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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 276-300 out of 3722.

<< < 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 > >>

Public Release: 4-May-2015
Proceedings of the National Academy of Sciences
Study IDs collagen-damaging protein in White Nose syndrome
In the Proceedings of the National Academy of Sciences, researchers from Brown University and the University of California at San Francisco identify an enzyme that may damage bats in the fungal disease White Nose syndrome. In lab experiments, they uncovered an inhibitor that could limit the ability of the fungal species to destroy collagen.
Sandler Foundation, Burroughs Wellcome Fund, National Institutes of Health

Contact: David Orenstein
Brown University

Public Release: 4-May-2015
Journal of Clinical Investigation
How oxidizing a heart 'brake' causes heart damage
Oxidative stress has been long known to fuel disease, but how exactly it damages various organs has been challenging to sort out. Now scientists from Johns Hopkins say research in mice reveals why oxidation comes to be so corrosive to heart muscle.
Fondation Leducq Transatlantic Networks of Excellence, Abraham and Virginia Weiss and Michael and Janet Huff Endowments, NIH/National Heart, Lung and Blood Institute, American Heart Association, Japan Heart Founda­tion, Sarnoff Foundation

Contact: Ekaterina Pesheva
Johns Hopkins Medicine

Public Release: 4-May-2015
2015 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO)
American Journal of Ophthalmology
Patients with AIDS at increased risk of developing age-related macular degeneration
Patients with acquired immunodeficiency syndrome have a four-fold increase in their risk of developing intermediate-stage age-related macular degeneration compared to people of the same age who are not infected with HIV, according to results from the Longitudinal Study of the Ocular Complications of AIDS presented today at the 2015 ARVO Annual Meeting in Denver, Colo.
NIH/National Eye Institute

Contact: Jessica Mikulski
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 4-May-2015
Proceedings of the National Academy of Sciences
Researchers 'un-can' the HIV virus
If the human immunodeficiency virus (HIV) is a bit like a hermetically sealed tin can no one has yet been able to break open, the good news is that researchers at the CHUM Research Centre, affiliated with the University of Montreal, have identified a way to use a 'can opener' to force the virus to open up and to expose its vulnerable parts, allowing the immune system cells to then kill the infected cells.
Canadian Institutes of Health Research, Canada Foundation for Innovation, Fonds de recherche du Québec - Santé, Canada Research Chairs, Center for HIV/AIDS Vaccine Immunology Discovery, National Institutes of Health

Contact: William Raillant-Clark
University of Montreal

Public Release: 4-May-2015
New study suggests prominent role for pharmacies in reducing asthma-related illness
A new study shows how pharmacies might collaborate with physicians and families to reduce asthma-related illness. The Cincinnati Children's study found that pharmacies in neighborhoods with high rates of asthma-related emergency-room use and hospitalization filled fewer asthma controller medications compared to asthma rescue medications.
National Institutes of Health

Contact: Jim Feuer
Cincinnati Children's Hospital Medical Center

Public Release: 4-May-2015
Duke study uncovers foundations of heart regeneration
Duke researchers have found that a key to the zebrafish's ability to regenerate cardiac tissue lies in the outer layer of the heart known as the epicardium. When this critical layer is damaged, the whole repair process is delayed as the epicardium undergoes a round of self-healing before tending to the rest of the heart. The finding points to a possible target for repairing the damage caused by a heart attack.
American Heart Association, National Institutes of Health, American Federation for Aging Research

Contact: Karl Bates
Duke University

Public Release: 3-May-2015
Genes & Development
Study shows where damaged DNA goes for repair
New research sheds light on the process of DNA repair in the cell. Expanded repeats of the CAG/CTG trinucleotide in yeast shift to the periphery of the cell nucleus for repair. This shift is important for preventing repeat instability and genetic disease. Going out to the 'repair shop' at the nuclear periphery is a previously unrecognized yet important step to maintain repetitive DNA and to prevent damage to chromosomes.
National Institutes of Health, Tufts University, Swiss National Science Foundation, Human Frontiers Science Program

Contact: Kim Thurler
Tufts University

Public Release: 3-May-2015
2015 Association for Reseach in Vision and Ophthalmology annual meeting
New England Journal of Medicine
Gene therapy efficacy for LCA: Improvement is followed by decline in vision
Gene therapy for Leber congenital amaurosis, an inherited disorder that causes loss of night- and day-vision starting in childhood, improved patients' eyesight within weeks of treatment in a clinical trial of 15 children and adults at the Scheie Eye Institute at the Perelman School of Medicine at the University of Pennsylvania. New results involving a subset of patients from the ongoing trial show these benefits peaked one to three years after treatment, then diminished.
NIH/National Eye Institute

