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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 2901-2925 out of 3512.

<< < 112 | 113 | 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 > >>

Public Release: 9-Jan-2014
Journal of Biological Chemistry
LSUHSC research reveals structure of master regulator and new drug target for autism, cervical cancer
A team of scientists at LSU Health Sciences Center New Orleans has discovered the structure of the active form of E6-associated protein (E6AP), an enzyme that acts as a master regulator, controlling functions like the ability of nerve cells to "rewire" themselves in response to external stimuli and HPV hijacking cells leading to cervical cancer. They report, for the first time, that the active form of E6AP is composed of three distinct protein molecules.
National Institutes of Health

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center

Public Release: 9-Jan-2014
Blood
Red blood cells take on many-sided shape during clotting
Red blood cells are the body's true shape shifters, perhaps the most malleable of all cell types. While studying how blood clots contract researchers discovered a new geometry that red blood cells assume, when compressed during clot formation.
NIH/National Heart, Lung, and Blood Institute

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 9-Jan-2014
Neuron
SHY hypothesis explains that sleep is the price we pay for learning
Why do animals ranging from fruit flies to humans all need to sleep? After all, sleep disconnects them from their environment, puts them at risk and keeps them from seeking food or mates for large parts of the day.
NIH/National Institute of Mental Health

Contact: Susan Lampert Smith
ssmith5@uwhealth.org
608-890-5643
University of Wisconsin-Madison

Public Release: 9-Jan-2014
Journal of Endocrinology and Metabolism
Minorities and poor have more advanced thyroid cancers when diagnosed, UCLA study shows
UCLA researchers have found that minority patients and those of lower socioeconomic status are far more likely to have advanced thyroid cancer when they are diagnosed with the disease than white patients and those in higher economic brackets. In one of the most comprehensive studies of its kind, the UCLA team looked at nearly 26,000 patients with well-differentiated thyroid cancer and analyzed the impact of race and socioeconomic factors on the stage of presentation, as well as patient survival rates.
National Institutes of Health, Clinical Translational and Science Institute

Contact: Rachel Champeau
rchampeau@mednet.ucla.edu
310-794-2270
University of California - Los Angeles Health Sciences

Public Release: 9-Jan-2014
Science
Spinal cord findings could help explain origins of limb control
Northwestern University researchers have found that the spinal cord circuits that produce body bending in swimming fish are more complicated than previously thought. In a study of zebrafish, they report that differential control of an animal's musculature -- the basic template for controlling more complex limbs, such as in humans -- is already in place in the spinal networks of simple fish. The data could help clarify how vertebrates made the transition from water to land.
National Institutes of Health, Alfred P. Sloan Foundation, Esther A. and Joseph Klingenstein Fund

Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University

Public Release: 9-Jan-2014
Neuro-Oncology
Scientists uncover new target for brain cancer treatment
A new study is giving researchers hope that novel targeted therapies can be developed for glioblastoma multiforme, the most common and most aggressive form of brain cancer, after demonstrating for the first time that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) is a driving force behind the disease's aggressive and invasive nature.
National Institutes of Health, NIH/National Cancer Institute

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University

Public Release: 9-Jan-2014
Physical Biology
Researchers develop test to predict early onset of heart attacks
A new "fluid biopsy" technique that could identify patients at high risk of a heart attack by identifying specific cells as markers in the bloodstream has been developed by a group of researchers at the Scripps Research Institute.
NIH/National Center for Research Resources, NIH/National Cancer Institute

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 9-Jan-2014
Cell Reports
A new pathway for neuron repair is discovered
A brand-new pathway for neuron repair has been discovered that could have implications for faster and improved healing after nerve damage. The research demonstrates, for the first time, that dendrites, the component of nerve cells that receive information from the brain, have the capacity to regrow after an injury.
National Institutes of Health, Pew Charitable Trusts

Contact: Barbara K.Kennedy
science@psu.edu
814-863-4682
Penn State

Public Release: 9-Jan-2014
Developmental Cell
Mystery solved: How nerve impulse generators get where they need to go
Scientists have solved a longstanding mystery of the central nervous system, showing how a key protein gets to the right spot to launch electrical impulses that enable communication of nerve signals to and from the brain.
National Institutes of Health, NIH/National Institute of Neurological Disorders and Stroke

