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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 2901-2925 out of 3493.

<< < 112 | 113 | 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 > >>

Public Release: 19-Dec-2013
PLOS Pathogens
Biologists find clues to a parasite's inconsistency
MIT researchers find that certain strains of Toxoplasma provoke inflammation that can damage host cells, while others are harmless.
New England Regional Center of Excellence, Pew Scholars Program in the Biomedical Sciences, Robert A. Swanson Career Development Award, Knights Templar Eye Foundation, Wellcome Trust Foundation, National Institutes of Health

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Public Release: 19-Dec-2013
Cell Stem Cell
Brain repair after injury and Alzheimer's disease
Scientists at Penn State University have developed an innovative technology to regenerate functional neurons after brain injury. The technology may be developed into a new therapeutic treatment for traumatic brain and spinal cord injuries, stroke, Alzheimer's disease, Parkinson's disease, and other neurological disorders.
National Institutes of Health, Penn State University Eberly College of Science

Contact: Barbara K. Kennedy
science@psu.edu
81-488-634-682
Penn State

Public Release: 19-Dec-2013
PLOS Genetics
Protein links liver cancer with obesity, alcoholism, and hepatitis
A new study identifies an unexpected molecular link between liver cancer, cellular stress, and risk factors for developing this cancer -- obesity, alcoholism, and viral hepatitis. The study by University of Iowa researchers shows that a protein called CHOP, which had previously been thought to generally protect against cancer, actually promotes liver cancer in mice and may do the same in humans. The findings are published Dec. 19 in the journal PLOS Genetics.
NIH/National Institute of Diabetes, Digestive, and Kidney Disorders

Contact: Jennifer Brown
jennifer-l-brown@uiowa.edu
319-356-7124
University of Iowa Health Care

Public Release: 19-Dec-2013
Nature
Gladstone scientists discover how immune cells die during HIV infection; identify potential drug to block AIDS
Research led by scientists at the Gladstone Institutes has identified the chain of molecular events that drives the death of the immune system's CD4 T cells as an HIV infection leads to AIDS. Further, they have identified an existing anti-inflammatory drug that blocks the death of these cells -- and now are planning a Phase 2 clinical trial to determine if it can prevent HIV-infected people from developing AIDS.
National Institutes of Health, A.P. Giannini Postdoctoral Research Fellowship, University of California San Francisco/Robert John Sabo Trust Award

Contact: Anne Holden
anne.holden@gladstone.ucsf.edu
415-734-2534
Gladstone Institutes

Public Release: 19-Dec-2013
Stroke: Journal of the American Heart Association
Anxiety linked to higher long-term risk of stroke
This is the first study to link anxiety to a greater risk of stroke.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute of Mental Health

Contact: Darcy Spitz
darcy.spitz@heart.org
212-878-5940
American Heart Association

Public Release: 19-Dec-2013
Science
Team finds new way to map important drug targets
Researchers have used new techniques and one of the brightest X-ray sources on the planet to map the 3-D structure of an important cellular gatekeeper in a more natural state than possible before.
National Institutes of Health, National Science Foundation

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 19-Dec-2013
PLOS Genetics
Stowers researchers announce first genetic model of a human jaw fusion defect known as syngnathia
The face you critiqued in the mirror this morning was sculpted before you were born by a transient population of cells called neural crest cells. Those cells spring from neural tissue of the brain and embryonic spinal cord and travel throughout the body, where they morph into highly specialized bone structures, cartilage, connective tissue, and nerve cells.
NIH/National Institute of Dental and Craniofacial Research, March of Dimes, and others

Contact: Gina Kirchweger
gxk@stowers.org
816-806-1036
Stowers Institute for Medical Research

Public Release: 19-Dec-2013
Cell
A new -- and reversible -- cause of aging
Researchers have discovered a cause of aging in mammals involving a series of molecular events that disables communication between the nucleus and mitochondria. By administering a molecule naturally produced by the human body, the communication network was restored in older mice. Subsequent tissue samples showed biological hallmarks comparable to much younger animals.
NIH/National Institute on Aging, Glenn Foundation for Medical Research, and others

Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School

Public Release: 19-Dec-2013
Science
Cocaine, meth response differ between 2 substrains of 'Black 6' laboratory mouse
Researchers including Jackson Laboratory Professor Gary Churchill, Ph.D., have found a single nucleotide polymorphism difference in cocaine and methamphetamine response between two substrains of the C57BL/6 or "Black 6" inbred laboratory mouse, pointing to Cyfip2 as a regulator of cocaine response with a possible role in addiction.
NIH/National Institute on Drug Abuse

Contact: Joyce Peterson
joyce.peterson@jax.org
207-288-6058
Jackson Laboratory

Public Release: 19-Dec-2013
Science
Gene transfer gone wild reveals driving force behind mitochondrial sex
Pioneering research led by Indiana University has identified genes from a number of plant species, including the entire mitochondrial genomes from three green algae and one moss, in the mitochondrial genome of Amborella trichopoda. The South Pacific shrub is considered to be the sole survivor -- the "last man standing" -- of one of the two oldest lineages of flowering plants, while the other lineage comprises the other 300,000 species of flowering plants.
National Institutes of Health, National Science Foundation, US Department of Energy

Contact: Stephen Chaplin
stjchap@iu.edu
812-856-1896
Indiana University

Public Release: 18-Dec-2013
Stem Cells
Stem cells offer clues to reversing receding hairlines
Regenerative medicine may offer ways to banish baldness that don't involve toupees. The lab of USC scientist Krzysztof Kobielak, M.D., Ph.D., has published a trio of papers in the journals Stem Cells and The Proceedings of the National Academy of Sciences that describe some of the factors that determine when hair grows, when it stops growing and when it falls out.
National Institutes of Health, California Institute for Regenerative Medicine

Contact: Cristy Lytal
lytal@med.usc.edu
University of Southern California - Health Sciences

Public Release: 18-Dec-2013
Fatigue, a common side effect of breast cancer treatment, evaluated in novel patient study
Although the prevalence and impact of cancer-related fatigue has been well established, very little is known about its predictors, mechanisms for development, and persistence post-treatment. A new research study at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, in partnership with UCLA, is aimed at identifying breast cancer patients most susceptible to post-treatment fatigue by measuring biological, behavioral and social risk factors.
National Institutes of Health

Contact: Cara Martinez
cara.martinez@cshs.org
310-423-7798
Cedars-Sinai Medical Center

Public Release: 18-Dec-2013
Journal of Clinical Investigation
Role for sugar uptake in breast cancer revealed
Berkeley Lab researchers have shown that aerobic glycolysis -- glucose metabolism in the presence of oxygen -- is not the consequence of the cancerous activity of malignant cells, as has been widely believed, but is itself a cancerous event.
NIH/National Cancer Institute

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory

Public Release: 18-Dec-2013
Nature
Neanderthal genome shows early human interbreeding, inbreeding
A team that includes UC Berkeley population geneticists has produced the first high-quality genome of a Neanderthal, allowing comparison with the genomes of modern humans and Denisovans. The analysis shows a long history of interbreeding among these early humans and a fourth, previously unknown group. The Neanderthal, from Denisova cave, also shows evidence of inbreeding. About 87 genes in modern humans were found to be significantly different from related genes in Neanderthals and Denisovans.
National Institutes of Health

Contact: Robert Sanders
rlsanders@berkeley.edu
510-643-6998
University of California - Berkeley

Public Release: 18-Dec-2013
Nature Communications
Going against the flow: Halting atherosclerosis by targeting micro RNA
Researchers at Emory and Georgia Tech have developed a potential treatment for atherosclerosis that targets a master controller of the process.
NIH/National Heart, Lung and Blood Institute

Contact: Quinn Eastman
qeastma@emory.edu
404-727-7829
Emory Health Sciences

Public Release: 18-Dec-2013
JAHA: Journal of the American Heart Association
Heart disease linked with dementia in older postmenopausal women
Heart disease is linked with decreased brain function in older postmenopausal women. Women who have high blood pressure or diabetes may be at higher risk for decreasing brain function over time.
National Institutes of Health

Contact: Bridgette McNeill
bridgette.mcneill@heart.org
214-706-1135
American Heart Association

Public Release: 18-Dec-2013
JAMA Psychiatry
Markers of inflammation in the blood linked to aggressive behaviors
People with intermittent explosive disorder -- a psychiatric illness characterized by impulsivity, hostility and recurrent aggressive outbursts -- have elevated levels of two markers of systemic inflammation in their blood. The study documents a direct relationship between inflammatory markers and impulsive aggression that is not seen in people in good mental health or with other psychiatric disorders.
NIH/National Institute of Mental Health, University of Colorado, Denver

