
Mayo Clinic

Public Release: 3-Feb-2015
Journal of Neuroscience
Cocaine users have impaired ability to predict loss
Cocaine addicted individuals may continue their habit despite unfavorable consequences like imprisonment or loss of relationships because their brain circuits responsible for predicting emotional loss are impaired, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published today in The Journal of Neuroscience.
NIH/National Institute on Drug Abuse, NIH/National Institute on Mental Health

Contact: Sasha Walek
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 3-Feb-2015
JAMA
Just knowing isn't enough: Issuing hospital report cards had no impact on surgery outcomes
If you're an older person having a major operation these days, it is very likely that your hospital is receiving a 'report card' on their performance. These reports are designed to prompt hospitals to improve in areas where they perform poorly. That's the good news. The not-so-good news: Those 'report cards' do not seem to be making things better for patients.
National Institutes of Health

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 3-Feb-2015
Science Signaling
Researchers ID genetic cues for a big heart
An enlarged cardiac muscle can force the heart to work harder to pump blood throughout the body, weakening the organ until it eventually wears out. Duke researchers have uncovered the circuitry of signals that govern the heart's growth in flies, giving insight into a dangerous enlargement of the heart called cardiac hypertrophy that can result from high blood pressure or inherited conditions like Noonan syndrome.
National Institutes of Health

Contact: Karl Bates
karl.bates@duke.edu
919-681-8054
Duke University

Showing releases 251-275 out of 3606.

<< < 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 > >>

     
   

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