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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 276-300 out of 3680.

<< < 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 > >>

Public Release: 3-Apr-2015
PLOS ONE
UCLA research links HIV to age-accelerating cellular changes
People undergoing treatment for HIV-1 have an increased risk for earlier onset of age-related illnesses such as some cancers, renal and kidney disease, frailty, osteoporosis and neurocognitive disease. But is it because of the virus that causes AIDS or the treatment? New research suggests that HIV itself accelerates these aging related changes by more than 14 years.
NIH/National Institute on Aging grant, UCLA AIDS Institute/CFAR seed grant from the National Institutes of Health, NIH T032 training grant, National Science Foundation grant

Contact: Enrique Rivero
erivero@mednet.ucla.edu
310-794-2273
University of California - Los Angeles Health Sciences

Public Release: 3-Apr-2015
Science Advances
Targeting dangerous inflammation inside artery plaque
A research team showed that a nanotherapeutic medicine can halt the growth of artery plaque cells resulting in the fast reduction of the inflammation that may cause a heart attack.
NIH/National Heart, Lung, and Blood Institute, NIH/Program of Excellence in Nanotechnology Award, National Institutes of Health,Harold S. Geneen Charitable Trust Award, and others

Contact: Lauren Woods
lauren.woods@mountsinai.org
646-634-0869
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 3-Apr-2015
American Journal of Human Genetics
New genetic clues emerge on origin of Hirschsprung's disease
Genetic studies in humans, zebrafish and mice have revealed how two different types of genetic variations team up to cause a rare condition called Hirschsprung's disease. The findings add to an increasingly clear picture of how flaws in early nerve development lead to poor colon function, which must often be surgically corrected. The study also provides a window into normal nerve development and the genes that direct it.
NIH/National Institute of Child Health and Human Development, NIH/National Institute for General Medical Sciences, National Natural Science Foundation of China, Beijing Natural Science Foundation, Beijing Excellent Scientist Fund, and others

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Public Release: 3-Apr-2015
Case Western Reserve to lead international research on resistance to bacteria causing TB
After discovering a unique group of people resistant to tuberculosis (TB) infection, Case Western Reserve researchers are leading an international team dedicated to understanding exactly how they fight off a disease that claims 1.5 million lives each year. The team's goal is to use lessons learned from these resistant individuals to develop an approach to treating and curing TB that is unlike any existing medication.
National Institutes of Health, Bill & Melinda Gates Foundation

Contact: Jeannette Spalding
jeannette.spalding@case.edu
216-368-3004
Case Western Reserve University

Public Release: 3-Apr-2015
Science Advances
CRISPR-Cas editing of C. albicans holds promise for overcoming deadly fungal infections
Candida albicans is a human pathogen that causes potentially lethal infections in immunocompromised individuals. Efforts to overcome Candida's innate resistance to many drugs have been thwarted by an absence of tools enabling genetic modifications. Now, using a modified CRISPR-Cas system, Whitehead Institute researchers can edit the fungus's genome systematically -- an approach that could help scientists understand Candida's unique biology and identify potential drug targets.
National Institutes of Health

Contact: Nicole Giese Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

Public Release: 3-Apr-2015
PLOS Pathogens
Rice can borrow stronger immunity from other plant species, study shows
Rice, one of the world's main staple foods, can boost its built-in immunity against invading disease-causing microbes when immune receptor genes are transferred via genetic engineering from a totally different plant group, this new study shows.
European Molecular Biology Organization, Human Frontier Science Program Organization of France, Gatsby Charitable Foundation in London, US Department of Energy, and National Institutes of Health

Contact: Patricia Bailey
pjbailey@ucdavis.edu
530-756-7127
University of California - Davis

Public Release: 2-Apr-2015
Journal of the National Cancer Institute
Mayo Clinic researchers combine common genetic variants to improve breast cancer
Recent large-scale genomic analyses have uncovered dozens of common genetic variants that are associated with breast cancer. Each variant, however, contributes only a tiny amount to a person's overall risk of developing the disease.
NIH/National Cancer Institute, Breast Cancer Research Foundation

Contact: Joe Dangor
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

Public Release: 2-Apr-2015
Genes & Development
Cancer genes turned off in deadly brain cancer
Scientists have identified a small RNA molecule that can suppress cancer-causing genes in mice with glioblastoma mulitforme, a deadly and incurable type of brain tumor. While standard chemotherapy drugs damage DNA to stop cancer cells from reproducing, the new method stops the source that creates those cancer cells. The approach could also potentially be used for gene silencing in other cancers and diseases of genetic origin.
National Institutes of Health

