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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 276-300 out of 3748.

<< < 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 > >>

Public Release: 4-Jun-2015
Proceedings of the Royal Society B
Study links delay of gratification to how brain structures are connected
The ability to delay gratification in chimpanzees is linked to how specific structures of the brain are connected and communicate with each other, according to researchers at Georgia State University and Kennesaw State University.
National Institutes of Health

Contact: LaTina Emerson
Georgia State University

Public Release: 4-Jun-2015
Cancer Discovery
An immune system marker for therapy-resistant prostate cancer
A team at CSHL shows how signaling by an immune system component called interleukin-6 (IL-6) appears to play an important role in driving aggressive, therapy-resistant prostate cancer. 'We are hopeful that translating the IL-6 discovery into the clinics could help us stratify patients into good responders and bad responders. For any hospital this would be a major breakthrough,' says PI Dr. Lloyd Trotman.
Pershing Square Sohn Cancer Research Alliance, American Cancer Society, National Institutes of Health, US Department of Defense, STARR Foundation

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 4-Jun-2015
SLEEP 2015
Eating less during late night hours may stave off some effects of sleep deprivation
Eating less late at night may help curb the concentration and alertness deficits that accompany sleep deprivation, according to results of a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania that will be presented at SLEEP 2015, the 29th annual meeting of the Associated Professional Sleep Societies LLC.
National Institutes of Health, Clinical Translational Research Center at Penn, Department of the Navy, Office of Naval Research

Contact: Greg Richter
University of Pennsylvania School of Medicine

Public Release: 4-Jun-2015
Frontiers in Human Neuroscience
Despite abnormalities after concussion, sleep continues to aid memory and recall
After a concussion, a person can be left with disturbed sleep, memory deficits and other cognitive problems for years, but a new study led by Rebecca Spencer at the University of Massachusetts Amherst suggests that despite these abnormalities, sleep still helps them to overcome memory deficits, and the benefit is equivalent to that seen in individuals without a history of mild traumatic brain injury, also known as concussion.
UMass Amherst's Commonwealth Honors College, National Institutes of Health

Contact: Janet Lathrop
University of Massachusetts at Amherst

Public Release: 4-Jun-2015
How dividing cells end up the same size
A new study from Duke University shows that how much a cell grows before it splits into two depends on its initial size. The finding goes against recent publications suggesting cells always add the same amount of mass, with some random fluctuations, before beginning division.
National Science Foundation, National Institutes of Health, DuPont, David and Lucile Packard Foundation, Defense Advanced Research Projects Agency, Burroughs Wellcome Fund

Contact: Ken Kingery
Duke University

Public Release: 4-Jun-2015
SLEEP 2015
Penn study maps the types of physical activity associated with better sleep
Physical activities, such as walking, as well as aerobics/calisthenics, running, weight-lifting, and yoga/Pilates are associated with better sleep habits, compared to no activity, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania. In contrast, the study shows that other types of physical activity -- such as household and childcare -- work are associated with increased cases of poor sleep habits.
National Institutes of Health

Contact: Greg Richter
University of Pennsylvania School of Medicine

Public Release: 4-Jun-2015
PLOS Pathogens
Shh! Don't wake the sleeping virus!
Scientists at Bar-Ilan University report on a novel experimental model that, for the first time, successfully mimics the 'sleeping' and 'waking' of the varicella-zoster virus. Based on neurons generated from human embryonic stem cells, and not requiring the use of experimental animals, the model allows scientists to test drugs and develop therapies to prevent shingles. It may also contribute to the fight against other viruses -- such as herpes and polio -- that target the human nervous system.
National Institutes of Health, Israel Academy of Sciences, US-Israel Binational Science Foundation

Contact: Elana Oberlander
Bar-Ilan University

Public Release: 4-Jun-2015
Molecular Cell
New tool brings standards to epigenetic studies
Scientists from the University of Chicago have developed a new technique that calibrates a commonly-used tool in epigenetic experiments with an internal standard. The method, ICeChIP, enables greater accuracy and reproducibility, better quality control and unbiased comparisons between experiments - which dramatically improves the accuracy of epigenetic studies and the development of therapeutics against diseases linked to epigenetic changes.
National Institutes of Health, Chicago Biotechnology Consortium, Ellison Foundation

