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Department of Health and Human Services

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Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 2876-2900 out of 3607.

<< < 111 | 112 | 113 | 114 | 115 | 116 | 117 | 118 | 119 | 120 > >>

Public Release: 18-May-2014
Nature Methods
Illuminating neuron activity in 3-D
Researchers at MIT and the University of Vienna have created an imaging system that reveals neural activity throughout the brains of living animals.
Allen Institute for Brain Science, National Institutes of Health, MIT Synthetic Intelligence Project, IET Harvey Prize, National Science Foundation, New York Stem Cell Foundation, Google, and others

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Public Release: 18-May-2014
ATS 2014
JAMA
Study finds limited benefit for vitamin D in asthma treatment
Adding vitamin D to asthma treatment to improve breathing only appears to benefit patients who achieve sufficient levels of the supplement in the blood. Overall, the ability to control asthma did not differ between a study group that received vitamin D supplements and a group that received placebo, according to new research at Washington University School of Medicine in St. Louis.
National Institutes of Health

Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine

Public Release: 18-May-2014
ATS 2014
New England Journal of Medicine
Statins fail to reduce mortality rate in sepsis patients with ARDS
Despite previously-reported observational and basic science evidence suggesting the use of statins may improve outcomes in patients with sepsis and acute respiratory distress syndrome, a double-blinded clinical trial of rosuvastatin in those patients was futile, and the study was halted.
Astrazeneca, NIH/National Heart, Lung, and Blood Institute

Contact: Maureen Mack
mmack@mcw.edu
414-955-4744
Medical College of Wisconsin

Public Release: 18-May-2014
ATS 2014
New England Journal of Medicine
Temple-led study finds no benefit in taking statin drugs for COPD exacerbation prevention
A statin drug commonly used to lower cholesterol is not effective in reducing the number and severity of flare ups from chronic obstructive pulmonary disease (COPD), according to the results of a large multicenter clinical trial designed and directed by Gerard J. Criner, M.D., of Temple University Hospital in Philadelphia, Pa. The study rigorously tested the hypothesis that statin drugs may be beneficial to persons with COPD because of the drugs' purported anti-inflammatory effect.
NIH/National Heart, Lung, and Blood Institute, Canadian Institutes of Health Research

Contact: Jeremy Walter
Jeremy.Walter@tuhs.temple.edu
215-707-7882
Temple University Health System

Public Release: 18-May-2014
Nature Medicine
Cedars-Sinai study identifies heart-specific protein that protects against arrhythmia
Researchers at the Cedars-Sinai Heart Institute have identified a heart-specific form of a protein, BIN1, responsible for sculpting tiny folds in pockets that are present on the surface of heart muscle cells. The study provides the first direct evidence of a previously theoretical 'fuzzy space' or 'slow diffusion zone' that protects against irregular heartbeats by maintaining an ideal concentration of electrochemical molecules.
National Institutes of Health, American Heart Association

Contact: Sally Stewart
sally.stewart@cshs.org
310-248-6566
Cedars-Sinai Medical Center

Public Release: 16-May-2014
Journal of the National Cancer Institute
Herpes-loaded stem cells used to kill brain tumors
Harvard Stem Cell Institute scientists at Massachusetts General Hospital have a potential solution for how to more effectively kill tumor cells using cancer-killing viruses. The investigators report that trapping virus-loaded stem cells in a gel and applying them to tumors significantly improved survival in mice with glioblastoma multiform, the most common brain tumor in human adults and also the most difficult to treat.
James S. McDonnell Foundation, National Institutes of Health

Contact: Joseph Caputo
joseph_caputo@harvard.edu
617-496-1491
Harvard University

Public Release: 16-May-2014
Annals of Rheumatic Diseases
Molecules involved in rheumatoid arthritis angiogenesis identified
Two protein molecules that fit together as lock and key seem to promote the abnormal formation of blood vessels in joints affected by rheumatoid arthritis, according to researchers at the University of Illinois at Chicago College of Medicine, who found that the substances are present at higher levels in the joints of patients affected by the disease.
National Institutes of Health, US Department of Defense, American College of Rheumatology, Arthritis Foundation

Contact: Sharon Parmet
sparmet@uic.edu
312-413-2695
University of Illinois at Chicago

Public Release: 16-May-2014
American Urological Association Annual Meeting
JAMA Surgery
Non-invasive lithotripsy leads to more treatment for kidney stones
When it comes to treating kidney stones, less invasive may not always be better, according to new research from Duke Medicine. In a direct comparison of shock wave lithotripsy vs. ureteroscopy -- the two predominant methods of removing kidney stones -- researchers found that ureteroscopy resulted in fewer repeat treatments.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

