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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 276-300 out of 3692.

<< < 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 > >>

Public Release: 29-Oct-2015
New class of DNA repair enzyme discovered
A new class of DNA repair enzyme has been discovered which demonstrates that a much broader range of damage can be removed from the double helix in ways that biologists did not think were possible.
National Science Foudation, National Institutes of Health

Contact: David F Salisbury
Vanderbilt University

Public Release: 29-Oct-2015
Developmental Cell
Hair-GEL online tool gives bird's eye view of hair follicle formation
Mount Sinai researchers create a resource to help uncover the molecular controls that generate skin and hair.
NIH/National Institute of Arthritis, Arthritis and Musculoskeletal and Skin Diseases, New York State Department of Health, Irma T. Hirschl Trust

Contact: Sid Dinsay
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 29-Oct-2015
Cell Metabolism
Gut bacteria could be blamed for obesity and diabetes
An excess of bacteria in the gut can change the way the liver processes fat and could lead to the development of metabolic syndrome, according to health researchers.
National Institutes of Health

Contact: Victoria M. Indivero
Penn State

Public Release: 29-Oct-2015
UTA, Ohio State partner to better understand and treat muscle loss
Scientists with The University of Texas at Arlington and Ohio State University have won a rare National Institute on Aging grant to research the molecular mechanisms of muscle aging that can lead to muscle loss and weakness.
NIH/National Institute on Aging

Contact: Bridget Lewis
University of Texas at Arlington

Public Release: 29-Oct-2015
Breast Cancer Research and Treatment
Exercise could give margin of safety to women who want to delay preventive mastectomy
Regular physical activity could play a role in helping women at high-risk of breast cancer delay the need for drastic preventive measures such as mastectomy. Results of the WISER Sister study help clarify the emerging connection between exercise and breast cancer risk. As a result of the new findings, the authors suggest women with an elevated breast cancer risk should consider doing 30 to 60 minutes of aerobic activity per day for five days per week.
National Institutes of Health

Contact: Katie Delach
University of Pennsylvania School of Medicine

Public Release: 29-Oct-2015
Cell Transplantation
Transplanted human umbilical cord blood cells may offer therapy for Alzheimer's sufferers
Researchers injected human umbilical cord blood cells into mice modeled with Alzheimer's disease to investigate how the cells were distributed and retained in tissues, including the brain. The study also investigated questions about the bioavailability and safety of the procedure. They found that the transplanted cells migrated to brain tissue, were retained there for up to 30 days, and did not promote the growth of tumors.
National Institutes of Health, Florida Hi Tech Corridor Matching Grant Program

Contact: Robert Miranda
Cell Transplantation Center of Excellence for Aging and Brain Repair

Public Release: 29-Oct-2015
Academy of Management Journal
Spinning out? What you're able to take with you to your new company will determine how well you do
To 'spin out,' you better have a big team with lots of experience. When it comes to leaving a company to start your own, whether you sink or swim could depend on how many good people you can bring with you.
National Science Foundation Grants, NIH/National Institute on Aging, Alfred P. Sloan Foundation, Social Science and Humanities Research Council of Canada

Contact: Ken McGuffin
University of Toronto, Rotman School of Management

Public Release: 29-Oct-2015
Breaking the mold: Untangling the jelly-like properties of diseased proteins
Scientists at the University of Cambridge have identified a new property of essential proteins which, when it malfunctions, can cause the build up, or 'aggregation', of misshaped proteins and lead to serious diseases.
Wellcome Trust, Medical Research Council, National Institutes of Health Research, Canadian Institutes of Health Research, National Institutes of Health

Contact: Craig Brierley
University of Cambridge

Public Release: 29-Oct-2015
TSRI study suggests tumors may 'seed' cancer metastases earlier than expected
A new study from scientists at The Scripps Research Institute helps explain why cancer metastasis is so hard to stop. The researchers found an additional mechanism explaining how a molecule long linked to cancer progression appears to 'seed' the body with metastatic cells long before doctors would typically detect a primary tumor.
National Institutes of Health, Swiss National Science Foundation

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 29-Oct-2015
$5.8 million NIH contract to Saint Louis University to fund 'omics' research
Saint Louis University's Vaccine Center is one of two sites in the nation selected by the NIH to conduct omics research on infectious diseases.
National Institutes of Health