Contact: Marla Paul
marla-paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 2-Apr-2015
Could a tiny particle stem the plague of citrus greening?
A $4.6 million USDA grant will fund field trials of Zinkicide, a nanoparticle designed to be small enough to move within a citrus trees' stems, leaves, trunk and roots. If successful, it could halt the spread of citrus greening that's devastated citrus industry in Florida and is spreading in other citrus-producing states including California and Texas, as well as other nations.
US Department of Agriculture, NIH/National Institute of Food and Agriculture

Contact: Mark Schlueb
mark.schlueb@ucf.edu
407-823-0221
University of Central Florida

Public Release: 2-Apr-2015
Molecular Cell
USC Norris study finds herpesvirus activates RIG-I receptor to evade body's immune system
Using herpesvirus, molecular immunologists from the University of Southern California Norris Comprehensive Cancer Center have discovered a cellular process that activates a critical immune defense against pathogens, which could have implications for developing drugs to bolster one's immunity to infection. Some herpesvirus infections lead to cancer.
National Institutes of Health, American Cancer Society, USC Norris Comprehensive Cancer Center

Contact: Alison Trinidad
alison.trinidad@usc.edu
323-442-3941
University of Southern California - Health Sciences

Public Release: 2-Apr-2015
AIDS and Behavior
NYU researchers dramatically improve ART adherence for minority PHLA
The intervention was found to be feasible and acceptable. Eight months post-baseline, intervention participants tended to be more likely to evidence 'good' adherence and also had lower HIV viral load levels. Thus the intervention components were highly promising, and merit further study with this vulnerable population.
NIH/National Institutes of Mental Health, Center for Drug Use and HIV Research

Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University

Public Release: 2-Apr-2015
Journal of Exposure Science and Environmental Epidemiology
Placenta reflects arsenic exposure in pregnant women and fetuses, Dartmouth study shows
The placenta can be used to reliably measure arsenic exposure in pregnant women and how much of the toxic metal is transferred to their fetuses, a Dartmouth College study shows in the largest ever analysis of household drinking water arsenic and the mother-to-fetus connection.
NIH/National Institute of Environmental Health, Environmental Protection Agency

Contact: John Cramer
john.cramer@dartmouth.edu
603-646-9130
Dartmouth College

Public Release: 2-Apr-2015
American Naturalist
Being born in lean times is bad news for baboons
The saying 'what doesn't kill you makes you stronger' may not hold up to scientific scrutiny. Baboons born in times of famine are more vulnerable to food shortages later in life, finds a new study. The findings are important because they help explain why people who are malnourished in early childhood often experience poor health as adults.
National Science Foundation, NIH/National Institute on Aging, Duke University, Princeton University, Max Planck Institute for Demographic Research

Contact: Robin Ann Smith
ras10@duke.edu
919-681-8057
Duke University

Public Release: 2-Apr-2015
Proceedings of the National Academy of Sciences
Deconstructing brain systems involved in memory and spatial skills
In work that reconciles two competing views of brain structures involved in memory and spatial perception, researchers at University of California, San Diego School of Medicine have conducted experiments that suggest the hippocampus -- a small region in the brain's limbic system -- is dedicated largely to memory formation and not to spatial skills, such as navigation. The study is published in this week's issue of the Proceedings of the National Academy of Sciences.
US Department of Veterans Affairs, National Science Foundation, NIH/National Institute of Mental Health

Contact: Christina Johnson
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 2-Apr-2015
Journal of Biological Chemistry
Small RNA plays big role suppressing cancer
Researchers at UC Davis have unraveled some of these relationships, identifying several interactions that directly impact liver and colon cancer.
National Institutes of Health

Contact: Dorsey Griffith
dgriffith@ucdavis.edu
916-734-9118
University of California - Davis Health System

Public Release: 2-Apr-2015
Anesthesia & Analgesia
WebTIPS helps make surgery less scary for children -- and their parents
A newly developed website provides parents and children with individualized information and support -- based on factors like coping style and levels of worry and fear -- to help lower anxiety before outpatient surgery in children, according to a pair of articles in the April issue of Anesthesia & Analgesia.
National Institutes of Health

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine

Public Release: 2-Apr-2015
Neurobiology of Disease
Adolescent drinking affects adult behavior through long-lasting changes in genes
Binge-drinking during adolescence may perturb brain development at a critical time and leave lasting effects on genes and behavior that persist into adulthood. The findings, by researchers at the University of Illinois at Chicago College of Medicine using an animal model, are reported online in the journal Neurobiology of Disease.
NIH/National Institute on Alcohol Abuse and Alcoholism, US Department of Veterans Affairs

Contact: Sharon Parmet
sparmet@uic.edu
312-413-2695
University of Illinois at Chicago