Public Release: 16-May-2014
Journal of Clinical Investigation
Gender differences stand out in measuring impact of Viagra as therapy for heart failure
New animal studies by Johns Hopkins cardiovascular researchers strongly suggest that sildenafil, the erectile dysfunction drug sold as Viagra and now under consideration as a treatment for heart failure, affects males and females very differently
NIH/National Heart, Blood and Lung Institute, American Heart Association

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine

Public Release: 16-May-2014
Journal of Clinical Investigation
Breakthrough in HIV/AIDS research gives hope for improved drug therapy
The first direct proof of a long-suspected cause of multiple HIV-related health complications was recently obtained by a team led by the University of Pittsburgh Center for Vaccine Research. The finding supports complementary therapies to antiretroviral drugs to significantly slow HIV progression.
National Institutes of Health

Contact: Allison Hydzik
hydzikam@upmc.edu
412-647-9975
University of Pittsburgh Schools of the Health Sciences

Public Release: 16-May-2014
PLOS ONE
MicroRNA that could be used to suppress prostate cancer progression found
About one in seven men will develop prostate cancer over the course of a lifetime, and about one in 36 men will die from it. This is why findings by Cincinnati Cancer Center researchers, showing that a tumor suppressive microRNA, when activated by an anti-estrogen drug, could contribute to development of future targeted therapies, are important.
Hong Kong University, Chinese University of Hong Kong, NIH/National Cancer Institute, VA, AstraZeneca

Contact: Katie Pence
katie.pence@uc.edu
513-558-4561
University of Cincinnati Academic Health Center

Public Release: 16-May-2014
Human Reproduction
Male infertility linked to mortality in study led by Stanford researcher
Men who are infertile because of defects in their semen appear to be at increased risk of dying sooner than men with normal semen, according to a study led by a researcher at the Stanford University School of Medicine. Men with two or more abnormalities in their semen were more than twice as likely to die over a roughly eight-year period as men who had normal semen, the study found.
National Institutes of Health

Contact: Bruce Goldman
goldmanb@stanford.edu
650-725-2106
Stanford University Medical Center

Public Release: 16-May-2014
Cancer Epidemiology, Biomarkers & Prevention
Water pipe smoking causes significant exposure to nicotine and cancer-causing agents
Young adults who smoked water pipes in hookah bars had elevated levels of nicotine, cotinine, tobacco-related cancer-causing agents, and volatile organic compounds in their urine, and this may increase their risk for cancer and other chronic diseases, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
National Institutes of Health, California Tobacco-related Disease Research Program

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 15-May-2014
Diabetes
Mothers' sleep, late in pregnancy, affects offspring's weight gain as adults
Poor-quality sleep during the third trimester of pregnancy can increase the odds of weight gain and metabolic abnormalities in offspring once they reach adulthood. The effects, caused by epigenetic modifications, impose lasting consequences on the next generation.
National Institutes of Health

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Public Release: 15-May-2014
JAMA Internal Medicine
'Physician partners' free doctors to focus on patients, not paperwork
Primary care doctors now spend so much time on clerical duties such as entering data into patient records that their time with patients is severely curtailed. A new UCLA study suggests that 'physician partners,' whose role would be to work on those time consuming administrative tasks, can free up physicians' time so that they can focus more of their attention on their patients, leading to greater patient satisfaction with their care.
University of California - Los Angeles Claude Pepper Older Americans Independence Center, NIH/National Institute on Aging

Contact: Enrique Rivero
erivero10@netscape.net
310-597-5768
University of California - Los Angeles Health Sciences

Public Release: 15-May-2014
Drug and Alcohol Dependence
Marijuana use involved in more fatal accidents in Colorado
The proportion of marijuana-positive drivers involved in fatal motor vehicle crashes in Colorado has increased dramatically since the commercialization of medical marijuana in the middle of 2009, according to a study by University of Colorado School of Medicine researchers.
NIH/National Institute on Drug Abuse, NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Mark Couch
mark.couch@ucdenver.edu
303-724-5377
University of Colorado Denver

Public Release: 15-May-2014
Journal of Experimental Medicine
Penn Vet study reveals Salmonella's hideout strategy
A study led by researchers in the University of Pennsylvania's School of Veterinary Medicine reveals how some Salmonella bacteria hide from the immune system, allowing them to persist and cause systemic infection.
National Institutes of Health, University Research Foundation, McCabe Fund

