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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 2901-2925 out of 3402.

<< < 112 | 113 | 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 > >>

Public Release: 16-Jun-2013
ENDO 2013
Drug boosts fat tissue's calorie-burning ability in lab
A drug that mimics the activity of thyroid hormone significantly increases the amount of energy burned by fat tissue and promotes weight loss, an animal study of metabolism finds. The results were presented Sunday at The Endocrine Society's 95th Annual Meeting in San Francisco.
National Institutes of Health

Contact: Jenni Glenn Gingery
jgingery@endocrine.org
301-941-0240
The Endocrine Society

Public Release: 16-Jun-2013
Nature
The Rett Syndrome protein surrenders some of its secrets
Discovery of a mutant gene responsible for a disease is a milestone, but for most conditions, it may be only a first step towards a treatment or cure. Understanding Rett Syndrome, an autism spectrum disorder, is further complicated by the fact that the implicated gene controls a suite of other genes. Two papers, published in today's Nature Neuroscience and Nature, reveal key steps in how mutations in the gene for methyl CpG-binding protein cause the condition.
Rett Syndrome Research Trust, Wellcome Trust, National Institutes of Health

Contact: Monica Coenraads
monica@rsrt.org
203-445-0041
Rett Syndrome Research Trust

Public Release: 14-Jun-2013
Journal of the American Heart Association
Sugar overload can damage heart according to UTHealth research
Too much sugar can set people down a pathway to heart failure, according to a study led by researchers at The University of Texas Health Science Center at Houston.
National Institutes of Health

Contact: Deborah Lake
deborah.m.lake@uth.tmc.edu
713-500-3304
University of Texas Health Science Center at Houston

Public Release: 14-Jun-2013
PLOS ONE
Penn Researchers design variant of main painkiller receptor
An interdisciplinary collaboration between researchers at the University of Pennsylvania has developed a variant of the mu opioid receptor that has several advantages when it comes to experimentation. This variant can be grown in large quantities in bacteria and is also water-soluble, enabling experiments and applications that had previously been very challenging or impossible.
National Science Foundation, National Institutes of Health, Foundation for Anesthesia Education and Research, Groff Foundation

Contact: Evan Lerner
elerner@upenn.edu
215-573-6604
University of Pennsylvania

Public Release: 14-Jun-2013
Cancer Research
Developmental protein plays role in spread of cancer
A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center in the June 15, 2013 issue of the journal Cancer Research.
National Institutes of Health, California Institute of Regenerative Medicine, Blood Cancer Research Fund

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 14-Jun-2013
PLOS ONE
Stress test and brain scans pinpoint 2 distinct forms of Gulf War illness
New research suggests that Gulf War illness may have two distinct forms depending on which brain regions have atrophied. In a study of Gulf War veterans, Georgetown researchers say their findings help explain why clinicians have consistently encountered veterans with different symptoms and complaints.
US Department of Defense, National Institutes of Health

Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 13-Jun-2013
Journal of Neurotrauma
Testing method promising for spinal cord injuries, multiple sclerosis
A medical test previously developed to measure a toxin found in tobacco smokers has been adapted to measure the same toxin in people suffering from spinal cord injuries and multiple sclerosis, offering a potential tool to reduce symptoms.
National Institutes of Health

Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University

Public Release: 13-Jun-2013
Proceedings of the National Academy of Sciences
Metabolic molecule drives growth of aggressive brain cancer
A new study has identified an abnormal metabolic pathway that drives cancer-cell growth in a particular subtype of glioblastoma, the most common and lethal form of brain cancer. The finding could lead to new therapies for a subset of patients with glioblastoma.
ACS, NIH/National Cancer Institute, NIH/National Institute of General Medical Sciences

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 13-Jun-2013
Journal of Chromotography B
Monell-led research identifies scent of melanoma
Monell researchers identified odorants from human skin cells that can be used to identify melanoma, the deadliest form of skin cancer. In addition, a nanotechnology-based sensor could utilize the odor profiles to reliably differentiate melanoma cells from normal skin cells. Non-invasive odor analysis may be a valuable technique in the detection and early diagnosis of human melanoma.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Leslie Stein
stein@monell.org
267-519-4707
Monell Chemical Senses Center

