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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 2951-2975 out of 3538.

<< < 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 > >>

Public Release: 30-Jan-2014
Cancer Research
Protein serves as a natural boost for immune system fight against tumors
Different molecular adjuvants, such as cytokines, are being studied as a way to increase the efficacy of vaccines. The development of DNA-based vaccines with cytokine adjuvants has emerged as particularly promising for inducing antiviral and anti-tumor, cell-mediated immune responses. The protein IL-33 boosts the immune system of a human papilloma virus animal model of cancer.
Basser Research Center for BRCA, National Institutes of Health

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 30-Jan-2014
Scripps scientist awarded $1.8 million to develop new approaches to lung cancer therapy
Scientists from the Florida campus of The Scripps Research Institute have been awarded approximately $1.8 million from the National Cancer Institute of the National Institutes of Health to identify the signaling pathways that underlie lung cancer and to use this information to develop new therapeutic approaches.
NIH/National Cancer Institute

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 30-Jan-2014
Cell
Worry on the brain
Previous studies of anxiety in the brain have focused on the amygdala, but a team of researchers led by biologists at Caltech had a hunch that understanding a different brain area, the lateral septum, could provide more clues into how the brain processes anxiety. Their instincts paid off -- the team has found a neural circuit that connects the LS with other brain structures in a manner that directly influences anxiety.
National Institutes of Health, Howard Hughes Medical Institute, Beckman Institute at Caltech

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Public Release: 30-Jan-2014
Cell
Researchers reverse some lung diseases in mice by coaxing production of healthy cells
Introducing proteins that direct lung stem cells to grow the specific cell types needed to repair lung injuries could lead to new ways to treat some lung diseases, according to research from Boston Children's Hospital published in the journal Cell.
Hope for Funds Cancer Research, NIH/National Heart, Lung, and Blood Institute, and others

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-7379
Boston Children's Hospital

Public Release: 30-Jan-2014
Cell Reports
Zebra fish fins help Oregon researchers gain insight into bone regeneration
University of Oregon biologists say they have opened the window on the natural process of bone regeneration in zebra fish, and that the insights they gained could be used to advance therapies for bone fractures and disease.
National Institutes of Health

Contact: Jim Barlow
jebarlow@uoregon.edu
541-346-3481
University of Oregon

Public Release: 30-Jan-2014
BioDataMining
Dartmouth researchers develop new tool to identify genetic risk factors
Dartmouth researchers developed a new biological pathway-based computational model, called the Pathway-based Human Phenotype Network, to identify underlying genetic connections between different diseases as reported in BioDataMining this week. The Pathway-based Human Phenotype Network mines the data present in large publicly available disease datasets to find shared SNPs, genes, or pathways and expresses them in a visual form.
National Institutes of Health

Contact: Donna Dubuc
Donna.M.Dubuc@Dartmouth.edu
603-653-3615
The Geisel School of Medicine at Dartmouth

Public Release: 30-Jan-2014
PLOS Genetics
Discovery may lead to new drugs for osteoporosis
Scientists at Washington University School of Medicine in St. Louis have discovered what appears to be a potent stimulator of new bone growth. The finding could lead to new treatments for osteoporosis and other diseases that occur when the body doesn't make enough bone.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine

Public Release: 30-Jan-2014
Nature
A protein-production tale of the tape
Whitehead Institute researchers have determined that poly(A) tails on messenger RNAs shift their role in the regulation of protein production during early embryogenesis. This finding about the regulation of messenger RNA translation also provides insight into how microRNAs control protein production.
National Institutes of Health

Contact: Nicole Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

Public Release: 30-Jan-2014
Science
UCSF team reveals how the brain recognizes speech sounds
UC San Francisco researchers are reporting a detailed account of how speech sounds are identified by the human brain. The finding, they said, may add to our understanding of language disorders, including dyslexia.
National Institutes of Health, Ester A. and Joseph Klingenstein Fund

Contact: Peter Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 30-Jan-2014
Journal of Investigative Medicine
Gastric banding patients should closely monitor nutrition following surgery
Patients who have had bariatric surgery may need to take dietary supplements and pay closer attention to their nutritional intake, a UT Southwestern Medical Center study suggests.
National Institutes of Health, Southwestern Medical Foundation

Contact: Debbie Bolles
debbie.bolles@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 30-Jan-2014
Cell
How DNA damage affects Golgi -- the cell's shipping department
In studying the impact of DNA damage on the Golgi, a research team from the University of California, San Diego School of Medicine and the Ludwig Institute for Cancer Research have discovered a novel pathway activated by DNA damage, with important consequences for the body's cellular response to chemotherapy.
National Institutes of Health, American Cancer Society

Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 30-Jan-2014
Cell
Cell cycle speed is key to making aging cells young again
Yale School of Medicine researchers identified a major obstacle to converting cells back to their youthful state -- the speed of the cell cycle, or the time required for a cell to divide. When the cell cycle accelerates to a certain speed, the barriers that keep a cell's fate on one path diminish. In such a state, cells are easily persuaded to change their identity and become pluripotent, or capable of becoming multiple cell types.
National Institutes of Health, Connecticut Stem Cell Research Program

Contact: Bill Hathaway
william.hathaway@yale.edu
203-432-1322
Yale University

Public Release: 30-Jan-2014
Stroke: Journal of the American Heart Association
Video game teaches kids about stroke symptoms and calling 9-1-1
Children improved their knowledge of stroke symptoms and how to respond after playing a stroke education video game. They retained that knowledge for several weeks.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Darcy Spitz
darcy.spitz@heart.org
212-878-5940
American Heart Association