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 15-May-2014
National Institutes of Health funding to help expand data storage capacity at UC Riverside
The University of California, Riverside, has received funding of $600,000 from the National Institutes of Health to support data-intensive research -- also often called Big Data science. The grant will make possible the purchase of a complex instrument: a Big Data cluster with high-performance CPU resources and data storage space equivalent to 5,000 modern laptops. Big Data has been identified as a contributor to the growth of the US economy over the next few decades.
National Institutes of Health

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Public Release: 15-May-2014
Substance Abuse
Anti-craving drug and counseling lower alcohol harm in homeless, without sobriety demands
Abstinence-based treatment has not been effective for many homeless people with alcohol dependence. They might benefit from an intervention that does not require them to stop or reduce drinking, according a preliminary Seattle study. Participants received monthly injections of an anti-craving medication, extended-release naltrexone. They met regularly with physicians to set their own treatment goals and to learn to be safer in their alcohol use. Early findings suggest this approach may reduce alcohol-related problems.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Leila Gray
leilag@uw.edu
206-685-0381
University of Washington

Public Release: 15-May-2014
Nature Structural & Molecular Biology
Detailed studies reveal how key cancer-fighting protein is held in check
St. Jude Children's Research Hospital scientists have mapped the structural details of how p53 attaches to its regulatory protein, called BCL-xL, in the cell. The protein p53 is a key activator of the cell's protective machinery against genetic damage, such as the mutations that drive cancer cells' explosive growth.
National Institutes of Health, NIH/National Cancer Institute, American-Lebanese-Syrian Associated Charities

Contact: Summer Freeman
summer.freeman@stjude.org
901-595-3061
St. Jude Children's Research Hospital

Public Release: 15-May-2014
Psychological Science
Mothers' symptoms of depression predict how they respond to child behavior
Depressive symptoms seem to focus mothers' responses on minimizing their own distress, which may come at the expense of focusing on the impact their responses have on their children, according to research published in Psychological Science, a journal of the Association for Psychological Science.
NIH/National Institute of Child Health and Human Development

Contact: Anna Mikulak
amikulak@psychologicalscience.org
202-293-9300
Association for Psychological Science

Public Release: 15-May-2014
Proceedings of the Royal Society B
The color of blood: Pigment helps stage symbiosis in squid
The relationship between the Hawaiian bobtail squid and the bacterium Vibrio fischeri is well chronicled, but writing in the current issue of the journal Proceedings of the Royal Society B, a group led by University of Wisconsin-Madison microbiologists Margaret McFall-Ngai, Edward Ruby and their colleagues adds a new wrinkle to the story.
Marie Curie Actions, National Science Foundation, National Institutes of Health

Contact: Margaret McFall-Ngai
mjmcfallngai@wisc.edu
608-262-2393
University of Wisconsin-Madison

Public Release: 15-May-2014
Biological Psychiatry
Effects of alcohol in young binge drinkers predicts future alcoholism
Heavy social drinkers who report greater stimulation and reward from alcohol are more likely to develop alcohol use disorder over time, report researchers from the University of Chicago, May 15 in the journal Biological Psychiatry. The findings run counter to existing hypotheses that innate tolerance to alcohol drives alcoholism.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Kevin Jiang
kevin.jiang@uchospitals.edu
773-795-5227
University of Chicago Medical Center

Public Release: 15-May-2014
Immunity
'Bystander' chronic infections thwart development of immune cell memory
Studies of vaccine programs in the developing world have revealed that individuals with chronic infections such as malaria and hepatitis tend to be less likely to develop the fullest possible immunity benefits from vaccines for unrelated illnesses. Researchers have found that chronic bystander viral or parasitic infections impaired the development of memory T cells in mouse models of long-term infection and in immune cells of people chronic hepatitis C infection.
NIH/National Institutes of Allergy and Infectious Diseases

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 15-May-2014
Stem Cell Reports
Combination therapy a potential strategy for treating Niemann Pick disease
Whitehead Institute researchers have identified a potential dual-pronged approach to treating Niemann-Pick type C (NPC) disease, a rare but devastating genetic disorder. By studying nerve and liver cells grown from NPC patient-derived induced pluripotent stem cells (iPSCs), the scientists determined that although cholesterol does accumulate abnormally in the cells of NPC patients, a more significant problem may be defective autophagy -- a basic cellular function that degrades and recycles unneeded or faulty molecules, components, or organelles in a cell.
National Niemann-Pick Disease Foundation, University of Cambridge, National Institutes of Health, Skoltech Center

Contact: Nicole Giese Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

Showing releases 2876-2900 out of 3607.

<< < 111 | 112 | 113 | 114 | 115 | 116 | 117 | 118 | 119 | 120 > >>

     
   

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