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 4-Jun-2015
Archives of Women's Mental Health
Eating the placenta: trendy but no proven health benefits and unknown risks
Celebrities have spiked women's interest in eating their placentas after childbirth. The practice supposedly protects against postpartum depression, reduces post-delivery pain, boosts energy and helps with lactation among other benefits. But a new review of research on placentophagy did not turn up any human or animal data to support the claims. More concerning, there are no studies examining the risk of ingesting the placenta, which absorbs and protects the fetus from toxins and pollutants.
National Institutes of Health

Contact: Marla Paul
Northwestern University

Public Release: 4-Jun-2015
Arthritis Care & Research
Poor sleep, negative attitude amplify pain in knee osteoarthritis
A new study reports that patients with knee osteoarthritis (OA) who have poor sleep habits display greater central sensitization -- an amplification of clinical pain. Findings published in Arthritis Care & Research, a journal of the American College of Rheumatology, further show OA patients who catastrophize -- consumed by thoughts of pain -- had increased central sensitization that was associated with greater clinical pain.
NIH/National Institutes of Arthritis and Musculoskeletal and Skin Disease, National Institutes of Health

Contact: Dawn Peters

Public Release: 4-Jun-2015
Protein maintains double duty as key cog in body clock and metabolic control
Rev-erbα is a well-studied transcription factor that regulates a cell's internal clock and metabolic genes. In a new study, researchers describe how Rev-erbα regulates the clock in most cells in the body and metabolic genes in the liver, the body's key organ for metabolism of fat as well as sugar. This work has implications for combating the growing epidemic of metabolic disease.
NIH/National Institutes of Diabetes, Digestive, and Kidney Diseases, Cox Medical Research Institute

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 4-Jun-2015
VirScan reveals viral history in a drop of blood
From a single drop of blood, researchers can now simultaneously test for more than 1,000 different strains of viruses that currently or have previously infected a person. Using a new method known as VirScan, researchers from Brigham and Women's Hospital and Harvard Medical School tested for evidence of past viral infections, detecting on average 10 viral species per person. The team reports its findings in Science on June 5.
National Institutes of Health, International AIDS Vaccine Initiative, African Research Chairs Initiative

Contact: Haley Bridger
Brigham and Women's Hospital

Public Release: 4-Jun-2015
TSRI study: Hormone 'erases' male smell for female mice
Scientists at the Scripps Research Institute have found that state-specific odor 'blindness' exists in female mice. Their research shows that female mice cannot sense the odor of male mice when they are in diestrus, the period of sexual inactivity during the reproductive cycle, a lack of sensation directly affecting mouse behavior. The findings point to new avenues for studying senses and behavior.
National Institutes of Health, Ellison Medical Foundation, Wellcome Trust

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 4-Jun-2015
Current Biology
Forks colliding: How DNA breaks during re-replication
Leveraging a novel system designed to examine the double-strand DNA breaks that occur as a consequence of gene amplification during DNA replication, Whitehead Institute scientists are bringing new clarity to the causes of such genomic damage. Moreover, because errors arising during DNA replication and gene amplification result in chromosomal abnormalities often found in malignant cells, these new findings may bolster our understandings of certain drivers of cancer progression.
National Institutes of Health, MIT School of Science Fellowship in Cancer Research

Contact: Matt Fearer
Whitehead Institute for Biomedical Research

Public Release: 4-Jun-2015
PLOS Computational Biology
Planarian regeneration model discovered by artificial intelligence
An artificial intelligence system has for the first time reverse-engineered the regeneration mechanism of planaria -- the small worms whose power to regrow body parts makes them a research model in human regenerative medicine. The discovery presents the first model of regeneration discovered by a non-human intelligence and the first comprehensive model of planarian regeneration, which has eluded human scientists for a century.
National Science Foundation, National Institutes of Health, United States Army Medical Research and Materiel Command, Mathers Foundation

Contact: Kim Thurler
Tufts University

Public Release: 3-Jun-2015
Journal of Experimental Medicine
Penn researchers home in on what's wearing out T cells
When the T cells of your immune system are forced to deal over time with cancer or a chronic infection they become exhausted -- less effective at attacking and destroying invaders. While the PD-1 protein pathway has long been implicated as a primary player in T cell exhaustion, a major question has been whether PD-1 actually directly causes exhaustion. A new paper seems to, at least partially, let PD-1 off the hook.
Robertson Foundation/Cancer Research Institute and the National Institutes of Health