Contact: Lee-Ann Donegan
University of Pennsylvania School of Medicine

Public Release: 1-May-2015
Plant Breeding
Low-allergen soybean could have high impact
Scientists from the UA and University of Illinois have created a new variety of low-allergenic soybean. The new crop could have a major impact on the production of baby formula, processed foods and livestock feed.
Illinois-Missouri Biotechnology Alliance, Illinois Agricultural Experiment Station, National Institutes of Health, Southwest Environmental Health Sciences Center, BIO5 Institute of the University of Arizona, USDA/NIFA, and others

Contact: Daniel Stolte
University of Arizona

Public Release: 1-May-2015
Parent training reduces serious behavioral problems in children with autism
Young children with autism spectrum disorder, who also have serious behavioral problems, showed improved behavior when their parents were trained with specific, structured strategies to manage tantrums, aggression, self-injury, and non-compliance. The findings from this parent training study by Yale and Emory University researchers were published recently in the Journal of the American Medical Association.
NIH/National Institute of Mental Health, NIH/National Center for Advancing Translational Sciences, Marcus Foundation, Joseph B. Whitehead Foundation, and others

Contact: Karen N. Peart
Yale University

Public Release: 1-May-2015
Taking a vacation from diabetes: Teens take 'artificial pancreas' for a test run
This weekend a group of teenagers will test an 'artificial pancreas' in a real-world environment. Although Yale has been studying these devices for the last decade, this is the first time one will be tested in pediatric patients here outside the hospital.
Juvenile Diabetes Research Foundation, Yale Clinical, NIH/National Center for Advancing Translational Sciences

Contact: Karen N. Peart
Yale University

Public Release: 1-May-2015
Journal of Pediatrics
Mixing energy drinks, alcohol tied to abusive drinking in teens
Researchers from Dartmouth's Norris Cotton Cancer Center found teens aged 15-17 years old who had ever mixed alcohol with energy drinks were four times more likely to meet the criteria for alcohol use disorder than a teen who has tried alcohol but never mixed it with an energy drink.
National Institutes of Health

Contact: Kirk Cassels
The Geisel School of Medicine at Dartmouth

Public Release: 1-May-2015
Patients with gastrointestinal tumors at higher risk of other cancers
Researchers at UC San Diego School of Medicine conducted the first population-based study that characterizes the association and temporal relationship between gastrointestinal stromal tumors (GIST) and other cancers. The results, published by Cancer on April 30, indicate that one in 5.8 patients with GIST will develop additional malignancies before and after their diagnosis.
National Institutes of Health, GIST Research Fund, UC San Diego Academic Senate Health Sciences Research Grant

Contact: Yadira Galindo
University of California - San Diego

Public Release: 1-May-2015
Proceedings of the National Academy of Sciences
How to reset a diseased cell
In proof-of-concept experiments, researchers at University of California, San Diego School of Medicine demonstrate the ability to tune medically relevant cell behaviors by manipulating a key hub in cell communication networks. The manipulation of this communication node, reported in this week's issue of Proceedings of the National Academy of Sciences, makes it possible to reprogram large parts of a cell's signaling network instead of targeting only a single receptor or cell signaling pathway.
National Institutes of Health, American Cancer Society, Burroughs Wellcome Fund, Dorris Duke Charitable Foundation, American Heart Association

Contact: Scott LaFee
University of California - San Diego

Public Release: 1-May-2015
Cell Reports
A feel for flight: How bats are teaching scientists to build better aircraft
Researchers have studied how bats can sense their environment using neural cells connected to their wings. This makes them amazing flyers, able to adapt to a variety of challenging situations. By understanding the neuroscience of bat flight, scientists are also learning how to design smarter and better planes.
National Institutes of Health

Contact: Lucky Tran
Columbia University Medical Center

Public Release: 1-May-2015
Journal of Aging Research
Majority of older adults willing to be screened by telephone for dementia
Nearly two-thirds of older adults were willing to undergo telephone screening for dementia, according to a new study from the Indiana University Center for Aging Research and the Regenstrief Institute. Willingness to be screened by phone did not differ by sex, age or race.
NIH/National Institute on Aging

Contact: Cindy Fox Aisen
Indiana University

Public Release: 1-May-2015
Genes & Development
UNC researchers create DNA repair map of the entire human genome
When common chemotherapy drugs hit cancer cells, they damage DNA so that the cells can't replicate. But the cells have ways to repair the DNA, and the drugs aren't effective enough. UNC researchers created a way to find where this DNA repair happens throughout all of human DNA. The finding offers scientists a route to target the proteins cancer cells use to circumnavigate therapy. The benefit could be more effective and better cancer therapeutics.
National Institutes of Health

