Key: Meeting      Journal      Funder

Showing releases 2776-2800 out of 3339.

<< < 107 | 108 | 109 | 110 | 111 | 112 | 113 | 114 | 115 | 116 > >>

Public Release: 22-Jul-2012
Nature
Key mutations discovered for most common childhood brain cancer
Researchers at Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) linked mutations in specific genes to four subtypes of medulloblastoma, the most common malignant brain tumor of children. The discovery, reported July in journal Nature, provides potential biomarkers for guiding and individualizing treatment and reveals prospective therapeutic opportunities for countering this devastating malignancy. For the first time, it's possible to classify and treat medulloblastoma based on molecular typing, providing the best therapy with the fewest long-term consequences.
NIH/National Human Genome Research Institute, NIH/National Cancer Institute, NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of Child Health and Human Development, others

Contact: Meghan Weber
meghan.weber@childrens.harvard.edu
617-919-3110
Boston Children's Hospital

Public Release: 22-Jul-2012
Nature Biotechnology
Artificial jellyfish swims in a heartbeat
A team of researchers at Harvard University and the California Institute of Technology have turned inanimate silicone and living cardiac muscle cells into a freely swimming "jellyfish." The finding serves as a proof of concept for reverse engineering a variety of muscular organs and simple life forms.
Wyss Institute for Biologically Inspired Engineering at Harvard, National Science Foundation, National Institutes of Health, Office of Naval Research

Contact: Michael Patrick Rutter
mrutter@seas.harvard.edu
617-496-3815
Harvard University

Public Release: 22-Jul-2012
XIX International AIDS Conference
For gay couples, condom decision-making and condom use varies by race
Black gay couples tend to practice safe sex but don't talk about it, while white gay couples discuss safety but are less likely to use condoms, according to new findings presented at the 19th International AIDS Conference. San Francisco State University researchers studied male couples in San Francisco and New York and explored the differences in how black, white and interracial male couples make decisions about using condoms with their primary partner.
National Institutes of Health

Contact: Elaine Bible
ebible@sfsu.edu
415-405-3606
San Francisco State University

Public Release: 20-Jul-2012
Marshall University scientist awarded NIH grant for lung cancer research
A Marshall University faculty member has been awarded a three-year, $426,000 grant by the National Institutes of Health (NIH) to further her research to determine if the nutritional agent capsaicin -- the active ingredient in chili peppers -- can improve the anti-cancer activity of the commonly used chemotherapy drug cisplatin in patients with small cell lung cancer.
National Institutes of Health

Contact: Ginny Painter
ginny.painter@marshall.edu
304-746-1964
Marshall University Research Corporation

Public Release: 19-Jul-2012
Expert Opinion on Drug Discovery
3-D tumor models improve drug discovery success rate
Imagine millions of cancer cells organized in thousands of small divots. Hit these cells with drugs and when some cells die, you have a candidate for a cancer drug. But a review published this week in the journal Expert Opinion on Drug Discovery argues that these 2-D models in fact offer very little information about a potential drug's effects in the body and may often give researchers misleading results.
NIH/National Eye Institute

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 19-Jul-2012
Journal of the National Cancer Institute
Meta-analysis: Interventions improve depression in cancer patients
Despite guidelines recommending screening for depression in cancer patients, it's been unclear whether interventions designed to treat this depression are effective. A study by the University of Colorado Cancer Center and other institutions, published in the Journal of the National Cancer Institute, changes that. This meta-analysis of 10 studies encompassing 1362 patients shows that especially cognitive behavioral therapy and pharmacologic interventions decrease depressive symptoms in cancer patients.
NIH/National Cancer Institute

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 19-Jul-2012
Journal of Medicinal Chemistry
Novel anti-malarial drug target identified
An international team of scientists, led by researchers from the Department of Pediatrics at the University of California, San Diego School of Medicine, have identified the first reported inhibitors of a key enzyme involved in survival of the parasite responsible for malaria. Their findings, which may provide the basis for anti-malarial drug development, are currently published in the online version of the Journal of Medicinal Chemistry.
National Institutes of Health, Deutsche Forschungsgemeinschaft

Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 19-Jul-2012
Journal of American Geriatrics Society
Elder abuse affects Latinos disproportionately
"Our study has revealed a much higher rate of elder abuse among the Latino community than had been previously thought," said Marguerite DeLiema of the USC Davis School of Gerontology, lead author of the study in the Journal of the American Geriatrics Society. "This indicates that family solidarity within the Latino community does not necessarily protect older Latinos against elder abuse, as some research has suggested."
NIH/National Institute on Aging