Contact: Chen Gu
Gu.49@osu.edu
614-292-0349
Ohio State University

Public Release: 9-Jan-2014
PLOS Pathogens
UNC research demonstrates 'guided missile' strategy to kill hidden HIV
Researchers at the UNC School of Medicine have deployed a potential new weapon against HIV -- a combination therapy that targets HIV-infected cells that standard therapies cannot kill.
National Institutes of Health

Contact: Lisa Chensvold
lisa_chensvold@med.unc.edu
919-843-5719
University of North Carolina Health Care

Public Release: 9-Jan-2014
American Journal of Transplantation
Mass. General research could expand availability of hand, face transplants
Massachusetts General Hospital investigators have made an important step towards greater availability of hand transplants, face transplants and other transplants involving multiple types of tissue. In their report in the American Journal of Transplantation, the team describes how a procedure developed at the MGH to induce immune tolerance to organ transplants also induces tolerance to a model limb transplant in miniature swine.
National Institutes of Health, Musculoskeletal Transplant Foundation, Melina Nakos Foundation

Contact: Kristen Chadwick
kschadwick@partners.org
617-643-3907
Massachusetts General Hospital

Public Release: 9-Jan-2014
Journal of Clinical Investigation
Mice exposed to retinoid deficiency in utero exhibit bronchial hyperresponsiveness as adults
In this issue of the Journal of Clinical Investigation, Wellington Cardoso and colleagues at the Boston University School of Medicine reveal that mice born to mothers with retinoid deficiency during pregnancy are at increased risk of developing airway hyperesponsiveness.
National Institutes of Health

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 9-Jan-2014
Journal of Clinical Investigation
Engineered anti-toxin antibodies improve efficacy
In this issue of the Journal of Clinical Investigation, Jeffrey Ravetch and colleagues at the Rockefeller University demonstrate that engineering the Fc domain of anti-toxin antibodies increases toxin neutralization activity through enhancing the interaction between toxin-targeting antibodies and the Fc receptor on immune cells.
National Institutes of Health, Northeast Biodefense Center

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 8-Jan-2014
Journal of Cerebral Blood Flow and Metabolism
Discovery leads to patent for novel method of treating traumatic brain injury
Dr. James Lechleiter of the UT Health Science Center at San Antonio received a US patent for his discovery that a class of compounds is protective against traumatic brain injury (TBI). Dr. Lechleiter found that two compounds stimulate the ability of the brain's caretaker cells (called astrocytes) to do their job, which includes reducing swelling. It is hoped that preliminary studies will lead to a new class of safe and effective drugs for TBI.
NIH/National Institute on Aging

Contact: Will Sansom
sansom@uthscsa.edu
210-567-2579
University of Texas Health Science Center at San Antonio

Public Release: 8-Jan-2014
AIDS Care
Study identifies risk factors for non-fatal overdoses
Researchers from Boston University School of Medicine and Boston Medical Center have identified that injection frequency and taking anti-retroviral therapy for HIV are risk factors for nonfatal drug overdoses among Russians who are HIV positive and inject drugs.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Jenny Eriksen
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center

Public Release: 8-Jan-2014
Journal of Neuroscience
Nociceptin: Nature's balm for the stressed brain
Collaborating scientists at the Scripps Research Institute, the National Institutes of Health and the University of Camerino in Italy have published new findings on a system in the brain that naturally moderates the effects of stress. The findings confirm the importance of this stress-damping system, known as the nociceptin system, as a potential target for therapies against anxiety disorders and other stress-related conditions.
National Institutes of Health, Pearson Center for Alcoholism & Addiction Research, German Research Foundation

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 8-Jan-2014
JAMA Psychiatry
Mental disorders in mid-life and older adulthood more prevalent than previously reported
Common methods of assessing mental or physical disorders may consistently underestimate the prevalence of mental disorders among middle-aged and older adults, a new study from the Johns Hopkins Bloomberg School of Public Health has found. The analysis reveals substantial discrepancies among mid-life and late-life adults in reporting past mental health disorders, including depression, compared with physical disorders such as arthritis and hypertension.
NIH/National Institute on Drug Abuse, NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Tim Parsons
tmparson@jhsph.edu
410-955-7619
Johns Hopkins University Bloomberg School of Public Health

