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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 2901-2925 out of 3417.

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Public Release: 20-Jun-2013
Cell Reports
Pluripotent cells from pancreatic cancer cells first human model of cancer's progression
Pancreatic cancer carries a dismal prognosis. Researchers and clinicians don't have a non-invasive way to even detect early cells that portent later disease. Scientists have created a research cell line from a patient with advanced pancreatic cancer. This first-of-its-kind human-cell model of pancreatic cancer progression is the first example using induced pluripotent stem cells to model cancer progression directly from a solid tumor and to model pancreatic cancer from early to invasive stages.
NIH/National Institute for General Medical Sciences

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 20-Jun-2013
Animal study shows promising path to prevent epilepsy
Duke Medicine researchers have identified a receptor in the nervous system that may be key to preventing epilepsy following a prolonged period of seizures. Their findings from studies in mice, published online in the journal Neuron on June 20, 2013, provide a molecular target for developing drugs to prevent the onset of epilepsy, not just manage the disease's symptoms.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Rachel Harrison
Duke University Medical Center

Public Release: 19-Jun-2013
Researchers explain how neural stem cells create new and varied neurons
A new study examining the brains of fruit flies reveals a novel stem cell mechanism that may help explain how neurons form in humans. A paper on the study by researchers at the University of Oregon appeared in the online version of the journal Nature in advance of the June 27 publication date.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Lewis Taylor
University of Oregon

Public Release: 19-Jun-2013
FASEB Journal
Restoring appropriate movement to immune cells may save seriously burned patients
Patients who survive the immediate aftermath of major burns are at greatest risk from infections -- particularly the overwhelming, life-threatening immune reaction known as sepsis. A device developed by Massachusetts General Hospital investigators that measures the movement of key immune cells may help determine which patients are at greatest risk for infections, and a novel treatment that directly addresses the cause of those complications could prevent many associated deaths.
Shriners Burns Hospital, National Institutes of Health

Contact: Sue McGreevey
Massachusetts General Hospital

Public Release: 19-Jun-2013
American Journal of Clinical Nutrition
Dietary fructose causes liver damage in animal model, study finds
The role of dietary fructose in the development of obesity and fatty liver diseases remains controversial, with previous studies indicating that the problems resulted from fructose and a diet too high in calories. However, a new study conducted in an animal model at Wake Forest Baptist Medical Center showed that fructose rapidly caused liver damage even without weight gain.
National Institutes of Health

Contact: Marguerite Beck
Wake Forest Baptist Medical Center

Public Release: 19-Jun-2013
Cell Host & Microbe
A new model -- and possible treatment -- for staph bone infections
Osteomyelitis -- a debilitating bone infection most frequently caused by Staphylococcus aureus ("staph") bacteria is particularly challenging to treat. Now, Vanderbilt University investigators have identified a staph-killing compound that may be an effective treatment for osteomyelitis, and they have developed a new mouse model that will be useful for testing this compound and for generating additional therapeutic strategies.
National Institutes of Health

Contact: Leigh MacMillan
Vanderbilt University Medical Center

Public Release: 19-Jun-2013
Fate of the heart: Researchers track cellular events leading to cardiac regeneration
In a study published in the June 19 online edition of the journal Nature, a scientific team led by researchers from the University of California, San Diego School of Medicine visually monitored the dynamic cellular events that take place when cardiac regeneration occurs in zebrafish after cardiac ventricular injury. Their findings provide evidence that various cell lines in the heart are more plastic, or capable of transformation into new cell types, than previously thought.
American Heart Association, Packard Foundation, NIH/National Heart, Lung, and Blood Institute

Contact: Debra Kain
University of California - San Diego

Public Release: 19-Jun-2013
Scientists awarded $1.4 million to develop new therapeutic approaches to chronic leukemia
Scientists from the Florida campus of The Scripps Research Institute have been awarded more than $1.4 million from the National Cancer Institute of the National Institutes of Health to create a potential new drug to attack the malignant cells that cause chronic lymphocytic leukemia, the most common leukemia in the Western world.
National Institutes of Health, Lymphoma Research Foundation