Public Release: 13-Jun-2013
American Journal of Public Health
Tobacco laws for youth may reduce adult smoking
States that want to reduce rates of adult smoking may consider implementing stringent tobacco restrictions on teens. Washington University researchers discovered that states with more restrictive limits on teens purchasing tobacco also have lower adult smoking rates, especially among women.
NIH/National Institute on Drug Abuse, NIH/National Cancer Institute, American Cancer Society

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine

Public Release: 13-Jun-2013
American Journal of Human Genetics
Yale researchers unravel genetics of dyslexia and language impairment
A new study of the genetic origins of dyslexia and other learning disabilities could allow for earlier diagnoses and more successful interventions, according to researchers at Yale School of Medicine. Many students now are not diagnosed until high school, at which point treatments are less effective.
Wellcome Trust, National Institutes of Health

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University

Public Release: 13-Jun-2013
American Journal of Public Health
Farmworkers feel the heat even when they leave the fields
Wake Forest Baptist Medical Center researchers conducted a study to evaluate the heat indexes in migrant farmworker housing and found that a majority of the workers don't get a break from the heat when they're off the clock.
NIH/National Institute of Environmental Health Sciences

Contact: Bonnie Davis
bdavis@wakehealth.edu
336-716-4977
Wake Forest Baptist Medical Center

Public Release: 13-Jun-2013
Cardiovascular Research
Gene offers an athlete's heart without the exercise
Researchers at Case Western Reserve University have found that a single gene poses a double threat to disease: Not only does it inhibit the growth and spread of breast tumors, but it also makes hearts healthier. In 2012, medical school researchers discovered the suppressive effects of the gene HEXIM1 on breast cancer in mouse models. Now they have demonstrated that it also enhances the number and density of blood vessels in the heart.
American Heart Association, National Institutes of Health, American Recovery & Reinvestment Act

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University

Public Release: 13-Jun-2013
Stem Cells
Researchers gain new molecular-level understanding of the brain's recovery after stroke
A specific MicroRNA, a short set of RNA (ribonuclease) sequences, naturally packaged into minute (50 nanometers) lipid containers called exosomes, are released by stem cells after a stroke and contribute to better neurological recovery according to a new animal study by Henry Ford Hospital researchers. This study provides fundamental new insight into how stem cells affect injured tissue and also offers hope for developing novel treatments for stroke and neurological diseases, the leading cause of long-term disability in adult humans.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute on Aging

Contact: Dwight Angell
dwight.angell@hfhs.org
313-850-3471
Henry Ford Health System

Public Release: 13-Jun-2013
American Journal of Sports Medicine
After an ACL tear: Research opens door to new treatments to improve recovery for athletes
New drug target may prevent one of the most dreaded consequences of an ACL tear.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Beata Mostafavi
bmostafa@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 13-Jun-2013
Science
Study: Context crucial when it comes to mutations in genetic evolution
New research led by evolutionary biologist Jay Storz of the University of Nebraska-Lincoln has found that whether a given mutation is good or bad is often determined by other mutations associated with it. In other words, genetic evolution is context-dependent.
National Institutes of Health, National Science Foundation

Contact: Jay Storz
jstorz2@unl.edu
402-450-9057
University of Nebraska-Lincoln

Public Release: 13-Jun-2013
American Journal of Public Health
Universal paid sick leave reduces spread of flu, according to Pitt simulation
Allowing all employees access to paid sick days would reduce influenza infections in the workplace by nearly 6 percent, according to a first-of-its-kind analysis by University of Pittsburgh Graduate School of Public Health modeling experts. The researchers simulated an influenza epidemic in Pittsburgh and surrounding Allegheny County and estimated it to be more effective for small, compared to large, workplaces. The results are reported in the American Journal of Public Health.
NIH/National Institute of General Medical Sciences

Contact: Allison Hydzik
hydzikam@upmc.edu
412-647-9975
University of Pittsburgh Schools of the Health Sciences

Public Release: 13-Jun-2013
Psychology and Aging
Volunteering reduces risk of hypertension in older adults, Carnegie Mellon research shows
It turns out that helping others can also help you protect yourself from high blood pressure. New shows that older adults who volunteer for at least 200 hours per year decrease their risk of hypertension, or high blood pressure, by 40 percent. The study suggests that volunteer work may be an effective non-pharmaceutical option to help prevent the condition. Hypertension affects an estimated 65 million Americans and is a major contributor to cardiovascular disease.
NIH/National Institute on Aging, National Center for Complementary and Alternative Medicine

