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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 2951-2975 out of 3398.

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Public Release: 10-Jun-2013
Cancer Research
Hormonal treatment for endometrial cancer does not directly target the malignant cells
Rogesterone, a female hormone that can be used as a therapy for endometrial cancer, eliminates tumor cells indirectly by binding to its receptor in connective tissue cells residing in the tumor microenvironment.
Charles Drew University, University of California, Los Angeles National Institutes of Health, Sidney Kimmel Foundation

Contact: Kim Irwin
University of California - Los Angeles Health Sciences

Public Release: 10-Jun-2013
Based on earlier successes, NIH awards new study in cancer research to Virginia Tech's Chang Lu
Preliminary results showing an ultrahigh sensitivity using a new technology for studying protein-DNA interactions has led to the National Institutes of Health's National Cancer Initiative award of $710,000 to Virginia Tech's Chang Lu of chemical engineering.
National Institutes of Health

Contact: Lynn Nystrom
Virginia Tech

Public Release: 10-Jun-2013
Proceedings of the National Academy of Sciences
A path to lower-risk painkillers
Could we be on the way to creating painkillers without side effects?
National Institutes of Health

Contact: Beata Mostafavi
University of Michigan Health System

Public Release: 10-Jun-2013
Journal of Radiation Oncology
Biodegradable implant may lessen side effects of radiation to treat prostate cancer
Several years ago, VCU Massey Cancer Center became the first center in the US to test an Israeli-invented device designed to increase the space between the prostate and the rectum in prostate cancer patients undergoing radiation therapy. Now, results from the international Phase I clinical trial show that the device has the potential to significantly reduce rectal injury, a side effect caused by unwanted radiation exposure that can leave men with compromised bowel function following treatment.
NIH/National Cancer Institute

Contact: John Wallace
Virginia Commonwealth University

Public Release: 10-Jun-2013
Aging Cell
Lifespan-extending drug given late in life reverses age-related heart disease in mice
Mice suffering from age-related heart disease saw a significant improvement in cardiac function after treatment with the FDA-approved drug rapamycin for just three months. Research at the Buck Institute shows how rapamycin impacts mammalian tissues, providing functional insights and possible benefits for a drug that can extend lifespan in mice as much as 14 percent. Researchers at the Mayo clinic are now recruiting seniors with cardiac artery disease for a clinical trial involving the drug.
National Institutes of Health, Larry L. Hillblom Foundation, Ellison Foundation, Glenn Foundations

Contact: Kris Rebillot
Buck Institute for Age Research

Public Release: 10-Jun-2013
Reduced brain volume in kids with low birth-weight tied to academic struggles
An analysis of recent data from magnetic resonance imaging of 97 adolescents who were part of study begun with very low birth weight babies born in 1982-1986 in a Cleveland neonatal intensive care unit has tied smaller brain volumes to poor academic achievement.
National Institutes of Health

Contact: Jim Barlow
University of Oregon

Public Release: 10-Jun-2013
A potential new target to thwart antibiotic resistance
Bacteria in the gut that are under attack by antibiotics have allies no one had anticipated, a team of Wyss Institute scientists has found. Gut viruses that usually commandeer the bacteria, it turns out, enable them to survive the antibiotic onslaught, most likely by handing them genes that help them withstand the drug. The results were reported online in Nature (June 9).
NIH/Director's Pioneer Award Program, Howard Hughes Medical Institute, Wyss Institute

Contact: Dan Ferber
Wyss Institute for Biologically Inspired Engineering at Harvard

Public Release: 10-Jun-2013
JACC: Cardiovascular Imaging
Study shows cardiac MRI use reduces adverse events for patients with acute chest pain
Wake Forest Baptist Medical Center doctors have found that using stress cardiac magnetic resonance imaging in an Emergency Department observation unit to care for patients with acute chest pain is a win-win -- for the patient and the institution.
NIH/National Heart, Lung, and Blood Institute