Contact: Eric Sauter
Scripps Research Institute

Public Release: 19-Jun-2013
Nature Communications
Genetics of cervical cancer raise concern about antiviral therapy in some cases
A new understanding of the genetic process that can lead to cervical cancer may help improve diagnosis of potentially dangerous lesions for some women, and also raises a warning flag about the use of anti-viral therapies in certain cases -- suggesting they could actually trigger the cancer they are trying to cure.
National Institutes of Health

Contact: Andrey Morgun
Oregon State University

Public Release: 19-Jun-2013
Archives of Sexual Behavior
Why are some college students more likely to 'hook up'?
A new study by researchers with The Miriam Hospital's Centers for Behavioral and Preventive Medicine suggests there are certain factors and behaviors associated with sexual hookups, particularly among first-year college women.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Jessica Collins Grimes

Public Release: 19-Jun-2013
New England Journal of Medicine
Drug shows surprising efficacy as treatment for chronic leukemia, mantle cell lymphoma
Two clinical studies published online in the New England Journal of Medicine suggest that the novel, targeted agent ibrutinib shows real potential is a safe, effective, treatment for adults with chronic lymphocytic leukemia and for patients with mantle cell lymphoma.
Pharmacyclics, Inc.; Leukemia and Lymphoma Society; NIH/National Cancer Institute; D. Warren Brown Foundation

Contact: Liz Bryan
Ohio State University Wexner Medical Center

Public Release: 19-Jun-2013
Science Translational Medicine
A shot in the arm for old antibiotics
Slipping bacteria some silver could give old antibiotics new life, scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University reported June 19 in Science Translational Medicine. This could pave the way for new therapies for drug-resistant and recurrent infections.
National Institutes of Health, Howard Hughes Medical Institute, Wyss Institute for Biologically Inspired Engineering

Contact: Dan Ferber
Wyss Institute for Biologically Inspired Engineering at Harvard

Public Release: 19-Jun-2013
Moffitt Cancer Center researchers identify genetic variants predicting aggressive prostate cancers
Researchers at Moffitt Cancer Center and colleagues at Louisiana State University have developed a method for identifying aggressive prostate cancers that require immediate therapy. It relies on understanding the genetic interaction between single nucleotide polymorphisms. The goal is to better predict a prostate cancer's aggressiveness to avoid unnecessary radical treatment.
American Cancer Society, NIH/National Cancer Institute

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 19-Jun-2013
American Journal of Physiology - Endocrinology and Metabolism
Breakthrough research of essential molecule reveals important targets in diabetes and obesity
A research team led by Assia Shisheva, Ph.D., professor of physiology in Wayne State University's School of Medicine, has made breakthrough advancements on a molecule that may provide more answers to the mystery of the molecular mechanisms by which insulin regulates glucose uptake in fat and muscle cells.
National Institutes of Health, Wayne State University, American Diabetes Association

Contact: Julie O'Connor
Wayne State University - Office of the Vice President for Research

Public Release: 19-Jun-2013
Annals of Neurology
Staging system in ALS shows potential tracks of disease progression, Penn study finds
The motor neuron disease Amyotrophic lateral sclerosis, also known as Lou Gehrig's Disease, progresses in a stepwise, sequential pattern which can be classified into four distinct stages, report pathologists with the Perelman School of Medicine at the University of Pennsylvania in the Annals of Neurology.
National Institutes of Health, Wyncote Foundation, Koller Family Foundation, Deutsche Forschungsgeme

Contact: Kim Menard
University of Pennsylvania School of Medicine

Public Release: 19-Jun-2013
Brain re-training may improve memory, focus in schizophrenia
Much like physical exercise can re-chisel the body, researchers hope targeted mental workouts can sharpen the memory, focus and function of adults with schizophrenia.
NIH/National Institute of Mental Health

