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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 2901-2925 out of 3572.

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Public Release: 9-Apr-2014
Nature Cell Biology
UNC researchers show how cancer cells may respond to mechanical force
Two UNC-Chapel Hill studies, published in Nature Cell Biology and the Journal of Immunology, identify the processes and cellular pathways that allow cells to move, stiffen, and react to physical stresses. This knowledge, researchers hope, could reveal the causes of cancer and help develop treatments, including therapies for a variety of diseases.
National Institutes of Health

Contact: William Davis
University of North Carolina Health Care

Public Release: 9-Apr-2014
UC San Diego researchers develop bacterial 'FM radio'
A team of biologists and engineers at UC San Diego has developed a 'rapid and tunable post-translational coupling' for genetic circuits.
National Institutes of Health, National Science Foundation

Contact: Kim McDonald
University of California - San Diego

Public Release: 9-Apr-2014
A bad penny: Cancer's thirst for copper can be targeted
Drugs used to block copper absorption for a rare genetic condition may find an additional use as a treatment for certain types of cancer, researchers at Duke Medicine report.
National Institutes of Health

Contact: Sarah Avery
Duke University Medical Center

Public Release: 9-Apr-2014
Novel approach to accelerate metabolism could lead to new obesity treatment
By manipulating a biochemical process that underlies cells' energy-burning abilities, investigators at Beth Israel Deaconess Medical Center have made a novel discovery that could lead to a new therapy to combat obesity and diabetes.
National Institutes of Health, JPB Foundation, Klarman Foundation, Deutsche Forschungsgemeinschaft, American Heart Association, Ellison Medical Foundation, Academy of Finland Grant.

Contact: Bonnie Prescott
Beth Israel Deaconess Medical Center

Public Release: 9-Apr-2014
New England Journal of Medicine
Spironolactone not reduce primary outcome, did reduce hospitalizations for heart failure
Findings from the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist trial, have revealed that adding the medication known as spironolactone to existing therapy did not significantly reduce the composite time to either death from cardiovascular causes, surviving a cardiac arrest, or hospitalization to manage heart failure in patients with heart failure and a preserved ejection fraction.
NIH/National Heart, Lung and Blood Institute, National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
Brigham and Women's Hospital

Public Release: 8-Apr-2014
Journal of Clinical Investigation
BU researchers identify specific causes of brown fat cell 'whitening'
Boston University researchers have learned new information about the consequences of overeating high-calorie foods. Not only does this lead to an increase in white fat cell production, the type prominent in obesity, but it also leads to the dysfunction of brown fat cells, the unique type of fat that generates heat and burns energy.
National Institutes of Health

Contact: Jenny Eriksen Leary
Boston University Medical Center

Public Release: 8-Apr-2014
Alcoholism: Clinical & Experimental Research
National survey links teen binge drinking and alcohol brand references in pop music
A study links brand mentions in popular music lyrics to binge drinking in teens and young adults. The influence of music was found to be as strong as peer and parental influence on drinking patterns.
National Institutes of Health, NIH/National Cancer Institute

Contact: Donna Dubuc
The Geisel School of Medicine at Dartmouth

Public Release: 8-Apr-2014
American Association for Cancer Research (AACR) Annual Meeting 2014
Deep, integrated genomic analysis re-classifies lower-grade brain tumors
Comprehensive genomic analysis of low-grade brain tumors sorts them into three categories, one of which has the molecular hallmarks and shortened survival of glioblastoma multiforme.
NIH/National Cancer Institute

Contact: Scott Merville
University of Texas M. D. Anderson Cancer Center

Public Release: 8-Apr-2014
Rapid, broad countermeasures sought against mystery infections
A group of University of Washington scientists is seeking broad, versatile countermeasures effective against several different kinds of viruses and other pathogens. The investigators are part of a national push for faster responses to unexpected infectious agents. These include newly emerging, unknown pathogens, forgotten ones, those expanding beyond their usual geographic range, or dangerous new strains of old enemies like influenza.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Leila Gray
University of Washington

Public Release: 8-Apr-2014
Experimental drug shows promise for treatment-resistant leukemias
Research in mice and human cell lines has identified an experimental compound dubbed TTT-3002 as potentially one of the most potent drugs available to block genetic mutations in cancer cells blamed for some forms of treatment-resistant leukemia.
NIH/National Cancer Institute

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 8-Apr-2014
Alcoholism: Clinical & Experimental Research
Why binge drinkers are slower to heal from their wounds
People who are injured while binge drinking are much slower to heal from wounds suffered in car accidents, shootings, fires, etc. Now a new study is providing insights into why alcohol has such a negative effect on wound healing: Binge alcohol exposure significantly reduced levels of key components of the immune system involved in healing.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Jim Ritter
Loyola University Health System

Public Release: 8-Apr-2014
Kinesin-5 structure opens cancer drug targets
The structure of a key part of the machinery that allows cells to divide has been identified by researchers at UC Davis -- opening new possibilities for throwing a wrench in the machine and blocking runaway cell division in cancer.
National Institutes of Health

Contact: Andy Fell
University of California - Davis

Public Release: 8-Apr-2014
DNA modifications measured in blood signal related changes in the brain
Johns Hopkins researchers say they have confirmed suspicions that DNA modifications found in the blood of mice exposed to high levels of stress hormone -- and showing signs of anxiety -- are directly related to changes found in their brain tissues.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 8-Apr-2014
Biological Psychiatry
Intranasal ketamine confers rapid antidepressant effect in depression
A research team from the Icahn School of Medicine at Mount Sinai published the first controlled evidence showing that an intranasal ketamine spray conferred an unusually rapid antidepressant effect -- within 24 hours -- and was well tolerated in patients with treatment-resistant major depressive disorder.
National Institutes of Health