Contact: Bonnie Davis
Wake Forest Baptist Medical Center

Public Release: 10-Jun-2013
Proceedings of the National Academy of Sciences
Brain circuits link obsessive-compulsive behavior and obesity
A University of Iowa-led study suggests that the brain circuits that control obsessive-compulsive behavior are intertwined with circuits that control food intake and body weight. The team bred mice with a genetic mutation known to cause obesity, and suspected to also be involved in compulsive behavior, with a genetic mouse model of compulsive grooming. The experiment produced mice that were neither compulsive groomers nor obese.
National Institutes of Health, Hartwell Foundation, Brain and Behavior Foundation

Contact: Jennifer Brown
University of Iowa Health Care

Public Release: 10-Jun-2013
SLEEP 2013
Frequent binge drinking is associated with insomnia symptoms in older adults
A new study suggests that frequent binge drinking is associated with insomnia symptoms in older adults.
NIH/National Institute on Aging, NIH/National Institute on Drug Abuse

Contact: Lynn Celmer
American Academy of Sleep Medicine

Public Release: 10-Jun-2013
With new $1.7 million grant, U-M, Johns Hopkins researchers will develop dementia treatment tool
With the help of a $1.7-million grant from the National Institutes of Health (National Institute of Nursing Research), researchers from the University of Michigan and Johns Hopkins University will design an easy-to-use, web-based tool that helps caregivers track, understand and treat the behavioral symptoms of dementia.
NIH/National Institute of Nursing Research

Contact: Justin Harris
University of Michigan Health System

Public Release: 10-Jun-2013
Liver Transplantation
Split liver transplants for young children proven to be as safe as whole organ transplantation
A new study shows that when a liver from a deceased adult or adolescent donor is split into two separate portions for transplantation--with the smaller portion going to a young child and the larger to an adult--the smaller portion used for the child will last just as long as if the child had received a whole organ from a donor close to his size.
Agency for Healthcare Research and Quality, NIH/National Institute of Child Health and Human Development

Contact: Keri Stedman
Boston Children's Hospital

Public Release: 10-Jun-2013
Cost-effective: Universal HIV testing in India
A new study using a sophisticated statistical model, projects that providing universal HIV testing for India's billion-plus population every five years would prove to be a cost-effective approach to managing the epidemic, even with more intensive testing for high-risk groups. Results appear in the journal PLoS One.
NIH/National Institute of Allergy and Infectious Disease

Contact: David Orenstein
Brown University

Public Release: 10-Jun-2013
Annals of Internal Medicine
Medicare beneficiaries substantially more likely to use brand-name drugs than VA patients
Medicare beneficiaries with diabetes are two to three times more likely to use expensive brand-name drugs than a comparable group of patients treated within the VA Healthcare System, according to a nationwide study by researchers from the University of Pittsburgh, VA Pittsburgh Healthcare System and Dartmouth College. Spending in Medicare Part D would have been an estimated $1.4 billion less in 2008 if brand-name drug use matched that of the VA for the medications studied.
Veterans Affairs, National Institutes of Health, Robert Wood Johnson Foundation

Contact: Cyndy McGrath
University of Pittsburgh Schools of the Health Sciences

Public Release: 10-Jun-2013
JAMA Pediatrics
CT scans -- with radiation and cancer risk -- rose in children
Use of computed tomography scans -- and thus exposure to ionizing radiation -- increased over 15 years in children at a set of nonprofit health care delivery systems in a new study. But currently available strategies could greatly reduce this cancer risk, according to the HMORN Cancer Research Network study, published in JAMA Pediatrics.
NIH/National Cancer Institute, National Institutes of Health

Contact: Rebecca Hughes
Group Health Research Institute

Public Release: 10-Jun-2013
JAMA Pediatrics
Reducing unnecessary and high-dose pediatric CT scans could cut associated cancers by 62 percent
A study examining trends in X-ray computed tomography use in children in the United States has found that reducing unnecessary scans and lowering the doses for the highest-dose scans could lower the overall lifetime risk of future imaging-related cancers by 62 percent.
NIH/National Cancer Institute