Contact: Toni Baker
Medical College of Georgia at Georgia Regents University

Public Release: 19-Jun-2013
ACS Nano
Sound waves precisely position nanowires
The smaller components become, the more difficult it is to create patterns in an economical and reproducible way, according to an interdisciplinary team of Penn State researchers who, using sound waves, can place nanowires in repeatable patterns for potential use in a variety of sensors, optoelectronics and nanoscale circuits.
National Institutes of Health, National Science Foundation

Contact: A'ndrea Elyse Messer
Penn State

Public Release: 19-Jun-2013
Nature Genetics
New research backs theory that genetic 'switches' play big role in human evolution
A Cornell University study offers further proof that the divergence of humans from chimpanzees some 4 million to 6 million years ago was profoundly influenced by mutations to DNA sequences that play roles in turning genes on and off.
The Packard Foundation, Alfred P. Sloan Foundation, National Science Foundation, National Institutes of Health

Contact: John Carberry
Cornell University

Public Release: 19-Jun-2013
What do memories look like?
Scientists develop a way to see the structures that store memories in a living brain.
National Institutes of Health

Contact: Robert Perkins
University of Southern California

Public Release: 19-Jun-2013
Genetic 'off switch' linked to increased risk factors for heart disease
People with a gene that has been turned off through a natural process maybe at higher risk of heart and blood-vessel disease. The affected gene, called CPT1A, makes a liver enzyme which, at low levels, is linked to increased risk factors for heart and blood-vessel disease. Evaluating CPT1A as a new genetic biomarker may one day identify people at the greatest risk for developing heart disease.
National Institutes of Health

Contact: Maggie Francis
American Heart Association

Public Release: 19-Jun-2013
Laughing gas does not increase heart attacks
Nitrous oxide (laughing gas) is one of the world's oldest and most widely used anesthetics, but concerns that it raises the risk of a heart attack during surgery or soon afterward are unfounded, according to a new study from researchers at Washington University School of Medicine in St. Louis.
National Institutes of Health, Foundation for Anesthesia Education and Research

Contact: Jim Dryden
Washington University School of Medicine

Public Release: 19-Jun-2013
Biologists identify the chemical behind cancer resistance in naked mole rats
Two researchers at the University of Rochester have discovered the chemical that makes naked mole rats cancer-proof.
National Institutes of Health, Ellison Medical Foundation

Contact: Peter Iglinski
University of Rochester

Public Release: 19-Jun-2013
Carnegie Mellon researchers identify emotions based on brain activity
For the first time, scientists at Carnegie Mellon University have identified which emotion a person is experiencing based on brain activity. The study combines functional magnetic resonance imaging and machine learning to measure brain signals to accurately read emotions in individuals. The findings illustrate how the brain categorizes feelings, giving researchers the first reliable process to analyze emotions. Until now, research on emotions has been long stymied by the lack of reliable methods to evaluate them.
NIH/National Institute of Mental Health

Contact: Shilo Rea
Carnegie Mellon University

Public Release: 19-Jun-2013
Scientists find new source of versatility so 'floppy' proteins can get things done
Many proteins work like Swiss Army knives, fitting multiple functions into their elaborately folded structures. A bit mysteriously, some proteins manage to multitask even with structures that are unfolded and floppy -- "intrinsically disordered." In this week's issue of Nature, scientists at The Scripps Research Institute report their discovery of an important trick that a well-known intrinsically disordered protein uses to expand and control its functionality.
National Institutes of Health, Skaggs Institute for Chemical Biology at Scripps Research Institute

Contact: Mika Ono
Scripps Research Institute

Public Release: 19-Jun-2013
1 in 4 stroke patients suffer PTSD
One in four people who survive a stroke or transient ischemic attack (TIA) suffer from symptoms of PTSD within the first year post-event, and one in nine experience chronic PTSD more than a year later. The data suggest that each year nearly 300,000 stroke/TIA survivors will develop PTSD symptoms as a result of their health scare. The study, led by Columbia University Medical Center researchers, was published today in the online edition of PLOS ONE.
National Institutes of Health

Contact: Elizabeth Streich
Columbia University Medical Center

Showing releases 2901-2925 out of 3417.

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