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 1-May-2015
Rochester team receives NEI grant for restoring vision through retinal regeneration
A team of researchers at the University of Rochester is designing an optical system to image responses to light of large numbers of individual cells in the retina, with the objective of accelerating the development of the next generation of cures for blindness. The Rochester team and their partners will receive $3.8 million from the National Eye Institute over the next five years.
NIH/National Eye Institute

Contact: Leonor Sierra
University of Rochester

Public Release: 1-May-2015
Imaging the windows to the soul: Eye researchers pursue 'audacious' goal
The Medical College of Wisconsin's Advanced Ocular Imaging Program has received a $4.4 million, five-year grant from the National Institutes of Health's National Eye Institute (NEI) to participate in the NEI's 'Audacious Goals Initiative.' The initiative seeks to push the boundaries of vision science with the goal of regenerating neurons and neural connections in the eye.
National Institutes of Health

Contact: Maureen Mack
Medical College of Wisconsin

Public Release: 30-Apr-2015
Large new study of phthalate exposure and breast cancer risk
Epidemiologist Katherine Reeves at UMass Amherst is leading the largest study to date investigating a possible relationship between phthalate exposure and breast cancer risk with a three-year, $1.5 million grant from NIEHS. She and colleagues will study phthalate metabolites. Only a handful of small studies have looked at whether phthalates affect human breast cancer risk and none has measured phthalate metabolites before a cancer diagnosis.
NIH/National Institute of Environmental Health Sciences

Contact: Janet Lathrop
University of Massachusetts at Amherst

Public Release: 30-Apr-2015
New origin theory for cells that gave rise to vertebrates
Zebras' vivid pigmentation and the fight or flight instinct. These and other features of the world's vertebrates stem from neural crest cells, but little is known about their origin. Northwestern University scientists propose a new model for how neural crest cells, and thus vertebrates, arose more than 500 million years ago. They report that these cells retain the molecular underpinnings that control pluripotency -- the ability to give rise to all the cell types that make up the body.
National Institutes of Health

Contact: Megan Fellman
Northwestern University

Public Release: 30-Apr-2015
Texas Biomed receives NIH grant to study papillomavirus-based AIDS vaccine
Scientists at Texas Biomedical Research Institute have begun work on a study to create an attenuated, or weakened, virus that is a hybrid of the papilloma virus and the human immunodeficiency virus, with the potential to jumpstart a body's immune response to develop antibodies against both viruses.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Lisa Cruz
Texas Biomedical Research Institute

Public Release: 30-Apr-2015
Journal of Biological Chemistry
Moffitt researchers discover new mechanism controlling cell response to DNA damage
DNA can be damaged by different environmental insults, such as ultraviolet light, ionizing radiation, oxidative stress or certain drugs. If the DNA is not repaired, cells may begin growing uncontrollably, leading to the development of cancer. Therefore, cells must maintain an intricate regulatory network to ensure that their DNA remains intact. Moffitt Cancer Center researchers have discovered a novel mechanism that controls a cell's response to DNA damage.
National Institutes of Health, James & Esther King Biomedical Research Program

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 30-Apr-2015
Proceedings of the National Academy of Sciences
Compact synchrotron makes tumors visible
Soft tissue disorders like tumors are very difficult to recognize using normal X-ray machines. There is hardly any distinction between healthy tissue and tumors. Researchers at the Technische Universität München have now developed a technology using a compact synchrotron source that measures not only X-ray absorption, but also phase shifts and scattering. Tissue that is hardly recognizable using traditional X-ray machines is now visible.
German Research Foundation/Cluster of Excellence Munich-Centre for Advanced Photonics, European Research Council, NIH/National Institute of General Medical Sciences, National Center for Research Resources, Helmholz Center NanoMikro, and others

Contact: Dr. Andreas Battenberg
Technische Universitaet Muenchen

Public Release: 30-Apr-2015
Light -- not pain-killing drugs -- used to activate brain's opioid receptors
Washington University School of Medicine neuroscientists have attached the light-sensing protein rhodopsin to opioid receptor parts to activate the receptor pathways using light from a laser fiber-optic device. They also influenced the behavior of mice using light, rather than drugs, to activate the reward response.
NIH/National Institute on Drug Abuse, NIH/National Institute of Mental Health, NIH/National Institute of General Medical Sciences

Contact: Jim Dryden
Washington University School of Medicine

Showing releases 276-300 out of 3722.

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