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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 276-300 out of 3510.

<< < 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 > >>

Public Release: 25-Sep-2014
Psychosomatic Medicine
Coping techniques help patients with COPD improve mentally, physically
Coaching patients with chronic obstructive pulmonary disease to manage stress, practice relaxation and participate in light exercise can boost a patient's quality of life and can even improve physical symptoms, researchers at Duke Medicine report.
National Institutes of Health

Contact: Samiha Khanna
samiha.khanna@duke.edu
919-419-5069
Duke University Medical Center

Public Release: 25-Sep-2014
Plant Cell
Researchers uncover structure of enzyme that makes plant cellulose
Purdue researchers have discovered the structure of the enzyme that makes cellulose, a finding that could lead to easier ways of breaking down plant materials to make biofuels and other products and materials.
Center for the Direct Catalytic Conversion of Biomass to Biofuels, National Science Foundation, National Institutes of Health, National Research Foundation of Korea

Contact: Natalie van Hoose
nvanhoos@purdue.edu
765-496-2050
Purdue University

Public Release: 25-Sep-2014
Cell
How the ends of chromosomes are maintained for cancer cell immortality
Maintaining telomeres is a requisite feature of cells that are able to continuously divide and also a hallmark of human cancer. Telomeres are much like the plastic cap on the ends of shoelaces -- they keep the ends of DNA from fraying. In a new study published this week in Cell, researchers describe a mechanism for how cancer cells take over one of the processes for telomere maintenance to gain an infinite lifespan.
NIH/National Cancer Institute, NIH/National Institute for General Medical Sciences, Abramson Cancer Research Institute, Basser Research Center for BRCA

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 25-Sep-2014
Cell
Surprising diversity of antibody family provides clues for HIV vaccine design
Scientists at The Scripps Research Institute have described how a single family of antibodies that broadly neutralizes different strains of HIV has evolved remarkably diverse structures to attack a vulnerable site on the virus. The findings provide clues for the design of a future HIV vaccine.
International AIDS Vaccine Initiative Neutralizing Antibody Center, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, HIV Vaccine Research and Design Program, National Institutes of Health

Contact: Madeline McCurry-Schmidt
madms@scripps.edu
858-784-9254
Scripps Research Institute

Public Release: 25-Sep-2014
Cell Reports
NYU Langone scientists identify key factor that maintains stem cell identity
A protein implicated in several cancers appears to play a pivotal role in keeping stem cells in an immature 'pluripotent' state, according to a new study by NYU Langone Medical Center scientists.
New York Stem Cell Foundation, Lady Tata Memorial Trust for Leukemia, American Society of Hematology, Leukemia & Lymphoma Society, NIH/National Cancer Institute, National Institutes of Health

Contact: Jim Mandler
Jim.Mandler@nyumc.org
212-404-3525
NYU Langone Medical Center / New York University School of Medicine

Public Release: 25-Sep-2014
American Journal of Human Genetics
Large study pinpoints synapse genes with major roles in severe childhood epilepsies
An international research team has identified gene mutations causing severe, difficult-to-treat forms of childhood epilepsy. Many of the mutations disrupt functioning in the synapse, the highly dynamic junction at which nerve cells communicate with one another.
National Institutes of Health, European Science Foundation, The Andrew's Foundation

Contact: John Ascenzi
ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia

Public Release: 25-Sep-2014
Cell Reports
New protein players found in key disease-related metabolic pathway
Cells rely on the mechanistic target of rapamycin complex 1 (mTORC1) pathway -- which senses the availability of nutrients -- to coordinate their growth with existing environmental conditions. The lab of Whitehead Member David Sabatini has identified a family of proteins that negatively regulate the branch upstream of mTORC1 that senses amino acids, the building blocks of proteins. The mTORC1 pathway is known to be deregulated in a variety of diseases, including diabetes, epilepsy, and cancer.
National Institutes of Health, Department of Defense

Contact: Nicole Giese Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

Public Release: 25-Sep-2014
Cell Reports
Novel compound prevents metastasis of multiple myeloma in mouse studies
Dana-Farber scientists and colleagues find the compound olaptesed pegol can stop multiple myeloma from spreading in mouse models, potentially leading to a new approach in addressing the challenge of metastasis, one of the deadliest aspects of cancer.
NIH/National Cancer Institue

