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Department of Health and Human Services

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Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 2951-2975 out of 3459.

<< < 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 > >>

Public Release: 24-Oct-2013
Science
What is it about your face?
Berkeley Lab researchers found thousands of gene enhancers -- regulatory sequences of DNA that act to turn-on or amplify the expression of a specific gene -- are involved in the development of the human face. These enhancers help explain why every human face is as unique as a fingerprint.
US Department of Energy, National Institutes of Health

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory

Public Release: 24-Oct-2013
PLOS Genetics
Genetic analysis reveals insights into the genetic architecture of OCD, Tourette syndrome
An international research consortium led by investigators at Massachusetts General Hospital and the University of Chicago has answered several questions about the genetic background of obsessive-compulsive disorder and Tourette syndrome, providing the first direct confirmation that both are highly heritable and also revealing major differences between the underlying genetic makeup of the disorders.
National Institutes of Health, Tourette Syndrome Association, David Judah Fund

Contact: Mike Morrison
mdmorrison@partners.org
617-724-6425
Massachusetts General Hospital

Public Release: 24-Oct-2013
Cell Reports
Researchers apply brainpower to understanding neural stem cell differentiation
How do humans and other mammals get so brainy? In a paper that will be published in Cell Reports on October 24, USC researcher Wange Lu, Ph.D., and his colleagues explained how neural stem and progenitor cells differentiate into neurons and related cells called glia. Neural stem and progenitor cells offer tremendous promise as a future treatment for neurodegenerative disorders, and understanding their differentiation is the first step towards harnessing this therapeutic potential.
National Institutes of Health

Contact: Cristy Lytal
lytal@med.usc.edu
University of Southern California - Health Sciences

Public Release: 24-Oct-2013
Science
Yeast, human stem cells drive discovery of new Parkinson's disease drug targets
Using a discovery platform whose components range from yeast cells to human stem cells, Whitehead Institute scientists have identified a novel Parkinson's disease drug target and a compound capable of repairing neurons derived from Parkinson's patients.
National Institutes of Health, Howard Hughes Medical Institute, JPB Foundation, Eleanor Schwartz Charitable Foundation, Bachmann Strauss Dystonia & Parkinson Foundation

Contact: Matt Fearer
fearer@wi.mit.edu
617-452-4630
Whitehead Institute for Biomedical Research

Public Release: 24-Oct-2013
American Society of Human Genetics Annual Meeting
Researchers identify gene variant that raises risk for colorectal cancer from eating processed meat
A common genetic variant that affects one in three people significantly increases the risk of colorectal cancer from the consumption of red meat and processed meat.
National Institutes of Health

Contact: Suzanne Wu
suzanne.wu@usc.edu
213-740-0252
University of Southern California

Public Release: 24-Oct-2013
Cell
Researchers design global HIV vaccine that shows promise in monkeys
The considerable diversity of HIV worldwide represents a critical challenge for designing an effective HIV vaccine. Now a scientific team led by Beth Israel Deaconess Medical Center has shown that mosaic antigens could be useful in the design of a global HIV vaccine.
Military HIV Research Program, National Institutes of Health, NIH/National Institute of Allergy and Infectious Diseases, Bill and Melinda Gates Foundation, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 24-Oct-2013
Stroke: Journal of the American Heart Association
Hands-free ultrasound device with clot-busting drug safe for stroke patients
A hands-free ultrasound device combined with clot buster was safe for ischemic stroke patients. The hands-free ultrasound device could help open up more arteries and improve patient outcomes.
National Institutes of Health

Contact: Karen Astle
karen.astle@heart.org
214-706-1392
American Heart Association

Public Release: 23-Oct-2013
Cell Cycle
Study: Metformin for breast cancer less effective at higher glucose concentrations
A University of Colorado Cancer Center study published online this month in the journal Cell Cycle shows that breast cancer cell growth, motility and aggression is promoted by excess glucose, as experienced by patients with diabetes and metabolic syndrome. The study also showed that patients with high glucose may require higher doses of the drug metformin to achieve the same anti-cancer activity as patients with normal glucose levels.
NIH/National Cancer Institute, National Institutes of Health, Komen