Contact: Suzanne Wu
suzanne.wu@usc.edu
213-740-0252
University of Southern California

Public Release: 19-Jul-2012
University of Texas Medical Branch to study hospital readmission
A research team at the University of Texas Medical Branch has received a grant of nearly $1 million from the National Institutes of Health to study why some patients are more likely to be readmitted to a hospital shortly after they are discharged.
National Institutes of Health

Contact: Molly Dannenmaier
mjdannen@utmb.edu
409-772-8790
University of Texas Medical Branch at Galveston

Public Release: 19-Jul-2012
Cell Host & Microbe
Scripps Research scientists show potent new compound virtually eliminates HIV in cell culture
A new study by scientists on the Florida campus of The Scripps Research Institute shows, in cell culture, a natural compound can virtually eliminate human immunodeficiency virus (HIV) in infected cells.
NIH/National Institute of Allergy and Infectious Diseases, Landenberger Foundation

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 19-Jul-2012
Journal of the American Geriatrics Society
A good night's sleep could keep you out of a nursing home
Fragmented or interrupted sleep could predict future placement in a nursing home or assisted living facility.
NIH/National Institute on Aging, National Institutes of Health

Contact: Natalie Wood-Wright
nwoodwri@jhsph.edu
410-614-6029
Johns Hopkins University Bloomberg School of Public Health

Public Release: 19-Jul-2012
8th International Conference on Head & Neck Cancer
HPV improves survival for African-Americans with throat cancer
According to a new Henry Ford Hospital study, HPV has a substantial impact on overall survival in African-Americans with oropharyngeal cancer, a cancer that affects part of the throat, the base of the tongue, the tonsils, the soft palate (back of the mouth), and the walls of the pharynx (throat). The study shows African Americans who are HPV positive have better outcomes than African-Americans without HPV.
National Institutes of Health

Contact: Krista Hopson
khopson1@hfhs.org
313-874-7207
Henry Ford Health System

Public Release: 19-Jul-2012
JAMA
Herbal remedy used to treat hepatitis C proves ineffective, Penn study finds
Silymarin, an extract of milk thistle commonly used to treat chronic liver disease by millions of people around the World, does not offer significant improvements for patients, according to a new study conducted by a nationwide group of researchers including faculty at the Perelman School of Medicine at the University of Pennsylvania.
NIH/National Center for Complementary and Alternative Medicine

Contact: Katie Delach
katie.delach@uphs.upenn.edu
215-349-5964
University of Pennsylvania School of Medicine

Public Release: 19-Jul-2012
New study announced that will use genetics to test for Alzheimer's risk
In a new Alzheimer's disease risk assessment study, researchers at Brigham and Women's Hospital are offering genetic testing and Alzheimer's risk estimates for people who are experiencing mild cognitive impairment. The study's goal is to determine how people with mild cognitive impairment and their caregivers respond to health education and genetic testing.
National Institutes of Health

Contact: Tom Langford
tlangford@partners.org
617-534-1605
Brigham and Women's Hospital

Public Release: 19-Jul-2012
Cell
Hundreds of random mutations in leukemia linked to aging, not cancer
Hundreds of mutations exist in leukemia cells at the time of diagnosis, but nearly all occur randomly as a part of normal aging and are not related to cancer, new research shows.
NIH/National Human Genome Research Institute, NIH/National Cancer Institute, Barnes-Jewish Hospital Foundation

Contact: Caroline Arbanas
arbanasc@wustl.edu
314-286-0109
Washington University School of Medicine

Public Release: 19-Jul-2012
Molecular Cell
Inflammatory pathway spurs cancer stem cells to resist HER2-targeted breast cancer treatment
Researchers at the University of Michigan Comprehensive Cancer Center have discovered one reason why cancer cells become resistant to herceptin: they turn on a completely different pathway, one that is involved in inflammation, fueling the cancer independently of HER2.
National Institutes of Health, Susan G. Komen for the Cure

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 19-Jul-2012
Structure
Viruses' copying mechanism demystified, opening the door to new vaccine strategies
Certain kinds of viruses such as those that cause the common cold and hepatitis, copy themselves using a unique mechanism, according to a team of Penn State University scientists. The discovery sheds light on a never-before-understood region of an enzyme associated with the process of replicating genetic material. The research is an important step toward designing vaccines against viruses that have eluded vaccination strategies in the past, and improving existing vaccines.
National Institutes of Health