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 3-Jun-2015
Women & Infants receives $5 million grant from NIH
Women & Infants Hospital of Rhode Island has recently received a nearly $5 million grant from the National Institutes of Health to support an Institutional Development Award for their Center of Biomedical Research Excellence (COBRE) for Perinatal Biology. Of the more than 100 COBREs across the country, Women & Infants is the only one specifically focused on developmental research.
National Institutes of Health

Contact: Amy Blustein
Care New England

Public Release: 3-Jun-2015
2015 ASCO Annual Conference
Study supports IDH gene as prognostic marker in anaplastic astrocytoma
A new study suggests that the mutation status of a gene called IDH1 might have prognostic value for anaplastic astrocytomas, and that it may be worth exploring further whether IDH1 status can predict the best chemotherapy for these patients.
NIH/National Cancer Institute

Contact: Darrell E. Ward
Ohio State University Wexner Medical Center

Public Release: 3-Jun-2015
Science Translational Medicine
Scientist at LIMR leads study demonstrating drug-induced tissue regeneration
a study led by Ellen Heber-Katz, Ph.D., of the Lankenau Institute for Medical Research, part of Main Line Health, shows that a primordial form of energy production that still exists in mammals can be harnessed to achieve spontaneous tissue regeneration in mice, without the need for added stem cells.
National Institutes of Health

Contact: Bridget Therriault
Main Line Health, Lankenau Institute for Medical Research

Public Release: 3-Jun-2015
Scientific Reports
Intravenous nutrition source could reduce side effects of chemotherapy
A single dose of an FDA-approved intravenous nutrition source may be able to significantly reduce the toxicity and increase the bioavailability of platinum-based cancer drugs, according to a study by Carnegie Mellon University biologists published in Scientific Reports.
National Institutes of Health, Carnegie Mellon University's Disruptive Health Technology Institute

Contact: Jocelyn Duffy
Carnegie Mellon University

Public Release: 3-Jun-2015
New England Journal of Medicine
Years of good blood sugar control helps diabetic hearts, study finds
Day in and day out, millions of people with diabetes test their blood sugar levels. And many may wonder if all the careful eating, exercise and medication it takes to keep those levels under control is really worth it. A major new study should encourage them to keep going, to protect their hearts from diabetes-related damage. But it should also prompt them to work with their doctors on other ways to reduce their cardiovascular risk.
VA Cooperative Studies Program, National Institutes of Health, Information Resource Center of VA Health Services Research and Development

Contact: Kara Gavin
University of Michigan Health System

Public Release: 3-Jun-2015
Human Brain Mapping
MRI technology reveals deep brain pathways in unprecedented detail
Scientists at Duke Medicine have produced a 3-D map of the human brain stem at an unprecedented level of detail using MRI technology. In a study to be published June 3 in Human Brain Mapping, the researchers unveil an ultra high-resolution brain stem model that could better guide brain surgeons treating conditions such as tremors and Parkinson's disease with deep brain stimulation.
National Institutes of Health, NIH/National Institute of Biomedical Imaging and Bioengineering

Contact: Samiha Khanna
Duke University Medical Center

Public Release: 3-Jun-2015
Environmental Health Perspectives
Air pollution below EPA standards linked with higher death rates
A Harvard T.H. Chan School of Public Health study found death rates among people over 65 are higher in zip codes with more fine particulate air pollution (PM2.5) than in those with lower levels. It is the first study to examine the effect of soot particles in the air in the entire population of a region.
NIH/National Institute of Environmental Health Sciences, US Environmental Protection Agency

Contact: Todd Datz
Harvard School of Public Health

Public Release: 3-Jun-2015
BPA can adversely affect parenting behavior in mice
Biparental care of offspring occurs in only a minority of species. Studies have shown that maternal care can be negatively affected when females are exposed to BPA; however, no studies have shown how this chemical can affect maternal and paternal care. Researchers at the University of Missouri have used biparental California mice to prove that offspring born to parents who are exposed to BPA receive decreased parental care by both the mother and father.
National Institutes of Health

Contact: Jesslyn Chew
University of Missouri-Columbia

Public Release: 3-Jun-2015
Long-term memory formation
A team of NYU neuroscientists has determined how a pair of growth factor molecules contributes to long-term memory formation.
NIH/National Institute of Mental Health

Contact: James Devitt
New York University

Showing releases 276-300 out of 3748.

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