Contact: Nancy Solomon
Saint Louis University

Public Release: 29-Oct-2015
Biofilms and Microbiomes
Study led by Temple researchers showcases potential new oral treatment for IBD
For patients with inflammatory bowel disease (IBD), the possibility of taking one pill to bring long-lasting relief might seem too good to be true. Scientists at the Lewis Katz School of Medicine at Temple University are on the brink of making that happen, thanks to a recent proof-of-concept study, in which the severity of a form of IBD in mice was dramatically reduced with one oral dose of a protein isolated from a bacterial biofilm.
National Institutes of Health, NIH/National Institute of Allergy and Infectious Diseases, Biostrategy Partners Pharma Germinator Program

Contact: Jeremy Walter
Temple University Health System

Public Release: 29-Oct-2015
PLOS Computational Biology
'Ensemble' modeling could lead to better flu forecasts, study finds
By combining data from a variety of non-traditional sources, a research team led by computational epidemiologists at Boston Children's Hospital has developed predictive models of flu-like activity that provide robust real-time estimates (aka 'now-casts') of flu activity and accurate forecasts of flu-like illness levels up to three weeks into the future.
NIH/National Library of Medicine, NIH/National Institute of Environmental Health Sciences

Contact: Keri Stedman
Boston Children's Hospital

Public Release: 29-Oct-2015
American Journal of Human Genetics
Cleveland Clinic researchers discover new thyroid cancer gene
Cleveland Clinic researchers have discovered a new gene associated with Cowden syndrome, an inherited condition that carries high risks of thyroid, breast, and other cancers, and a subset of non-inherited thyroid cancers, as published today in the online version of the American Journal of Human Genetics.
NIH/National Cancer Institute, American Cancer Society Clinical Research Professorship, Breast Cancer Research Foundation, William Randolph Hearst Foundations, Doris Duke Distinguished Clinical Scientist Award

Contact: Laura Ambro
Cleveland Clinic

Public Release: 29-Oct-2015
Lancet Diabetes & Endocrinology
Low-fat diet not most effective in long-term weight loss
The effectiveness of low-fat diet on weight-loss has been debated for decades, and hundreds of randomized clinical trials aimed at evaluating this issue have been conducted with mixed results. New research finds that low-fat interventions were no more successful than higher-fat interventions in achieving and maintaining weight loss for periods longer than one year.
National Institutes of Health, American Diabetes Association

Contact: Lori J. Schroth
Brigham and Women's Hospital

Public Release: 29-Oct-2015
Journal of Infectious Diseases
Studies raise questions about impact of statins on flu vaccination in seniors
A new pair of studies suggests that statins, drugs widely used to reduce cholesterol, may have a detrimental effect on the immune response to influenza vaccine and the vaccine's effectiveness at preventing serious illness in older adults. Published in The Journal of Infectious Diseases, the findings, if confirmed by additional research, may have implications for flu vaccine recommendations, guidelines for statin use around the time of vaccination, and future vaccine clinical trials in seniors.
Novartis Vaccines, Emory, NIH/National Institute of Allergy and Infectious Diseases

Contact: Stephanie Goldina
Infectious Diseases Society of America

Public Release: 29-Oct-2015
Cancer Cell
Immunotherapy for pancreatic cancer boosts survival by more than 75 percent in mice
A new study in mice by researchers at Fred Hutchinson Cancer Research Center has found that a specialized type of immunotherapy -- even when used without chemotherapy or radiation -- can boost survival from pancreatic cancer, a nearly almost-lethal disease, by more than 75 percent. The findings are so promising, human clinical trials are planned within the next year.
National Institutes of Health, Giles W. and Elise G. Mead Foundation, Juno Therapeutics

Contact: Kristen Woodward
Fred Hutchinson Cancer Research Center

Public Release: 29-Oct-2015
American Journal of Human Genetics
Stanford researchers identify potential security hole in genomic data sharing network
Hackers with access to a person's genome might find out if that genome is in an international network of disease databases.
National Institutes of Health