Contact: Barbara K. Kennedy
science@psu.edu
814-863-4682
Penn State

Public Release: 19-Jul-2012
Molecular Cell
Does presence of oxidants early in life help determine life span?
Why do we age, and what makes some of us live longer than others? For decades, researchers have been trying to answer these questions by elucidating the molecular causes of aging.
NIH/National Institute of Aging, NIH/National Center for Research Resources, National Institutes of Health

Contact: Jim Erickson
ericksn@umich.edu
734-647-1842
University of Michigan

Public Release: 19-Jul-2012
Cell
Stanford researchers first to determine entire genetic sequence of individual human sperm
The entire genomes of 91 human sperm from one man have been sequenced by Stanford University researchers. The results provide a fascinating glimpse into naturally occurring genetic variation in one individual, and are the first to report the whole-genome sequence of a human gamete -- the only cells that become a child and through which parents pass on physical traits.
National Institutes of Health, Chinese Scholarship Council, Siebel Foundation

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center

Public Release: 19-Jul-2012
Cell
The Yin and Yang of stem cell quiescence and proliferation
Not all adult stem cells are created equal. Some are busy regenerating worn out or damaged tissues, while their quieter brethren serve as a strategic back-up crew that only steps in when demand shoots up. Now, researchers at the Stowers Institute for Medical Research have identified an important molecular cue that keeps quiescent mouse hematopoietic (or blood-forming) stem cells from proliferating when their services are not needed.
Stowers Institute for Medical Research, National Institutes of Health

Contact: Gina Kirchweger
gxk@stowers.org
816-806-1036
Stowers Institute for Medical Research

Public Release: 19-Jul-2012
Cell
Debate ends: Everyone was right
Scientists at the Stowers Institute of Medical Research have developed an innovative method to count the number of fluorescent molecules in a cluster and then applied the novel approach to settle a debate rampant among cell biologists -- namely, how DNA twists into a unique chromosomal structure called the centromere. Knowing this helps explain how cells navigate the hazards of division and avoid the disastrous consequences of ending up with the wrong number of chromosomes.
NIH/National Institute of General Medical Sciences

Contact: Gina Kirchweger
gxk@stowers.org
816-806-1036
Stowers Institute for Medical Research

Public Release: 19-Jul-2012
Cell
New technique reveals cross-talk between 2 essential cellular processes
Scientists at the Scripps Research Institute have simultaneously mapped two of the most important types of protein-modification in cells, revealing their extensive cooperation during an essential cellular process.
National Institutes of Health, California Breast Cancer Foundation, ActivX Biosciences, ARCS Foundation, Skaggs Institute for Chemical Biology at Scripps Research

Contact: Mika Ono
mikaono@scripps.edu
Scripps Research Institute

Public Release: 19-Jul-2012
Cell
Like a transformer? Protein unfolds and refolds for new function
New research has shown that a protein does something that scientists once thought impossible: It unfolds itself and refolds into a completely new shape. When the protein refolds, it acquires a new function – yet another finding that researchers would not have predicted.
National Institutes of Health, German Research Foundation

Contact: Irina Artsimovitch
Artsimovitch.1@osu.edu
614-292-6777
Ohio State University

Public Release: 18-Jul-2012
This is your brain on pain
University of Texas Medical Branch at Galveston professor Volker Neugebauer has been awarded a four-year, $1.36 million grant by the National Institute of Neurological Disorders and Stroke to conduct an innovative study of the relationship between pain and parts of the brain associated with cognitive thought and emotional response.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston

Public Release: 18-Jul-2012
FASEB Journal
Lungs respond to hospital ventilator as if it were an infection
When hospital patients need assistance breathing and are placed on a mechanical ventilator for days at a time, their lungs react to the pressure generated by the ventilator with an out-of-control immune response that can lead to excessive inflammation, new research suggests.
National Institutes of Health, American Heart Association, National Science Foundation

Contact: Samir Ghadiali, (614) 247-1849; Ghadiali.1@osu.edu
Ghadiali.1@osu.edu
614-247-1849
Ohio State University

Showing releases 2776-2800 out of 3339.

<< < 107 | 108 | 109 | 110 | 111 | 112 | 113 | 114 | 115 | 116 > >>