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 23-Oct-2013
PLOS ONE
USC researcher learns how to break a sweat
Without sweat, we would overheat and die. In a recent paper in the journal PLOS ONE, USC faculty member Krzysztof Kobielak and a team of researchers explored the ultimate origin of this sticky, stinky but vital substance -- sweat gland stem cells.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Marie Rippen
lytal@med.usc.edu
University of Southern California - Health Sciences

Public Release: 23-Oct-2013
Journal of Clinical Investigation
Cancer wasting due in part to tumor factors that block muscle repair, study shows
A new study reveals that tumors release factors into the bloodstream that inhibit the repair of damaged muscle fibers, and that this contributes to muscle loss during cancer wasting. The condition, also called cancer cachexia, accompanies certain cancers, causes life-threatening loss of body weight and is responsible for up to one-in-four cancer deaths. The condition has no treatment. The study points to new strategies and new drug targets for treating cancer cachexia.
NIH/National Cancer Institute, NIH/Center for Clinical and Translational Science

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 23-Oct-2013
Nature
Researchers capture images of open channel that moves proteins across cell membranes
Similar to passengers on an urban transit system, every protein made in the cell has a specific destination and function. Channels in cell membranes help direct these proteins to their appropriate target. Researchers at Boston University School of Medicine and their colleagues have now captured images of these channels as they open to allow proteins to pass through a membrane, while the proteins are being made.
NIH/National Institute of General Medical Sciences

Contact: Jenny Eriksen Leary
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center

Public Release: 23-Oct-2013
Anesthesiology
Neurotoxin effectively relieves bone cancer pain in dogs, Penn researchers find
By the time bone cancer is diagnosed in a pet dog, it is often too late to save the animal's life. Instead, the goal of treatment is to keep the dog as comfortable and free of pain as possible for as long as possible. A study by University of Pennsylvania veterinarians Dorothy Cimino Brown and Kimberly Agnello has demonstrated that a single spinal injection of a neurotoxin provided more relief from pain than the pain-relieving drugs that are typically used.
NIH/National Institute of Mental Health

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 23-Oct-2013
Clinical Cancer Research
A simple test may catch early pancreatic cancer
Reporting on a small preliminary study, Johns Hopkins researchers say a simple blood test based on detection of tiny epigenetic alterations may reveal the earliest signs of pancreatic cancer, a disease that is nearly always fatal because it isn't usually discovered until it has spread to other parts of the body.
National Cancer Institute, NIH/National Institute of Environmental Health Sciences

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine

Public Release: 23-Oct-2013
Bradley Hasbro Children's Research Center launches food allergy video game trial
Elizabeth McQuaid, Ph.D., a staff psychologist from the Bradley Hasbro Children's Research Center, is leading a research team testing a new interactive software game developed to help children with peanut allergies better manage allergy symptoms, social situations and proper food avoidance.
NIH/National Institute of Child Health & Human Development

Contact: Jill Reuter
jreuter@lifespan.org
401-444-6863
Lifespan

Public Release: 23-Oct-2013
Journal of Clinical Investigation
New eye treatment effective in laboratory tests
A promising technique for treating human eye disease has proven effective in preclinical studies and may lead to new treatments to prevent blindness, according to experiments conducted at The Scripps Research Institute in La Jolla, California. The studies involved controlling the actions of microRNAs, tiny pieces of RNA that were once considered to be "junk" but are now known to fine-tune gene activation and expression.
National Institutes of Health, Lowy Medical Research Institute, Manpei Suzuki Diabetes Foundation

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 23-Oct-2013
New England Journal of Medicine
Child born with HIV still in remission after 18 months off treatment, experts report
A three-year-old Mississippi child born with HIV and treated with a combination of antiviral drugs unusually early continues to do well and remains free of active infection 18 months after all treatment ceased, according to an updated case report published Oct. 23 in the New England Journal of Medicine.
National Institutes of Health, American Foundation for AIDS Research, International Maternal Pediatric Adolescent AIDS Clinical Trials Network, Collaboratory of AIDS Researchers for Eradication