Contact: Teresa M Herbert
teresa_herbert@dfci.harvard.edu
617-632-5653
Dana-Farber Cancer Institute

Public Release: 25-Sep-2014
Molecular Cell
Super enhancers in the inflamed endothelium
A study led by researchers at Brigham and Women's Hospital and Dana-Farber Cancer Institute is the first to demonstrate that BET bromodomain-containing proteins help execute this global inflammatory program in the endothelium while BET bromodomain inhibition can significantly decrease atherosclerosis in vivo.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-525-6383
Brigham and Women's Hospital

Public Release: 24-Sep-2014
Proceedings of the National Academy of Sciences
First mouse model for ALS dementia
The first animal model for ALS dementia, a form of ALS that also damages the brain, has been developed by Northwestern Medicine scientists. The advance will allow researchers to directly see the brains of living mice, under anesthesia, at the microscopic level. This will accelerate drug testing by allowing direct monitoring of test drugs in real time to determine if they work.
National Institutes of Health

Contact: marla Paul
marla-paul@northwestern.edu
Northwestern University

Public Release: 24-Sep-2014
JAMA
Better information about prenatal testing leads to fewer tests
A clinical trial led by UC San Francisco has found that when pregnant women are educated about their choices on prenatal genetic testing, the number of tests actually drops, even when the tests are offered with no out-of-pocket costs.
National Institutes of Health, March of Dimes Foundation

Contact: Elizabeth Fernandez
elizabeth.fernandez@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 24-Sep-2014
Cognitive and Behavioral Neurology
Alzheimer's patients can still feel the emotion long after the memories have vanished
A new University of Iowa study further supports an inescapable message: caregivers have a profound influence -- good or bad -- on the emotional state of individuals with Alzheimer's disease. Patients may not remember a recent visit by a loved one or having been neglected by staff at a nursing home, but those actions can have a lasting impact on how they feel.
NIH/National Institute of Neurological Disorders and Stroke, National Science Foundation Graduate Research Fellowship, Kiwanis International

Contact: John Riehl
john-riehl@uiowa.edu
319-384-3109
University of Iowa Health Care

Public Release: 24-Sep-2014
Journal of Clinical Oncology
Good news for young patients with a leukemia subtype associated with a poor prognosis
St. Jude Children's Research Hospital investigators found that adjusting treatment based on early response to chemotherapy made a life-saving difference to young patients with an acute lymphoblastic leukemia subtype associated with a poor outcome.
NIH/National Cancer Institute, NAtional Institutes of Health, National Health & Medical Research Council, Australia, Leukemia & Lymphoma Society, Alex's Lemonade Stand Foundation, Stand Up to Cancer, ALSAC

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 24-Sep-2014
UTHealth researchers to assess asthma risk in health care workers
Researchers at The University of Texas Health Science Center at Houston School of Public Health have been awarded a four-year, $1.3 million grant by the Centers for Disease Control and Prevention and the National Institute for Occupational Safety and Health to study how the risk of asthma has changed for health care workers in Texas over the last 10 years.
Centers for Disease Control and Prevention, NIH/National Institute for Occupational Safety and Health

Contact: Hannah Rhodes
Hannah.C.Rasorrhodes@uth.tmc.edu
713-500-3053
University of Texas Health Science Center at Houston

Public Release: 24-Sep-2014
Pitt drug discovery researchers receive $5.8 million federal grant to build 3-D liver model
Researchers at the University of Pittsburgh School of Medicine have been selected by the National Institutes of Health to develop a microfluidic, 3-D human liver model for drug efficacy and toxicity testing as part of the organization's Tissue Chip for Drug Screening program.
National Institutes of Health

Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences

Public Release: 24-Sep-2014
Neurology
Think you have Alzheimer's? You just might be right, study says
New research by scientists at the University of Kentucky's Sanders-Brown Center on Aging suggests that people who notice their memory is slipping may be on to something.
NIH/National Institute on Aging, National Center for Advancing Translational Sciences

Contact: Laura Dawahare
laura.dawahare@uky.edu
859-257-5307
University of Kentucky