Contact: Shilo Rea
shilo@cmu.edu
412-268-6094
Carnegie Mellon University

Public Release: 13-Jun-2013
Cancer Cell
Protein protects against breast cancer recurrence in animal model
Precisely what causes breast cancer recurrence has been poorly understood. But now a piece of the puzzle has fallen into place: Researchers at the Perelman School of Medicine, University of Pennsylvania have identified a key molecular player in recurrent breast cancer -- a finding that suggests potential new therapeutic strategies.
NIH/National Cancer Institute, Department of Defense Breast Cancer Research Program, Breast Cancer Research Foundation

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 13-Jun-2013
Alcoholism: Clinical & Experimental Research
Could novel drug target autism and fetal alcohol disorder?
A surprising new study reveals a common molecular vulnerability in autism and fetal alcohol disorder. Both have social impairment symptoms and originate during brain development. The study found male offspring of rat mothers given alcohol during pregnancy have social impairment and altered levels of autism-related genes found in humans. But the damage was reversed with a thyroid hormone given to the mothers during pregnancy.
NIH/National Institute of Alcohol Abuse and Alcoholism

Contact: Marla Paul
marla-paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 13-Jun-2013
Science
Gustatory tug-of-war key to whether salty foods taste good
As anyone who's ever mixed up the sugar and salt while baking knows, too much of a good thing can be inedible. What hasn't been clear, though, is how our tongues and brains can tell when the saltiness of our food has crossed the line from yummy to yucky -- or, worse, something dangerous. Now researchers at the Johns Hopkins University School of Medicine and the University of California, Santa Barbara report that in fruit flies, at least, that process is controlled by competing input from two different types of taste-sensing cells: one that attracts flies to salty foods, and one that repels them.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Public Release: 13-Jun-2013
Cancer Discovery
Genetic variations may help identify best candidates for preventive breast cancer drugs
Newly discovered genetic variations may help predict breast cancer risk in women who receive preventive breast cancer therapy with the selective estrogen receptor modulator drugs tamoxifen and raloxifene, a Mayo Clinic-led study has found. The study is published in the journal Cancer Discovery.
NIH/National Institute of General Medical Science

Contact: Joe Dangor
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

Public Release: 13-Jun-2013
Alcoholism: Clinical & Experimental Research
Certain environmental factors impact alcohol problems more for European than African-American women
An early age at first drink (AFD) is associated with a greater risk for subsequent alcohol use disorders. A new study looks at the influences of genetics versus the environment on AFD and problem drinking among African American (AA) and European American (EA) women. Findings indicate that environmental factors play a larger role in the development of alcohol-related problems in EA than AA women.
NIH/National Institute on Alcohol Abuse and Alcoholism, NIH/National Institute of Child Health and Human Development

Contact: Carolyn E. Sartor
carolyn.sartor@yale.edu
203-932-5711
Alcoholism: Clinical & Experimental Research

Public Release: 13-Jun-2013
Alcoholism: Clinical & Experimental Research
Fetal alcohol spectrum disorders and autism spectrum disorder share common molecular vulnerabilities
Both fetal alcohol spectrum disorders and autism spectrum disorder are neurodevelopmental in origin. A new rodent study has found that these disorders share common molecular vulnerabilities. Findings also suggest that a low dose of the thyroid hormone thyroxin to the pregnant mothers appears to alleviate some of the effects of alcohol exposure on their offspring.
National Institutes of Health

Contact: Eva E. Redei
e-redei@northwestern.edu
312-908-1791
Alcoholism: Clinical & Experimental Research

Public Release: 13-Jun-2013
Alcoholism: Clinical & Experimental Research
Chronic drinking + exposure to particulate matter dramatically decreases lung function
Alveolar macrophage (AM) function plays a critical role in protecting the lungs by removing particulates. Chronic drinking causes persistent oxidative stress in the lungs, leading to impaired AM function. A new rodent study shows that chronic drinking appears to intensify lung damage caused by particulate matter.
NIH/National Institute on Alcohol Abuse and Alcoholism, Louisiana State Board of Regents

Contact: Stephania A. Cormier
scorm1@lsuhsc.edu
504-568-2810
Alcoholism: Clinical & Experimental Research

Showing releases 2901-2925 out of 3402.

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