Contact: Phyllis Brown
University of California - Davis Health System

Public Release: 10-Jun-2013
Journal of Studies on Alcohol and Drugs
Nearly a fifth of designated drivers are impaired
They may volunteer to be the one to get their friends home safely, but "designated drivers" often drink -- even to a level that impairs them behind the wheel, according to a report in the July issue of the Journal of Studies on Alcohol and Drugs.
National Institutes of Health

Contact: Allison Vitt
Journal of Studies on Alcohol and Drugs

Public Release: 10-Jun-2013
Journal of Clinical Investigation
DNA-altering enzyme is essential for blood cell development
In this issue of the Journal of Clinical Investigation, Scott Hiebert and colleagues at Vanderbilt University examined the role of HDAC3 in the development of blood cells by disrupting its expression in mice.
National Institutes of Health, Vanderbilt Digestive Disease Research, Vanderbilt-Ingram Cancer Center

Contact: Jillian Hurst
Journal of Clinical Investigation

Public Release: 9-Jun-2013
Mice give new clues to origins of OCD
Columbia Psychiatry researchers have identified what they think may be a mechanism underlying the development of compulsive behaviors. The finding suggests possible approaches to treating or preventing certain characteristics of OCD.
NIH/National Institute of Mental Health, Louis V. Gerstner, Jr. Scholars Program, Irving Institute for Clinical and Translation Research

Contact: Karin Eskenazi
Columbia University Medical Center

Public Release: 9-Jun-2013
Scientists identify potential drug target for treatment-resistant anemias
Researchers at Whitehead Institute have identified a key target protein of glucocorticoids, the drugs that are used to increase red blood cell production in patients with certain types of anemia, including those resulting from trauma, sepsis, malaria, kidney dialysis, and chemotherapy. The discovery could spur development of drugs capable of increasing this protein's production and thus increased numbers of red blood cells without causing the severe side effects associated with glucocorticoids.
National Institutes of Health, Singapore-Massachusetts Institute of Technology Alliance

Contact: Nicole Rura
Whitehead Institute for Biomedical Research

Public Release: 9-Jun-2013
Nature Neuroscience
3-D map of blood vessels in cerebral cortex holds suprises
Blood vessels within a sensory area of the mammalian brain loop and connect in unexpected ways, a new map has revealed.
National Institutes of Health

Contact: David Kleinfeld
University of California - San Diego

Public Release: 9-Jun-2013
Nature Neuroscience
Gladstone scientists map process by which brain cells form long-term memories
Scientists have deciphered how a protein called Arc regulates the activity of neurons--providing much-needed clues into the brain's ability to form long-lasting memories. These findings, reported today in Nature Neuroscience, also offer newfound understanding as to what goes on at the molecular level when this process becomes disrupted.
NIH/National Institute of Neurological Disease and Stroke, National Institute on Aging, Keck Foundation

Contact: Anne Holden
Gladstone Institutes

Public Release: 6-Jun-2013
American Journal of Human Genetics
Common genetic disease linked to father's age
Scientists at USC have unlocked the mystery of why new cases of the genetic disease Noonan syndrome are so common; a mutation that causes the disease disproportionately increases a normal father's production of sperm carrying the disease trait.
NIH/National Institute of General Medical Sciences, NIH/National Heart, Lung and Blood Institute

Contact: Robert Perkins
University of Southern California

Public Release: 6-Jun-2013
Researchers discover normal molecular pathway affected in poor-prognosis childhood leukemia
Through genetic engineering of laboratory models, researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center have uncovered a vulnerability in the way cancer cells diverge from normal regenerating cells that may help treat children with leukemia as reported in the journal PNAS on June 3, 2013.
National Institutes of Health

Contact: Donna Dubuc
Dartmouth-Hitchcock Medical Center

Public Release: 6-Jun-2013
$18 million to study deadly secrets of flu, Ebola, West Nile viruses
In an effort to sort out why some viruses such as influenza, Ebola and West Nile are so lethal, a team of US researchers plans a comprehensive effort to model how humans respond to these viral pathogens.
National Institutes of Health

Contact: Yoshihiro Kawaoka
University of Wisconsin-Madison

Showing releases 2951-2975 out of 3398.

<< < 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 > >>


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