Public Release: 24-Sep-2014
Science Translational Medicine
Immune activity shortly after surgery holds big clue to recovery rate, Stanford team finds
The millions of people who undergo major surgery each year have no way of knowing how long it will take them to recover from the operation. Some will feel better within days. For others, it will take a month or more. Right now, doctors can't tell individual patients which category they'll fit into.
Stanford University, California Institute for Regenerative Medicine, European Commission, Food and Drug Administration, Department of Defense, National Institutes of Health

Contact: Bruce Goldman
goldmanb@stanford.edu
650-725-2106
Stanford University Medical Center

Public Release: 24-Sep-2014
Nature
How a single, genetic change causes retinal tumors in young children
David E. Cobrinik, M.D., Ph.D., of The Vision Center at Children's Hospital Los Angeles, together with colleagues at Memorial Sloan-Kettering Cancer Center, has answered the long-standing question of why mutations to the RB1 gene primarily cause tumors of the retina and not of other cell types.
National Institutes of Health

Contact: Debra Kain
dkain@chla.usc.edu
323-361-1812
Children's Hospital Los Angeles

Public Release: 24-Sep-2014
Neurology
Memory slips may signal increased risk of dementia years later
New research suggests that people without dementia who begin reporting memory issues may be more likely to develop dementia later, even if they have no clinical signs of the disease. The study is published in the Sept. 24, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.
National Institutes of Health, NIH/National Institute on Aging, NIH/National Center for Advancing Translational Sciences

Contact: Rachel Seroka
rseroka@aan.com
612-928-6129
American Academy of Neurology

Public Release: 23-Sep-2014
Case Western Reserve University on track to become No. 1 synchrotron lab in world
Case Western Reserve University's synchrotron facility at Brookhaven National Laboratory is on its way to becoming the No. 1 beamline facility for biology in the world by early 2016, thanks to a jumpstart grant of $4.6 million from the National Institute of Biomedical Imaging and Bioengineering, a component of the National Institutes of Health.
NIH/National Institute of Biomedical Imaging and Bioengineering, National Science Foundation, US Department of Energy

Contact: Jeannette Spalding
jeannette.spalding@case.edu
216-368-3004
Case Western Reserve University

Public Release: 23-Sep-2014
OncoImmunology
New anti-cancer peptide vaccines and inhibitors developed by Ohio State Researchers
Researchers have developed two new anticancer peptide vaccines and two peptide inhibitors as part of a larger peptide immunotherapy effort at The Ohio State University Comprehensive Cancer Center. The vaccines and inhibitors are designed to target the HER-3 and IGF-1R receptors, which are over-expressed in cancers of the breast, pancreas, esophagus and colon.
NIH/National Cancer Institute

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 23-Sep-2014
American Journal of Sports Medicine
Does size matter? MRI imaging sheds light on athletes most at risk for severe knee injury
With only 200-300,000 per year, ACL injuries are far less common than ankle ligament injuries, which number more than two million annually. But ACL injuries can end sports careers and are proven to lead to the early onset of osteoarthritis, setting young athletes on a track towards joint replacement beginning as early as their 30s. Two Vermont studies provide greater clues about those most at risk.
National Institutes of Health, US Department of Energy

Contact: Jennifer Nachbur
jennifer.nachbur@uvm.edu
802-656-7875
University of Vermont

Public Release: 23-Sep-2014
UW-Madison team developing 'tissue chip' to screen neurological toxins
A multidisciplinary team at the University of Wisconsin-Madison and the Morgridge Institute for Research is creating a faster, more affordable way to screen for neural toxins, helping flag chemicals that may harm human development.
National Institutes of Health

Contact: James Thomson
jthomson@morgridge.org
608-316-4348
University of Wisconsin-Madison

Public Release: 23-Sep-2014
International Journal of Drug Policy
NYU-Mount Sinai Beth Israel study explores drug users' opinions on genetic testing
The study gauged drug users' attitudes and understandings of genetics and genetic testing through six focus groups segregated by race and ethnicity to increase participants' comfort in talking about racial and ethnic issues.
National Institutes of Health

Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University

Public Release: 23-Sep-2014
Alcoholism: Clinical & Experimental Research
Research shows alcohol consumption influenced by genes
How people perceive and taste alcohol depends on genetic factors, and that influences whether they 'like' and consume alcoholic beverages, according to researchers in Penn State's College of Agricultural Sciences.
National Institutes of Health

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State

Showing releases 276-300 out of 3510.

<< < 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 > >>

     
   

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