Contact: Ekaterina Pesheva
epeshev1@jhmi.edu
410-502-9433
Johns Hopkins Medicine

Public Release: 23-Oct-2013
PLOS ONE
Oral bacteria create a 'fingerprint' in your mouth
The bacteria in the human mouth -- particularly those nestled under the gums -- are as powerful as a fingerprint at identifying a person's ethnicity, new research shows.
NIH/National Institute of Dental and Craniofacial Research

Contact: Purnima Kumar
Kumar.83@osu.edu
614-247-4532
Ohio State University

Public Release: 23-Oct-2013
Nature Communications
H5N1 bird flu genes show nature can pick worrisome traits
In the beginning, all flu viruses came from birds. Over time, the virus evolved to adapt to other animals, including humans, as natural selection favored viruses with mutations that allowed them to more readily infect the cells of new host species.
National Institutes of Health

Contact: Thomas Friedrich
thomasf@primate.wisc.edu
608-265-3381
University of Wisconsin-Madison

Public Release: 23-Oct-2013
Nature
How liver 'talks' to muscle: A well-timed, coordinated conversation
A major collaborative research effort involving scientists at Harvard School of Public Health, Brigham and Women's Hospital and Harvard University have uncovered a novel signal mechanism that controls how fat storage in the liver can communicate with fat burning in skeletal muscle.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital

Public Release: 22-Oct-2013
Cancer
Colon cancer screening guidelines may miss 10 percent of colon cancers
For people with a family history of adenomas (colon polyps that lead to colon cancer), up to 10 percent of colorectal cancers could be missed when current national screening guidelines are followed.
NIH/National Cancer Institute, Huntsman Cancer Foundation

Contact: Linda Aagard
801-587-7639
University of Utah Health Sciences

Public Release: 22-Oct-2013
American Journal of Public Health
Veterans who mismanage money four times more likely to become homeless
Military veterans who report having common financial problems, such as bouncing a check or going over their credit limit, are four times more likely to become homeless in the next year than veterans without such problems.
NIH/National Institute of Mental Health, US Department of Education

Contact: Tom Hughes
tahughes@unch.unc.edu
919-966-6047
University of North Carolina Health Care

Public Release: 22-Oct-2013
Journal of Attention Disorders
What a difference a grade makes
Children with attention problems that emerge in first grade show poorer school performance for years afterward, including scoring lower on fifth grade reading. The poor performance occurred even if the attention problems were fleeting and improved after first grade. By contrast, children who developed attention problems starting in second grade performed as well as their peers in later years.
NIH/National Institute of Mental Health, NIH/National Institute on Drug Abuse, US Department of Education

Contact: Alison Jones
alison.jones@duke.edu
919-681-8504
Duke University

Public Release: 22-Oct-2013
Proceedings of the National Academy of Sciences
Baby's innate number sense predicts future math skill
A new study from Duke suggests that the strength of an infant's innate sense of numerical quantities can be predictive of that child's mathematical abilities three years later.
National Institutes of Health, National Science Foundation, James McDonnell Scholar Award

Contact: Karl Leif Bates
karl.bates@duke.edu
919-681-8054
Duke University

Public Release: 22-Oct-2013
Proceedings of the National Academy of Sciences
New artificial protein mimics a part of the HIV outer coat
A team of scientists at Duke Medicine and Memorial Sloan-Kettering Cancer Center has created an artificial protein coupled with a sugar molecule that mimics a key site on the outer coat of HIV where antibodies can bind to neutralize a wide variety of HIV strains.
NIH/National Institute of Allergy and Infectious Diseases, Bill and Melinda Gates Foundation

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

Public Release: 22-Oct-2013
Proceedings of the National Academy of Sciences
Keeping it local: Protecting the brain starts at the synapse
New research by scientists at UC San Francisco shows that one of the brain's fundamental self-protection mechanisms depends on coordinated, finely calibrated teamwork among neurons and non-neural cells knows as glial cells, which until fairly recently were thought to be mere support cells for neurons.
University of California - San Francisco, National Institutes of Health

Contact: Peter Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco

Showing releases 2951-2975 out of 3459.

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