Contact: Press Office
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 8-Apr-2014
Nature Communications
Blocking DNA repair mechanisms could improve radiation therapy for deadly brain cancer
UT Southwestern Medical Center researchers have demonstrated in both cancer cell lines and in mice that blocking critical DNA repair mechanisms could improve the effectiveness of radiation therapy for highly fatal brain tumors called glioblastomas.
National Institutes of Health, NASA, Cancer Prevention and Research Institute of Texas

Contact: Russell Rian
UT Southwestern Medical Center

Public Release: 8-Apr-2014
New epidemiology model combines multiple genomic data
Data about DNA differences, gene expression, or methylation can each tell epidemiologists something about the link between genomics and disease. A new statistical model that can integrate all those sources provides a markedly improved analysis, according to two new papers.
National Institutes of Health, Brown University

Contact: David Orenstein
Brown University

Public Release: 8-Apr-2014
Breast cancer cell subpopulation cooperation can spur tumor growth
Sub-populations of breast cancer cells sometimes cooperate to aid tumor growth, according to Penn State College of Medicine researchers, who believe that understanding the relationship between cancer sub-populations could lead to new targets for cancer treatment.
NIH/National Cancer Institute, Mary Kay Foundation

Contact: Matthew Solovey
Penn State

Public Release: 8-Apr-2014
Children's National researchers receive NIH grant for pediatric acute myelogenous leukemia treatment
A $1.92 million grant from the National Institutes of Health was awarded to a research team that focuses on new approaches for treatment of relapsed pediatric acute myelogenous leukemia, led by Yang Liu, Ph.D., Bothworth Chair and Director of the Center for Cancer and Immunology Research (CCIR) at Children's Research Institute of Children's National Health System, and Reuven Schore, M.D., member of CCIR.
National Institutes of Health

Contact: Joe Cantlupe
Children's National Medical Center

Public Release: 8-Apr-2014
Health Affairs
Back to basics: Redesigning systems of care for older adults with Alzheimer's disease
In a paper published in the April issue of the peer-reviewed journal Health Affairs, Regenstrief Institute investigator Christopher M. Callahan, M.D., founding director of the Indiana University Center for Aging Research, reviews two new dementia care models that seek to decrease stress for caregivers, reduce health care costs and improve quality of care for older adults.
NIH/National Institute on Aging

Contact: Cindy Fox Aisen
Indiana University

Public Release: 8-Apr-2014
Journal of General Internal Medicine
Good provider communication improves antidepressant adherence for diabetes patients
Adult patients with diabetes who trust their medical provider and feel included in treatment decisions are significantly more likely to take and maintain a newly prescribed antidepressant medication, according to a new study in the Journal of General Internal Medicine.
National Institutes of Health

Contact: Vincent Staupe
Kaiser Permanente

Public Release: 8-Apr-2014
Journal of Neuroscience
Processing new information during sleep compromises memory
New research appearing in the April 9 issue of the Journal of Neuroscience highlights the important role sleep plays in strengthening and maintaining the accuracy of a memory and hints at why the brain shuts out sensory information during periods of deep sleep. The study found that introducing new odor information to an animal while it sleeps compromises its ability to remember the difference between new and previously encountered smells while awake.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Anne Nicholas
Society for Neuroscience

Public Release: 8-Apr-2014
Alcoholism: Clinical & Experimental Research
National survey links teen binge drinking and alcohol-brand references in pop music
Binge drinking by teenagers and young adults is strongly associated with liking, owning and correctly identifying music that references alcohol by brand name, according to a study by the University of Pittsburgh and Norris Cotton Cancer Center. Based on a national, randomized survey of more than 2,500 people ages 15 to 23, the findings suggest that policy and educational interventions designed to limit the influence of alcohol-brand references in popular music could be important.
NIH/National Cancer Institute

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 8-Apr-2014
Journal of Clinical Investigation
UNC researchers find genetic trigger for RSV-induced infant hospitalizations
Researchers at UNC School of Medicine have pinpointed a viral protein that plays a major role in making respiratory syncytial virus the most common cause of hospitalization in children under one year of age.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 8-Apr-2014
Alcoholism: Clinical & Experimental Research
Chronic smoking can diminish postural stability
Chronic cigarette smoking has a high co-occurrence with alcohol use disorders. Postural instability is also common among alcohol dependent individuals. New findings indicate that chronic cigarette use continues to impact the brain systems regulating postural stability even during abstinence from alcohol.
National Institutes of Health

Contact: Thomas Paul Schmidt
415-221-4810 x3254
Alcoholism: Clinical & Experimental Research

Public Release: 8-Apr-2014
Alcoholism: Clinical & Experimental Research
Crafty alcohol advertising directed at US adolescents through music and branding
Researchers investigate links between adolescents' involvement with music and their drinking-related behaviors. Results indicate strong associations between liking, owning, and correctly identifying music containing alcohol branding and two early problematic alcohol outcomes. Study authors suggest policy or educational interventions to reduce the impact of these exposures.
NIH/National Cancer Institute

Contact: Brian A. Primack
Alcoholism: Clinical & Experimental Research

Showing releases 2901-2925 out of 3572.

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