Public Release: 30-Jan-2014
Cancer Prevention Research
New data contradict current recommendations for management of breast biopsy abnormalities
Contrary to existing understanding, long-term follow-up of patients with two types of breast tissue abnormalities suggests that both types of abnormalities have the same potential to progress to breast cancer, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. Findings from this study could improve clinical management of patients with breast tissue abnormalities.
National Institutes of Health, Susan G. Komen

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 30-Jan-2014
Science
Scientists discover new genetic forms of neurodegeneration
In a study published in the Jan. 31, 2014, issue of Science, an international team led by scientists at the University of California, San Diego, School of Medicine report doubling the number of known causes for the neurodegenerative disorder known as hereditary spastic paraplegia. The disorder is characterized by progressive stiffness and contraction of the lower limbs and is associated with epilepsy, cognitive impairment, blindness and other neurological features.
Deutsche Forschungsgemeinschaft, Brain & Behavior Research Foundation, and National Institutes of Health

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 29-Jan-2014
Proceedings of the National Academy of Sciences
Findings point to potential treatment for virus causing childhood illnesses
Researchers have discovered a potential treatment for a viral infection that causes potentially fatal brain swelling and paralysis in children. The findings also point to possible treatments for related viruses including those that cause "common cold" symptoms.
National Institutes of Health

Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University

Public Release: 29-Jan-2014
Nature
Puzzling question in bacterial immune system answered
Berkeley researchers have answered a central question about Cas9, an enzyme that plays an essential role in the bacterial immune system and is fast becoming a valuable tool for genetic engineering: How is Cas9 able to precisely discriminate between non-self DNA that must be degraded and self DNA that may be almost identical within genomes that are millions to billions of base pairs long.
National Science Foundation, National Institutes of Health

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory

Public Release: 29-Jan-2014
Progress in Community Health Partnerships: Research, Education and Action
U of Maryland study: Partnership may help address cancer, health disparities
Robust partnerships between rural community health education centers and academic health care institutions can make substantial strides toward addressing race-, income- and geographically based health disparities in underserved communities by empowering both the community and leading University institutions, according to newly published research from the University of Maryland School of Medicine.
NIH/National Cancer Institute, NIH/National Institute on Minority Health and Health Disparities

Contact: Christopher Hardwick
chardwick@som.umaryland.edu
410-706-5260
University of Maryland Medical Center

Public Release: 29-Jan-2014
Molecular Pharmacology
Obesity-induced fatty liver disease reversed in mice
Johns Hopkins researchers have discovered that valproic acid, a widely prescribed drug for treating epilepsy, has the additional benefits of reducing fat accumulation in the liver and lowering blood sugar levels in the blood of obese mice.
NIH/National Institute of General Medical Sciences

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Public Release: 29-Jan-2014
PLOS ONE
Lung and bladder cancers have common cell-cycle biomarkers
University of Colorado Cancer Center study shows bladder and lung cancers are marked by shared differences in the genetics that control the cell cycle. Measuring these genetic signatures could allow doctors to refine a patient's prognosis, choose appropriate treatments, and perhaps offer new treatments that target these shared genetic abnormalities.
NIH/National Cancer Institute, National Institutes of Health

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 29-Jan-2014
Endocrine-Related Cancer
Prostate cancer signal reawakens 'sleeper agent' cells in bones
Dormant prostate cancer cells in bone tissue can be reawakened to cause secondary tumors, according to new research published in Endocrine-Related Cancer. Targeting the wake-up call could prevent metastasis and improve prostate cancer survival rates.
NIH/National Cancer Institute, Prostate Cancer Foundation, and others

Contact: Omar Jamshed
omar.jamshed@bioscientifica.com
44-014-546-42206
BioScientifica Limited

Public Release: 29-Jan-2014
Menopause
Testosterone isn't the help some hoped for when women go through menopause early
With plummeting hormone levels, natural menopause before age 40 can put a damper on women's mental well being and quality of life. But bringing testosterone back up to normal may not bring them the boost some hoped for, found a new study published online today in Menopause, the journal of The North American Menopause Society.
NIH/Eunice Kennedy Shriver National Institute of Child Health, National Institutes of Health, Procter & Gamble

Contact: Eileen Petridis
epetridis@fallscommunications.com
216-696-0229
The North American Menopause Society (NAMS)

Public Release: 29-Jan-2014
Journal of the Acoustical Society of America
Decibels and democracy
Voice votes, common in civic and political decision making at all levels, can be skewed by a single, loud voice, according to a study led by the University of Iowa. The researchers propose locating everyone within equal distance from the vote recorder or controlling for sound on voters' microphones. Results appear in the Journal of the Acoustical Society of America.
National Institutes of Health

Contact: Richard Lewis
richard-c-lewis@uiowa.edu
319-384-0012
University of Iowa

Public Release: 29-Jan-2014
Science Translational Medicine
Vaccine used to treat cervical precancers triggers immune cell response
Preliminary results of a small clinical trial show that a vaccine used to treat women with high-grade precancerous cervical lesions triggers an immune cell response within the damaged tissue itself. The Johns Hopkins scientists who conducted the trial said the finding is significant because measuring immune system responses directly in the lesions may be a more accurate way to evaluate so-called "therapeutic" vaccines than by the conventional means of blood analysis.
NIH/National Cancer Institute

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 29-Jan-2014
Nature
Neanderthals' genetic legacy
Remnants of Neanderthal DNA in modern humans are associated with genes affecting type 2 diabetes, Crohn's disease, lupus, biliary cirrhosis and smoking behavior. They also concentrate in genes that influence skin and hair characteristics. At the same time, Neanderthal DNA is conspicuously low in regions of the X chromosome and testes-specific genes.
National Science Foundation, National Institutes of Health

Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School

Showing releases 2951-2975 out of 3538.

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