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Public Release: 18-Dec-2013
Neuron
Brain area attacked by Alzheimer's links learning and rewards
One of the first areas of the brain to be attacked by Alzheimer's disease, the posterior cingulate cortex, or PCC, has been found to step in during a cognitive challenge to improve the brain's performance. This small study in monkeys establishes a role for the PCC in learning and its connection to the brain's reward system.
National Institutes of Health

Contact: Karl Leif Bates
karl.bates@duke.edu
919-681-8054
Duke University

Public Release: 18-Dec-2013
PLOS ONE
Stress reaction gene linked to death, heart attacks
A genetic trait known to make some people especially sensitive to stress also appears to be responsible for a 38 percent increased risk of heart attack or death in patients with heart disease, scientists at Duke Medicine report.
NIH/National, Heart, Lung, and Blood Institute

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

Public Release: 18-Dec-2013
Science Translational Medicine
Newly identified immune receptor may activate B cells in autoimmunity
A newly identified immune protein influences each person's response to vaccines and risk for autoimmune diseases like lupus and multiple sclerosis. The protein, called a receptor and part of signaling pathways, also provides a new target for personalized therapies for patients with autoimmune diseases.
National Institutes of Health, American College of Rheumatology

Contact: Greg Williams
gdw@uab.edu
205-721-0710
University of Alabama at Birmingham

Public Release: 18-Dec-2013
PLOS ONE
No link between HIV-prevention pill Truvada and increased sexual risk behavior
In 2012 the HIV antiretroviral drug Truvada became the first and only medication approved by the FDA for HIV prevention. Led by Gladstone Institutes' Investigator Robert Grant, M.D., M.P.H., this research was hailed as an important step towards reducing the worldwide HIV/AIDS epidemic. Now, a new study provides further proof that regular Truvada use can reduce one's risk for contracting HIV -- without increasing sexual risk behavior.
National Institutes of Health, Bill and Melinda Gates Foundation

Contact: Anne Holden
anne.holden@gladstone.ucsf.edu
415-734-2534
Gladstone Institutes

Public Release: 17-Dec-2013
Stem Cells
Muscle-invasive and non-muscle invasive bladder cancers arise from different stem cells
A CU Cancer Center study published today in the journal Stem Cells shows that progenitor cells that create dangerous, muscle-invasive bladder cancer are different than the progenitor cells that create non-muscle invasive bladder cancer. Though these two cancers grow at the same site, they are different diseases.
National Institutes of Health

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 17-Dec-2013
Vaccine
Study: Moderate alcohol consumption boosts body's immune system
Medical science has known for years that people who drink moderate amounts of alcohol actually have a reduced risk of death. Now, new research from Oregon Health & Science University adds a fascinating twist: moderate drinking may actually bolster our immune system and help it fight off infection.
National Institutes of Health, NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Todd Murphy
murphyt@ohsu.edu
503-494-8231
Oregon Health & Science University

Public Release: 17-Dec-2013
Childhood Obesity
TV ads nutritionally unhealthy for kids, study finds
The nutritional value of food and drinks advertised on children's television programs is worse than food shown in ads during general air time, according to a new study.
US Centers for Disease Control and Prevention, NIH/National Cancer Institute, Robert Wood Johnson Foundation

Contact: Sherri McGinnis Gonzalez
smcginn@uic.edu
312-996-8277
University of Illinois at Chicago

Public Release: 17-Dec-2013
Nature Neuroscience
Silencing synapses
Imagine kicking a cocaine addiction by simply popping a pill that alters the way your brain processes chemical addiction. New research from the University of Pittsburgh suggests that a method of biologically manipulating certain neurocircuits could lead to a pharmacological approach that would weaken post-withdrawal cocaine cravings. The findings have been published in Nature Neuroscience.
National Institutes of Health National Institute on Drug Abuse, German Research Foundation

Contact: Joe Miksch
jmiksch@pitt.edu
412-624-4358
University of Pittsburgh

Showing releases 2901-2925 out of 3493.

<< < 112 | 113 | 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 > >>

     
   

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