Public Release: 2-Apr-2015
Scientists win $3.3 million grant to speed development of treatments for autism, epilepsy
Scientists from the Florida campus of the Scripps Research Institute have been awarded $3.3 million by the National Institutes of Health to identify biomarkers to accelerate drug development for disorders including autism spectrum disorder, epilepsy and some types of intellectual disability.
NIH/National Institute of Mental Health

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 2-Apr-2015
Cellular and Molecular Gastroenterology and Hepatology
Liver injury in NASH leads to a leaky gut
Non-alcoholic steatohepatitis (NASH), the more severe form of non-alcoholic fatty liver disease that can progress to liver fibrosis and cirrhosis, is associated with leakiness of the intestinal wall, which in turn may worsen liver disease, according to research published in Cellular and Molecular Gastroenterology and Hepatology, the new basic science journal of the American Gastroenterological Association.
Sheila Sherlock Clinical and Translation Research Award, National Institutes of Health

Contact: Rachel Steigerwald
media@gastro.org
301-272-1603
American Gastroenterological Association

Public Release: 2-Apr-2015
Proceedings of the National Academy of Sciences
The brain-belly connection: Team finds genetic triggers in weight-regulating brain cells
The little voice inside your head that tells you to eat, or stop eating, isn't a little voice -- it's actually a cluster of about 10,000 specialized brain cells. And now, an international team of scientists has found tiny triggers inside those cells that give rise to this 'voice,' and keep it speaking throughout life.
NIH/National Institute of Diabetes and Digestive and Kidney Disorders

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 2-Apr-2015
New England Journal of Medicine
Some false postive prenatal genetic screens due to mother's extra DNA segments
In prenatal care, maternal blood screening for extra chromosomes in the fetus is becoming increasingly common. Such tests might give false-positive results if the mother's genome contains more than the usual number of certain DNA segments, especially if the fetus has inherited an elongated chromosome. The tests could be improved to account for the fact that chromosomes can vary in size and composition among people.
National Institutes of Health, Washington State Obstetrical Association, Howard Hughes Medical Institute

Contact: Leila Gray
leilag@uw.edu
206-685-0381
University of Washington Health Sciences/UW Medicine

Public Release: 2-Apr-2015
Cancer Letters
Nanoparticles may exploit tumor weaknesses to selectively attack cancers
Delving into the world of the extremely small, researchers are exploring how biodegradable nanoparticles can precisely deliver anticancer drugs to attack neuroblastoma, an often-deadly children's cancer. The approach may represent a new fourth arm of targeted pediatric cancer treatment, joining T-cell immunotherapy, radioactive isotopes and kinase inhibitors that disrupt cancer-driving signaling.
National Institutes of Health, Alex's Lemonade Stand Foundation, V Foundation

Contact: Rachel Salis-Silverman
Salis@email.chop.edu
267-426-6063
Children's Hospital of Philadelphia

Public Release: 2-Apr-2015
American Journal of Human Genetics
Study finds new genetic clues to pediatric seizure disorders
Researchers have identified a new genetic mutation at the heart of a severe and potentially deadly seizure disorder found in infants and young children. The finding, which was reported today in the journal American Journal of Human Genetics, may help scientists unravel the complex biological mechanism behind these diseases.
NIH/National Institutes of Neurological Disorders and Stroke

Contact: Mark Michaud
mark_michaud@urmc.rochester.edu
585-273-4790
University of Rochester Medical Center

Public Release: 2-Apr-2015
Cell Reports
Dual therapy's 1-2 punch knocks out drug-resistant lung cancer
Capitalizing on a rare opportunity to thoroughly analyze a tumor from a lung cancer patient who had developed resistance to targeted drug treatment, UC San Francisco scientists identified a biological escape hatch that explains the resistance, and developed a strategy in mice for shutting it down.
Bonnie J. Addario Lung Cancer Foundation, National Institutes of Health, Howard Hughes Medical Institute, Doris Duke Charitable Foundation, American Lung Association, Sidney Kimmel Foundation for Cancer Research, Searle Scholars Program, and others

Contact: Pete Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 2-Apr-2015
JAMA Ophthalmology
One test can predict which kids will become nearsighted
A study of 4,500 US children over 20 years has identified a single test that can predict which kids will become nearsighted by the eighth grade: a measure of their current refractive error.
NIH/National Eye Institute, Office of Minority Research/National Institutes of Health, Ohio Lions Eye Research Foundation, E.F. Wildermuth Foundation

Contact: Karla Zadnik
Zadnik.4@osu.edu
614-292-6603
Ohio State University

Showing releases 276-300 out of 3680.

<< < 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 > >>

     
   

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