Public Release: 8-Jan-2014
MARC travel awards announced for the APS 2014 Professional Skills Training Course
THe FASEB MARC (Maximizing Access to Research Careers) Program has announced the travel award recipients for the American Physiological Society Professional Skills Training Course in Orlando, Fla., from Jan. 16-19, 2014.
National Institutes of Health

Contact: Gail Pinder
gpinder@faseb.org
301-634-7021
Federation of American Societies for Experimental Biology

Public Release: 8-Jan-2014
Proceedings of the Royal Society B
Coral chemical warfare: Suppressing a competitor enhances susceptibility to a predator
Competition may have a high cost for at least one species of tropical seaweed. Researchers examining the chemical warfare taking place on Fijian coral reefs have found that one species of seaweed increases its production of noxious anti-coral compounds when placed into contact with reef-building corals, but at the same time becomes more attractive to herbivorous fish.
National Science Foundation, National Institutes of Health

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology

Public Release: 8-Jan-2014
Journal of Experimental Psychology: General
Infants show ability to tell friends from foes
Even before babies have language skills or much information about social structures, they can infer whether other people are likely to be friends by observing their likes and dislikes, a new study on infant cognition has found.
National Institutes of Health, National Science Foundation

Contact: Jann Ingmire
jingmire@uchicago.edu
773-702-2772
University of Chicago

Public Release: 8-Jan-2014
Science Translational Medicine
Bio-inspired glue keeps hearts securely sealed
In the preclinical study, researchers from Boston Children's Hospital, BWH and Massachusetts Institute of Technology developed a bio-inspired adhesive that could rapidly attach biodegradable patches inside a beating heart -- in the exact place where congenital holes in the heart occur, such as with ventricular heart defects.
Center for Integration of Medicine and Innovative Technology, National Institutes of Health

Contact: Lori J Schroth
ljschroth@partners.org
617-525-6374
Brigham and Women's Hospital

Public Release: 8-Jan-2014
Journal of Experimental Medicine
Scripps Florida scientists identify possible key to drug resistance in Crohn's disease
Scientists from the Florida campus of The Scripps Research Institute have identified a normally small subset of immune cells that may play a major role in the development of Crohn's disease generally and in disease-associated steroid resistance specifically.
National Institutes of Health, Crohns & Colitis Foundation, Crohn's & Colitis Discovery Laboratory at University of Miami

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 8-Jan-2014
Genome Biology
Penn biologists establish new method for studying RNA's regulatory 'footprint'
Biologists at the University of Pennsylvania and colleagues have teamed up to offer a new method to efficiently obtain an entire "footprint" of interactions between RNA and the proteins that bind to RNA molecules.
National Science Foundation, National Human Genome Research Institute, NIH/National Institute of General Medical Sciences

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 8-Jan-2014
Journal of Clinical Oncology
AML score that combines genetic and epigenetic changes might help guide therapy
Currently, doctors use chromosome markers and gene mutations to determine the best treatment for patients with acute myeloid leukemia. But a new study suggests that a score based on seven mutated genes and the epigenetic changes that the researchers discovered were also present might help guide treatment by identifying novel subsets of patients. Patients with a low score had the best outcomes, and those with high scores had the poorest outcomes.
NIH/National Cancer Institute, Coleman Leukemia Research Foundation, Pelotonia Fellowship Program

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 8-Jan-2014
EMBO Reports
Researchers propose alternative way to allocate science funding
Researchers in the United States have suggested an alternative way to allocate science funding. The method, which is described in EMBO reports, depends on a collective distribution of funding by the scientific community, requires only a fraction of the costs associated with the traditional peer review of grant proposals and, according to the authors, may yield comparable or even better results.
National Science Foundation, Andrew W Mellon Foundation, National Institutes of Health

Contact: Barry Whyte
barry.whyte@embo.org
EMBO

Showing releases 2901-2925 out of 3512.

<< < 112 | 113 | 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 > >>

     
   

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