Contact: Jennie Dusheck
Stanford University Medical Center

Public Release: 29-Oct-2015
Cancer Discovery
Splicing alterations that cause resistance to CD19 CAR T-cell therapy identified
Resistance to CD19 CAR T-cell therapy, a type of immunotherapy that yields long-lasting remissions in many patients with B-cell leukemia, can be caused by CD19 splicing alterations, leading to loss of certain parts of the CD19 protein that are recognized by the CAR T cells.
V Foundation for Cancer Research, William Lawrence and Blanche Hughes Foundation, Leukemia and Lymphoma Society, Alex's Lemonade Stand, National Institutes of Health, SU2C-St. Baldrick's Foundation

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 29-Oct-2015
2015 American Association of Pharmaceutical Scientists Annual Meeting and Exposition
New enzyme therapy shows proof of concept as treatment for cocaine overdose
A long-acting enzyme that rapidly and safely metabolizes cocaine in the blood stream is currently being investigated in animal models as a possible treatment for cocaine overdose. This research is being presented Oct. 29 at the 2015 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting in Orlando, Fla. Oct. 25-29.
National Institutes of Health

Contact: Amanda Johnson
American Association of Pharmaceutical Scientists

Public Release: 29-Oct-2015
Cell Reports
Wistar scientists show how frequently mutated prostate cancer gene suppresses tumors
New research from The Wistar Institute has found how SPOP, a gene frequently mutated in prostate cancer, is able to halt tumors by inducing senescence, a state of stable cell cycle arrest, which means that the cells have stopped dividing and growing. With this new information, scientists may be able to design therapeutic strategies that can halt cancers caused by these mutated genes that are able to bypass senescence.
National Institutes of Health, US Department of Defense

Contact: Ben Leach
The Wistar Institute

Public Release: 28-Oct-2015
Proceedings of the National Academy of Sciences
Bacterial hole puncher could be new broad-spectrum antibiotic
Bacteria have many methods of adapting to resist antibiotics, but a new class of spiral polypeptides targets one thing no bacterium can live without: an outer membrane. The polypeptides act as bacterial hole-punchers, perforating the bacterial membrane until the cell falls apart. The antimicrobial agents are dressed for their mission in positively charged shells that let them travel in body fluids, protected from interacting with other proteins, and also attract them to bacterial membranes.
National Institutes of Health, National Science Foundation

Contact: Liz Ahlberg
University of Illinois at Urbana-Champaign

Public Release: 28-Oct-2015
To meet urgent need, UMass Amherst biologist will develop new liver model for research
At present, medical researchers lack experimental models and urgently need new ways to study liver function and mechanisms, especially because liver disease is on the rise due to the obesity crisis, and late-stage disease often requires an organ transplant. Now researcher Kim Tremblay at the University of Massachusetts Amherst has received a grant to develop a promising new model liver system.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Janet Lathrop
University of Massachusetts at Amherst

Public Release: 28-Oct-2015
Journal of Alzheimer's Disease
UCI study finds jet lag-like sleep disruptions spur Alzheimer's memory, learning loss
Chemical changes in brain cells caused by disturbances in the body's day-night cycle may be a key underlying cause of the learning and memory loss associated with Alzheimer's disease, according to a University of California, Irvine study. The research on mice provides the first evidence that circadian rhythm-altering sleep disruptions similar to jet lag promote memory problems and chemical alterations in the brain.
National Institutes of Health

Contact: Tom Vasich
University of California - Irvine

Public Release: 28-Oct-2015
Psychological Science
Older beats younger when it comes to correcting mistakes
Findings from a new study challenge the notion that older adults always lag behind their younger counterparts when it comes to learning new things. The study, published in Psychological Science, a journal of the Association for Psychological Science, shows that older adults were actually better than young adults at correcting their mistakes on a general information quiz.
NIH/National Institute on Aging, James S. McDonnell Foundation

Contact: Anna Mikulak
Association for Psychological Science

Public Release: 28-Oct-2015
Journal of Law, Medicine & Ethics
Guidelines on sharing individual genomic research findings with family
A blue-ribbon project group funded by the National Institutes of Health has published the first consensus guidelines on how researchers should share genomic findings in research on adults and children with other family members. The recommendations, published in the Journal of Law, Medicine & Ethics, offer direction on sharing information before and after the death of an individual research participant.
National Institutes of Health

Contact: Joe Dangor
Mayo Clinic

Showing releases 276-300 out of 3692.

<< < 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 > >>


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